Arsene Wenger endured a woeful 1,000th game in charge of Arsenal as Premier League leaders Chelsea romped to a 6-0 win at Stamford Bridge.
The Frenchman has never tasted victory over Chelsea boss Jose Mourinho and that record continued on Saturday as Arsenal were taken apart in embarrassing fashion.
Samuel Eto'o and Andre Schurrle capitalised on poor defending to put the hosts two goals ahead inside seven minutes.
Things soon got worse for Arsenal as Alex Oxlade-Chamberlain handled on the line after 15 minutes to concede a penalty that Eden Hazard converted, with Kieran Gibbs bizarrely sent off by referee Andre Marriner following an apparent case of mistaken identity.
Oscar then added further goals either side of half-time and substitute Mohamed Salah also got in on the act to round off a day that must rank among the worst of Wenger's lengthy tenure.
Arsenal now sit seven points behind Chelsea having played a game fewer, and their dismal performance continued a worrying trend this season in away matches against title rivals.
Wenger's side had already suffered 6-3 and 5-1 defeats at the hands of Manchester City and Liverpool respectively and now appear likely to complete another season without a Premier League title.
Schurrle and Eto'o were each recalled, together with David Luiz, to a Chelsea side missing Ramires and Willian through suspension.
An unchanged Arsenal threatened after four minutes when Olivier Giroud forced Petr Cech into a sharp low save following a neat throughball from Tomas Rosicky.
Yet Chelsea then moved ahead almost immediately as a swift counter-attack ended with Schurrle switching the ball right to Eto'o, who cut inside Oxlade-Chamberlain before curling a delightful shot past Wojciech Szczesny.
Arsenal soon found themselves horribly exposed once again. Nemanja Matic dispossessed Santi Cazorla before finding Schurrle and the German forward capitalised on defenders backing off by firing into the bottom-left corner.
Remarkably, the visitors' first-half display had yet to reach its nadir and Hazard added a third Chelsea goal from the penalty spot after his shot had been handled by Oxlade-Chamberlain.
Referee Marriner chose to dismiss Gibbs for the offence, despite Oxlade-Chamberlain appearing to confess his guilt.
The game was effectively over as a contest following the sending-off and Chelsea pulled further clear after 42 minutes when Fernando Torres, an early replacement for the injured Eto'o, crossed from the right for Oscar to convert.
Neither Oxlade-Chamberlain nor Laurent Koscielny emerged for the second half, which began with Szczesny denying Luiz after more good work from the lively Torres.
Cazorla dragged a shot narrowly wide on the hour mark, before another Arsenal error led to Chelsea scoring again in the 66th minute.
A sloppy pass from Rosicky found Oscar and the Brazilian beat Szczesny with a low strike that the goalkeeper may feel he should have saved.
Mourinho's men were not finished there and Salah, who had only just come on for Oscar, made it 6-0 five minutes later, beating the offside trap to break clear and score his first goal since arriving from Basel.
That ensured Chelsea scored six in a Premier League game for the first time under Mourinho, emphatically spoiling Wenger's landmark day.
|Coach: José Mourinho|
for S. Eto'o 10'
for Oscar 67'
for David Luiz 72'
|Schmidt ready for Kaiserslautern clash|
|West Ham v Chelsea: Mourinho turning attention back to the league|
|Barca must not be distracted by Clasico, says Busquets|
|Terry rules out England return|
|De Boer demands more despite PSV win|
|Bony: We have to win every game|
|Subotic rejects Serbia call-up|
|Benitez frustrated at refereeing decisions|
|Real Madrid must learn from Villarreal draw - Marcelo|
|QPR announce losses of £9.8m|
|Rutten to leave Feyenoord|
|First trophy for ´new´ Chelsea - Mourinho|
|Icardi the future of Inter, says Ausilio|
|Patience needed from ´brilliant´ United fans - Rooney|
|Allen hails ´next level´ Coutinho|
|Points over milestones for Cisse|
|Hecking ´furious´ with Wolfsburg defence|
|CONCACAF Champions League Preview: DC United face uphill task to reach semis|
|AFC Champions League Preview: Al Ain enhanced, Wanderers prepare for Evergrande reunion|
|Coupe de France Preview: PSG, Monaco to meet again|
|Crouch happy to silence doubters|
|Blanc questions rivals´ mental strength as PSG gain ground|
|Kane: Fortune favoured Chelsea|
|Ancelotti defends Isco substitution|
|Rooney: Di Maria will come good|
|Stubborn Villarreal impress Real´s Pepe|
|PSG could not ´kill off´ Monaco - Van der Wiel|
|Serie A Review: Napoli suffer defeat at Torino, Lazio lurking|
|Ligue 1 Review: Title chasers´ slip-ups go unpunished|
|La Liga Review: Real and Atletico suffer frustrating draws|
|Primeira Liga Review: Porto´s Tello dents Sporting´s title hopes|
|Monaco 0 PSG 0: Champions miss chance to go top|
|Real Madrid 1 Villarreal 1: Moreno leveller ensures stalemate|
|Simeone satisfied with Sevilla point|
