Victory for Atletico Madrid against Malaga on Sunday could see them crowned La Liga champions for the first time since 1996.
If Atleti bounce back from their defeat to Levante and Barcelona fail to beat Elche, Diego Simeone's men will have brought a conclusion to one of the most enthralling title races Spain has seen for many years.
A Filipe Luis own goal coupled with David Barral's late effort condemned Atleti to a first La Liga defeat in 11 matches but Simeone's charges were spared slightly by the fact that Barcelona and Real Madrid both dropped points.
Regardless, Simeone will be hopeful of a better showing against Malaga in their final game of the season at the Vicente Calderon.
Malaga, five points clear of the drop, have work to do to make certain their safety and Atleti will hope to do their bit while praying for a Barca defeat - ahead of their potentially decisive trip to Camp Nou on the final day.
However, defender Juanfran has warned against taking Malaga lightly and says the squad are not thinking of the Barcelona match or its likely importance.
"If we win both of the remaining fixtures we'll be champions and the first one is against Malaga," he said. "But it would be an error to think beyond Malaga.
"The team is doing perfectly. If you work, work, work, you'll be rewarded and we've worked as hard as anyone."
Atleti won the reverse fixture 1-0 in January and have lost just one of their last seven meetings with Malaga.
Sunday's hosts will be confident of extending that strong run with Bernd Schuster's charges having won just one of their last four while failing to score in their last two outings.
Malaga's hopes may be boosted by the potential absence of Diego Costa (thigh), but goalkeeper Willy Caballero has urged his team-mates to simply focus on ending the season well.
The former Elche stopper has "no interest" in the title race and instead wants to secure the win that will keep them safe.
"With regards to my opinion on the league, my only concern is fighting for my club and to ensure our place in the elite next season," he said.
"Nothing else interests me right now. We need to remain cautious and fight and defend well.
"I have no interest in who wins the league this year."
|Coach: D. Simeone|
for Koke 57'
for Raúl García 63'
for A. Turan 70'
|Genk part company with Ferrera after just one game of season|
|Gold clarifies Twitter gaffe|
|Vidic adapting to different style at Inter|
|Toulouse bring in Matheus|
|Butragueno backs Rodriguez to cope with pressure|
|Benteke aiming to come back stronger|
|Valdez joins Frankfurt|
|Jovetic ready to shine|
|Simeone hails Griezmann qualities|
|Monk unsure over De Guzman future|
|Benitez: Michu will take time to adjust|
|Diaby confident of staying fit|
|Shaw not fit enough, says Van Gaal|
|MLS Preview: RSL look for attacking spark|
|Monk slaps ´astronomical´ price on Bony´s head|
|Australian clubs looking at Ronaldinho|
|Sinclair enjoying ´one of the best pre-seasons´|
|Spiranovic surgery a success|
|Seattle Sounders 0 Los Angeles Galaxy 3: First-half blitz fires Californians to victory|
|Lemina thrilled with Bielsa effect|
|Bayern´s Green chomping at the bit|
|Palace complete US tour with easy win|
|Carragher: Liverpool didn´t want me|
|Simeone: Atleti´s La Liga triumph was no fluke|
|Sturridge: ´I´ll step up´|
|Van Gaal: Formation gives United flexibility|
|Mathieu insists age is no barrier|
|Martinez the deal sealer, says Besic|
|Coaches embrace blockbuster Serie A start|
|Ronaldinho to leave Atletico Mineiro|
|Lorient capture Ayew|
|Celtic loan Berget, sell Watt|
|Pires signs up for Indian Super League|
|Allegri set for early San Siro reunion in maiden Juve campaign|
|Bakayoko makes Monaco move|
|Bakayoko makes Monaco move|
|Lens granted Ligue 1 place|
|UEFA Champions League Preview: Red-hot Salzburg face Qarabag|
|Parma bring in Cassani from Fiorentina|
|De Vrij set for Lazio|
