Arsene Wenger admits Arsenal's FA Cup draw against Liverpool has made a tough fixture list in the second half of the season even harder.
Arsenal will face Liverpool twice, as well as Manchester United and Bayern Munich, in the space of11 days during February, while March sees them take on Bayern, Tottenham, Chelsea, Manchester City and Everton.
Wenger remains positive his players can cope with the pressure of such tests, but knows rotation will be vital to ensure his squad remain injury-free.
"It's an interesting draw (against Liverpool) and a difficult one, (but) we have a little advantage by playing at home," he said on Monday.
"There will be plenty of big games, which means whole squad needs to be highly focused.
"It is a massive challenge, but I am confident we can do that (succeed).
"It's very important I get it right on the rotation front."
The Frenchman received a boost ahead of Arsenal's Premier League clash with Southampton on Tuesday, with the return of Aaron Ramsey, Mikel Arteta and Thomas Vermaelen, while Alex Oxlade-Chamberlain may be ready for his first start since the opening day of the season.
The league leaders travel to St Mary's looking to record an eighth consecutive victory in all competitions, but Wenger knows doing so will be a tough ask against Mauricio Pochettino's side.
"Everybody goes to Southampton now knowing they are in for a very difficult game," he added.
"He (Pochettino) has done a very good job because nobody knew him when he came here.
"Southampton have done a remarkable job with their academy. The quality of their work is amazing.
"We have a doubt about Wilshere but Ramsey, Arteta and Vermaelen are back in the squad.
"He (Oxlade-Chamberlain) is not fully fit but he is getting closer. I haven't decided whether he will start tomorrow."
|Coach: A. Wenger|
for L. Podolski 69'
for A. Oxlade-Chamberlain 75'
for Y. Sanogo 88'
|Allardyce confirms Rooney retains England captaincy|
|Hart to join Torino – agent|
|Sanches withdrawn from Portugal squad|
|Sporting CP issue Adrien Silva clarification amid Leicester links|
|Watford confirm Okaka signing|
|Manchester City outcast Zuculini seals Rayo Vallecano loan switch|
|Dembele offers something different - Deschamps|
|Sunderland would just love to get rid of me - Lens|
|No Casillas in Spain squad represents a ´new era´, says Ramos|
|Zenit defender Criscito could return to Italy, claims agent|
|Barcelona reveal Messi hamstring injury|
|Modric named new Croatia captain|
|Napoli announce Rog signing|
|De Boer is building something at Inter - Morratti|
|Keane eyes coaching career after international retirement|
|Bravo left out of Chile squad for family reasons|
|West Brom announce Chadli signing|
|Former Dodgers owner set for Marseille purchase|
|Ferdinand: I reached out to Wenger|
|Holgate has big quality for a young player - Koeman|
|Manchester United want to keep Rojo, says agent|
|Low not concerned by captaincy as Germany bid farewell to greats|
|Aguero pulls out of Argentina squad|
|Howedes: Germany must prove themselves all over again|
|Ventura close to tears on first day of Italy training|
|Torino interested in City outcast Hart|
|Adrien Silva hoping to seal ´exceptional´ Leicester switch|
|Boufal joins Southampton from Lille for club-record fee|
|Villa outcast Lescott joins AEK Athens|
|Milner: I´m learning left-back role as fast as I can|
|Allardyce ready for Hart transfer disruption|
|´Door always open´ for Barkley - Allardyce|
|Xhaka like Petit, claims Wenger|
|Coric: I was a medical away from joining Liverpool|
|Pasalic keen to put injury troubles behind him at Milan|
|Guardiola delighted with Sterling form|
|Rooney should retire from England duty - Shearer|
|Hazard can ´decide´ the title - Ivanovic|
|Allardyce hails ´outstanding´ Antonio|
|Belgium can make history - Henry|
|Nice president: Call Balotelli and tell him we need a striker|
|Modric would like to see out career in Madrid|
|Geromel replaces Caio in Brazil squad|
|Mustafi: Ozil convinced me to join Arsenal|
|Pardew confirms ´one or two´ more signings|
|MLS Review: Kaka brace denies NYC top spot, Timbers beat Sounders|
|Mihajlovic: I won´t waste anymore breath on Maksimovic|
|Okon named Central Coast Mariners coach|
|´Special´ Rashford will get chance - Rooney|
|Injury forces Schurrle out of Germany squad|
|Burke snubs Premier League interest to join RB Leipzig|
|Guardiola: Nasri has a future at City, if he wants it|
|Klopp confident ´all will be good´ with Sturridge|
|Emery confident PSG will bounce back|
|Athletic may strengthen squad - Valverde|
|Fabregas dismisses exit rumours, committed to Conte and Chelsea|
|De Boer encouraged as Inter´s wait continues|
|Barca ´strengthened´ by Luis Enrique´s 100th win|
|Fekir to undergo knee operation|
|Monaco 3 Paris Saint-Germain 1: Ligue 1 champions suffer early loss|
|Aguero facing possible Manchester derby ban|
|Athletic Bilbao 0 Barcelona 1: Rakitic strike extends Barca´s strong start|
|West Ham´s Antonio handed first England call-up|
|Guardiola ´so optimistic´ after Man City´s perfect start|
|Inter 1 Palermo 1: Icardi gets De Boer´s men off the mark|
|Credit Guardiola for boost in form, says Sterling|
|Manchester City 3 West Ham 1: Hosts stay perfect under Guardiola|
|Cavani won´t return to Napoli - De Laurentiis|
|Pulis puts 48-hour deadline on Berahino future|
|Zaza awaits ´new adventure´ at West Ham|
|Karanka open to transfer ´surprises´ after strong Middlesbrough start|
|Dost completes Sporting move|
|Allardyce wanted N´Zonzi for England|
|World Cup could be expanded - Infantino|
|West Brom 0 Middlesbrough 0: Booed Berahino benched for dour draw|
|Gyan´s ´destiny´ in England, Sunderland return an option|
|Zidane wanted Pogba and Madrid are weaker without him - Raiola|
|Juventus end Matuidi pursuit|
|´He´s freaking amazing!´ - Balogun hails Dortmund´s Dembele|
|Thohir thrilled as Inter confirm Joao Mario signing|
|Fabinho expects Monaco stay despite Manchester United links|
|Infantino has Blatter wine cellar removed as part of FIFA reform commitment|
|West Ham seal Zaza loan|
|Joao Mario posts heartfelt thanks to Sporting after record-breaking Inter move|
|Aguero: I´m not competing with Ibrahimovic|
|Mihajlovic: Maksimovic is dead to me|
|Risdon replaces Wright for Socceroos|
|MLS Review: DC United in goal-fest, Impact stun Toronto|
|Schmeichel to undergo surgery|
|Milik revels in ´dream´ brace as he ignores Higuain shadow|
|Rossi to join Celta Vigo|
|Ayestaran: Barcelona target Alcacer unable to compete|
|Simeone: Winless Atletico must remain calm|
|Griezmann: Atletico must improve or face relegation fight|
|Sterling ´feels the love´ at City - Guardiola|
|Stones glad he did not end up at Chelsea|
|James impact earns Zidane´s praise|
|Montella bemoans AC Milan´s indiscipline|
|Leganes 0 Atletico Madrid 0: Returning Griezmann fails to inspire turgid visitors|