Barcelona host Osasuna on Sunday with coach Gerardo Martino under pressure after disappointing results that have dented their title hopes.
The Catalan club's prospects of retaining the La Liga crown have been significantly damaged after a number of surprising defeats in recent weeks.
Martino's men were stunned 1-0 by struggling Real Valladolid last weekend, slumping to a loss against a side that is battling against relegation and had won just four previous league matches this campaign.
That setback made it three defeats in six league games for Barca, with the other two reverses coming against Valencia and Real Sociedad respectively.
Barca are third in La Liga as a result of their poor form, four points adrift of league leaders and arch rivals Real Madrid.
Valladolid's shock victory over the 22-time Spanish champions has led to scathing criticism of Martino, whose position has come under increasing scrutiny.
However, the Argentinian was able to silence his critics somewhat in midweek with a 2-1 (4-1 agg) success against Premier League side Manchester City in the UEFA Champions League last 16.
And Barca will be confident of building on that triumph against an Osasuna side that has lost on all of their last five visits to the Camp Nou in all competitions, conceding 21 goals.
Osasuna did hold Barca to a 0-0 draw in the reverse fixture in October, but two consecutive defeats have seen them pulled back into the battle against relegation.
Javi Garcia's side are only three points clear of safety heading into the weekend's fixtures, with 11 games remaining, and could be pulled even further towards the drop with defeat at Barcelona.
However, despite Osasuna's current struggles, striker Oriol Riera, who spent six years as a youngster at Barcelona, is hopeful they can prove to be a test for their hosts.
"Playing against one of the top three sides is always very difficult, but we're going there keen to make things difficult for them," he told the club's official website.
"We will make their lives difficult. At least, that's what we’ll be trying to do."
Jonathan dos Santos (knee) and Isaac Cuenca (hamstring) are both out for Barcelona, and Martino may elect not to play defender Gerard Pique, who is on the verge of a suspension.
Pique is one booking away from a ban and will miss next weekend's Clasico clash with Real should he receive a yellow card on Sunday.
Meanwhile, Osasuna could welcome back defender Marc Bertran (hamstring), while Sisi (knee) and Miguel de las Cuevas (toe) are still on the sidelines.
|10||L. Messi||18' 63' 88'|
|Coach: G. Martino|
for Xavi 61'
for A. Sánchez 77'
for J. Mascherano 82'
|Werder Bremen v Borussia Dortmund: Bundesliga stugglers targeting morale-boosting win|
|Medellin 1 Santa Fe 2: Visitors fight back to win|
|Barcelona 1 Emelec 1: Ecuadorian Primera A Third Stage play-off evenly poised|
|Sporting Cristal 0 Juan Aurich 0: Third leg required to decide Peruvian champions|
|Bauza ´delighted´ after San Lorenzo reach final|
|Paris Saint-Germain v Montpellier: PSG look to build|
|Bundesliga Preview: Bayern seeking to extend unbeaten start before winter break|
|Contra, Michel join Guangzhou R&F|
|Naismith signs Everton extension|
|Palestino 3 Santiago Wanderers 1: Title drought almost over for hosts|
|Copa del Rey Review: Finnbogason breaks drought in Sociedad win|
|Coupe de la Ligue Review: PSG scrape into quarters, Lille, Monaco win on penalties|
|Worcester City 1 Scunthorpe United 1 (aet, 13-14 on pens): League side narrowly avoid shock|
|Stambouli hails ´perfect´ Tottenham|
|Goals win games - Pardew|
|Bundesliga Review: Dortmund held by late equaliser, Leverkusen beat Bremen|
|PSV 4 Feyenoord 3: De Jong hat-trick helps settle thriller|
|Rodgers hails ´brilliant´ Liverpool|
|Eredivisie Preview: Leaders PSV take on struggling Eagles|
|Madoui hails second-half display|
|Championship Preview: Reading´s Clarke era begins at Watford|
|Liverpool to meet Chelsea in League Cup semi-finals|
|San Lorenzo 2 Auckland City 1: Extra time required to book Real final|
