Olympiacos can deliver another hammer blow to an ailing Manchester United when the duo meet in the UEFA Champions League.
The Premier League holders welcome the Greek club - who won their fourth straight league title on Saturday - to Old Trafford on Wednesday for the second leg of a last-16 tie, desperate to overturn a 2-0 deficit from the return match.
United manager David Moyes has come increasing pressure at Old Trafford following a disappointing maiden campaign, and his misery was compounded by a hugely disappointing 3-0 loss at home to rivals Liverpool on Sunday.
A brace of penalties from Steven Gerrard helped to inflict a fifth home league defeat of the campaign on United, but perhaps more worrying for Moyes was the way his side were outplayed by Brendan Rodgers' men.
The Champions League can now provide some solace for Moyes, whose side trails Chelsea by 18 points in the English top flight, with Europe's premier competition providing United's last chance of silverware this season.
To progress to the quarter-finals United will have to erase Olympiacos' two-goal cushion, gained through strikes from Alejandro Dominguez and on-loan Arsenal forward Joel Campbell.
Moyes has vowed United will turn the tie on its head, acknowledging the need to start Wednesday's game well.
"We have to go for the throat to get the win," he said. "We won't be gung-ho but we will certainly go with a mindset to overhaul the deficit as quickly as we can.
"We won't be reckless as we could find ourselves with a bigger mountain to climb, but we can be forceful. We have to be if we're to keep ourselves in the Champions League."
Olympiacos have lost on all of their previous 11 visits to England, but travel to Old Trafford on the back of lifting a 41st Greek title with five matches to spare, thanks to a 2-0 victory over Panthrakikos.
Furthermore, Michel's men showed they are more than capable of competing against United in the first leg at the Karaiskakis Stadium, and they will look to pounce on any mental fragility the hosts show following the Liverpool defeat.
United head into the match without Jonny Evans (calf), while Michael Olaitan has not played for Olympiacos since collapsing against Panathinaikos at the beginning of March.
Ivan Marcano (groin) and Javier Saviola (quadriceps) are doubts for the visitors, while Dominguez, Kostas Manolas and Diego Fuster are all one booking away from a suspension that would rule them out of a quarter-final tie.
|20||R. van Persie||25' 45+1' 52'|
|Coach: D. Moyes|
for A. Valencia 77'
for D. Welbeck 82'
for R. van Persie 90+1'
|Mourinho has ´got to grips´ with United - Ferguson|
|Uganda v Mali: A lot at stake for Mali in shot-shy showdown|
|Napoli 1 Fiorentina 0: Callejon heads Partenopei into semi-finals|
|Bordeaux 1 Paris Saint-Germain 4: Cavani, Di Maria secure final berth|
|Watzke: Dortmund would consider €80m for Aubameyang|
|Togo 1 DR Congo 3: Kabananga´s goal streak continues as Ibenge´s men top group|
|Morocco 1 Ivory Coast 0: Alioui stunner sends holders crashing out|
|Romeu earns Southampton extension as Puel targets away goal|
|Sunderland striker Anichebe out for up to 10 weeks|
|Elneny wants to be an Arsenal legend ´like Thierry Henry´|
|Corini leaves Palermo as Ballardini is tipped for fourth return|
|Hernandez leaves Leicester for Malaga|
|Lukas PodGOALski...Gala forward nets five amid J-League links|
|CAS rejects Serbian appeal against Kosovo UEFA membership|
|Thiago back in Bayern training as Arsenal showdown looms|
|Thiago back in Bayern training as Arsenal showdown looms|
|Shearer´s Toon Army ´trump´ the POTUS|
|Rooney´s record may stand forever - Ferguson|
|Carrick expects full-strength United as Wembley return beckons|
|They insulted his mother and then there were monkey noises - Cyprien on Bastia Balotelli abuse|
|No Chelsea regrets for Sampaoli as Sevilla mount title challenge|
|Egypt v Ghana: Cuper backs Elneny to deliver in crucial Group D clash|
|James adds to Zidane´s injury woes at Madrid|
|Zidane wants fans behind Madrid after latest Ronaldo whistles|
|Mason ´continues to make excellent progress´|
|Allegri slams ´stupidity´ surrounding Buffon referee hug|
|Niang in talks over AC Milan exit, confirms Montella|
|Sunderland sign Lescott|
|China-bound Ramos completes loan switch to Granada|
|Rahman to miss ´several months´|
|Leekens quits after Algeria´s AFCON exit|
|Jese has firm Premier League offer, claims Las Palmas president|
|´I´m blessed with golden genes´ - Adebayor insists he is ready for new Premier League chance|
|Messi renewal progressing ´very, very well´ - Robert|
|Neuer expects Clement success at Swansea|
|Klopp calls for Liverpool enjoyment|
|Mustafi talks up Arsenal belief|
|Van Basten still against offside, slams ´nonsense in the media´|
|Rakitic dreaming of career-long Barcelona stay|
|Toure inspired by Ibrahimovic as he explains Chinese Super League snub|
|Kasperczak committed to attacking approach as Tunisia reach AFCON quarters|
|Slimani wants Algeria youngsters to learn from AFCON humiliation|
|Senegal 2 Algeria 2: Slimani at the double as Desert Warriors bow out|
|Zimbabwe 2 Tunisia 4: First-half glut seals progression|
|Adrian: I always wanted to return to Villarreal|
|Togo v DR Congo: Agassa could miss crucial game after vandals hit home|
|Extended Southampton stay on the cards for Sims|
|Bayern hoping for speedy Vidal return|
|Hull sign Markovic on loan from Liverpool|
|Wenger charged with misconduct by FA|
|Deulofeu joins AC Milan - and this time the deal is definitely done!|
|Henderson still playing through pain, reveals Klopp|
|Record-breaking Rooney reveals secret to longevity|
|No ulterior motive behind Van Dijk captaincy call - Puel|
|Carroll ignoring want-away Payet|
|Gerrard´s managerial ambitions ´wonderful news for Liverpool´ - Klopp|
|PSG interested in Guedes, confirms Emery|
|Barca lose Busquets to sprained ankle|
|Pulisic commits to Dortmund until 2020|
|Mason speaking after suffering fractured skull|
|Aubameyang blames poor preparation for Gabon AFCON exit|
|David Beckham returns to PSG|
|Morocco v Ivory Coast: Holders must beat old boss Renard as group reaches thrilling conclusion|
|Djilobodji charged over Fletcher incident|
|Cahill and Terry visit Mason in hospital|
|Allardyce onto second-choice transfer targets|
|Dortmund sign teenager Isak|
|Madrid confirm Modric and Marcelo injury blows|
|Vidal fears longer lay-off, targets return against Arsenal|
|Yaya Toure: Sterling should have dived!|
|Turan wants to see out Barcelona contract despite China talk|
|Impassioned Ibrahimovic attacks Rooney´s critics|
|´He has to lose weight´ – Mihajlovic angry after dropping Maxi Lopez|
|Lack of Liverpool signings frustrates Klopp|
|Suarez: Busquets difficult to replace for Barca|
|Depay impresses Lyon after debut|
|CSL? Rooney committed to United|
|Denis Suarez wants more goals after opening Barca account|
|Simeone bemoans inconsistency but says Atletico are improving|
|Mourinho won´t stand in the way of Rooney and CSL|
|Dzeko on target as Roma stay on Juve´s tail|
|Rakitic ready to cover for injured Busquets|
|Bale and Kane wish Mason well after serious injury|
|Busquets injury less severe than feared - Luis Enrique|