Didier Deschamps must weigh up his options ahead of France's showdown with Jamaica, after Franck Ribery was ruled out of the World Cup.
Les Blues' preparations for the marquee tournament were rocked by the news that the Bayern Munich winger will play no part in Brazil due to a back injury.
The 31-year-old had shown signs of improvements and it was hoped he could feature in Sunday's encounter with Winfried Schafer's men at Stade Pierre-Mauroy.
However, he suffered a setback during sprint tests on Friday and an MRI scan ruled him out of contention.
In a further blow, Olympique Lyonnais midfielder Clement Grenier has also been forced to miss the tournament in Brazil with a groin injury sustained in training on Thursday.
Montepellier's Remy Cabella and Southampton's Morgan Schneiderlin have been called up in their place, and the duo will hope for a chance to stake their claim against Jamaica.
For France coach Deschamps, the double blow is untimely as he bids to eradicate the memories of France's last two major tournaments.
France suffered the humiliation of finishing bottom of Group A with just a solitary point at the 2010 World Cup in South Africa, while the 2012 Euros ended in quarter-final heartbreak to eventual winners Spain.
Both tournaments were marred by reports of discontent in the French camp, but New York Bulls striker Thierry Henry believes Deschamps will maintain squad harmony.
The ex-Arsenal captain was part of the France squad captained by Deschamps that won the 1998 World Cup on home soil and the iconic forward has nothing but praise for his former team-mate's temperament.
"He can keep everyone happy," the former Arsenal man told the London Evening Standard.
"I don't know what it is with Didier: he was the first captain to lift the World Cup for France, he was the first captain for Marseille to win the Champions League for a French team.
"I don't know what it is with him but it is not luck anymore. He is working well and hard; he has all the tools to make the team happy and perform."
A run of just one defeat in their past 10 matches certainly suggests France are improving, and the current team have one last chance to stake a spot in the starting XI against a Jamaica side who are 64 places below them in the Fifa world rankings.
But Schafer's men have proved stern opposition in recently friendly encounters, and put in spirited displays in the 2-1 and 1-0 losses to Serbia and Switzerland respectively, before drawing 2-2 with Egypt in their latest outing.
With Caribbean Cup and Copa America campaigns on the horizon, Jamaica - who have only once qualified for the World Cup in 1998 - will no doubt relish the opportunity to test themselves against seemingly superior competition.
1 - 0
2 - 0
3 - 0
4 - 0
5 - 0
6 - 0
7 - 0
8 - 0
|14||B. Matuidi||20' 66'|
|6||Y. Cabaye||17' 44'|
|10||K. Benzema||38' 63'|
|Coach: D. Deschamps|
for M. Debuchy 46'
for Y. Cabaye 59'
for O. Giroud 71'
for B. Matuidi 72'
for M. Valbuena 80'
for K. Benzema 86'
|Argentina v Chile: New year, same Copa finalists|
|Ronaldo ´cannot be the whole of Portugal´ - Shilton|
|Messi: Neymar is an amazing person|
|Pekerman keen to finish Copa on high note|
|Rakitic: Ronaldo won´t sleep easily|
|Messi: Now is not a time to give nothing|
|Courtois expects to leave Chelsea in future|
|Less rest no problem for Portugal - Joao Mario|
|Euro 2016 Diary: Benteke rap and Nelly the elephant|
|Santos: Group-stage performances behind Portugal|
|Cacic: We cannot let Ronaldo show his strength|
|O´Neill hopes to blow Bale off course|
|Coleman impressed with Ramsey´s discipline|
|O´Neill fires derby passions ahead of Wales showdown|
|Coleman: Take emotion out of Northern Ireland clash|
|LFP sanctions six Nice players for flouting gambling rules|
|Hungary v Belgium: Lukaku targets last-four spot|
|Dyke hopes Brexit can help England youngsters|
|No favourites against Italy, says Koke|
|Krychowiak not thinking about PSG as Poland stand by Lewandowski|
|World Cup qualifying: Algeria, Cameroon and Nigeria drawn in same group|
|Brexit may damage Premier League´s pursuit of young European players|
|Germany v Slovakia: Weiss confident of repeat Augsburg success|
|France v Republic of Ireland: Long not on Henry revenge mission|
|Chelsea midfielder Baker extends Vitesse loan|
|Chiellini concerned over Brexit ´domino effect´|
|Staying in Euro 2016 gets Coleman´s vote|
|Nainggolan has a room with a balcony so he can smoke - Wilmots|
|Petkovic attempts Poland mind games|
|Wilmots would rather play Spain than Hungary|
|Morata deserves more than being a Madrid bargaining chip - Chiellini|
|AZ want record fee for Janssen|
|What does Brexit mean for European football?|
|I´m not tired, I feel sharp - Kane hits back at critics|
|Delighted Kiyotake hopes to prove his value|
|Premier League confident Brexit will not diminish its success|
