Arturo Vidal made his return from knee surgery as Chile overcame Northern Ireland 2-0 in a friendly on Wednesday.
The Juventus star, who underwent surgery in early May, came on in the 77th minute at the Estadio Elias Figueroa Brander in Chile's final friendly before their FIFA World Cup campaign begins.
Alexis Sanchez also came off the bench and set up both goals as substitutes Eduardo Vargas and Mauricio Pinilla netted late on after Jorge Sampaoli's men looked short of ideas until their introductions.
The win was Chile's 10th straight at home and extended Northern Ireland's winless run to eight matches.
Mauricio Isla, Marcelo Diaz and Gary Medel were the only players to keep their spots in Chile's starting XI which claimed a come-from-behind win over Egypt.
For the Northern Ireland team edged by Uruguay, Niall McGinn and the ill Chris Baird made way for brothers Conor and Ryan McLaughlin.
It was the latter who fired the game's first shot, testing second-choice Mexico goalkeeper Johnny Herrera from range.
Chile were the dominant side in terms of possession, pushing Michael O'Neill's men deep, but they lacked creativity.
Several neat moves were completed by hopeful balls into the box, while the visitors looked most dangerous from set-pieces.
Herrera was forced into a diving save to his right in the 21st minute, punching away Conor McLaughlin's header from a Shane Ferguson set-piece.
A frustrated Chile lost patience and started trying their luck from range as Jorge Valdivia, Fabian Orellana and Diaz had efforts, with only the latter needing Roy Carroll's intervention.
Isla looked dangerous on the right, regularly cutting inside to set up his team-mates for passing or shooting opportunities.
Yet as Chile struggled to test Carroll, Herrera was called into action again six minutes before half-time to save Oliver Norwood's 30-yard free-kick.
The hosts continued to enjoy more of the ball after the break and went closest to opening the scoring in the 58th minute.
Valdivia's attempted cross was headed for the top corner, but a scrambling Carroll tipped the effort around his post.
With the introductions of Sanchez and Vargas came more energy, and Chile almost made it 1-0 in the 64th minute.
Medel's header from a corner found Valdivia at the back post, but the Palmeiras midfielder could only nod his effort against the woodwork.
Diaz forced Carroll into a diving save in the 71st minute, while Sanchez almost scored via a fortunate deflection moments later.
Vidal was introduced to a huge cheer and involved in the game's first goal in the 79th minute.
He found Sanchez with a short pass and the Barcelona attacker's delightful chipped ball was headed in by Vargas, who appeared to be in an offside position as he netted his third goal in two games.
Sanchez made it five assists in two games, turning his man before feeding through Pinilla to finish neatly through Carroll's legs just three minutes later.
The result will give Sampaoli's men confidence ahead of their clash against Australia on June 13.
|Coach: J. Sampaoli|
for C. Carmona 59'
for F. Orellana 59'
for E. Paredes 60'
for G. Medel 77'
for J. Valdivia 77'
for M. Diaz 85'
|Neymar will break my record anyway - Kaka|
|Chile v Brazil: Dunga aware of qualifying difficulties|
|Wanyama has ´forgotten´ about failed Tottenham move|
|United won´t end up like Liverpool - Beckham|
|Bolivia v Uruguay: Tabarez wary of La Paz altitude|
|Cabaye unsurprised by Martial talent|
|Enyeama rift just a ´misunderstanding´|
|´I´m ready to go´ - Bale|
|Osorio set to take charge of Mexico|
|Lewandowski expects to be targeted by Scotland|
|Kramaric frustrated with Leicester role|
|Fowler: I´d love to join Klopp at Liverpool|
|Nigeria v DR Congo: Visa chaos undermines friendly|
|Ramos: Benitez can speak to me about penalty|
|Portugal v Denmark: Ronaldo & Co on the brink of Euro 2016 finals|
|You can´t build a team around Ronaldo - Cruyff|
|Germany without Podolski for final qualifiers|
|Bosnia hopeful Dzeko can face Wales|
|Sevilla rule out move for United outcast Valdes|
|Kovacic criticises distant relationship with Mancini|
|England call up Walker, Townsend as Stones drops out|
|Amalfitano released by West Ham|
|Torres defends Benitez over ´defensive´ jibes|
|Beckham predicts Premier League return for Ancelotti|
|Cabaye relishing competition from Diarra|
|Dybala is already a star - Martino|
|Bayern and Germany legend Muller suffering from Alzheimer´s|
|Diarra thanks Deschamps for France recall|
|Scotland v Poland: Newcomer Shinnie boosted by confidence in Strachan´s squad|
|Doumbia rules out Roma return|
|France v Armenia: Deschamps has faith in Giroud|
|Cruyff critical of Van Gaal and Mourinho|
|Kuwait v South Korea: Perfect records on the line|
|Sneijder: Netherlands face two finals to reach France|
|Beckham backs Giggs as future Manchester United manager|
|Northern Ireland v Greece: Norwood confident of qualification|
|Jovetic slams ´absurd´ injury reports|
