Nkana venture into uncharted waters on Saturday as they face Al Ahly in the group stages of the CAF Confederation Cup.
The Zambian Premier League champions are one of six teams who make up the last eight of the competition having started the season in the CAF Champions League.
A daunting trip to eight-time Champions League winners Al Ahly awaits them in Group B, which also contains Sewe Sport and Etoile du Sahel.
Al Ahly are competing in the Confederation Cup for the first time after suffering the disappointment of elimination from Africa's elite club competition, and coach Fathi Mabrouk is not concerned about their opening game.
"We have a strong team, same with our opponents, but I think it's our pedigree and determination to win that sets us apart," he said.
"The game against Nkana is important. It will set the tone for our campaign.
"They were here last month but I did not have the opportunity to watch them. It's, however, not something to worry us, we know their style."
The visit to Egypt will bring back painful memories for Nkana, who were knocked out of the Champions League by Al Ahly's fierce rivals Zamalek, losing 5-0 in Cairo in March.
With defending champions CS Sfaxien not playing in the competition this season the most recent winners left are Leopards, and the Congolese side, who triumphed in 2012, host Cotonsport in Group A.
Leopards needed penalties to make it into the group stages at the expense of Medeama, and they face their Cameroonian opponents for the first time since 2010.
That was a first-round match in the same competition, with Cotonsport progressing on away goals after the two-legged tie had finished 3-3.
The other game in Group A sees Real Bamako face ASEC Mimosas, the Ivorians one of the two sides who have been in the competition from the start.
ASEC have only conceded three goals in their six games so far in the competition and will hope their mean defence can enable their free-scoring strikers, who have netted12 goals, to secure victory.
Sewe Sport will take part in the group stages for the first time when they host former winners Etoile in Abidjan.
Etoile lifted the trophy in 2006 and were runners-up two seasons later but have concentrated their focus on the Champions League in recent seasons.
The Tunisian side have already beaten Congo's CARA Brazzaville, Supersport United from South Africa and Guinea champions Horoya in the competition and will be confident of starting the group stages with a win.
|Gerard sacked as Barca B coach after woeful winless run|
|Bayern links ´an honour´ for Madrid man Bale|
|Roma ashamed by Liverpool fan attack|
|UEFA ´shocked by vile attack´ on Liverpool fan|
|Campbell tips Vieira and Bergkamp to replace Wenger|
|Courtois to sue former Belgium coach Wilmots|
|Heavyweights Ronaldo and Lewandowski go head to head – Champions League in Opta numbers|
|Copa Libertadores Review: Gabriel leads Santos, Atletico cruise|
|He decides the biggest moments – Wijnaldum hails Salah|
|Roma have some hope, says Monchi|
|Messi? Ronaldo? Salah is world´s best player – Gerrard|
|Liverpool are not Barcelona – Klopp cautious of Roma comeback|
|Liverpool supporter in ´critical condition´ after fan clashes|
|It´s all-inclusive football with Liverpool! - Klopp pleased despite Roma recovery|
|Montella to remain Sevilla coach until end of season|
|Di Francesco: Roma gave up – but if you don´t believe in a comeback, stay at home|
|Klopp accepts Salah substitution sparked Roma fightback|
|Oxlade-Chamberlain may miss World Cup after suffering ´a really bad injury´|
|De Rossi blames long balls for Roma ´blackout´ at Anfield|
|Late Liverpool lapses sour stunning Salah show|
|Henderson wary of Barcelona repeat as Roma leave Liverpool with hope|
|Championship Review: Cardiff slip up as Barnsley stay in the relegation zone|
|Liverpool 5 Roma 2: Salah shines but late comeback offers Giallorossi hope|
|Salah sets Liverpool record with spectacular first-half double|
|Oxlade-Chamberlain carried off in Champions League semi-final|
|Firmino back, as Milner starts for Liverpool against Roma|
|I didn´t want James to go - Zidane ready for Champions League reunion with familiar face|
|Kroos: You can´t buy the Champions League|
|Leeds urged to help Rohingya during ´odd´ Myanmar tour|
|Buffon slams reports of breakdown in Benatia relationship|
|Former France coach Michel dies aged 70|
|Ancelotti talks not about Italy job, says Costacurta|
|It was a weird few days - FA Cup final ref Oliver reflects on Buffon incident|
|Boateng not intimidated by supreme athlete Ronaldo|
|Heynckes: James was depressed after Real Madrid exit|
|Worry about Ronaldo? Real Madrid should fear Lewandowski, says Heynckes|
|Supporter tensions have affected Wenger - Rice|
|Germany submits Euro 2024 bid dossier|
|If Lewandowski wants to go, Bayern will have to let him – Effenberg|
|´Goal machine´ Ronaldo more complete than Messi – Kimmich|
|Bayern Munich v Real Madrid: Is this the end of the ´BBC´?|
|Zidane taking entire Madrid squad to Munich|
|Buffon reaction to Real Madrid penalty ´understandable´ – UEFA president|
|Liverpool owner was ´bitching´ about overpaying for Salah – Roma president|
|Liverpool Salah v Roma Salah: The Opta numbers|
|Salah eyes Reds record, Roma´s away-day struggles - Champions League semi-final in Opta numbers|
|The Spanish Inquisition - Bayern´s UCL hoodoo vs LaLiga´s big boys|
|Dani Alves: I´d return to Barcelona tomorrow|
|No friendly Roma reunion for Salah, warns Klopp|
|WATCH: Translator wins Klopp´s approval after lengthy response|
|Swap spaghetti for burgers? Di Francesco not considering Premier League move|
|Allardyce hits back at style critics after scrappy Everton win|
|Nothing to prove - Cahill bullish after Chelsea revival|
|Everton 1 Newcastle United 0: Walcott scuppers Benitez´s century celebrations|
|Everton debut ´virtual mascot´ before Newcastle clash|
|Salah? I can count on Cengiz Under – Di Francesco|
|´Shameful´ Bolivian side forfeit match at 7-0 down after fielding youth team|
|Henderson fired up for ´fantastic´ De Rossi battle|
|Klopp urges Liverpool fans to ´show respect´ to Roma|
|Juventus confirm muscle tear for Chiellini|
|Klopp key to surprising Salah success – Totti|
|Salah´s PFA award made more special by De Bruyne form – Klopp|
|Liverpool have earned the right to be feared, says Gerrard|
|Arsenal confirm ankle ligament damage for Elneny|
|Hector pledges future to struggling Cologne|
|´Crazy´ fans can help Roma knock out Liverpool, says Voller|
|He keeps getting better and better - Henderson full of praise for PFA winner Salah|
|Roma v Liverpool: Giallorossi have chance to write positive headlines|
|Wenger will not be short of offers from clubs - Dein|
|I may play the kids in the FA Cup next season, reveals bemused Pochettino|
|Simeone weighing up three-man defence for Arsenal tie|
|Vieira refuses to address Arsenal rumours and Wenger departure|
|Man United star Pogba can win Ballon d´Or, says Ronaldinho|
|Silva loves me more than his girlfriend – Mendy|
|MLS Review: Timbers end NYC´s unbeaten start, Sounders claim first win|
|Emery praises PSG for maintaining motivation|
|Oblak unsure over Atletico Madrid future|
|Klopp ready for ´different´ Roma test|
|Salah always determined to prove his Premier League worth|
|City´s Sane named PFA Young Player of the Year|
|Salah pips De Bruyne to PFA Players´ Player of the Year award|
|Napoli bus spat at and insulted, Sarri claims|
|Navas will be at Real Madrid for many years – Perez|