West Ham beat Tottenham 2-0 on Saturday to make it three wins from three against their London rivals this term and end any relegation fears.
Sam Allardyce's men won twice at White Hart Lane earlier this season, in the Premier League and League Cup, and were dominant for large spells on this occasion against a Spurs side reduced to 10 men during the first half.
After a reasonably open start to proceedings, Younes Kaboul was sent off after 25 minutes for bringing down Stewart Downing as the winger bore down on goal.
Things got worse for Tim Sherwood when an Andy Carroll header deflected in off Harry Kane just two minutes later and, on the stroke of half-time, Downing scored his first goal for West Ham with a free-kick from the edge of the area.
The result dents sixth-placed Spurs' hopes of securing UEFA Europa League football for next season.
West Ham, meanwhile, are guaranteed another campaign in the top flight, with a first win in five providing a welcome boost to manager Allardyce, who has been the subject of regular criticism from his own fans of late.
Carroll caused the visiting defence problems early on but it was Emmanuel Adebayor at the other end who should have opened the scoring.
After Christian Eriksen cleverly played him in, the Spurs forward side-footed a tame effort straight at Adrian.
Guy Demel almost profited from Carroll's aerial presence to strike the crossbar with a mis-hit strike on the turn.
Spurs then appeared to have little reason for complaint as Kaboul bundled over Downing just outside the area and was sent off.
Carroll's free-kick forced Hugo Lloris to make a smart stop and the England international helped open the scoring from the resulting corner, with his header clipping Kane and looping over Tottenham's goalkeeper to cap off a woeful few minutes for the visitors.
West Ham piled on the pressure for the remainder of the half and another foul on the edge of the box led to their second goal.
Mark Noble was brought down by Michael Dawson before Downing converted the free-kick, with Lloris likely to be disappointed with the lack of protection offered by his wall.
Mohamed Diame found the target with an overhead kick shortly after the break, while Nolan was also thwarted by a busy Lloris.
The introduction of Roberto Soldado and Sandro had little effect as Tottenham struggled to find a way back into the game, with the former spurning two half-chances.
Adrian made a fine save to deny Danny Rose in injury time, but West Ham were all but assured of victory by then and Sherwood's men could now find themselves pipped to the final Europa League place by Manchester United.
|Coach: S. Allardyce|
for A. Carroll 84'
for K. Nolan 88'
|Ajax claim Napoli keen on Milik to replace Higuain|
|Totti labels Higuain´s Juventus move ´a disaster´|
|Juventus confirm Higuain deal|
|Pato to Villarreal ´in the final stage´|
|PSG sign Lo Celso|
|Muller: Beating Dortmund will be more fun this season|
|Juventus sign Higuain from Napoli for €90m|
|Pastore: I´m like God in Paris|
|Injured Lanzini out of Olympics|
|Allegri unperturbed by Higuain fee|
|Menezes replaces Bento at Cruzeiro|
|Sporting rejected major bids from Inter and Liverpool for Joao Mario, claims father|
|Pochettino pleased by Tottenham despite Juventus defeat|
|Eriksson: Allardyce the right man for England|
|Mourinho makes United train after stepping off plane from China|
|Hazard can still match Messi, says Pedro|
|Pjanic shows there is life at Juve, with or without Pogba|
|Juventus 2 Tottenham 1: Benatia bags win for Serie A champions|
|Dembele: I am not the Bundesliga´s next superstar|
|Lyon claim €35m Arsenal offer for Lacazette rejected|
|Donnarumma dreaming of Milan captaincy as he eyes long-term stay|
|Robson: Ibrahimovic can match Van Persie´s first year at United|
|Rooney should remain England captain - Eriksson|
|Emery wants new striker at PSG|
|Santos accept Juventus bid for Gabriel|
|Eriksson expects Sweden to try and tempt Ibrahimovic out of retirement|
|Spurs signing Janssen almost quit|