|Keane slams Sunderland hierarchy after Advocaat exit|
|Republic of Ireland v Germany: Gundogan doesn´t want to play for a draw|
|Beckham reflects fondly on relationship with Ferguson|
|Tax charges dropped against Messi|
|Gundogan: Klopp would be a great fit for Liverpool|
|´He didn´t have the baby´ - New father Keane expected to line-up for Ireland|
|Bertrand eager to state England case|
|Nedved warns Pogba: You can´t have everything|
|Sakho: I was like a caged lion on the sidelines|
|Honda hits back at Mihajlovic: There´s no point in blaming the players|
|Tottenham´s fitness too much for opponents - Dier|
|Ramos withdraws from Spain squad due to shoulder injury|
|Gundogan and Boateng praise in-form Muller|
|Janmaat ruled out of Netherlands qualifiers|
|Benitez: Defensive? My Napoli team scored 104 goals!|
|Ronaldo not untouchable and will be rested, says Benitez|
|Barca, Madrid and United are Bayern´s Champions League rivals - Effenberg|
|Neymar will stay at Barcelona for his ´entire life´ - Robert|
|Klopp would deliver at any club - Can|
|O´Neill: I didn´t prostitute myself for Grealish|
|Mourinho burning out his players - Capello|
|Lewandowski´s stunning form ´does not make Poland a better team´|
|Barcelona are looking at January signings, confirms Robert|
|Deschamps: I won´t sub Benzema|
|Chung Mong-Joon expects FIFA suspension|
|Mourinho: Ferguson knew I didn´t want United job|
|Ferguson´s hairdryer treatment inspired players – Ronaldo|
|Jordan v Australia: Visitors ready for tough trip|
|Falcao confident of Chelsea turnaround|
|Syria v Japan: Top spot up for grabs|
|Euro giants are scared of playing Wales - Coleman|
|Benzema must convert more chances - Benitez|
|Nasri happy for future without France|
|Van Persie situation concerns Blind|
|Walcott almost unstoppable - Coquelin|
|Bale named as Wales player of the year once more|
|Rojo latest player ruled out of Argentina qualifiers|
|Rooney underwhelmed by Capello as England manager|
|Martial keen to play down ´new Henry´ tag|
|Watzke dismisses Dortmund´s Bundesliga prospects|
|Deschamps calls for Pogba improvement|
|Totti steps up injury rehab|
|Watzke talks up ´great coach´ Klopp amid Liverpool rumours|
|Del Bosque calls up San Jose, Etxeita and Gaspar after injury setbacks|
|Cech happy to see Sanchez back up to top speed|
|Swiss authorities reject FIFA official´s extradition appeal|
|Casillas impressed by ´fantastic´ Navas|
|Rodgers expects transitional Liverpool to improve following sacking|
|Mourinho charged by FA|
|Messi´s absence no excuse for Argentina - Mascherano|
|Deschamps praises Martial for tackling doubters over United move|
|Inter have faith in Mancini - Zanetti|
|Romero accepts number two status behind De Gea|
|Lokomotiv Moscow charged with ´racist behaviour´|
|Deco: Ronaldo dedication borders on sickness|
|Conte calls for Balotelli consistency after Berardi blow|
|Mata: United unacceptable at Arsenal|
|Carvajal blow for Spain as Real confirm ankle injury|
|Xavi wants Barcelona return|
|Bayern can be super successful this season - Effenberg|
|´Stop e-mailing about Muller´ - Rummenigge warns Manchester United|
|Chile are not favourites against Brazil - Jefferson|
|Lewandowski success down to absence of Robben and Ribery - Beckenbauer|
|Deco: Mourinho playing games with the media|
|Pauleta challenges Ibrahimovic to deliver Champions League for PSG|
|Ched Evans case referred to Court of Appeal|
|Pardew hails ´lieutenant´ Cabaye|
|Mourinho receives Chelsea backing|
|Neymar must not focus on replacing Messi - Juninho|
|Insigne warns against Maradona comparisons|
|Navas: Research helped me save Griezmann penalty|
|Benzema unhappy with substitution|
|Mertesacker hails Sanchez and Ozil|
|Struggle against relegation ´not my cup of tea´ - Advocaat|
|We are behind De Boer - Bazoer|
|Ibrahimovic: I want to continue making history at PSG|
|Beckenbauer: Bayern and Guardiola are a perfect fit|
|Carrick: Manchester United will come back stronger|
|Redknapp plays down Sunderland talk|
|Lacazette replaces Ntep in France squad|
|Aguero on par with Messi and Suarez, says Zabaleta|
|"Special" Klopp perfect for Liverpool - Redknapp|
|Dybala: Juventus must improve defensively|
|Kaka replaces Coutinho in Brazil squad|
|Cazorla: Arsenal´s changed mentality made the difference|
|A-League Preview: Victory the team to beat in bid for back-to-back titles|
|Gervinho favouritism talk ´nonsense´ - Garcia|
|Benitez explains Benzema substitution|
|Klaassen, Promes withdrawn from Dutch squad|
|MLS Review: Galaxy, Dallas into play-offs|
|Aguero at Messi, Ronaldo level - Pellegrini|
|Sampdoria ´could´ve won 11-1´ - president Ferrero|
|Mihajlovic: I will not resign|
|Derby draw a good result - Benzema|
|I´ll quit if the players don´t trust me - Mourinho|
|Simeone disappointed not to claim derby victory|
|Blanc not surprised by record-breaking Ibrahimovic|
|Serie A Review: Fiorentina out in front as Napoli thump Milan|
|Benitez rues dropped points|
|Allegri: No crisis at Juventus|