Robert Lewandowski has been ruled out of Poland's friendly with Scotland due to a knee injury, Borussia Dortmund have confirmed.
The striker, who will join Bundesliga leaders Bayern Munich at the end of the season, has been in fine form for Dortmund so far in 2013-14, as he has scored 22 goals in 34 appearances.
Lewandowski had been due to captain Poland on Wednesday in Warsaw in the absence of Dortmund team-mate and regular skipper Jakub Blaszczykowski.
However, the former Lech Poznan forward will miss the chance to lead out Adam Nawalka's side as Poland look to build towards the UEFA Euro 2016 qualifiers.
And the 25-year-old could also miss out on Dortmund's Bundesliga meeting with Freiburg on Sunday.
"I have a slight tear of the cruciate ligament. The doctor says I shouldn't play on Sunday," Lewandowski told Bild.
Lewandowski's prospective absence will come as a blow to a Dortmund side already missing Blaszczykowski, Neven Subotic, Sven Bender and Ilkay Gundogan through long-term injuries.
A statement on Dortmund's official website read: "Borussia Dortmund striker Robert Lewandowski will not be in action for the Polish national team on Wednesday. He is unavailable for the match against Scotland because of knee problems.
"After his return from Warsaw to Dortmund Lewandowski will be examined by team doctor Markus Braun, to diagnose the precise extent of the injury."
|Coach: A. Nawałka|
for S. Peszko 74'
for L. Obraniak 74'
for M. Klich 82'
for G. Krychowiak 88'
for W. Sobota 89'
for T. Brzyski 90+2'
|Warnock sacked by Palace|
|Aston Villa v Sunderland: No club too big to go down, says Lambert|
|Hull City v Leicester City: Pearson vows to keep going|
|Stoke City v West Brom: Hughes targets elusive back-to-back wins|
|Rodgers dismisses Balotelli exit rumours|
|Modric will not rush Madrid return|
|Dyche pleased with Vokes return|
|Southampton v Chelsea: Koeman vows to go on the offensive|
|A-League Review: Six-goal Gosford thriller, Victory leave it late|
|Manchester City v Burnley: Pellegrini warns against complacency|
|Dortmund can fight on two fronts - Watzke|
|Sterling hails improved Liverpool belief|
|Rosicky eager to build on QPR winner|
|Wenger: ´We made it hard for ourselves´|
|Kane: Spurs eye top four|
|Di Maria in doubt for Spurs clash|
|Ba left out of Senegal AFCON squad|
|Redknapp frustrated by penalty call|
|Wenger sees Giroud wrongs|
|Premier League schedule a ´disgrace´, says Poyet|
|Championship Review: Bournemouth stay top, Heskey scores on Bolton debut|
|Hughes lauds Bojan performance|
|Koeman: Saints marching on|
|Pardew rues referee error|
|Arsenal 2 QPR 1: Sublime Alexis secures the spoils|
|Martinez questions Walters decision|
|Poyet laments Sunderland mistakes|
|League One Review: Swindon cruise to win over Walsall|
|Irvine aware of need for improvement|
|United still doing ´very bad things´ - Van Gaal|
|Lambert proud of players despite Swansea defeat|
|Warnock bemoans Palace defence|
|Bruce hails Hull´s spirit|
|Pochettino relieved to come away with victory|
|Dyche: We had our pocket pinched|
|Monk hails Fabianski performance|
|Pearson demands greater concentration from Leicester|
|Kompany set for City return|
|Rodgers hails character after battling win|
|League Two Review: Ainsworth frustrated by Luton, Shrewsbury go top|
|Everton 0 Stoke City 1: Lacklustre Everton slip to defeat|
|Sunderland 1 Hull City 3: Triumphant return for Bruce|
|Burnley 0 Liverpool 1: Sterling wins it at Turf Moor|
|Leicester City 1 Tottenham 2: Eriksen piles misery on Pearson´s men|
|Manchester United 3 Newcastle United 1: Rooney extends hosts´ streak|
|West Brom 1 Manchester City 3: Three and easy for in-form champions|
|Swansea City 1 Aston Villa 0: Hosts break Boxing Day duck|
|Crystal Palace 1 Southampton 3: Mane marks return with star performance|
|Allardyce upbeat despite defeat|
|Van Dijk happy at Celtic - Deila|
|Table-topping Chelsea delight Mourinho|
|Chelsea 2 West Ham 0: Mourinho´s men ease to victory|
|Suarez enjoying Messi, Neymar link-up|
|A-League Review: Garcia rescues point for Perth, Adelaide up to second|
|Poyet calls for mid-season break|
|Van Gaal rules out Januzaj move|
|Rodgers: Balotelli may have to get used to bench|
|Lallana: I was trying too hard|
|Walker juggles music, football careers in Sweden|
|Song to face ´brother from another mother´ Fabregas|
|Adriano announces Le Havre deal|
|Pardew braced for Old Trafford test|
|Lescott unfazed by City reunion|
|Tskhadadze appointed Georgia coach|
|United to finish top three - Ferdinand|
|Allardyce: Stamford Bridge stalemate saved my job|
|Southampton need three January signings, says Watson|
|Liverpool can make Champions League, says fanzine editor|
|Walsh: Hull clash crucial for Leicester|
|Toure, Aubameyang and Enyeama make shortlist for African gong|
|Docherty backs Chelsea to win two-horse race|
|Liverpool could benefit from Hyypia influence - Scales|
|Saudi Arabia name Asian Cup squad|
|Forty-year-old Cahill no problem for Postecoglou|