Hull City will make their first foray into Europe when they face Slovakian side Trencin in the UEFA Europa League on Thursday.
The Premier League club have waited a long time for their maiden continental adventure and they will be expected to mark their first competitive fixture outside the UK with a victory.
Hull played in their first major final when they were beaten by Arsenal in the FA Cup showpiece at Wembley in May and qualified for the Europa League as a result.
Boss Steve Bruce admitted competing in Europe can be a "huge complication" due to the number of games they will play if they qualify for the group stage, but embraced the prospect of becoming the first manager to lead Hull into a European fixture.
The 2013-14 campaign was one to savour for Hull fans, as they preserved their Premier League status in their first season back in the top flight as well as enjoying trips to Wembley for the semi-final and final for the FA Cup.
And they will be determined to start the new season on a high note against a Trencin side that were runners-up in the Slovakian Super Liga last season and have won their opening two league games of the new campaign.
As well as being a landmark game for Hull, Thursday's fixture will also be Bruce's 100th at the helm and the former Sunderland boss is no doubt his side will be prepared despite a disappointing friendly display against League One Barnsley at the weekend.
He said: "We'll be as ready as what we will be.
"It was a pre-season friendly where nobody could tackle a fish supper, never mind a football, so it was a normal pre-season affair. But make no mistake, we will be better on Thursday.
"When the proper ball comes out for a cup competition, then all of a sudden there's a different mentality."
Trencin withstood a second-leg fightback from Serbian club Vojvodina in the second qualifying round to prolong their participation in the Europa League.
Moses Daddy-Ajala Simon scored a hat-trick as Ivan Vrabec's side coasted to a 4-0 victory in the first leg, but they then suffered a 3-0 defeat in the return fixture as Vojvodina gave them a real scare.
The likes of Robert Snodgrass, Tom Ince, Harry Maguire and Andy Robertson could make their competitive Hull debuts in Slovakia, with Bruce having been busy in the transfer market.
Bruce will monitor the fitness of Alex Bruce (Achilles), Curtis Davies (hamstring), David Meyler (knee) and Allan McGregor (knee).
|Champions League Review: Van de Beek earns Ajax away goal in Nice tie|
|Celtic 0 Rosenborg 0: Unconvincing hosts fortunate to escape with draw|
|Keeping players against their will is counterproductive - Marotta explains Bonucci exit|
|Serie A fixtures: Potential for AC Milan nightmare October as Bonucci faces pre-Halloween Juve reuni|
|Serie A fixtures: Juventus to face gruelling run-in|
|Serie A fixtures: Inter meet AC Milan in October, Derby d´Italia set for December|
|Mourinho: I had to beg Real Madrid to let me go|
|Chelsea captain Cahill: Terry will be first person I call|
|Serie A fixtures: Juventus face Cagliari in opening round|
|Sarr chooses Rennes over Barcelona|
|Terim leaves Turkey role after brawl|
|Bacca left out of Milan squad amid Marseille rumours|
|Zlatan Ibrahimovic bang on the money in latest Instagram post|
|Barkley will 100 per cent leave Everton - Koeman|
|City can challenge Madrid – Sane|
|Fabinho and Lemar staying at Monaco - Vasilyev|
|Mbappe in talks over new Monaco deal|
|Toure urges Mendy to adapt quickly|
|Inter can forget about Vidal - Ancelotti|
|Perisic to Man Utd dependent on Inter finding valid alternative - Spalletti|
|Guardiola refuses to rule out City rivalling Madrid in Mbappe pursuit|
|Bayern Munich as big if not bigger than Real Madrid - James Rodriguez|
|Real Madrid friends reunited: Zinedine Zidane, Raul and David Beckham meet in LA|
|Lure of Pep made it easy for Danilo to choose Man City over Chelsea|
|Man Utd boss Mourinho says ´dangerous´ fees a threat to football|
|Victory star Rojas set to return to Europe|
|Beckham happy for Madrid coach Zidane|
|Toluca 0 Atletico Madrid 0: LaLiga giants held to dour draw|
|Tottenham 2 Roma 3: Kolarov makes debut in thriller|
|Premier League spending unsustainable – Levy|
|Mourinho: I miss Rooney a lot|
|Instagram post was Pique´s ´gut feeling´ over Neymar future|
|Emery unmoved when quizzed on PSG´s pursuit of Neymar|
|Real Madrid´s attack doesn´t need Mbappe to wreak havoc, claims Casemiro|
|Balotelli fitter than last season, warns Dante|
|Mata and Herrera provide Manchester United injury boost|
|Orlando capture Dwyer in record swoop|
|Bardsley bolsters Burnley backline options|
|Ibrahimovic still a leader at Old Trafford – Pogba|
|Thiago Maia joins Brazilian influx at Lille|
|WATCH: Neymar´s aim defeats Messi and Suarez|
|Hart can help West Ham reach top eight – Hislop|
|Ajax´s Nouri out of intensive care and breathing unaided|
|Mourinho wants a midfielder and winger at Man Utd|
|Mourinho slams UEFA over Bailly ban|
|Payet was a flawed individual – Sullivan|
|Conte pleased with Morata cameo|
|Kaka uncertain of Orlando future as he targets MLS play-offs|
|Cassano should be applauded, says Prandelli|
|Sanches seeking to swap Munich for Milan|
|Brown loaned to Brighton after signing Chelsea contract|
|VAR would have ruled out ´Hand of God´ goal, Maradona admits|
|Bordeaux abandon Wellington Silva transfer|
|Kaka backs Bonucci to help Milan rediscover glory days|
|Chelsea 2 Bayern Munich 3: Muller at the double as Bayern bounce back|
|Injured Michu confirms retirement|
|Neymar will make right decision amid PSG links - Kaka|
|Wagner backs Liverpool to win the league|
|Monaco deny world-record €180m Real Madrid deal for Mbappe – report|
|Higuain: I need to score more in Europe|
|Real Madrid ´would be alright´ but Dolberg in no rush to leave Ajax|
|Mane, Ings back in full Liverpool training|
|Mahrez would do great things at Roma – Gonalons|
|Real Madrid want a top-class French striker, Lyon president claims|
|Bernat has surgery on ankle ligament tear|
|Higuain wants Dybala at Juventus but ´can´t point a gun at his head´|
|I want more trophies – Ronaldo confirms Real Madrid stay|
|Aulas: PSG signing Neymar for record fee is risky|
|Klopp unfazed by Mourinho, Man United|
|WATCH: Mourinho crashes Lingard interview|
|Lukaku aiming to emulate Ronaldo at Man United|