The returning Robin van Persie overshadowed Juan Mata on his debut as Manchester United claimed a comfortable 2-0 victory over Cardiff City.
Spain international Mata was given his first outing in a United shirt since completing his club-record £37.1million deal from Premier League rivals Chelsea on Saturday, but it was Van Persie - making his first appearance since December 10 due to a groin injury – who stole the show by notching the opener.
Mata played his part in a lively United performance, and he was afforded a standing ovation by the Old Trafford crowd as he was withdrawn in the closing stages, with Ashley Young's superb strike rounding off a pleasing night for boss David Moyes.
Cardiff manager Ole Gunnar Solskjaer, who enjoyed an 11-year spell as a player at United, could not spoil the party against his former club - the Norwegian enduring an unhappy homecoming as he continues to search for his first Premier League victory in charge.
The home side controlled the tempo in the first half and deservedly moved ahead when Van Persie scored his fifth goal in his last six Premier League games with a close-range header.
United continued to impress and Young added a second with a fierce strike just short of the hour mark, as United surpassed 1,000 points at Old Trafford in the Premier League.
United utilised Mata behind Van Persie, while Wayne Rooney was on the substitutes' bench after a five-match lay-off with a foot injury.
As well as welcoming back Solskjaer, there was another familiar face for United fans in the Cardiff line-up, as they named former Old Trafford striker Fraizer Campbell in their starting XI.
The home side were rewarded for a bright start with the opener after six minutes.
Antonio Valencia headed Young's teasing delivery against the crossbar and, although David Marshall saved Van Persie's initial follow-up, the Dutchman nodded home the rebound.
Mata was at the heart of all United's attacking play but, despite their solid start, it took until the 34th minute for the champions to fashion another chance of note when Patrice Evra's clever backheel found the lively Van Persie, who flashed an effort across goal from an acute angle.
Cardiff could have punished the hosts when Craig Noone crossed from the right, only for his delivery to narrowly evade Campbell.
The visitors enjoyed a spell of pressure after the break and Declan John's cutback only just escaped the attentions of Campbell again.
United were rarely in danger, however, and Young made it 2-0 on 59 minutes when he received the ball on the left before cutting inside and skipping past two challenges to rifle into the far corner from 25 yards.
Shortly afterwards, Rooney replaced Van Persie - and he was soon among the action with a deflected effort sailing narrowly wide.
Valencia then saw Marshall tip his effort onto the post as United piled on the pressure.
Mata saw an effort deflected over before he was withdrawn with time running out, receiving the adulation of his new fans.
Rooney then curled wide from 20 yards in injury time but United had done enough.
|20||R. van Persie||6'|
|Coach: D. Moyes|
for R. van Persie 63'
for R. Giggs 71'
for Mata 84'
|Nacho´s goal better than my Champions League final volley - Zidane|
|Borussia Dortmund 1 Union Berlin 1 (aet, 3-0 pens): Weidenfeller shootout heroics seal progress|
|Bilic: Crowd trouble distracts from great West Ham win|
|Kompany told me he couldn´t play anymore - Guardiola|
|Liverpool and Manchester United handed home quarter-finals|
|Inter 2 Torino 1: Icardi double alleviates pressure on De Boer|
|Manchester United 1 Manchester City 0: Mata extends Guardiola´s winless run|
|West Ham 2 Chelsea 1: Crowd trouble tarnishes Hammers´ route to quarter-finals|
|Cultural Leonesa 1 Real Madrid 7: Morata and Asensio star in BBC´s absence|
|Bayern Munich 3 Augsburg 1: Green´s first goal sends holders through|
|Juventus 4 Sampdoria 1: Rapid start sets champions on their way|
|Crafty Suarez is world´s best striker - Godin|
|Mancini: Balotelli has wasted years but can bounce back|
|Rami rejected ´risky´ PSG move|
|Neymar would have cost PSG €430m, claims father|
|Sacchi warns Bayern players over Ancelotti temper|
|Valencia ´pleased´ with RFEF bottle ruling|
|Mourinho apologises to Utd fans for Chelsea thrashing|
