Spain's FIFA World Cup defence begins on Friday against their final opponents from four years ago, the Netherlands.
Vicente del Bosque's side triumphed in a bruising encounter aganst the Dutch in Johannesburg to confirm their dominance over the world game, though both sides are now in starkly different eras.
While just seven of Netherlands' 2010 vintage have retained their place ahead of their tournament opener at Salvador's Arena Fonte Nova, many of Spain's top stars have returned for a last tilt at glory.
The likes of Xavi, Iker Casillas and David Villa - so crucial to their consecutive European Championship wins and World Cup success - are likely playing in the competition for the final time.
One of the younger talents in the squad, Atletico Madrid midfielder Koke, will compete in his first international tournament as he looks to continue his stunning 2014.
After playing a pivotal role in Atleti's midfield as they secured a first Liga title since 1996, Koke feels privileged to have earned a place among what he believes is still a formidable winning unit.
"Spain always have a winning mentality," he told reporters. "We have kept the same philosophy, which is to go out and play with the same style that has characterised us for so many years - that's how this group became winners."
Spain's main fitness doubt surrounds Brazil-born striker Diego Costa, but Koke insists his Atleti colleague is close to being back up to full-speed after the latter part of his season was plagued by hamstring problems.
Costa managed to play 73 minutes in Spain's 2-0 friendly victory over El Salvador last week and Koke is excited to see the 25-year-old make his impact.
The midfielder added: "Of course he's ready. I think everyone could see that against El Salvador, he fulfilled everyone's expectations.
"He was looking sharp, he could sprint, and in training he has been the same. I think he is 100 per cent fit. If he wasn’t, he would have told the coach."
Netherlands also hope to have one of Europe's leading forwards ready to go after Robin van Persie was withdrawn as a precaution during their 2-0 friendly win over Wales with an apparent groin complaint.
With the exception of the Manchester United star, the Dutch squad will finish working with Louis van Gaal at the end of the tournament as the decorated coach leaves his post to embark upon a sizeable rebuilding job at Old Trafford.
Van Gaal's decision to experiment with a back-three setup during pre-World Cup friendlies raised eyebrows but Bayern Munich winger Arjen Robben is confident a remodelled system - starting against one of the most established styles in modern football - can bear fruit in Brazil.
He told FIFA.com : "We have played three matches with the new formation and none of our opponents - Ecuador, Wales and Ghana - created a lot of chances, whereas we did. I'm really confident that this is the best way for us to play in at the moment."
"I worked with him (Van Gaal) at Bayern Munich before he took this job, so he has been very important to my career. Along with (Pep) Guardiola, I can say he is the best coach I ever had."
|Coach: Del Bosque|
for Diego Costa 63'
for Xabi Alonso 63'
for David Silva 78'
|Ligue 1 Review: Marseille come from behind, Nantes extend unbeaten run|
|La Liga Review: Valencia suffer derby defeat, Rayo Vallecano beat Celta Vigo|
|Serie A Review: Mancini´s Inter rescue derby draw|
|Milan 1 Inter 1: Draw for Mancini on return|
|Pochettino wants home comforts|
|Bundesliga Review: Hamburg secure derby win, Stuttgart beaten again|
|Bruce disappointed with Vertonghen reaction|
|Eriksen backing Tottenham to kick on|
|Hull City 1 Tottenham 2: Eriksen snatches late winner after Ramirez sees red|
|Eredivisie Review: De Leeuw denies leaders PSV, Heracles secure timely win|
|Rodgers takes responsibility for Liverpool slump|
|Falcao ready for United return|
|Warnock basks in Palace display|
|Fabregas calls for ruthlessness|
|Crystal Palace 3 Liverpool 1: Rodgers´ men stumble at Palace again|
|Partick Thistle 0 Aberdeen 1: Rooney spot on for visitors|
|Reus blow for Dortmund|
|Mulvey leaves Roar post|
|Shakhtar Donetsk v Athletic Bilbao: Bernard eyes fast start|