|BREAKING NEWS: Everton complete Besic signing|
|Kongolo pens Feyenoord extension|
|Redknapp confirms Granero exit|
|Advocaat confirmed as Serbia coach|
|CSL Preview: Henan aim to escape drop zone, Liaoning host Guangzhou RandF|
|Arribas makes Sevilla switch|
|Chambers joins Arsenal|
|Ospina buoyed by Arsenal recruitment|
|Liverpool´s loss is our gain, says Redknapp on Remy|
|Ferdinand: I would still be at United with Giggs in charge|
|Pepe targets Super Cup glory|
|Martinez prioritising striker signing|
|Perez not looking to leave Benfica|
|Klopp itching to work with full Dortmund squad|
|Mourinho: It feels like Drogba never left|
|FIFA asks for FIGC review into alleged racist remark|
|Hull to review Maguire deal|
|Wenger prepared to gamble on Chambers|
|Atletico agree Griezmann deal|
|Irvine planning further striker addition|
|Campbell: Black professionals scared to talk about racism|
|Mata backs Herrera to star in Premier League|
|Injured Rafael returning to Manchester|
|Schmidt demands more from Leverkusen|
|Copa Libertadores Preview: Defensor Sporting banking on home record|
|Remy´s Liverpool move off, confirms Rodgers|
|Inzaghi demands nastiness from Milan|
|MLS Review: Timbers triumph in Montreal, Dallas thwart Vancouver|
|Jovetic ready to lead City line - Pellegrini|
|Lewandowski impresses Ribery, Alaba|
|Colombian Primera A Review: Three clubs remain perfect, Atletico Nacional get off the mark|
|Rodgers: ´We can score goals´ without Suarez|
|Chilean Primera Division Review: Canales brace powers Universidad Chile|
|Atletico Madrid need penalties to edge past Earthquakes|
|Liga MX Review: Monterrey, America stay perfect|
|Paraguayan Primera Division Review: Capiata set pace|
|Brazilian Serie A Review: Cruzeiro win again, Kaka scores|
|Sterling goal sees Liverpool past Olympiacos|
|Peruvian Primera Division Review: Los Caimanes notch maiden win, Inti Gas claim top spot|
|CAF Champions League Review: Zamalek held, Vita Club leave it late|
|Jovetic at the double as Manchester City thrash Milan|
|Monk thrilled by Sigurdsson contribution|
|Lovren signs for Liverpool|
|Mourinho pleased with Olimpija test|
|Vertonghen eager to remain at Spurs|
|Sigurdsson marks Swansea return with a brace|
|Lewandowski, Rode help Bayern retain Telekom Cup|
|Immobile scores and suffers injury in Dortmund win|
|Costa scores on Chelsea debut|
|CAF Confederation Cup Review: Leopards de Dolisie 1 Real Bamako 2|
|Thai Premier League Review: Buriram pull clear, Police edge away from danger|
|Falcao nears Monaco return|
|CSL Review: Harbin Yiteng produce another upset, Evergrande stretch lead|
|Britton and Emnes to miss season-opener|
|Taylor-Fletcher strike sinks Everton|
|J.League Review: Chasing pack close on Urawa Reds, Tokushima Vortis secure rare win|
|Ancelotti expects fresh Bale to be even better|
|Simeone keen on Griezmann|
|Mazzarri refuses to set Inter targets|
|Lazio director targeted by fans|
|Dyche rules out Deeney move|
|Rummenigge: Bayern will never sack Guardiola|
|BREAKING NEWS: Arsenal to bring in Ospina|
|Pochettino quiet on Schneiderlin link|
|Vidic settling into Inter life|
|Van Gaal hints at Zaha United future|
|Di Maria will report for training - Ancelotti|
|Wilshere vows to answer critics|
|Rodgers expecting titles|
|Deila demands Celtic cutting edge|
|Rodgers: We won´t rush Lallana|
|Wenger: We have to be better against top-level teams|
|FIGC presidential candidate uses racist slur|
|MLS Review: Columbus claim second straight win, Toronto falter|
|Villa battle past Dynamo in Houston|
|United more efficient, says Garcia|
|Pedestrian Tottenham edge past Chicago Fire|
|Van Gaal bemoans display|
|CS Sfaxien 1 ES Tunis 0: Troussier era opens with a win|
|Icardi stars from the spot as Inter overcome Real Madrid|
|Arsenal upstaged by Red Bulls|
|Pre-Season Friendly Review: Rooney stars for United, Bayern reach Telekom final|
|In-form Rooney inspires Manchester United win|