Juventus face the toughest possible penultimate hurdle in their bid to become Serie A's first centurions this weekend.
Antonio Conte's team, fresh from securing a third successive Scudetto, require a draw at second-placed Roma to tie Inter's record points haul of 97 for a season - set in 2007 - before they round off their campaign at home to Cagliari next week.
Victory at Stadio Olimpico would keep Juve on course for the 100-point mark, but Roma - who have racked up 85 points from their 36 fixtures so far this term - are undefeated at home this season.
Juve have also lost 1-0 on their last two visits to face Roma, but will take heart from the fact they won the reverse game 3-0 back in January.
With the top three positions already settled - Napoli, who travel to out-of-form Sampdoria on Sunday, are assured of finishing third - attention can turn to the battle for UEFA Europa League qualification.
Fiorentina, who visit bottom-placed Livorno, are all but certain to end the season in fourth, meaning Inter, Torino, Parma, Milan, Verona and Lazio are fighting it out for two Europa League spots.
And two matches this weekend will have a big say on who qualifies for continental competition.
The outstanding form of winger Alessio Cerci and Ciro Immobile - Serie A's leading scorer - have helped sixth-placed Torino take 16 points from their last six games, and victory at home to Parma could secure the Turin outfit European football for the first time in 20 years.
Meanwhile, Lazio are the guests at Inter legend Javier Zanetti's San Siro swansong on Saturday.
The 40-year-old, who joined Inter almost two decades ago, this week announced he is to retire at the end of the season and the club will honour him before and after their last home game of the campaign.
Fifth-placed Inter have lost their last four matches against Lazio, who sit just four points behind them in 10th, and go into the game on the back of a derby defeat to rivals Milan last week.
Milan, who are eighth in the table, go in search of a seventh Serie A win in eight matches at mid-table Atalanta, while while ninth-placed Verona host Udinese.
At the wrong end of the league, Sassuolo, Chievo, Bologna, Catania and Livorno are embroiled in a scrap to avoid the three relegation places.
The fate of basement club Livorno, who have taken just one point from their previous eight games, will be sealed if they fail to beat Fiorentina.
Sassuolo, in 16th, require victory over visiting Genoa to secure survival, while Bologna host Catania - in 18th and 19th - in a showdown both sides simply have to win, and Chievo travel to Cagliari.
|16||D. De Rossi|
|Coach: R. Garcia|
for D. De Rossi 55'
for M. Benatia 71'
for M. Destro 80'
|Roberto happy to play full-back for Barca|
|Gestede eager to make his mark at Villa|
|I want to play more and score more - Remy|
|Lambert influence important, says Pulis|
|Benteke a ´bargain´ buy - Rodgers|
|Zola: Qatar would be ideal for Balotelli, Cassano|
|Suarez: I´m not among world´s best|
|PSG ready despite ´chaotic´ pre-season - Blanc|
|Arsenal thumping still hurts - Fournier|
|Aubameyang targets Champions League success|
|Rooney set for Everton return|
|Cech can match Van der Sar - Wenger|
|Mourinho ponders Wenger´s losing record against him|
|CBF confirm Fred failed a doping test|
|Bournemouth beaten by battling Cardiff|
|Immobile injury overshadows Sevilla win at Vicarage Road|
|Lambert at the double on West Brom bow|
|Real sign up Spain starlet Vallejo|
|Valencia blow for West Ham|
|Elche cleared to play in Segunda Division|
|Baker pens a new Villa deal|
|Lambert makes Albion switch|
|Gillingham and Scally found guilty of ´race victimisation´|
|Inter complete Jovetic signing|
