La Liga's title race will go to the final game after Atletico Madrid were held to a 1-1 home draw against 10-man Malaga on Sunday.
Leaders Atletico were not the only side held, with the second-placed Barcelona playing out at a goalless stalemate at Elche.
Real Madrid's 2-0 defeat at Celta Vigo means that Atletico and Barcelona are the only sides who can win the title, setting up a mouth-watering clash between the duo at Camp Nou next weekend.
Atletico know that a point at Barcelona would secure them their first La Liga crown since 1996, but defeat would hand Gerardo Martino's side the title in dramatic circumstances.
David Villa – replacing the injured Diego Costa (thigh) – came closest to scoring in the first half, hitting the bar when one-on-one with Malaga goalkeeper Willy Caballero.
Atletico dominated the first hour, but were made to pay for their profligacy when Samuel Garcia gave Malaga a shock lead in the 65th minute.
Toby Alderweireld failed to deal with a long ball and as a result, Samu got in and behind the defence, lobbing the onrushing Thibaut Courtois before heading in from an angle.
Alderweireld went from zero to hero when he headed in a 74th-minute corner, but Atletico had to settle for a point, even if Malaga defender Marcos Angeleri was sent off in the dying stages, with Adrian Lopez sensationally denied by Caballero in stoppage time.
The share of the spoils secures Malaga's top-flight status, while Atletico will go into their title showdown with defending champions Barca hoping they do not rue two dropped points.
Costa was not Atletico's only absentee, with suspended defender Diego Godin replaced by Alderweireld, but the Belgium international had little to do in the first half as the hosts dominated without scoring.
Diego Simeone's side first went close in the fifth minute, when Tiago's stabbed effort went out for a corner via the arm of Eliseu.
Atletico's penalty appeals were waved away, and in truth Malaga would have been unlucky if referee Jose Teixeira pointed to the spot, given the close proximity of the defender to Tiago.
Villa's chance followed, but he could only hit the crossbar after being sent through by Raul Garcia's flick-on header.
And the hosts headed to the break frustrated after they failed to convert two excellent Juanfran crosses.
The initial chance was poked wide by Koke, who preferred to use his right foot when it seemed easier to shoot on his left, before Garcia nodded a free header wide, although he was distracted by Alderweireld going for the same ball.
Atletico's pressure kept coming after the break, as Koke dragged an effort wide before Villa was kept out by Caballero from a tight angle.
With the hosts pouring numbers forward, they were vulnerable to counter-attacks, and Simeone had Courtois to thank for his excellent save to deny Roque Santa Cruz on the hour mark.
The one-on-one chance served as a warning for Atletico, and it was one they did not heed, as Samu kept his composure to nod in the opener after lifting over Courtois.
Diego had a shot pushed wide with 18 minutes left and less than 60 seconds later, Villa was denied by Caballero after a well-worked set-piece.
Atletico's pressure eventually told, though, as Alderweireld made amends by rising highest to head a corner past Caballero and in.
The hosts could not find a winner despite Angeleri's second yellow card with three minutes left, meaning the stakes could not be higher for their trip to Barcelona.
|Pochettino wants four Tottenham signings before transfer window closes|
|Kayode loaned to Girona after joining Manchester City|
|Conte bursts out laughing over Costa´s ´criminal´ treatment claim|
|Costa: Chelsea return would not be fair situation|
|Juventus boss Allegri sees ´five or six´ teams in Scudetto race|
|Barcelona, Real Madrid hold minute´s silence for Las Ramblas victims|
|Diego Costa is not an Atletico player - Simeone unmoved on Chelsea star|
|Costa accuses Chelsea of pricing him out of Atletico Madrid move|
|Armstrong signs new Cetlic deal to end speculation|
|Serie A 2017-18: Ambitious AC Milan set sights on Juventus dominance|
|Frankfurt medical for Boateng after Las Palmas exit|
|Castro shocked by Dembele as Dortmund star pushes for Barcelona move|
|Defoe pushing for start against Watford|
|Jese Rodriguez set to make Stoke debut against Arsenal|
|West Brom don´t need to sell Evans - Pulis responds to Manchester City bid|
|Matic in Chelsea dig: Manchester United are definitely bigger|
|Serie A 2017-18: Shock signing Bonucci, Juve star Dybala - five stars to watch|
|Bilic ´sure´ Liverpool target Lanzini is staying at West Ham|
|Bailly: Manchester United will prove world-class status this season|
|Klopp: No reason to leave Liverpool as Barca eye Coutinho|
|Montella happy with Milan progress|
|United signing Matic from Chelsea a masterstroke - Robson|
|Milan in ´advanced´ talks to sign Kalinic, Fassone tight-lipped on Ibrahimovic|
|Barcelona to honour terror victims in LaLiga opener|
