The Premier League's top three have been unstoppable of late and third-placed Chelsea will want to maintain that form against West Ham.
Jose Mourinho's men currently share a run of five consecutive league victories with leaders Arsenal, while second-placed Manchester City have won seven in a row, meaning just two points separate the sides in the race for the title.
Chelsea should be full of confidence ahead of Wednesday's meeting with a West Ham outfit who have just one win from their last nine fixtures in all competitions.
The men from east London have not won at Stamford Bridge since 2002, losing seven of the subsequent eight encounters, and suffered a 3-0 reverse when the sides met at Upton Park in November.
Former West Ham favourite Frank Lampard scored a double against his old club on that occasion, breaking the deadlock with a 21st-minute spot-kick before finding the net again late on after Oscar had doubled the advantage.
Chelsea marked Mourinho's 51st birthday with progression to the fifth round of the FA Cup on Sunday, while West Ham should be fresh having had a weekend off thanks to being eliminated by Nottingham Forest in the third round.
And West Ham manager Sam Allardyce knows the magnitude of the task that lies ahead of his side, who are third bottom in the Premier League.
"Stopping Oscar, (Eden) Hazard, (Samuel) Eto'o is one of the elements for us which we have to be very careful of," he said. "When those players get the ball we have to make sure we're very sharp and that we close them down, otherwise their skills and abilities will make life difficult for us."
Fernando Torres (knee) remains sidelined for Chelsea, who could hand a first league start to Nemanja Matic since he returned to the club from Benfica and a debut to Mohamed Salah, signed from Basel on Sunday.
Allardyce, meanwhile, has a near fully-fit squad to choose from, with former Chelsea midfielder Joe Cole and Winston Reid the only players guaranteed to miss out.
As well as his returning players, Allardyce's ranks will be boosted by the arrivals of new signings Marco Borriello and Antonio Nocerino, who could go straight into the squad for Wednesday's match.
|12||J. Obi Mikel|
|Coach: José Mourinho|
for Azpilicueta 63'
for J. Obi Mikel 63'
for Oscar 80'
|Terry: Too long between titles|
|Pepe puts Morata friendship aside for Champions League match-up|
|Hazard can be as good as Messi, Ronaldo - Fabregas|
|Carlisle ´deeply ashamed´ about suicide attempt|
|Tevez planning to win Champions League with Juve|
|Blatter ´knows absolutely nothing´ - Maradona|
|Allegri: Ancelotti a smart man|
|Sunderland academy coach to manage Oldham|
|Primeira Liga Review: Braga secure Europa League berth|
|Bruce backing Hull to respond against Burnley|
|Almeria 2 Celta Vigo 2: Bifouma, Zongo inspire hosts´ comeback|
|Arsenal can mount title bid - Wenger|
|Turkish Super Lig Review: Besiktas and Galatasaray remain locked at the top|
|Cagliari 4 Parma 0: Festa revival back in gear|
|Hull City 1 Arsenal 3: Sanchez at the double as visitors close on second|
|Blackpool - Huddersfield game will not be finished|
|Allegri vindicated by Juventus success|
|Russian Premier League Review: Krasnodar close the gap as Zenit slip up|
|Al Ahly dismiss Garrido|
|MLS Preview: Kinnear returns to Dynamo with Earthquakes|
|Ancelotti all out for victory against Juventus|
|Ramires recovering well after sickness|
|Prince Ali would back rival FIFA candidate to oust Blatter|
|Barcelona v Bayern Munich: Guardiola makes Camp Nou return|
|Kruse a target for Wolfsburg - Allofs|
|Fletcher backing Bournemouth to ´surprise a few´|
|Bremen agree deal with Fritz|
|Carver gets Newcastle backing|
|Blaszczykowski suffers groin tear|
|Boateng warns of Barca ´storm´|
|Brouwers agrees Gladbach extension|
|Benzema to miss Turin trip|
|England great Jimmy Greaves suffers stroke|
|Cabaye concerned by bit-part role at PSG|
|Parry: Anfield expansion a major boost|
|Ki targets Arsenal win and seventh spot|
|Pirlo eyes potential Champions League swansong|
|Mourinho rounds on critics after clinching title|
|Henderson: Liverpool can push on without Gerrard|
|Lack of goals a concern for Van Gaal|
|Hard to keep Benteke - Bacuna|
|MLS Review: Sporting KC end Chicago streak, Martins brace furthers NYC pain|
|Copa Libertadores Preview: River eye revenge in Superclasico|
|Garcia lauds ´impressive´ Roma|
|Pavon goal scores him a BMW for a month|
|Boca beat River in Superclasico|
|Inzaghi to blood youth after third straight Milan defeat|
|Blanc urges PSG to ´remain vigilant´|
|La Liga Review: Valencia go clear of Sevilla, crisis-stricken Elche safe|
|CAF Champions League Review: ES Tunis dumped out by Al Merreikh|
|Masterful Mourinho has Premier League and Chelsea singing his tune|
|Nantes 0 Paris Saint-Germain 2: Cavani nets again as Ibrahimovic returns|
|Napoli 3 Milan 0: Late treble saves hosts|
|Primeira Liga Review: Porto edge past strugglers Vitoria|
|Bundesliga Review: Hamburg claim last-gasp winner, Gladbach close in on Wolfsburg|
|Pochettino: Hart heroics the difference|
|Ligue 1 Review: Monaco remain on course for third, Lille cruise past Lens|
|Pellegrini silent over City future|
|Rome derby not on Lazio´s radar, says Pioli|
|Pardew laments penalty calls in Palace´s loss to champions|
|Serie A Review: Roma move back into second, Di Natale overtakes Baggio|
|Tottenham 0 Manchester City 1: Aguero heaps more misery on Spurs|
|Mourinho appears to take dig at old nemesis Guardiola|
|Mancini frustrated by resilient Chievo|
|Drogba coy over future after title triumph|
|Chelsea title win will not lead to domination - Mourinho|
|Inter 0 Chievo 0: More frustration for Mancini|
|Terry: I´ve proved Benitez wrong|
|BREAKING NEWS: Chelsea secure Premier League title|
|Chelsea 1 Crystal Palace 0: Title heads back to Stamford Bridge|
|League One Review: MK Dons promoted, as Orient, Notts County and Crawley go down|
|Dortmund striker Ramos set to miss Copa America|
|Williamson denies getting sent off on purpose|
|Eintracht Frankfurt´s Kittel suffers injury blow|
|Juventus v Real Madrid: Serie A kings set for Real test|
|United still control top-four destiny - Young|
|Record finish beyond Stoke - Hughes|
|Wellington Phoenix 0 Melbourne City 2: Surprise win sets up semi-final derby|
|Vidal already focused on Real|
|MLS Review: Revs hand Red Bulls first loss|
|AFC Champions League Preview: Wanderers facing elimination|
|Lyon stepped up despite pressure - Fournier|
|Gerrard anticipating emotional Anfield finale|
|´I´ve always wanted to score a free-kick past Neuer´ - Calhanoglu|
|Negredo: Pellegrini lost faith in me|
|Buffon had title doubts after Conte departure|
|Luis Enrique: I was worried during 8-0 win|
|Wilshere will return to his best - Wenger|
|Rodgers unconcerned by banner|
|Mourinho doesn´t want guard of honour|
|Deportivo La Coruna 1 Villarreal 1: Hosts come from behind|
|Juve canter to title success as Allegri wins over doubters|