Group C's early pacesetters meet in Brasilia on Thursday as Colombia and Ivory Coast seek to bolster their hopes of progression.
The nations won their respective opening matches on Saturday and another victory for either would all but secure their place in the knockout stages.
In a group where all four sides will have had high expectations of qualification when the tournament began, Colombia and Ivory Coast struck first as they triumphed over Greece and Japan respectively.
Jose Pekerman's team were in particularly impressive form as they swept aside the Greeks 3-0 while Sabri Lamouchi's men came from behind to beat Japan 2-1.
Ivory Coast started slowly in their opening clash and a repeat could cost them against a Colombia side who were ahead inside six minutes in their first game.
The return of Fredy Guarin following suspension will further bolster Colombia's attacking options and Jackson Martinez, who came off the bench against Greece, expects a tougher test than in their opener.
"Ivory Coast is a team who have grown a lot, they have a lot of experience," Martinez said.
"The match against Japan was a showcase of them being a team. You have to keep controlling the game until the end."
Dider Drogba was at his influential best against Japan - helping to inspire his side's recovery from a goal down after being introduced from the bench.
Lamouchi has hinted Drogba will likely begin Thursday's game on the bench again and the 36-year-old striker is content with a bit part role.
Regardless of whether he is handed a starting berth or not, Martinez still anticipates that the Galatasaray man will be a prominent figure for his country.
"We all know his quality, he's a big forward and he's done a lot of things in his career," the Porto striker added.
"He's a leader on the pitch and can lead his team to victory when things get complicated.
"He's a key player for the Ivory Coast either starting or coming off the bench."
It will be the first meeting between the two nations and the victor can take a huge stride towards wrapping up a last-16 berth, with Japan and Greece hoping to make up ground on the losers, or on both sides if the spoils are shared.
Between them, Colombia and Ivory Coast have reached the knockout stages at the World Cup just once previously but that looks set to change ahead of what promises to be an exciting, attacking affair.
Even without the injured Radamel Falcao and Carlos Bacca, the likes of Martinez, Adrian Ramos and Teofilo Gutierrez can threaten goals for Colombia while Wilfried Bony and Gervinho will hope to add their World Cup goal tallies for the Africans.
|Coach: J. Pekerman|
for V. Ibarbo 53'
for P. Armero 72'
for A. Aguilar 79'
|Atletico Mineiro 4 Lanus 3 (agg 5-3): Own goals gift Brazilians the win|
|Dunga names Brazil assistants|
|Man City show class in Kansas|
|Villa too good for Dallas|
|Santos cannot meet Robinho´s demands, says vice-president|
|Mourinho happy with goalkeeper situation|
|Palace held to draw by Crew|
|Borini hurt as Liverpool lose to Roma|
|Tottenham down Toronto after Lamela brace|
|San Lorenzo 5 Bolivar 0: Hosts close in on Copa Libertadores final|
|Sunderland forward Scocco joins Newell´s|
|Rodgers: We won´t overpay in transfer market|
|Maccabi Haifa friendly abandoned after pitch invasion|
|USA dynamo Beasley joins Houston|
|UEFA Champions League Review: Steaua ease through as Legia Warsaw hit five|
|Youngsters inspire Sunderland to win at Hartlepool|
|Aluko and Sagbo net as Hull City beat York|
|PSG loan Aurier from Toulouse|
|Emotional Davies thanks Swansea fans|
|Mandzukic makes debut as Atletico win|
|Filipe makes bow in Chelsea draw|
|Bahebeck stars again as PSG beat Nice|
|Conte rubbishes PSG talk|
|Tottenham sign Davies and Vorm as Sigurdsson joins Swansea|
|De Laurentiis vows Napoli will fight for Scudetto|
|Lyon sign Jallet from PSG|
|Rijeka deny racism allegations|
|Suarez has been treated ´like a murderer´, says Aspas|
|Basel secure Samuel swoop|
|Thai Premier League Review: Buriram go top as Muang Thong slip up|