|Europa League Review: AC Milan on fire, Athletic Bilbao in stirring comeback and Fenerbahce suffer s|
|We were lucky - Koeman frustrated by Everton´s second-half struggle|
|Bonucci revels in ´wonderful´ San Siro bow as AC Milan destroy Shkendija|
|Everton 2 Hajduk Split 0: Keane opens account in comfortable Europa League win|
|AC Milan hit 24-year high in Shkendija thrashing|
|AC Milan 6 Shkendija 0: Silva, Montolivo inspire Rossoneri to brink of Europa League group stage|
|Messi, Ronaldo and Suarez lead tributes as football stands with Barcelona|
|Usain Bolt offered burgers and beer to join Portuguese football club|
|Hummels joins Mata in pledging one per cent of his wages to charity|
|Carroll poised for West Ham return at Newcastle|
|Arsenal´s Alexis Sanchez named in latest Chile squad|
|Ruben Yanez joins Getafe from Real Madrid|
|Clement: Swansea can be stronger without Sigurdsson|
|Paulinho insists he can fit in at Bacelona|
|Gabi urges Costa to respect Chelsea despite desire to join Atletico Madrid|
|Mbappe left out of Monaco squad amid ongoing PSG links|
|Zidane, Mourinho, Low, Conte and Guardiola to battle for Best FIFA Men´s Coach prize|
|Bosz has ´no idea´ whether Dembele will stay at Dortmund|
|Messi, Ronaldo, Iniesta and Kane among nominees for Best FIFA Men´s Player award|
|Messi not signing new deal would surprise Barcelona VP Mestre|
|Barca in ´difficult situation´ over Coutinho and Dembele|
|Sturridge fit for Palace clash|
|LaLiga 2017-18: Messi in transition, Bale battling for his place - five stars to watch|
|Nothing has changed over Coutinho - Klopp|
|Barcelona´s Luis Suarez to miss four to five weeks with knee injury|
|James one of six Bayern stars out of Bundesliga opener|
|Tottenham midfielder Sissoko: No agreement with any club|
|Barca ´not a millimetre closer´ to signing Dembele - Watzke|
|Neymar money would fund us for ´15 years´, says Toulouse boss|
|Transfer market is crazy, admits £45m Everton new boy Sigurdsson|
|Barcelona complete €40m Paulinho signing from Guangzhou|
|LaLiga 2017-18: Madrid ready to tighten grip on bumbling Barcelona|
|Brighton tie Knockaert, Dunk & Duffy to new deals|
|Milan ready to fight for Scudetto - Kaka|
|Bundesliga 2017-18: Ancelotti angst, Bosz bottle and VAR all under scrutiny as new season kicks off|
|Carvajal: Real Madrid were all over Barcelona|
|Bundesliga 2017-18: James checks in as Aubameyang stays – five stars to watch|
|Behrami leaves Watford for Udinese|
|Wenger and Arsenal willing to make financial sacrifice on Sanchez|
|Montreal Impact 3 Chicago Fire 0: Piatti double sinks slumping visitors|
|Pique: This is the first time I´ve felt inferior to Real Madrid|
|Asensio: Madrid played better and deserved Supercopa title|
|Barca star Suarez to undergo tests on knee injury|
|Barca close to signing Coutinho and Dembele - Segura|
|Valverde: Madrid aren´t invincible as Barca boss laments Neymar loss|
|Zidane lauds ´spectacular´ Madrid after Supercopa triumph|
|PSG troll Barcelona over Supercopa loss to Madrid|
|Real Madrid 2 Barcelona 0 (5-1 agg): First-half Barca failings settle Supercopa|
|Champions League Review: Mertens stars as Napoli put two past Nice|
|Rodgers eyes Liverpool reunion after ´perfect´ Celtic hammer Astana|
|Demebele can´t just do whatever he wants - Dortmund team-mate Sokratis|
|Championship Review: Norwich off the mark, Sheffield Wednesday hold Sunderland|
|Celtic 5 Astana 0: Sinclair double helps put Rodgers´ men on brink of qualification|
|Sigurdsson to Everton joins Lukaku, Torres and Sterling among biggest all-Premier League deals|
|Sigurdsson completes club-record move from Swansea to Everton|
|Izquierdo granted work permit ahead of club-record Brighton switch|
|Van Persie and Babel win Netherlands recalls|
|Ronaldo brands five-match ban ´exaggerated and ridiculous´|
|Bayern in ´good rhythm´ after poor pre-season - Ancelotti|
|Van Dijk not for sale, says Southampton chairman|
|Liverpool loan Ojo to Fulham|
|Ronaldo´s appeal against five-match ban rejected|
|PSG´s Matuidi arrives in Turin to complete Juventus switch|
|Barcelona threaten legal action over Paulinho deal allegations|
|Sigurdsson undergoes Everton medical, Koeman lavishes praise|
|Boateng leaves Las Palmas for personal reasons|
|Coutinho one of the best in the world, says Liverpool team-mate Can|
|Pulisic staying at Dortmund despite Liverpool speculation|
|Gundogan not rushing Premier League comeback|
|Carlos Bacca joins Villarreal from AC Milan|
|Wenger happy Sanchez & Oxlade-Chamberlain have not followed Coutinho path|
|Newcastle land Joselu in £5m deal|
|Jese Rodriguez joins Stoke from PSG|
|No progress on Alexis Sanchez contract, admits Arsenal boss Wenger|
|Klopp excited by ´incredible´ Alexander-Arnold after starring role in Liverpool win|
|Melbourne Victory confirm Sanchez signing|
|Aston Villa fans ´carried away´ after Terry signing, says Bruce|
|Hoffenheim had ´clearer´ chances, says Nagelsmann|
|Pogba determined to win Premier League with Man Utd|
|Championship Review: Ipswich win again in dramatic fashion|