|Forster urges Southampton to build|
|Sporting v Maribor: Montero out to continue hot streak|
|Schalke v Chelsea: Chance of revenge for Di Matteo|
|Manchester City v Bayern Munich: Pellegrini putting pressure on himself|
|Mourinho guards against Chelsea complacency|
|Rodriguez urges Real focus|
|Paris Saint-Germain v Ajax: Dutch outfit quietly confident|
|APOEL v Barcelona: Xavi seeks further improvement|
|Gotze basks in Bayern form|
|Tevez wants domestic form replicated in Europe|
|Mixed news on Naismith for Everton|
|Central Coast Mariners 0 Adelaide United 2: Sanchez nets brace for visitors|
|Can full of praise for Gerrard|
|BATE v Porto: Visitors eye top spot|
|CSKA Moscow v Roma: Italians eye qualification|
|Simeone lauds Atletico display|
|Messi the best ever - Luis Enrique|
|Eredivisie Review: Feyenoord make Peersman pay, Ajax beat Heerenveen|
|La Liga Review: Real Madrid, Barcelona win big|
|Allegri lauds Pogba performance|
|Messi pays homage after record-breaking day|
|Messi the record breaker|
|Serie A Review: Top two both victorious|
|Taylor hints that knee injury not as bad as first feared|
|Ligue 1 Review: Lyon stumble against Bastia|
|Van Gaal critical of United despite win|
|Lazio 0 Juventus 3: Pogba and Tevez star as champions dominate|
|Wenger frustrated by wasteful Arsenal defeat|
|Barcelona 5 Sevilla 1: Messi breaks La Liga record as Barca cruise|
|Garcia delighted with Ljajic display|
|League One Review: Swindon close the gap at the top, Yeovil off the bottom|
|Messi breaks La Liga goal record|
|Ancelotti: Isco a ´perfect´ Modric replacement|
|Bundesliga Review: Wolfsburg slip helps move Bayern well clear|
|Rooney revels in success of counter-attack ploy|
|Tiago: Malaga scalp proves we´re great|
|Arsenal 1 Manchester United 2: Rooney seals Van Gaal´s maiden away win|
|Reus injury angers Klopp|
|Schweinsteiger pays tribute to Bayern fans|
|Pellegrini salutes Toure´s attitude|
|Hughes laments Stoke´s slow start|
|Allardyce frustrated after Everton defeat|
|We deserved more - Redknapp|
|Irvine: Yacob can have no complaints|
|League Two Review: Luton run ended by Burton, Wycombe go top|
|Eibar 0 Real Madrid 4: Relentless Real win again|
|Poyet defends Cattermole over Cambiasso tackle|
|Dyche hails Burnley resolve|
|Martinez hails ´satisfying´ Everton triumph|
|Pearson sure of Leicester survival|
|Gomis earns Monk forgiveness for late miss|
|Pardew full of praise for Sissoko|
|Mourinho lauds ´beautiful´ Chelsea display|
|Scottish Premiership Review: Guidetti strikes again for Celtic, top four all win|
|Championship Review: Bamford denies Mackay´s Wigan, Derby extend lead|
|Aston Villa v Southampton: Koeman eyes international swagger|
|Newcastle United 1 QPR 0: Skipper Sissoko seals fifth straight win|
|Leicester City 0 Sunderland 0: Hosts´ goal drought continues|
|Stoke City 1 Burnley 2: Ings at the double as visitors hold on|
|Atletico Madrid 3 Malaga 1: Unconvincing champions halt in-form visitors|
|Everton 2 West Ham 1: Osman celebrates landmark with winner|
|Manchester City 2 Swansea 1: Toure seals comeback win for champions|
|Chelsea 2 West Brom 0: Yacob sees red as leaders march on|
|Paderborn 2 Borussia Dortmund 2: Reus injury leads to Dortmund capitulation|
|Bayern Munich 4 Hoffenheim 0: Champions move seven clear|
|Bielsa not concerned by Marseille investigation|
|Mancini buoyed by Inter preparations|
|Benitez rules out Liverpool return|
|Hertha prepared for Kalou absence|
|Montella confident despite Fiorentina pressures|
|Injured Alex out of Milan derby|
|Pochettino wants versatility from Dier|
|Van Gaal will not take risks with Falcao fitness|
|A-League Review: Sydney keep pressure on at top|
|K. League Review: Sangju Sangmu all but down, Gyeongnam remain in danger|
|J.League Review: Gamba deny title-chasing Urawa, Ventforet ensure safety|
|Rabiot thrilled with PSG return|
|Sterling wants long Liverpool stay|
|Poyet: I thought Cattermole would ´shoot´ me|
|Simeone: Cerci interest compliments Atletico|
|Blanc: ´I was confident´ of PSG win|
|Silva sidelined for crucial City-Bayern clash|
|Lambert would ´love´ to keep Vlaar, slams agent|