|Dnipro-Copenhagen clash moved to Kiev|
|Tevez never considered Juve exit|
|Djuricic joins Mainz on loan|
|Cavani keen on PSG stay|
|Shaqiri flattered by Juventus link|
|Johnson, Sommer arrive at Monchengladbach|
|J.League Review: Kawasaki close gap on Sagan, Urawa move clear at top|
|Coleman to miss Everton´s Thailand trip|
|Thankful Rueda bids farewell to Ecuador|
|Liga MX Preview: Peralta set for home debut, Leon seek recovery|
|K.League Review: Top two draw blanks, Jeju United close in|
|CAF Champions League Preview: Zamalek primed for crucial game, CS Sfaxien meet ES Tunis|
|Low quashes Germany exit rumours|
|Getafe agree Michel loan|
|Porto bring in Brahimi from Granada|
|Pardew satisfied with attacking signings|
|Pellegrini targets further City signings|
|Sevilla complete Krychowiak deal|
|Eisfeld makes Fulham move|
|Zarate opens account as West Ham stumble|
|I have nothing to prove, says Ince|
|Barcelona seal Mathieu deal|
|United prepared to spend big, claims Woodward|
|Shakhtar to play in Lviv|
|Pereyra poised for Juve switch|
|Fabregas eyes trophies at Chelsea|
|Vorm confirms Tottenham transfer|
|Deila: Forster will leave Celtic eventually|
|No pressure for Shaw|
|Van Gaal happy with preparations|
|Diarra aiming for Bordeaux return after West Ham frustration|
|Last season for Montpellier owner Nicollin|
|Monaco: Rodriguez deal too good to ignore|
|Nacional Asuncion 2 Defensor Sporting 0: Hosts surge towards Libertadores final|
|Garcia eyeing Serie A title|
|Father against Vlasic´s move abroad|
|Rodgers welcomes Gerrard´s international retirement|
|Cruzeiro, Atletico Mineiro bid for Robinho|
|Inzaghi not drawn into Balotelli speculation|
|Dunga ´not going to sell a dream´|
|City´s Fofana allegedly racially abused|
|Carroll ruled out of NZ friendlies|
|Rodgers excited by new arrivals|
|Zeljeznicar 2 Metalurg Skopje 2 (agg 2-2): Visitors advance on away goals|
|Gibson returns as Tranmere hold Everton|
|UEFA Champions League Review: Celtic coast through, BATE given scare|
|Gomez and Jones feature in Sunderland win|
|Leicester hit Ilkeston for six|
|Austin fires QPR to narrow victory|
|Guardiola: No trophies and I may be sacked|
|Dortmund held as Immobile makes debut|
|Rodriguez´s dream becomes Real|
|Garcia: Benatia and Ljajic going nowhere|
|Stoke secure Bojan on four-year deal|
|FA: No World Cup bids for England|
|Kroos commits to Bremen|
|Caulker makes QPR move|
|Forest agree Hunt loan deal with Palace|
|Bartra ready to prove himself at Barca|
|Southampton looking to sell Osvaldo|
|Marveaux loaned to Guingamp|
|Mourinho eyes success on two fronts|
|Sammer encouraged by Lewandowski start|
|PSG punished for abuse of Chelsea fans|
|Dunga unveiled as Brazil coach|
|Shakhtar CEO: Focus is on players´ safety|
|Foster agrees new West Brom deal|
|Real Madrid sign Rodriguez|
|Mustafi eyes Bundesliga switch|
|Klopp laughs off Hummels, Reus speculation|
|Campana makes Sampdoria switch|
|Leicester seal Ulloa deal|
|Morata sidelined for seven weeks with knee injury|
|Riviere on target in comfortable Newcastle win|
|Advocaat set for Serbia role|
|Wisdom joins West Brom on loan|
|Bundesliga to consider vanishing foam|
|Five-man shortlist for Ivory Coast|
|´Personal issues´ keep Gervinho away from Roma tour|
|Jedinak raring to go|
|Borini set for Liverpool stay, claims agent|
|Koeman: No bids for Lovren|
|Livermore: England hopes shouldn´t hinge on club side|
|MLS Preview: Tough tests for Conference leaders, Revolution still struggling|
|Mathieu not Barca material, says Marquez|
|West Brom claim unimpressive win in Sacramento|
|Neymar: Brazil behind Germany, Spain|
|Vietnamese police confirm match-fixing players|
|Lucescu blames Joorabchian for AWOL players|
|Robinho undecided on future|
|Rush: Still years left in Gerrard|
|Tiago re-signs with Atletico|
|Puyol against Spain overhaul|
|Agger considering his Liverpool future|
|Peruvian Primera Division Review: Juan Aurich bounce back, Melgar draw with Inti Gas|
|Bayern deny interest in Cuadrado|