Atletico Madrid and Real Madrid slipped up in search of pivotal wins on a dramatic day in La Liga's title race.
Following Barcelona's surprise 2-2 draw against Getafe on Saturday, the capital clubs had the chance to all but end the defending champions' ambitions.
But Diego Simeone’s team passed up the chance to open a six-point advantage as they slumped to a 2-0 defeat on the road at bogey club Levante.
Real could not capitalise on this double slice of fortune in the late kick-off and needed a brilliant equaliser from Cristiano Ronaldo in stoppage time to hold Valencia to a 2-2 draw at the Bernabeu.
Atletico found themselves behind early on when Filipe Luis diverted a corner into his own net.
Mohamed Sissoko and Diego Costa were perhaps lucky to stay on the pitch just after the half-hour.
Referee Jose Gonzalez took no action despite the Atletico forward appearing to push his head into the Mali international, who then raised his hands to Costa’s face.
Levante defended resolutely and were rewarded in the 68th minute when David Barral finished clinically on the counter-attack.
The game ended in regrettable circumstances. Levante's Papakouli Diop became involved in a heated exchange with a section of Atletico's fans and later accused them of making racist chants towards him.
Real kicked off in the knowledge that wins in their remaining four games would be enough to take the championship, but Valencia had not read that script.
Goals from Jeremy Mathieu and former Real youth product Daniel Parejo either side of Sergio Ramos' equaliser looked to have handed Juan Antonio Pizzi's side a famous triumph.
Visiting goalkeeper Diego Alves was magnificent throughout, routinely thwarting Cristiano Ronaldo, but the Portuguese finally got the better of him in stoppage time to earn a point.
At conclusion of a tumultuous day, Atletico appear best placed, knowing victory in their last two outings will see them crowned champions. The last of those matches is the highly anticipated season-closer at Camp Nou, where Real must now hope fierce enemies Barca do them a huge favour.
At the other end of the table, Ramon Azeez's last minute header moved 10-man Almeria out of the bottom three as they secured a priceless 3-2 win over relegated Real Betis.
The game exploded into after an eventful but goalless first-half when Oscar Diaz converted Aleix Vidal's cross in the 52nd minute.
Shortly afterwards, Almeria’s on-loan Liverpool midfielder Suso was given a straight red for bringing down Damien Perquis and Braian Rodriguez levelled from close range for Betis with an hour played.
Substitute Salva Sevilla drilled into the bottom corner to put the hosts in front before Vidal netted an equaliser and Azeez lit up a the thrilling climax that brought fans streaming onto the pitch amid jubilant scenes at the final whistle.
Elsewhere, Villarreal played out a goalless draw against UEFA Europa League finalists Sevilla - limiting their own chances of qualifying for next season's competition.
|7||David Barral||60' 69'|
|Coach: Joaquín Caparrós|
for M. Sissoko 59'
for Rubén García 71'
for David Barral 80'
|Lippi named China boss after Guangzhou cancel contract|
|Simeone expects title challenge from Sevilla|
|Special quality makes Messi better than Ronaldo - Tite|
|Zidane reassures Morata: This is a marathon|
|Ronaldo made himself - Ferguson|
|A-League Review: Victory and Roar get first wins|
|Blind hits back at Spalletti in Strootman row|
|Mourinho has not lost his magic, insists Mikel|
|Suarez open to Ajax return|
|Young: There is more to come from Pogba|
|Digne at home in Barcelona and ready to help win trophies|
|Defoe´s finishing is ´absurd´ - Bilic|
|Stekelenburg grounded despite penalty heroics|
|Thiago Silva can be our Pirlo - Juve CEO hints at move for PSG defender|
|Koscielny calls for ´tough´ Arsenal|
|Birthday boy Wenger: Result will determine celebrations|
|MLS fines Drogba for Impact snub|
|Klopp backs Sturridge to bounce back|
|Conte: Chelsea still scarred from last season|
|Giggs: United decline was not inevitable|
|Falcao nets as brilliant Monaco hit Montpellier for six|
|Guardiola pleads patience for injury ravaged Kompany|
|No hard feelings as Mourinho focuses on Chelsea task|
|Guardiola: I don´t want City to play like Barcelona|
|Valencia fans´ Alcacer anger normal - Luis Enrique|
|Neymar: Playing for Barca is easy now|
|EPFL terminates agreement with UEFA|
|Aguero keeps Argentina spot, Messi returns|
|Donnarumma eyes Milan captaincy|
|Napoli fans banned from Juve trip|
|Mertesacker hails ´hungry´ hat-trick hero Ozil|
|Suarez says Barcelona renewal talks ´really advanced´|
|Lack of European football can aid Liverpool´s title bid - Pulis|
|European breaks do not benefit Chelsea - Conte|
|Pardew backs Leicester to ´come through´ tough start|
|Pochettino one of ´the very best´ coaches, says Howe|
|Puel backs Manchester City for Premier League title|