|AC Ajaccio 1 PSG 3: Late show sends holders through|
|Bournemouth 1 Liverpool 3: Sterling brace helps ease pressure|
|Tottenham 4 Newcastle United 0: Pochettino´s men march into semi-finals|
|Borussia Dortmund 2 Wolfsburg 2: Naldo denies Klopp´s strugglers|
|League Two Preview: Moore looks for fighting spirit, Accrington aim to bounce back|
|Allegri has suspension overturned|
|ES Setif 2 Western Sydney Wanderers 2 (5-4 on pens): Algerians rely on penalties to finish fifth|
|Ligue 1 Preview: Fournier not expecting to claim top spot, Marseille entertain Lille|
|Indian Super League Review: Kerala through to face Kolkata in final|
|Lasogga suffers thigh strain|
|Michael Garcia FIFA resignation notice in full|
|Bayern draw not ideal - Lucescu|
|Garcia resigns from FIFA role|
|Mainz v Bayern Munich: Bavarians on brink of more records|
|Garcia to fight two-match ban|
|Green backs Mignolet to return stronger|
|Mandzukic and Koke to lead inexperienced Atleti XI|
|Fonte apologises to fans after cup defeat|
|Metz suspend Maiga after unauthorised absence|
|Agent: Cole settled at Roma|
|Bayern duo sign new deals|
|Allegri calls for Juve focus ahead of Cagliari trip|
|Pearson accepts FA charge after fan row|
|Mourinho rules out January signings|
|Schaars set for PSV absence after knee surgery|
|Traore wants more Barca chances|
|Hamann hopes Liverpool receive cup boost|
|Lukaku wants Everton to produce Premier League best in Europe|
|La Liga Preview: Barca host Cordoba, Atletico travel to Bilbao|
|A-League Preview: Berisha crucial for Milligan-less Victory|
|Tena: Real ´by far the better team´|
|Blanc avoids Mourinho mind games, hails retiring Henry|
|Hecking convinced Dortmund remain dangerous|
|United´s Jones insists injuries are behind him|
|Henry: Managing Arsenal is my dream|
|Hard to imagine a better performance - Luis Enrique|
|Copa del Rey Review: Goals rain in Spain|
|Benatia to sit out Mainz clash|
|Koeman slams ´disrespectful´ Sheffield United|
|Barcelona 8 Huesca 1 (12-1 agg): Pedro treble sets up big win|
|Coupe de la Ligue Review: Nantes come from two down, Bastia knock out Caen|
|Penalty save was key, says Ancelotti|
|Mourinho pleased with professional approach in Derby win|
|FA Cup Review: Yeovil set up Man United clash, Tranmere to face Swansea|
|Bundesliga Review: Stuttgart move off bottom, Bayern win again|
|Sheffield United 1 Southampton 0: McNulty secures semi-final spot for third-tier side|
|Derby County 1 Chelsea 3: Premier League leaders progress|
|Cruz Azul 0 Real Madrid 4: Spanish giants cruise into final|
|Bayern Munich 2 Freiburg 0: 100 not out for Robben as champions cruise|
|Cagliari v Juventus: Barzagli unconcerned by successive draws|
|ECA and EPFL make case for May World Cup in 2022|
|Atletico Madrid v L´Hospitalet: Simeone likely to rotate|
|Serie A Preview: Morata chasing goals, Roma host Milan|
|Hartlepool appoint Moore following takeover|
|Parma appoint new president|
|Garcia handed two-match ban|
|Reading appoint Clarke to replace Adkins|
|Conte rules out resignation|
|Adebayor will not face Newcastle - Pochettino|
|Zhang seals Wolfsburg switch|
|SFA rejects Tonev appeal|
|Garcia report appeal rejected by FIFA|
|Herrera denies involvement in match-fixing|
|Thierry Henry: Moments that defined a genius|
|UEFA opens proceedings against Celtic|
|Rodgers denies talk of dressing-room rift|
|Jonas will be given a chance - Pardew|
|AFC asks Australia to increase security for Asian Cup|
|D´Ambrosio sets Inter sights on third|
|Williams wants Swansea to share goalscoring burden|
|Saudi Arabia appoint Olaroiu|
|Martinez lauds Barkley|
|Thierry Henry announces retirement|
|Rooney: United can win title|
|ES Setif v Western Sydney Wanderers: Topor-Stanley to miss fifth-place play-off|
|Beasley calls time on international career|
|Tena: We expect to face Real´s best|
|Martinez wary of Young Boys´ artificial pitch|
|Dudek: Everyone under pressure at Liverpool|
|Martinez hails ´devastating´ attack|
|Redknapp: QPR´s road woes more than bad luck|
|Defeat harsh on QPR - Redknapp|