|Henry: Chelsea can win a trophy treble this season|
|Mancini frustrated by ´hesitant´ Inter|
|Sevilla 0 Atletico Madrid 0: Simeone´s men in fiery draw|
|Pochettino upbeat despite League Cup defeat|
|Inter 0 Fiorentina 1: Montella´s men end San Siro wait|
|Bundesliga Review: Wolfsburg edge eight-goal thriller, Monchengladbach win|
|Mourinho revels in ´beautiful´ League Cup success|
|Eredivisie Review: PSV lose home record as Ajax close the gap|
|Terry thrilled by ´massive´ League Cup final win|
|Chelsea 2 Tottenham 0: Mourinho´s men seal League Cup success|
|Coquelin sustains broken nose|
|Wenger hails Giroud character after Everton goal|
|Everton not getting what they deserve - Martinez|
|Coutinho is coming of age at Anfield - Rodgers|
|Football League Preview: Wolves in the hunt for back-to-back promotions|
|Norwich City 2 Ipswich Town 0: Neil´s men go third with derby triumph|
|Southampton v Crystal Palace: Fonte focusing on big picture|
|Arsenal 2 Everton 0: Giroud strikes to silence doubters|
|Dynamo Dresden v Borussia Dortmund: Hummels eager to build on derby win|
|Rodgers tips hat to relentless Liverpool|
|City facing uphill challenge to retain title - Pellegrini|
|Celtic 4 Aberdeen 0: Champions dominate top-of-the-table clash|
|Lallana hails ´massive´ win as Liverpool´s top-four charge continues|
|Hull City v Sunderland: Cattermole allowing no excuses against ´bogey team´|
|Liverpool 2 Manchester City 1: Coutinho dents City´s title hopes|
|Sunderland to appeal Brown red card|
|Aston Villa v West Brom: Sherwood looking for confidence boost|
|Allegri not taking risks on Vidal and Pogba|
|Pardew defends Jedinak over Sakho elbow|
|Heldt apologises after Schalke´s derby humbling|
|Milan must give that bit extra - Bocchetti|
|Rooney: Brown red must be rescinded|
|Monk hails Swansea´s versatility|
|Melbourne Victory 2 Wellington Phoenix 3: Hosts miss chance to go top|
|Rodgers: Top-four finish would be bigger than last season´s effort|
|Batman and Robin ´a bit of fun´ - Reus|
|Rakitic feeling better after ending goal drought|
|Copa Libertadores Preview: Well-rested Cruzeiro ready for Universitario|
|Fournier fuming after Lyon loss|
|DFB Pokal Preview: Gladbach visit rusty Offenbach|
|Mourinho: Tottenham approached me|
|Primeira Liga Review: Birthday boys Benfica hit Estoril for six|
|Inzaghi finds positives in lacklustre display|
|Eredivisie Review: AZ move third, Propper fires Vitesse to victory|
|Chievo 0 Milan 0: Pressure back on Inzaghi|
|Bundesliga Review: Derby win for Dortmund superheroes, Leverkusen go fourth|
|Ligue 1 Review: Lyon loss leaves door open for PSG|
|Bueno nets perfect hat-trick in four-goal spree for Rayo|
|Carver impressed with Newcastle´s fighting spirit|
|Van Gaal explains Di Maria decision|
|Luis Enrique angered by Granada pitch|
|Sherwood confident of Villa survival|
|Referee East says ´no mistaken identity´ as Poyet pledges to look again|
|League One Review: Robertson and Johnson off to winning starts, Bristol City go eight clear|
|Bruce angered by missed decision|
|Berahino can be ´top class´ - Pulis|
|Grateful Gutierrez thanks ´special´ fans|
|Monk targets Swansea points record|
|Klopp´s ´perfect´ afternoon|
|Victory soured by Ireland injury, says Hughes|
|Championship Review: Middlesbrough´s opportunity missed as Derby are defeated|
|Koeman: I am realistic on Champions League|
|League Two Review: Burton beaten again, Hartlepool gain welcome lift|
|´Triple punishment´ rule could be scrapped|
|Scottish Premiership Review: Inverness slip up as strugglers prosper|
|Mancini wary of Fiorentina quality|
|Hearts attack hits double figures in Scotland|
|West Brom 1 Southampton 0: Berahino wins it, then limps off|
|Manchester United 2 Sunderland 0: Rooney at the double amid red card controversy|
|Newcastle United 1 Aston Villa 0: Cisse strike downs visitors|
|Stoke City 1 Hull City 0: Super sub Crouch secures win|
|Granada 1 Barcelona 3: Suarez inspires routine win|
|Burnley 0 Swansea City 1: Trippier own goal proves decisive|
|Borussia Dortmund 3 Schalke 0: Late show seals dominant derby win|
|Referee Dowd fails to make it through West Brom, Saints clash|
|Allardyce ´shocked´ after home loss|
|Pardew lauds Murray after ´mixed afternoon´ for striker|
|West Ham 1 Crystal Palace 3: Pardew enjoys more away-day success|
|Blanc: PSG prepared for confident Monaco|
|Ancelotti: Isco place is non-negotiable|
|Pellegrini out to end dismal record at Anfield|
|Roma v Juventus: Matri eyes glory in title tussle|
|Martinez wary of wounded Arsenal|
|A-League Review: Spectacular Sydney derby the highlight|
|Perez to testify in corruption case|
|Bentaleb determined to avoid European hangover|
|Liverpool cannot dwell on Europa exit, says Rodgers|
|Marquinhos welcomes Manchester United interest|
|Tottenham must be ´nearly perfect´ to beat Chelsea - Pochettino|
|Bielsa: I take responsibility|
|League Cup final ´most important´ for Mourinho|
|Rodgers unsure if European exit will be a blessing|
|Vitoria Guimaraes 1 Maritimo 0: Hosts end winless run|