The Western Sydney Wanderers must overturn a two-goal deficit if they are to progress to the AFC Champions League quarter-finals.
Western Sydney return to Pirtek Stadium on Wednesday trailing 3-1 on aggregate after last week's defeat to Sanfrecce Hiroshima.
Tony Popovic's men, beaten by Brisbane Roar in the A-League grand final, trailed 2-1 inside the final 12 minutes having netted the all important away goal courtesy of striker Tomi Juric.
But the Wanderers conceded a third goal in the closing stages, leaving them with an uphill battle to advance from their knockout tie against the Japanese outfit.
A 2-0 victory would be good enough for Western Sydney to book their spot in the final eight and Juric said the Australian team are planning to attack from the outset.
''We have to play attacking football next week,'' he said.
''So we're going to go out there and that's exactly what we're going to do. We want to progress to the next round.''
With the A-League season over, the Wanderers will be fresh and will take heart from the fact that they have gone six games without defeat on home soil in all competitions.
During that period, Western Sydney have scored 12 goals, while keeping five clean sheets in the process.
Sanfrecce's away record makes for good reading also, with Hajime Moriyasu's side unbeaten in their past seven games on the road, though they were beaten by the Central Coast Mariners in their most recent trip to Australia in March.
Meanwhile, defending champions Guangzhou Evergrande are practically assured of a quarter-final berth after trouncing Cerezo Osaka in the opening leg in Japan.
Marcello Lippi's Chinese giants routed Cerezo 5-1 away from home and withstanding a remarkable collapse in front of their home fans, they will progress on Tuesday.
In other fixtures, Pohang Steelers are well placed to qualify for the next round ahead of fellow South Korean outfit Jeonbuk Motors on Tuesday.
Pohang, winners in 2009, scored two away goals as they won 2-1 in Jeonju last week.
Al Ain also return home on Tuesday with a 2-1 advantage after getting the better of Al Jazira in their all-United Arab Emirates affair.
Last season's runners-up Seoul have the upper hand against Kawasaki Frontale of Japan, with the K-League giants leading 3-2 on aggregate heading into Wednesday's second leg on home soil.
Elsewhere, Al Ittihad hold a slender 1-0 lead as they make the trip to Al Shabab for the second leg in Saudi Arabia on Tuesday.
Uzbek outfit Bunyodkor have only won one of their past five games away from home in the Champions League and they must better that record if they are to get past Saudi Arabia's Al Hilal, who lead 1-0 on aggregate.
Meanwhile, the tie between Iran's Foolad and Al Sadd is evenly poised after last week's goalless draw in Qatar.
|Yedlin open to loan move|
|Tigres not scared of River trip - Ferretti|
|MLS Preview: Wright-Phillips, Lampard set to debut|
|´A draw is good for us´ - River´s Gallardo confident of Libertadores success|
|Di Maria poised for PSG switch - Blanc|
|Franjic: Bring on Bangladesh, Tajikistan|
|Van Gaal bemoans De Gea situation|
|MLS All-Stars 2 Tottenham 1: Kane stunner can´t spare Spurs|
|Manchester United 0 Paris Saint-Germain 2: Van Gaal´s defensive frailties exposed|
|Tigres UANL 0 River Plate 0: Visitors lose Gallardo in Copa Libertadores final first leg|
|Penedo parts ways with Galaxy|
|Benitez backs Mihajlovic, Milan to succeed|
|Barnetta joins Union in MLS|
|Allegri critical of Morata´s attitude|
|Franjic targets more A-League glory with City|
|Beto undaunted by Super Cup clash against Barca|
|Advocaat upbeat despite another Sunderland flop|
|McClaren praises Newcastle recruit Mitrovic|
|Payet will improve West Ham - Bilic|
|Pulis confirms interest in Lambert|
|Deila expects tough test in Baku|
|Drogba mobbed by Montreal Impact fans|
|UEFA Champions League Review: Ajax spurn two-goal lead at 10-man Rapid|
|Sunderland´s struggles continue as Doncaster cruise to win|