|Arsenal v Chelsea: Mourinho cools Wenger rivalry ahead of Wembley meeting|
|Villa snap up Gestede|
|Villa land Veretout|
|Mourinho coy on fresh Stones bid|
|Aubameyang commits to Dortmund|
|Torres on the hunt for trophies with Atletico|
|Cazorla and Walcott sign new Arsenal deals|
|Quick start vital in Arsenal title bid - Wilshere|
|I have received no offers - Guardiola|
|Barcelona to monitor Turan injury|
|Zorc ´surprised´ by Grosskreutz-Tuchel row|
|Phil Neville could be England manager - Moyes|
|UEFA to investigate Shakhtar´s Fred selection|
|City loan Unal to Genk|
|China v South Korea: Stielike looking for new options|
|North Korea v Japan: Halilhodzic to unearth new faces|
|Drogba: I want to be ready, not a burden|
|Hamstrung Clasie in doubt for Southampton league opener|
|West Ham goalscorer Zarate bemoans Astra comeback|
|Negredo quashes Valencia exit rumours|
|´This is not my Sampdoria´ - president Ferrero|
|Criscito could join Inter - agent|
|CBF endorse Zico´s FIFA presidency campaign|
|Hawit to handle CONCACAF´s referee review|
|Falcao is a ´top, top player´ - Terry|
|Tuchel pleased by Dortmund fighting qualities|
|Premier League rules out schedule changes for Champions League clubs|
|UEFA Europa League Review: Southampton stroll as Sampdoria are humiliated|
|Koeman confident of Southampton progress|
|Bilic frustrated with Collins´ red card, Valencia injury|
|Bamford hits hat-trick in Bromley friendly|
|Southampton 3 Vitesse 0: Play-offs in sight for Koeman’s men|
|Wolfsberger 0 Borussia Dortmund 1: Tuchel begins tenure with narrow win|
|West Ham 2 Astra 2: Collins red allows visitors back in|
|Kukesi - Legia match abandoned|
|Joining Roma an ´easy decision´ - Szczesny|
|Chiriches joins Napoli from Spurs|
|Mihajlovic pleased with Milan improvements|
|Injured Chiellini to miss Supercoppa|
|Newcastle complete Mbemba swoop|
|Blackpool protest incurs FA fine|
|Scottish Premiership Preview: Dons seek to run Celtic closer|
|Paris Saint-Germain v Lyon: Ibrahimovic ready for season opener|
|Wolfsburg v Bayern Munich: De Bruyne centre of attention|
|Real Madrid 0 Milan 0 (10-9 on pens): Real lift second International Champions Cup|
|De Bruyne a doubt for Supercup clash|
|Reine-Adelaide needs time to blossom, says Walcott|
|Rodgers will not rush Ibe development|
|Napoli not interested in selling Higuain - De Laurentiis|
|Wilson agrees Bournemouth extension|
|Messi makes early Barcelona return|
|Ibrahimovic: My next move will be a very big surprise|
|Van Aanholt backs Lens to shine|
|Besiktas complete loan move for Gomez|
|McClaren: No decision on Coloccini future|
|Kane, Kaka hail goalkeeper Rimando|
|Chung eager to become FIFA president|
|Yedlin open to loan move|
|Tigres not scared of River trip - Ferretti|
|MLS Preview: Wright-Phillips, Lampard set to debut|
|´A draw is good for us´ - River´s Gallardo confident of Libertadores success|
|Di Maria poised for PSG switch - Blanc|
|Franjic: Bring on Bangladesh, Tajikistan|
|Van Gaal bemoans De Gea situation|
|MLS All-Stars 2 Tottenham 1: Kane stunner can´t spare Spurs|
|Manchester United 0 Paris Saint-Germain 2: Van Gaal´s defensive frailties exposed|
|Tigres UANL 0 River Plate 0: Visitors lose Gallardo in Copa Libertadores final first leg|
|Penedo parts ways with Galaxy|
|Benitez backs Mihajlovic, Milan to succeed|
|Barnetta joins Union in MLS|
|Allegri critical of Morata´s attitude|
|Franjic targets more A-League glory with City|
|Beto undaunted by Super Cup clash against Barca|
|Advocaat upbeat despite another Sunderland flop|
|McClaren praises Newcastle recruit Mitrovic|
|Payet will improve West Ham - Bilic|
|Pulis confirms interest in Lambert|
|Deila expects tough test in Baku|
|Drogba mobbed by Montreal Impact fans|