|Leicester stay best for Mahrez - Ranieri|
|Allardyce to take Mourinho cue on Rooney|
|Ings ready to outdo big-money signings|
|Henderson optimistic over Liverpool campaign|
|Allardyce hardened to the challenge of England post|
|Barcelona announce record revenues for 2015-16|
|Moyes enjoys Sunderland win as Palace beat Colchester|
|Stoke complete Allen signing|
|Roma coach Spalletti warns suitors off Manolas|
|Cresswell out for up to four months with knee injury|
|Burnley fan banned by club for racist abuse|
|Dad won´t let me play at the Olympics - Larsson Sr pulls rank|
|Kostic joins Hamburg on five-year deal|
|Tevez: I´d turn down Chelsea and Napoli to stay at Boca|
|Mayoral inspired by Benzema for Wolfsburg stint|
|Allardyce straight into competitive action with England|
|Liverpool, Sevilla fined for Europa League final incidents|
|Barcelona seal Guillemenot signing as part of new Servette deal|
|Niersbach handed one-year ban over World Cup corruption|
|Chelsea and Everton ´still interested´ as Koulibaly eyes Napoli exit|
|´Still working hard´ - Balotelli trains with Liverpool kids|
|Winter breaks, long-ball football and the World Cup: Allardyce in his own words|
|Inter warn Napoli Icardi is not for sale|
|Zanetti wants Simeone back at Inter|
|Stoke snap up Sobhi|
|PSG tougher under Emery - Lucas Moura|
|Totti not ready for retirement - Pallotta|
|Confident Allardyce reveals plan for England success|
|Pochettino to discard three Tottenham players|
|Allardyce: Rooney must wait for captaincy decision|
|Aubameyang: I will only leave Dortmund for Real Madrid|
|Allegri silences questions on Pogba|
|Bruce stands by decision to quit Hull City|
|Pochettino: Not the right time for Argentina job|
|Inter yet to approach De Boer with Mancini exit rumoured|
|Ancelotti trusts me more than Guardiola - Ribery|
|Wijnaldum rejected Everton for Klopp|
|Pre-season Manchester derby cancelled|
|Coutinho excited by ´fast´ Liverpool recruits|
|Cristiano Ronaldo and Conor McGregor step into the ring together|
|Mancini coy on reports linking Icardi to Napoli|
|Nolito reveals why he chose Man City over Barcelona|
|Inter 1 Paris Saint-Germain 3: Icardi absence in defeat fuels Napoli talk|
|MLS Review: Wright-Phillips double inspires Red Bulls to New York derby rout|
|James seeks more game time at Madrid|
|Rooney: I want to be a manager|
|Mignolet welcomes Karius challenge in Liverpool number one battle|
|Batshuayi buoyed by winning vibes at Chelsea|
|Moyes and Sunderland players diverted after plane fault|
|´Loved´ Varane targets long Madrid stay|
|Kostic set for Hamburg medical|
|Leicester crying over Kante sale - Ranieri|
|Schurrle the perfect Mkhitaryan replacement - Tuchel|
|West Ham face anxious wait on Cresswell injury|
|Mourinho will accept criticism from United legends|
|Bertolacci desperate for fresh start after underwhelming first season at Milan|
|Hoops hand Toure one-year deal|
|Origi ready to fight for Liverpool spot|
|Emery wants PSG stay for ´fantastic´ Matuidi|
|No Barcelona offer for Vietto - Cerezo|
|Burnley apologise for racist abuse from supporter|
|Guardiola will not rush Kompany comeback|
|Of course I´ll shake Guardiola´s hand, snaps riled Mourinho|
|Watzke: No more signings for Dortmund|
|Roma expect Manolas to snub Premier League move|
|Adriano set to leave Barcelona for Besiktas|
|Manchester United in worst possible situation - Mourinho|
|Sporting would have to sell stadium to afford Van Persie - Jesus|
|Jonas´ agent confirms Barcelona approach|
|No problem with Mourinho, insists Guardiola ahead of derby in China|
|Toronto´s hat-trick hero Giovinco: I´m back|
|Drogba revels in ´special night´, dedicates hat-trick to family|
|MLS Review: Hat-tricks for Drogba and Giovinco as stars shine|
|Whelan backs Liverpool for top-four finish|
|Pellegrini still waiting for right offer|
|Ronaldo deserves to win Ballon d´Or - Vazquez|
|Phelan wants Hull job|
|Alaba saddened by Gotze exit|
|Morgan: Vardy right to re-sign|
|Maradona ´hurting´ as Higuain closes on Juventus move|