|Abramovich and I were not friends - Mourinho|
|It was not mutual consent, I was sacked by Chelsea - Mourinho|
|Brazil recall Douglas Costa, Marcelo and Casemiro for Argentina clash|
|Luis Enrique: If Messi is at his best, nobody knows how to stop him|
|Ramos deserves more than he earns - Perez|
|Neymar renewal proves Barcelona team spirit, says Luis Enrique|
|Bravo mistakes will be on the front page - Guardiola|
|I would sign Modric as Scholes´ successor - Giggs|
|At last! Neymar signs new Barcelona contract|
|Ronaldo injury helped Portugal to Euro 2016 success, says Abidal|
|Ronaldo injury helped Portugal to Euro 2016 success, says Abidal|
|Rummenigge blasts Premier League clubs for ´kidnapping´|
|Prandelli awed by Messi but ´dreaming big´ against Barcelona|
|Guardiola fumes at Aguero rumours after Barcelona omission|
|Conte: Mourinho deserves maximum respect|
|Moses happy for Conte chance after Mourinho struggle|
|Garcia dreaming of glory with lowly Marseille|
|Dawson back as Phelan expects Hull reaction|
|Conte declares Terry fit to face Mourinho´s United|
|Pardew: Why would I leave Palace for England?|
|Montella wants San Siro to strike fear into Juventus|
|Guardiola criticism ´political´, says Del Bosque|
|Ancelotti ready to unleash rampant Robben once more|
|Chelsea in a good position - Mourinho|
|Tuchel heartened by Reus return|
|Allegri wary of AC Milan after Inter ´whack´|
|Koeman hopes for Barkley ´wake-up call´|
|Melbourne City 2 Perth Glory 3: Keogh hat-tricks decider thriller|
|Dybala delighted to stay at Juve after rejected offer|
|Hughes eager to test Hull fragility|
|Carrasco extends Atletico contract|
|Moyes: I am under pressure - just like Guardiola|
|Wenger talks up Arsenal´s title credentials|
|Fuchs signs new Leicester contract|
|Guardiola doesn´t communicate - Benatia|
|Magical Messi from another planet, says awestruck Digne|
|Wenger pleased to see Ozil on goal trail as talks continue|
|Evra hails old rival Suarez as ´the best number 9´|
|Ranieri: I feel like a hybrid car|
|Falcao returns for Monaco|
|De Bruyne defends Guardiola tactics|
|Del Bosque: I rejected €10m offer from China|
|CONCACAF Champions League Review: Pumas, Dallas reach QFs|
|Alli like ´wild horse´ - Pochettino|
|Nani hails ´special´ Messi|
|Serious knee injury sidelines Hull´s Odubajo for six months|
|Mkhitaryan edging closer to comeback - Mourinho|
|Klopp: United game good prep for West Brom|
|Pogba praises Rooney after resounding win|
|Under-fire De Boer driven by reaching knockout stages|
|Pogba no longer Premier League´s ´worst´ player, mocks Mourinho|
|Austria Vienna spoil Totti milestone|
|Manchester United 4 Fenerbahce 1: Van Persie nets on return as Pogba stars|
|Puel rues unfortunate Inter defeat|
|Inter 1 Southampton 0: Candreva seals fortunate win for Inter|
|Buffon rules out club management after retirement|
|Mazzarri ´very happy´ about Holebas-Capoue row|
|Non-European city could host Champions League final - UEFA|
|Bradley calls for players to reconnect with fans|
|Pochettino lauds ´fantastic´ Howe|
|Frankfurt´s Russ eyeing return after tumour disease all-clear|
|Karanka insists Middlesbrough will not sit back against Arsenal|
|Atletico Madrid cannot sign players in January after FIFA deal|
|Koeman calls for greater Lukaku support|
|Suarez: Two goals at the Bernabeu were my best|
|Pochettino delivers mixed news on injury front|
|Karius has Klopp´s confidence|
|Suarez hopes to finish his career at Barcelona|
|Burnley suffer Defour injury blow|
|Marseille confirm Garcia appointment|
|No concerns for Ranieri as Vardy, Morgan and King miss training|
|Tony Pulis is Tony Pulis - Klopp not expecting surprises from West Brom|
|Garcia´s Roma contract terminated amid Marseille reports|
|Injured Pique ruled out for three weeks|
|Moyes the builder will fix Sunderland, says chief exec Bain|
|Walcott impressed by the ´new, aggressive´ Ozil|
|Bilic eyes Ayew injury boost|
|Bonaventura on Icardi saga: I´ll wait until I´ve won something before writing a book!|
|Van Persie: I may still be at Man Utd if Ferguson was in charge|
|Emery wants more from PSG despite victory|
|Muller: Bayern enjoyed PSV rout|
|Barcelona lose Alba and Pique to injury|
|Nolito: Messi made the difference|
|CONCACAF Champions League Review: Pachuca edge through, Timbers out|
|Ozil has ´taste´ for goals - Wenger|
|Renard, Morocco prepared for AFCON test|
|Guardiola: Barca loss not my worst|
|Luis Enrique hails ´decisive´ Messi|
|Pulisic, Green & Morris´ youth movement delight USMNT legend Jones|
|Clinical Barca point the way for Sterling and City|
|Sarri: Napoli making life hard for ourselves|
|That´s life for goalkeepers - Ter Stegen on Bravo woe|
|Schubert delighted with mature Gladbach display|
|Gunes not getting carried away after Besiktas upset Napoli|
|Lucas praises PSG response to stuttering start|
|Luis Enrique happy to rule in game of errors|
|Vitoria: Benfica face three more finals|