Manchester United prevailed 5-3 on penalties against Inter in Tuesday's International Champions Cup clash in Maryland.
After the teams could not be separated in regulation time - with the score locked at 0-0 - penalties determined the winner and it was United who prevailed at FedEx Field.
Captain Darren Fletcher stepped up and converted the winning penalty after Marco Andreolli's effort cannoned off the crossbar.
The result preserved United's perfect record in the United States, with three wins from three.
Manager Louis van Gaal made four changes to the starting XI that took to the field in the 3-2 victory over Roma on Saturday, with Anders Lindegaard, Chris Smalling, Fletcher and Ashley Young returning to the line-up for their reunion with former United captain Nemanja Vidic.
Inter made just one change to the team that beat Real Madrid on penalties in California on Saturday, with Joel Obi dropping out for Rene Krhin.
A number of United youngsters were given game time in Denver but the return of senior personnel was clearly a boost and it showed with the Premier League outfit coming close to breaking the deadlock in the 10th minute.
United defender Phil Jones stooped low to direct his header towards the bottom corner of the net but Inter goalkeeper Samir Handanovic got his hand to the ball and denied Jonny Evans on the rebound in a goal-mouth scramble.
There were few clear-cut chances throughout the first half, though some neat interchange play between Wayne Rooney and Juan Mata almost resulted in the opening goal, but the Inter defence were up to the task.
Wilfred Zaha was the only player in United's travelling squad not to have played a minute prior to Tuesday's clash but he was given time in the second half and came close to netting the opener within minutes of his introduction after a driving run from halfway.
Inter almost won it at the death after being awarded a free-kick, however David de Gea denied Fredy Guarin from 25 yards out as the match headed to penalties.
United would not be denied a third successive victory in the USA, albeit after a shoot-out, and will now turn their attention to Saturday's clash with Real Madrid.
Inter are back in action against Serie A rivals Roma on the same day.
|Mignolet: Liverpool in better position to win title than in 2013-14|
|Giroud wants Premier League title but understands China temptations|
|Tianjin forced to scrap moves for Costa, Benzema, Cavani and Falcao|
|My goal was better than Mkhitaryan´s - Giroud|
|Pochettino not interested in Argentina job|
|Kane: Tottenham can win Premier League|
|Corinthians dreaming of Drogba - Paulo Roberto|
|Coutinho calls for Liverpool focus|
|Chiellini compares Pogba to LeBron and Bolt|
|Maradona to become Napoli ambassador|
|Mihajlovic furious after Torino collapse|
|Icardi has offers from China - Wanda Nara|
|Pogba can cope with pressure - Ibrahimovic|
|´My half-time words will stay in the dressing room´ - Montella annoyed with AC Milan|
|Juventus unveil dramatic change to club logo - but not everyone´s a fan|
|´I do not think I will return to coaching´ - Van Gaal set to call it quits|
|Torino 2 AC Milan 2: Bacca caps thrilling comeback as hosts pay the penalty|
|DR Congo 1 Morocco 0: Kabananga pounces on blunder to give 10 men the points|
|´Happy and comfortable´ Sanchez dismisses Arsenal exit talk|
|How much?! West Ham flop Simone Zaza could cost Valencia €20m|
|Mali v Egypt: Salah leads Pharaohs´ bid for AFCON glory|
|Sevilla concede they ´cannot force´ sporting director Monchi to stay|
|Ivory Coast 0 Togo 0: Reigning champions held to opening draw by Adebayor and co.|
|Goalkeeping woes, Stones and tactical confusion - How Guardiola is making life difficult for himself|
|Ozil and Sanchez can be persuaded to stay - Cech|
|Pogba: I rejected Barcelona and Real Madrid|
|Ghana v Uganda: Gyan dreams of first trophy since 1982|
|Chiellini: Juventus a work in progress|
|Robben agrees Bayern renewal until 2018|
|Hazard: Goals do not matter to me|
|Bennell pleads not guilty to eight child sex offences|
|Muller fed up with debate over Bayern role|
|Wenger glad Sanchez is not ´a Costa problem´|
|Flick resigns as DFB´s sporting director|
|Gomis ´can´t wait´ to welcome Payet to Marseille|
|Chinese FA changes foreign player rules after ´irrational´ spending|
|Like father, like son: Justin Kluivert follows in dad´s footsteps|
|´No reason to lose him´ - Marotta rubbishes talk of Allegri exit|
|Courtois: We don´t need Costa|
|Kane: Tottenham players won´t go to China|
|Noble ´angry and disappointed´ with Payet|
|Klopp furious over Matip uncertainty|
|Wenger surprised by tight Premier League|
|´Money is not everything´ - Conte issues warning amid China speculation|
|Fiorentina defeat a ´bad setback´ - Allegri|
|´This will elevate this group of players´ - Sampaoli revels in Sevilla late show|
|WATCH: Rio Ferdinand screams and dances in crazy Man Utd celebration|
|Real Madrid relaxed, admits Zidane after Sevilla defeat|
|Monaco go top of Ligue 1 with stunning Marseille victory|
|Ronaldo equals LaLiga penalty record as Real Madrid lose|
|Sevilla 2 Real Madrid 1: Stunning late comeback ends unbeaten run at 40|
|Fiorentina 2 Juventus 1: Brilliant Viola breathe life into Serie A title race|
|Tunisia 0 Senegal 2: Mane on target as favourites start strongly|
|Mourinho explains Klopp confrontation|
|Klopp delights in Alexander-Arnold display|
|Algeria must cut out mistakes against Tunisia - Leekens|
|Long balls led to Man Utd equaliser, says Klopp|
|´We attacked, Liverpool defended´ – Mourinho insists a point flattered Klopp´s men|
|DR Congo v Morocco: ´Confidence´ the Atlas Lions´ biggest hindrance ahead of AFCON opener|
|Ibrahimovic: Direct tactics worked for United|
|Guardiola rues gap to Chelsea after Goodison mauling|
|Algeria 2 Zimbabwe 2: Mahrez double prevents shock defeat|
|Manchester United 1 Liverpool 1: In-form Ibrahimovic saves hosts|
|Ivory Coast v Togo: AFCON champions hope to tame Le Roy´s ´troublemakers´|
|Guardiola lays City´s mental frailties bare after Goodison rout|
|Koeman hails ´perfect´ Everton after City mauling|
|Nice stalemate gives Monaco chance to go top|
|Guardiola suffers heaviest league loss in Everton thrashing|
|Neymar-esque Zaha is England´s loss – Bolasie|
|Everton 4 Manchester City 0: Koeman leaves old pal Guardiola´s title bid in tatters|
|Matip withdrawn from Liverpool selection over eligibility questions|
|Podolski staying at Galatasaray, insists sporting director|
|Cavani wants PSG stay|
|Torino move feels normal now – Hart|
|Chinese FA changes rule on CSL foreign players - reports|
|Bayern complete swoop for Hoffenheim duo Sule and Rudy|
|Aubameyang: Dortmund not really like Barca, Madrid or Bayern|
|Pogba can chance a game in one second - Herrera|
|Newcastle Jets 2 Perth Glory 2: Keogh´s eighth of season seals draw|
|Klopp: Liverpool ready for Old Trafford test|
|Herrera taunts Liverpool ahead of Old Trafford showdown|
|I had to be 100 per cent to stay at Boca - Tevez|
|No player is bigger than the club - Carroll takes swipe at want-away Payet|
|Icardi: I can always move to China at end of career|
|Mkhitaryan: Klopp convinced me not to join Liverpool|
|Mourinho: Pogba can score every game|
|Cameroon´s profligacy frustrates Broos|