Benfica won 2-0 at Arouca on Sunday to move within a victory of the Primeira Liga title, although an injury to Jan Oblak caused concern.
Benfica came into the fixture four points clear of local rivals Sporting Lisbon, who sit second, but now hold a seven-point advantage with just three matches left to play.
Rodrigo's fourth goal in his last three matches put the visitors ahead in first-half stoppage time after the Arouca defence failed to clear their lines from a Lima cross.
And Nicolas Gaitan made sure of the points 10 minutes into the second half, although there were worrying scenes when goalkeeper Oblak was injured following a clash of heads and briefly lost consciousness.
He was later taken to hospital to be monitored.
Benfica will be hoping for positive news on his condition as they return to training next week, with a clash against rock-bottom Olhanense on Saturday giving them the chance to win the league.
Arouca, meanwhile, are not yet assured of safety, sitting two points clear of the relegation play-off position in 13th.
In Sunday's other match, Porto needed goals from Carlos Eduardo and Juan Quintero in the last four minutes to give them a 3-1 win at Sporting Braga.
The result saw Porto bounce back from their UEFA Europa League elimination at Sevilla on Thursday and strengthen their grip on the third and final UEFA Champions League spot.
Silvestre Varela sent the reigning champions into a 23rd-minute lead with a delicate chipped finish, but Erik Moreno pegged them back with a header shortly before the hour-mark.
Brazilian Eduardo restored Porto's advantage four minutes from time though, and Quintero's stoppage-time effort sealed the points.
Victory lifts Porto nine points clear of the fourth-placed Estoril, who face Pacos de Ferreira tomorrow, while Braga's hopes of European football next season are fading.
|Moyes unaware of Chelsea interest in Carroll|
|Verdi wants Bologna stay amid Napoli links|
|Ronaldinho retires – A shining light of Brazil´s 2002 World Cup-winning team|
|Ronaldinho retires – a World Cup and Ballon d´Or among Brazil great´s prizes|
|World Cup glory and Bernabeu magic - Ronaldinho´s best moments for Barca and Brazil|
|Ligue 1 Review: Balotelli at the double as Payet shines and Malcom toils|
|Pato still dreaming of World Cup selection|
|FA Cup Review: Iheanacho makes VAR history, kit confusion reigns|
|2016-17 UEFA Study: PSG, Man City drive record-breaking spending|
|Conte packing in homework as Chelsea games stack up|
|2016-17 UEFA Study: Manchester United record highest revenue but largest debt|
|2016-17 UEFA Study: The headlines in transfers, wages and revenues|
|Iheanacho scores English football´s first VAR goal|
|Materazzi not surprised by Coutinho transfer fee|
|Ronaldinho retires - Brazil and Barca great plans 2018 farewell|
|Koziello swaps Nice for Cologne|
|Simeone ready to unleash Costa and Vitolo alongside Griezmann|
|Lambert ´never thought´ he would return to Premier League|
|Wenger ´very aggressive´ towards referee Dean, says FA report|
|Reported Arsenal target Malcom starts for Bordeaux vs Caen|
|Valverde not making big deal of Dembele´s latest Barca blow|
|Arsenal will have a ´hard time´ signing Malcom|
|Ronaldo and Madrid nominated for Laureus awards|
|Nantes´ Diego Carlos brands Chapron clash ´historic´|
|This is not important - Conte unconcerned if substitutions upset Hazard|
|Conte ´doesn´t think´ Chelsea have pursued Sanchez|
|Emery hints at Neymar return against Dijon|
|Mkhitaryan key to United-Sanchez deal, claims Raiola|
|Tevez: CSL spell was a holiday|
|Mignolet considering Liverpool future|
|Fred waiting for Guardiola call amid Man City speculation|
|Inter confident but patient over Rafinha|
|Giggs had counselling after Old Trafford exit|
|Neville: Mourinho would happily swap Mkhitaryan for Sanchez|
|Man United becoming Pogba´s team – Mourinho|
|Can ´talking with everyone´ but hints at Liverpool stay|
|Mourinho ´not unconfident´ Manchester United will sign Sanchez|
|Pogba warns City that United will not give up the chase|
|Assist king Pogba matches De Bruyne, Sane despite injury and suspension|
|Manchester United 3 Stoke City 0: Valencia, Martial and Lukaku trim gap at the top|
|Shaw feeling on top of his game amid United run|
|Mkhitaryan left out by Manchester United amid Arsenal talk|
|Inter secure Lopez on loan from Benfica|
|Hurst marvels at hat-trick maestro Kane|
|WATCH: Neymar nutmegging for fun in PSG training|
|Nantes´ Carlos has red card overturned after being kicked by referee|
|´Logical´ for Aubameyang to stay at Dortmund, says Stoger|
|Stupid not to - Giggs seeks Fergie´s advice upon taking Wales job|
|Suarez feared Chiellini bite would derail Barca transfer|
|Dortmund sign reported Man United target Akanji|
|Wales confirm Giggs appointment|
|Barcelona´s Dembele out for up to four weeks|
|Struggling Stoke appoint Lambert|
|Referee suspended until further notice after kicking Nantes´ Carlos|
|Coutinho´s ´deserved´ Barca move, says Figo|
|Fatigue the issue for goal-shy Chelsea - Conte|
|West Brom legend Regis dies aged 59|
|Mourinho: I don´t like feuding with managers|
|Puel confident of keeping Mahrez at Leicester|
|Valverde: Real Madrid haven´t given up on LaLiga|
|Ibrahimovic nearing end at top level – Mourinho|
|David is to keep - Mourinho wants new Man United deal for De Gea|
|Nantes president demands ban after referee kicks Carlos|
|Stoger sets out rules for Aubameyang reintegration at Dortmund|