Atletico Madrid have been left with it all to do in the Copa del Rey quarter-finals as a late Miguel Angel Moya own goal was followed by a Joaquin Correa winner in Sevilla's shock 2-1 triumph at the Wanda Metropolitano.
Diego Costa's third goal in four games since re-joining Atletico arrived 17 minutes from time and appeared to have secured the hosts a slender first-leg victory, but a fortuitous Moya own goal after a Jesus Navas cross made things interesting.
Then, with only two minutes left, Joaquin Correa punished Atletico on the break to secure a fine result.
There was little indication of the two teams' contrasting recent fortunes during the first half, as Sevilla – who had won just two of their previous eight in all competitions – gave as good as they got in an entertaining encounter.
Joaquin Correa, Pablo Sarabia and Sergio Escudero all went desperately close for the visitors, while Costa twice troubled Sergio Rico in the Sevilla goal.
Former Chelsea star Costa had seemingly ended Sevilla's resistance when he scored fairly late in the day with an emphatic left-footed strike.
1 - Sevilla are the first Spanish team to win against Atletico at Wanda Metropolitano in all competitions. Historic. pic.twitter.com/vwAEaL9vTB— OptaJose (@OptaJose) January 17, 2018
But Sevilla rallied brilliantly to somehow leave the Wanda with a result that means they will take a surprise lead to the typically raucous Ramon Sanchez Pizjuan for next Tuesday's second leg.
Despite seeing much less of the ball than Atletico, Sevilla arguably looked the more threatening going forward at times in the first half.
Franco Vazquez fired just wide from 18 yards early on, before Sarabia hit a half-volley on the spin from a similar distance which agonisingly missed the top-right corner.
Atletico and Costa soon woke up, however.
The Spain international saw a headed goal disallowed 13 minutes in after tussling with Gabriel Mercado at a corner and forced Sevilla goalkeeper Rico to brilliantly turn another header around the post soon after.
Sevilla remained a potent threat on the break and should have scored just before the half-hour mark, but Joaquin Correa shot straight at Moya when through on goal.
The end-to-end nature of proceedings continued right until the break – Costa again testing Rico from a tight angle after a swift counter, before Moya tipped Escudero's spectacular long-range effort over.
Vitolo – who departed Sevilla in a contentious transfer in July – was so ineffective against his former employers that Diego Simeone opted to hook him for Angel Correa at the break, and the substitute caused trouble almost straight away with his crossing.
His first delivery across the face of goal was nearly turned in by Costa, before Clement Lenglet headed the forward's second cross onto his own post.
There was to be no denying Costa in the 73rd minute, however, as the lively striker lashed a left-footed drive into the bottom-right corner after Sevilla failed to clear a free-kick.
But the visitors were by no means out of it.
Substitute Navas played a pivotal – albeit lucky – role in the equaliser, as his right-wing cross took a deflection off Lucas Hernandez and found its way in via the glove of Moya.
And Joaquin Correa then secured Sevilla's first win at Atletico in any competition since September 2008, racing onto Wissam Ben Yedder's pass and prodding cleverly past the helpless Moya to set up a tantalising second leg.
|Italy to name new coach in May, Costacurta confirms|
|Canada 1 New Zealand 0: Herdman enjoys winning start thanks to Ricketts|
|Wilshere withdraws from England squad to face Italy|
|Colombia collapse a slap for France, says Giroud|
|Vazquez wants Spain to face Messi|
|Gotze, Sahin mentoring Jadon Sancho at Dortmund|
|Low to make changes for Brazil friendly as injured Can heads home|
|Conti targets Milan derby for injury return|
|Northern Ireland 2 South Korea 1: Son frustrated as World Cup preparations stutter|
|Olympiacos & Nottingham Forest owner denies any wrongdoing over drug trafficking charges|
|Two games in two days! Ireland´s Doyle returns from Turkey to play for Bradford|
|Everything is fine again! Khedira offers positive fitness update|
|Puyol ´doesn´t see any problem´ with Neymar joining Real Madrid|
|Spain already know their team - Sampaoli seeks Argentina certainty|
|No offers for ´happy´ Bellerin, insists Arsenal full-back´s agent|
|Iker is trembling already! - Ramos hunting down Casillas´ cap record|
|Silva leaves Spain squad for personal reasons|
|Egypt coach Cuper declares Salah among world´s best|
|A-League Review: Simon haunts managerless Mariners, Jakobsen opens City account|
|Ronaldo trumps Salah, Messi missing - winners and losers from Friday´s internationals|
|Giggs wants Bale to stay at Real Madrid|
|Muller and Ozil set to miss Brazil friendly|
|Ramos hails Spain´s belief after Germany draw|
|Buffon not ready to walk away as Italy look to the future|
|Mexico 3 Iceland 0: Layun scores brace in friendly win|
|Usain Bolt not ready for top level, says Stoger|
|Ronaldo is a goal – Santos hails Portugal star|
|Dybala and Icardi World Cup chances not over yet, says Sampaoli|
|James: Colombia can´t get carried away with France win|
|Italy to wait on Verratti injury|
|Lopetegui happy with Spain showing against ´physically stronger´ Germany|
|Messi has had hamstring injury for ´some time´|
|Forward-thinking Southgate makes case for England´s defence|
|McLeish to ring Scotland changes for Hungary clash|
