Arsene Wenger admits Arsenal's FA Cup draw against Liverpool has made a tough fixture list in the second half of the season even harder.
Arsenal will face Liverpool twice, as well as Manchester United and Bayern Munich, in the space of11 days during February, while March sees them take on Bayern, Tottenham, Chelsea, Manchester City and Everton.
Wenger remains positive his players can cope with the pressure of such tests, but knows rotation will be vital to ensure his squad remain injury-free.
"It's an interesting draw (against Liverpool) and a difficult one, (but) we have a little advantage by playing at home," he said on Monday.
"There will be plenty of big games, which means whole squad needs to be highly focused.
"It is a massive challenge, but I am confident we can do that (succeed).
"It's very important I get it right on the rotation front."
The Frenchman received a boost ahead of Arsenal's Premier League clash with Southampton on Tuesday, with the return of Aaron Ramsey, Mikel Arteta and Thomas Vermaelen, while Alex Oxlade-Chamberlain may be ready for his first start since the opening day of the season.
The league leaders travel to St Mary's looking to record an eighth consecutive victory in all competitions, but Wenger knows doing so will be a tough ask against Mauricio Pochettino's side.
"Everybody goes to Southampton now knowing they are in for a very difficult game," he added.
"He (Pochettino) has done a very good job because nobody knew him when he came here.
"Southampton have done a remarkable job with their academy. The quality of their work is amazing.
"We have a doubt about Wilshere but Ramsey, Arteta and Vermaelen are back in the squad.
"He (Oxlade-Chamberlain) is not fully fit but he is getting closer. I haven't decided whether he will start tomorrow."
|Coach: A. Wenger|
for L. Podolski 69'
for A. Oxlade-Chamberlain 75'
for Y. Sanogo 88'
|UEFA Champions League Review: Ajax crash out after home defeat|
|Blackpool handed suspended deduction|
|Bayern Munich 3 Milan 0: Guardiola and De Jong lock horns in tunnel|
|Akpom, Ojo and Solanke on the move|
|McClaren: No Newcastle bid for Austin|
|Real Madrid 2 Tottenham 0: Bale on target against former club|
|Mangala vows to improve on debut campaign|
|Tomlin completes Bournemouth switch|
|Astra v West Ham: Page hungry for first-team action|
|Di Maria arrives in Qatar for PSG medical|
|Vitesse v Southampton: Caulker prepared to wait for his chance|
|UEFA rejects Fenerbahce´s Fred appeal|
|Watford show support for assaulted fan as police charge six|
|Ibrahimovic to miss PSG opener|
|Klopp suited to Bayern job - Watzke|
|Eredivisie season-opener postponed due to police strike|
|Dortmund v Wolfsberger: Tuchel set for home bow|
|Griezmann at the double in Atletico win|
|Japan v South Korea: Halilhodzic calls for ´pride´|
|Mourinho enjoying improved relationship with Abramovich|
|Gradel agrees Bournemouth return|
|Inter switch an ´easy decision´ for Miranda|
|Bojan eyes early comeback|
|Vitesse hopeful over Solanke loan deal|
|Pedro will decide his own future - Luis Enrique|
|Iniesta handed Barcelona armband|
|Kukesi punished after Europa League abandonment|
|Leno hints at Leverkusen exit|
|Benitez explains Ronaldo absence|
|Pochettino backs Kane to be among world´s best|
|Messi not ruled out of Mexico friendly - Martino|
|China v North Korea: Kim´s side look for another win|
|River Plate v Tigres UANL: Copa Libertadores final evenly poised|
|Real target Ceballos focused on Betis - Mel|
|Torres: I´d give my life to win La Liga with Atletico|
|Platini can lead FIFA change - Fernandez|
|Mel: Betis won´t be signing Osvaldo|
|Ferrero defends Samp boss Zenga|
|Pochettino expects Spurs improvement|
|Bale ideal for United - Robson|
|Ferdinand: Di Maria will regret United failure|
|Benitez pleased with goalkeepers as De Gea transfer saga continues|
|Guardiola tips fit Schweinsteiger to shine|
|Confident Oxlade-Chamberlain hits back at Keane|
|Ferdinand: Stones would be ´a lunatic´ to join Chelsea|
|Qarabag v Celtic: Gordon wants positivity from Scottish champions|
|Higuain rejects extension from Napoli|
|Zamora returns to Brighton|
|West Ham can cope without Valencia - Gold|
|Wickham loses on Palace debut|
|Guardiola: No problem with Matthaus and Effenberg comments|
|Cartabia excited by Deportivo loan|
|Lyon confirm Rafael deal|
|Hysaj agrees deal to follow Sarri to Napoli|
|Rafael says his goodbyes to Manchester United|
|Dos Santos ready to get going with Galaxy|
|Pochettino rejects Soldado exit talk|
|Metatarsal misery for Mulumbu|
|Benitez: Benzema and Bale going nowhere|
|Mihajlovic: Ibrahimovic would make Milan title contenders|
|Hughes not taking any risks with Bojan|
|Guardiola relishing Audi Cup test|
|Di Maria ´taking a step up´ - Silva|
|Leicester bring in defender Benalouane|
|Deulofeu doubtful for Premier League opener|
|West Ham striker Valencia out for three months|
|UEFA: Qarabag-Celtic to go ahead|
|Palace seal Wickham swoop|
|Ronaldo and Benzema to miss Audi Cup|
|Marotta: Juventus could lose Pogba|
|Kante completes Leicester switch|
|Khedira ruled out for two months|
|FA accepts Mourinho criticism of Wembley surface|
|Robben rubbishes injury talk|
|Marchisio expects Milan title challenge|
|Rafael set for Lyon move|
|Celtic ´seeking reassurances´ over Qarabag pitch|
|Wenger beating Mourinho does not affect Chelsea - Zouma|
|Rooney moved by Everton welcome|
|Mancini not worried by lack of Inter goals|
|Coloccini wants to finish career at Newcastle - McClaren|
|Ramsey: Pressure to win trophies is nothing new|
|Terry: Wembley defeat could be a ´blessing in disguise´|
|Blatter not running for IOC re-election|
|Bendtner: Wolfsburg can challenge Bayern for Bundesliga honours|
|Liverpool relishing Britannia return, says Henderson|
|Everton big enough to keep Stones - Martinez|
|MLS Review: Fire stun Dallas as goals dry up|
|New Atletico signings excite Raul Garcia|
|Cahill expects Arsenal title challenge|
|Jovetic happy with Inter debut|
|Luis Enrique: Barca defence must improve|
|Yanev calls for calm after ugly scenes in friendly|
|Coppa Italia Review: Cittadella romp to victory, Brescia rely on penalties|