|Barcelona lash out at ´totally reprehensible´ RFEF comments|
|Jacob leaves Marseille amid rumours of Zubizarreta appointment|
|Lavezzi added to Argentina squad as Dybala drops out|
|Del Bosque: Mourinho had a point on Conte|
|N´Zonzi in talks over Sevilla extension|
|Allardyce successor ´will not be a mercenary´ - Glenn|
|Aubameyang like a rocket, Lewandowski perfect - Riedle|
|RFEF fines Valencia, warns Barca over bottle incident|
|Wenger tells Iwobi to improve his finishing|
|Barcelona without Mathieu for three weeks|
|Kimmich draws inspiration from Xavi|
|Vazquez signs new Madrid deal|
|Higuain the best striker in the world - Nedved|
|Wolfsburg regret De Bruyne, Perisic sales|
|Parejo slams Neymar for ´inciting´ Valencia fans|
|Gundogan predicts ´very lively´ Manchester derby|
|Luis Enrique satisfied with Supercopa workout|
|Messi could join Newell´s after World Cup - Maxi Rodriguez|
|Ibrahimovic wants United to be the boss of City|
|Schmidt on the bus as Lotte book ticket for next round|
|Pogba still adapting to Premier League, says Mourinho|
|Southgate hails influence of demoted Rooney|
|Lille ready to heap more pressure on PSG as Corchia dreams big|
|I´m among top 20 LaLiga coaches, jokes Luis Enrique|
|Brattan earns Socceroos call-up|
|Pochettino pleased with Janssen|
|Klopp never questioned Sturridge quality|
|Barcelona downed by Espanyol in Supercopa|
|Heavy Milan defeat ´just a bump in the road´ - Montella|
|Pochettino wanted Liverpool debutant sent off|
|Klopp happy to entertain as Liverpool youngsters earn their spurs|
|Leverkusen dumped out by 10-man minnows|
|Wenger praises Oxlade-Chamberlain work ethic|
|Wenger praises Oxlade-Chamberlain work ethic|
|Tuchel unaffected by Real Madrid rumours|
|I would like to pick Toure, believe me - Guardiola|
|Genoa 3 AC Milan 0: Unbeaten run comes crashing to an end as Paletta sees red|
|Liverpool 2 Tottenham 1: Sturridge at the double to book quarter-final spot|
|Arsenal 2 Reading 0: Oxlade-Chamberlain brace secures safe passage|
|Football world mourns Carlos Alberto|
|81 per cent win ratio and more goals than Bayern Munich - Two years of Messi, Suarez and Neymar|
|Ridgewell reportedly arrested for drink driving|
|Verratti not leaving PSG - agent|
|Costa competition benefitting Batshuayi, says Conte|
|Pele hails ´friend and brother´ Carlos Alberto|
|Bailly confirms two-month lay-off|
|How Carlos Alberto established his legacy as one of the greats|
|Allegri hints at Marchisio return|
|Lewandowski has not renewed with Bayern - agent|
|Carlos Alberto: Capita´s World Cup triumph in numbers|
|Hull´s Snodgrass out for a month|
|Keita reveals Arsenal, Manchester City, Liverpool snub|
|Mikel not giving up on Chelsea career|
|Former Brazil captain Carlos Alberto dies|
|Guardiola wants to help ´special player´ Aguero|
|Roma welcome back Strootman, Rudiger for Sassuolo clash|
|Wolves confirm Zenga dismissal|
|Bruce lauds Rooney as a world ´great´|
|Raiola made €27m on Pogba move, reveals Juventus director|
|Dortmund injury woes worsen with Aubameyang|
|De Bruyne out of Manchester derby|
|Conte: I always show respect to opponents|
|FIFA fines RFEF over Madrid, Atletico breaches|
|Pedro backs Conte amid Mourinho spat|
|Big clubs would fight for Edwards if he was Brazilian - Pochettino|
|They boo Ronaldo, they booed me as well - Zidane|
|De Boer fed up of sacking talk|
|Neuer: Bayern have no room for error|
|Bilic praises Conte´s ´aggressive´ demeanour|
|Di Maria will bounce back - Motta|
|EFL opens investigation into Watford over ´forged´ bank letter|
|Hummels admits RB Leipzig a serious threat for Bayern|
|Pedro reveals Barcelona talks|
|De Bruyne: I have no problem with Mourinho|
|Casillas: I have not retired from Spain duty|
|Raul backs under-fire Ronaldo for Ballon d´Or glory|
|Mourinho and United must lower expectations - Xavi|
|Hands off! Milan CEO insists Donnarumma will stay|
|Glory coach Lowe accepts ban|
|Scolari extends contract with Guangzhou Evergrande|
|Guardiola eliminated City doubts - De Bruyne|
|Klopp lauds Ings for ´perfect´ response|
|Wenger: Perez needs to take chance|
|Boys to men: Mourinho challenges United players|
|Kompany committed to bargain with City medics|
|´Insipid´ Hazard overlooked for Ballon d´Or|