|Neuer wary of Hamsik´s long-range shots|
|Genesio: Lyon do not have to sell|
|Morata thanks Juventus fans after Real Madrid return|
|Lapadula undergoes AC Milan medical|
|Santos: Not everything revolves around Ronaldo|
|Icelandic chihuahua prepares to chase the England rhino|
|Jakupovic signs new Hull City contract|
|Lagerback: Brexit will not affect England team|
|ES Setif disqualified from CAF Champions League|
|Gerland sees Kimmich as Lahm´s long-term successor|
|Navas ´recovering nicely´ from heel injury|
|Messi excited by future Barcelona challenges|
|Conte´s Italy like Atletico and Barcelona, says Xavi|
|Zidane the man to take Madrid forward, says Baptista|
|United States v Colombia: Hosts out to end Copa America on a high|
|Aubameyang: It´s my dream to play in Spain|
|Wenger not interested in France job|
|Ronaldo: Euro 2016 surprises end now for Portugal|
|Coke hopeful Sampaoli can exceed Emery at Sevilla|
|Maradona: Portugal too dependent on Ronaldo|
|´What a disaster´ - Messi takes aim at AFA|
|Guidetti: Nolito will thrive at City|
|Wanyama thanks Southampton fans following Spurs switch|
|Kranjcar: Rangers can push Celtic all the way|
|Euro 2016 Diary: Icelandic heaven and Rooney not feeling the love|
|Wenger respects Vardy, talks up Kante|
|Rooney wants to end ´disappointing´ tournament record for England|
|Di Maria in serious doubt for Copa America final|
|´We gave it all´, Alaba tells Austria fans|
|Euro 2016 Social Round-Up: Last 16 sides prepare for the knockout rounds|
|Osorio to stay on as Mexico manager despite Copa humbling|
|Tottenham complete Wanyama signing|
|Claridge: England are misusing Jamie Vardy|
|Marseille complete double swoop|
|Wales v Northern Ireland: Evans eager to prolong Irish dream|
|Underdog heroics justify UEFA´s bulkier Euros|
|Atletico Madrid president confirms Vrsaljko move|
|Rejecting Arsenal a ´mature´ move for Leicester star Vardy - Claridge|
|Switzerland v Poland: Seferovic targets final, Pazdan staying humble|
|Juanfran: Spain can use Atletico´s philosophy|
|´It’s always nice to finish above the English´ - Bale sticks the boot in again|
|Euro 2016´s top five moments so far: Payet cries a river as newcomers steal the show|
|Galatasaray fail in CAS appeal|
|´Nice will forever be in my heart´ - How France legend Just Fontaine kickstarted his career on the C|
|Team of the Euro 2016 group stage: Payet, Perisic join blistering Bale|
|The flop XI of the Euro 2016 group stage: Kane and Ibrahimovic join limp Lewandowski|
|O´Neill delighted with Northern Ireland draw placing|
|Germany optimistic on Boateng fitness|
|Croatia v Portugal: Cacic determined to spring another shock|
|Icelandic strongman Magnusson mocks Portugal´s Ronaldo|
|Noble expects West Ham stay for Payet|
|Petrov joins Villa for pre-season camp|
|´We always score our penalties´ - Hallgrimsson sends warning to England|
|Kalinic expects Croatia to progress|
|Rooney respect for Hodgson´s Slovakia gamble|
|Vardy stays at Leicester: Champions buoyed, but what next for Arsenal?|
|Lafferty backs Northern Ireland to go all the way|
|Elmohamady extends Hull stay|
|Hodgson demands ruthlessness from England to open up Iceland|
|´He was nearly dead six years ago´ - Coleman full of admiration for Duffy|
|Rangers seal Kranjcar deal|
|Iniesta wary of ´powerful´ Italy|
|I wanted to rest Gera - Storck|
|Gera living late career dream after waking from injury nightmare|
|Vardy to stay at Leicester after agreeing new contract|
|Morata still wanted by ´top Premier League clubs´|
|Sigurdsson warns Iceland of danger posed by golf buddy Kane|
|Pekerman furious with referee after Colombia´s Copa exit|
|Euro 2016 is wide open, says Cahill|
|Pizzi hails Chile´s ´winners´ mentality|
|Bjarnason hails team spirit among Iceland friends|
|Coentrao defends Ronaldo: ´Speak now, parrots!´|
|MLS Review: Alberg hat-trick inspires Union, RSL leave it late|
|Conte: I´m not from the moon, I know Spain are good|
|Santos wants more from Ronaldo|
|Colombia 0 Chile 2: Early goals see defending champions into Copa final|
|Martino receives Di Maria boost ahead of Copa final|
|De Gea thanks his critics for motivating him|
|Barca not contemplating Neymar exit|
|Pain before pleasure for Sigurdsson and Iceland´s heroes|
|Lavezzi remains upbeat despite Copa-ending injury|
|Smell of injustice: Swedish player cops farting red|
|Ibrahimovic ´very proud´ of Sweden career|
|Euro 2016 Diary: Germany grab the sunloungers, Benzema on the beach and life through a lens|
|´If you don´t know nothing, keep quiet´ - Deeney responds to speculation|
|Wilmots: Belgium must be more clinical|
|Vote remain and we´ll forgive you for 1966! - German newspaper wade into Brexit debate|
|Hamren: Sweden will never find another Ibrahimovic|
|Conte: Ireland got more than they deserved|
|O´Neill hails Ireland heroes|
|Hazard: Ibrahimovic not done yet|