Beijing Guoan will hope to leapfrog reigning champions Guangzhou Evergrande in the 12th round of the Chinese Super League season.
Evergrande lost their derby against Guangzhou R&F last week, which allowed Beijing to draw level on points at the top of the CSL table.
Moroccan striker Abderrazak Hamdallah scored the only goal in R&F's 1-0 victory, cutting inside to blast the ball past Evergrande goalkeeper Zeng Cheng on the hour mark.
Evergrande followed up their derby loss with a 1-0 loss to Cerezo Osaka in the AFC Champions League (ACL) on Tuesday, although they still advanced to the quarter-finals 5-2 on aggregate.
Beijing, currently second on goal difference, will overhaul Evergrande with at least a draw at Shanghai Shenxin on Saturday. And they will remain on top if the title-holders fail to match Guoan's result at Hangzhou on Sunday.
In a boost for Beijing, Hangzhou have a strong home record with just one loss at their Yellow Dragon Sports Center since August, while Shenxin have not won in five games.
Beijing defeated Liaoning Whowin 1-0 last week thanks to a very late penalty from Pablo Batalla.
In the sixth minute of second-half stoppage time, Liaoning's Yang Yu was penalised for handling in the area and Batalla made no mistake from 12 yards.
The win took Beijing to 27 points, level with Evergrande, although the latter have a far superior goal difference.
Batalla looks set to be critical to Beijing's chances, the Argentine attacking midfielder having scored six of his side's 12 goals in the CSL this season.
Ecuadorian striker Joffre Guerron has hit the back of the net four times, although three of his goals have come in the ACL.
If both Beijing and Evergrande falter over the weekend, third-placed R&F could move to within two points of the summit by beating Guizhou Renhe on Sunday.
R&F are on a six-game unbeaten run and will travel to Guizhou hoping to inflict further pain on their hosts, after Renhe were thumped 5-2 by Shanghai SIPG last week.
Shandong Luneng, who slumped to fourth last week after a third straight loss, will hope to bounce back against Shanghai SIPG, while Liaoning host Henan Jianye in a battle of two struggling sides.
In other fixtures, Shanghai Shenhua will travel to Harbin Yiteng, Tianjin Teda face Changchun Yatai and Jiangsu Sainty meet Dalian Aerbin.
|Warm Dortmund welcome delights Tuchel|
|Silva vows to fight for Madrid place|
|Mancini hints at Shaqiri and Santon departures|
|Bojan raring to go after return from injury|
|Babel backs Firmino to shine at Liverpool|
|Falcao must wait to impress, warns Chelsea favourite|
|Bartomeu: Deal in place for Turan|
|Parejo re-signs with Valencia|
|MLS Review: Sounders return to winning ways|
|Klinsmann unhappy with USA performance|
|High hopes for Paraguay - Diaz|
|Gareca: More to come from Peru|
|Gerrard had European offers|
|Argentina out to spoil Chile´s party - Martino|
|Sampaoli: Chile won´t change style|
|Di Maria will come good at United - Rojo|
|Peru 2 Paraguay 0: Gareca´s men finish third at Copa|
|United States 4 Guatemala 0: Klinsmann´s men win comfortably|
|´I’d prefer no-one to know my name´ - Bassett|
|Matthews completes Sunderland move|
|Podolski set for Galatasaray medical|
|Gundogan inspires Dortmund victory|
|Inter confirm Montoya capture|
|Murillo joins Inter, as Kuzmanovic and Obi depart|
|Falcao signing not a risk, says former Chelsea star|
|Deeney agrees new Watford deal|
|Confidence and service the key to Falcao success at Chelsea|
|No bids for ´Chelsea target´ Baba, claim Augsburg|
|Derby swoop for Ince|
|Fiorentina consider legal action over Salah ´no-show´|
|Chelsea the team to beat in the Premier League, says Neville|
|Storari exits Juve for Cagliari|
|UEFA removes FFP restrictions on Man City and PSG|
|West Brom hope for new owners within the month|
|Chelsea agree loan deal for Falcao|
|Kuyt eyes trophies on Feyenoord return|
|Chile v Argentina: History beckons ahead of Copa America final|
|Wallace extends Monaco loan|
|Mihajlovic wants to instill fear factor at Milan|
|Mignolet improving at Liverpool - Grobbelaar|
|Mumbai City name Anelka player-manager|
|Olivia the parrot predicts Japan to win Women´s World Cup|
|Lusitans coach blasts Bilic´s ´lack of respect´|
|Sakho eyes more Europa League wins|
|Gareca wants Peru to keep building|
|Chile ´no chance´ if Argentina produce their best - Diaz|
|Ocampos joins Marseille permanently|
|Europa League Review: Cloud-nine Brondby ignite opening round|
|West Ham 3 Lusitans 0: Sakho nets twice at start of Europa League journey|
|Holebas makes Watford move|
|Milan secure Adriano signing|
|Peru v Paraguay: Diaz counts cost of semi-final loss|
|Bastia hit out at reports of extra debt|
|Hernandez has successful surgery|
|Odemwingie signs one-year Stoke extension|
|Uth signs for Hoffenheim|
|Henen seals Everton return|
|Cattermole pens long-term Sunderland deal|
|United States v Guatemala: Klinsmann backs Dempsey ahead of Gold Cup warm-up|
|West Ham working on Jenkinson return - Gold|
|Milan agree deal for Bacca|
|Real buy back Vazquez from Espanyol|
|Richards leaves Swansea for Fulham|
|McShane signs for Reading|
|Giggs tells youngsters to seize US chance|
|Hammond pens Leicester extension|
|Only Schweinsteiger can decide Bayern future - Guardiola|
|Cech plans to play until he´s 40|
|Montoya arrives in Milan ahead of Inter move|
|Hernandez out of Gold Cup|
|US asks Switzerland to extradite seven FIFA officials|
|MLS Preview: Sounders seek momentum switch|
|Mexico 0 Honduras 0: Hernandez injury sours friendly|
|Hernandez taken to hospital|
|Garay in doubt for Copa America final|
|Wambach: USA peaking for World Cup final|
|Bassett ´an absolute hero´ despite own goal - Sampson|
|Japan 2 England 1: Late own goal breaks English hearts|
|Salvo quits as Valencia president|
|Costa not Ribery cover - Bayern director Sammer|