|Rodrigo dedicates Spain goal to Canizares after death of son|
|France were taught a lesson in aggression by Colombia, says Deschamps|
|Ronaldo up to third on all-time list after Portugal brace|
|Meunier expects PSG will sack Emery|
|Germany friendly emotionally important for Brazil - Tite|
|France 2 Colombia 3: Quintero completes stunning comeback in Paris|
|Portugal 2 Egypt 1: Late Ronaldo double stuns Salah-inspired Pharaohs|
|No Messi, no Magic – Sampaoli playing a risky game ignoring Dybala|
|Netherlands 0 England 1: Lingard strikes to ruin Koeman´s debut|
|Scotland 0 Costa Rica 1: McLeish suffers defeat in first game back|
|Argentina 2 Italy 0: Banega & Lanzini win it for Messi-less Albiceleste|
|Germany 1 Spain 1: Muller wonderstrike cancels out Rodrigo opener|
|Ibrahimovic: If I want to go to the World Cup, I´m there|
|Australia not ready for World Cup – Van Marwijk|
|Turkey 1 Republic of Ireland 0: Topal strike downs O´Neill´s men|
|Norway 4 Australia 1: Kamara hat-trick spoils Van Marwijk´s Socceroos bow|
|Aguero to miss Argentina friendlies|
|Monaco rubbish reports Rybolovlev will sell club and buy AC Milan|
|Messi misses Argentina-Italy game|
|Neuer cautious over comeback date despite taking positive steps|
|Everton defender Holgate warned for alleged homophobic tweets|
|Di Maria predicts ´big change´ at PSG after Champions League failure|
|Russia 0 Brazil 3: Coutinho on target in routine win|
|Icardi must keep performing to earn Argentina recall, says Zanetti|
|Different place, same Zlatan - Ibrahimovic determined to maintain winning DNA with LA Galaxy|
|Experience the key for Juventus in title race, insists Trezeguet|
|Messi lacks Maradona´s charisma, claims Batistuta|
|Usain Bolt claims he´ll return to Dortmund|
|Trezeguet confident Pogba will shine at the World Cup|
|Ibrahimovic departs Europe with remarkable haul of league titles|
|´Very, very happy´ Lanzini loves West Ham amid transfer talk|
|LA Galaxy confirm Ibrahimovic arrival|
|Age no barrier to Messi brilliance - Kluivert|
|Japan 1 Mali 1: Late Nakajima strike earns a draw|
|Uruguay 2 Czech Republic 0: Suarez scores 50th international goal|
|I choose the Galaxy! - Ibrahimovic confirms LA switch|
|Roberto Carlos declares Neymar and Brazil the World Cup favourites|
|Kluivert tells son Justin to snub Manchester United for Barcelona|
|Reading appoint former Swansea boss Clement|
|I had to get out of my comfort zone - Goretzka explains Bayern switch|
|Adelaide United 5 Newcastle Jets 2: Five-star Reds end winless streak|
|Goals, nutmegs and cheers - Usain Bolt impresses in Borussia Dortmund training|
|De Bruyne: Don´t compare me to Messi and Ronaldo|
|Real Madrid can win the Champions League, Roberto Carlos claims|
|Martinez determined to earn World Cup place|
|Arthur ´counting the days´ to Barcelona switch|
|English football must address racism, says Southgate|
|Alisson can be world´s best – Taffarel|
|Ter Stegen dismisses ´Messi with gloves´ label|
|Buffon: Messi more complete than Ronaldo|
|Neymar is irreplaceable, says Tite|
|Conti: Milan much better thanks to Gattuso|
|Show must go on in Hollywood! - Pogba and Mkhitaryan say Ibrahimovic goodbyes|
|Arthur: I´ll find out if Messi is from this planet|
|Barcelona better than Real Madrid even if Neymar signs - Iniesta|
|I haven´t booked a holiday yet - Leno hoping for World Cup call|
|I may be 40 but I´m still Juve´s number one – Buffon bullish over Italy return|
|Italy coach Di Biagio dismisses Raiola rage over Balotelli snub|
|Lopetegui not ruling out Martinez World Cup chances|
|Spain defender Ramos targeting Casillas caps record|
|Pogba gets no special treatment from Deschamps|
|Ibrahimovic to LA Galaxy? Beckham, Drogba, Pirlo and the other stars to try MLS|
|Wilshere out for England with Pickford to face Netherlands|
|Southgate rejects England safety concerns over World Cup|
|Great things come to an end - Ibrahimovic confirms Man Utd departure|
|This is Messi´s team - Sampaoli puts faith in Barcelona superstar|
|Juventus to play in MLS All-Star Game|
|Low confirms Can will miss Spain game|
|Ibrahimovic released by Manchester United|
|Santos not interested in Ronaldo to China links|
|WATCH: Messi scores superb solo strike in Argentina training|
|Koeman names Van Dijk new Netherlands captain|
|Dybala and Icardi´s World Cup hopes doused by Sampaoli|
|I almost s*** myself - Pique on Keane rant|
|UEFA order PSG to close Auteuil stand|
|Brilliant Bale basks in Wales record|
|Neuer needs to play to make Germany´s World Cup squad – Low|
|China 0 Wales 6: Record-breaking Bale leads demolition job in perfect start for Giggs|
|Bale becomes Wales´ record goalscorer with China hat-trick|
|The ´reality for people with a brain´ is Manchester United are in transition, Mourinho claims|
|West Ham ban disruptive fans for life after Burnley chaos|
|Iniesta hints at post-World Cup international retirement|
|All we do is talk s*** - Pique goads Madrid stars over WhatsApp|
|Euro 2016 humiliation helped England, claims Dele Alli|
|Iniesta confident of two more years in Barcelona starting XI|
|Kane probably the best striker in the world - Maguire|
|Wenger told Wilshere he could leave Arsenal|
|If you play for Atletico, you must be committed – Koke responds to Griezmann speculation|
|Giggs: Bale will feature for Wales in China Cup|
|Maradona: Messi doesn´t have to prove himself by winning World Cup|
|Cristiano Ronaldo hasn´t asked to leave Real Madrid amid China links – Perez|
|Manchester United apply for professional women´s team|