|Mahrez and Nugent on target in Leicester win|
|Mitrovic tastes debut defeat for Newcastle|
|Celtic 1 Qarabag 0: Boyata snatches crucial win|
|Jablonec 0 Copenhagen 1: Verbic cracker gives Danes the edge|
|Norwich sign Wisdom on loan from Liverpool|
|UEFA Europa League Preview: Koeman plays down importance of Vitesse links|
|Schneiderlin keen to learn from experienced duo|
|Mandzukic´s maiden Juventus goal seals win in Poland|
|Fofana completes Bastia loan|
|Deila delighted that Gordon pledges future to Celtic|
|Grenier ruled out for four months|
|Rooney: United squad ready for title challenge|
|Messi and Neymar available for start of season|
|Szczesny seals Roma switch|
|Benitez cools Mourinho war of words|
|Filipe Luis vows to win back Atletico fans|
|Besiktas in negotiations over Gomez switch|
|Kishna seals Lazio switch|
|Diaby completes Marseille move|
|Platini is bad for FIFA - Prince Ali|
|Bilic keen to make further additions|
|Brady makes Norwich move|
|Southampton complete Caulker loan|
|Rummenigge feels Muller ´will never leave´ Bayern|
|Platini to stand in FIFA presidential election|
|Howedes to remain Schalke skipper|
|Albion sign Hull defender Chester|
|Lucescu defends Fred selection amid doping allegations|
|Fabregas still in love with Arsenal|
|Luis Enrique ´happy´ with Barca´s US trip|
|Mourinho optimistic over Cahill and Costa|
|River owe Tigres´ Esqueda - Mercado|
|Van Gaal expecting big season from Shaw|
|Begovic keen to challenge Courtois|
|Mourinho launches attack on Benitez|
|CONMEBOL ´knocked on a lot of doors´ to keep half-spot - president|
|America 0 Benfica 0 (3-4 on penalties): Primeira Liga champions finally win|
|Napoli striker Higuain ´untouchable´ - Gabbiadini|
|Arsenal´s friendly form will boost confidence - Wenger|
|Nagatomo-Melo swap possible, says agent|
|Chelsea 2 Barcelona 2 (4-2 on penalties): Courtois stars for Premier League champions|
|Eriksen calls for ruthless Spurs|
|Pulis praises Berahino attitude|
|Alderweireld confident of top-four finish|
|Villa ready for tough Spurs clash|
|West Ham edge win on Carrow Road anniversary|
|Kozak scores twice as Villa draw at Wolves|
|Stanislas brace leads Bournemouth past Yeovil|
|Watford slip to friendly defeat at Cardiff|
|Lukaku injury sours Everton win at Dundee|
|UEFA Champions League Review: Fenerbahce draw blank as Monaco impress|
|West Brom earn friendly win over Walsall|
|Vardy at the double as Leicester beat Burton|
|Atletico impress in win over Oviedo|
|Herrera sacked by Mexico after ´punch´|
|Gerrard, Keane and Bradley pull out of MLS All-Star squad|
|Marseille reach Diaby agreement|
|Sammer thrilled with Vidal´s winning mentality|
|Platini expected to launch FIFA presidency bid|
|Romanov sacked me over Barca snub - Korobochka|
|Villa complete Crespo capture|
|Wolfsberger v Borussia Dortmund: Bender praises ´fun but exhausting´ training|
|Okaka swaps Sampdoria for Anderlecht|
|Southampton v Vitesse: Fonte excited for ´dream´ sojourn into Europe|
|Bournemouth agree King compensation|
|West Ham v Astra: Kouyate confident West Ham can progress|
|Vidal completes Bayern switch, signs four-year deal|
|Fabregas calls for Champions League improvement|
|BREAKING NEWS: Filipe Luis completes Atletico return|
|Bayern to present Vidal|
|Wenger unfazed by Mourinho´s spending jibe|
|Pellegrini: Sterling will justify price tag|
|Cavani hit with two-match Uruguay ban|
|Bonucci to remain at Juve until 2020|
|No bids for Berahino - West Brom|
|Putin: Blatter deserves a Nobel prize|
|Howe: Swansea a benchmark for Bournemouth|
|New Parma to play in Serie D|
|Mata vows to hit the goal trail at United|
|Drogba ´perfect fit´ for Montreal|
|Berahino ´not yet´ ready for Tottenham - Irvine|
|Romero lauds caring Van Gaal|
|Jese flying at Real under Rafa|
|Sampdoria unwilling to pay €10m for Balotelli|
|Mourinho talks up Arsenal title chances|
|Hull sign Ryan Taylor, Sam Clucas|
|Kane, Pochettino hail MLS All-Star test|
|Di Santo sorry for swift Werder departure|