Hull City risk being sucked into a relegation scrap if they are unable to avoid a fourth straight Premier League loss versus Crystal Palace.
Steve Bruce's side occupy the relative safety of 11th spot but a run of three league defeats on the bounce, in which they have failed to score a single goal, has narrowed the gap between themselves and the bottom three.
Palace, meanwhile, have climbed the table to 16th and a home victory on Tuesday would underline the contrasting recent fortunes of the two sides.
When they met in November, City held a 10-point advantage over Palace, but if the London club can complete a league double over the KC Stadium outfit, they will draw level with them.
And history on the hosts' side, too, with Hull having returned winless from their last 10 trips to Selhurst Park - a record stretching back to 1986.
Barry Bannan's late goal settled matters in this season's meeting at Hull, when the visitors finished with 10 men following Yannick Bolasie's dismissal.
Both clubs were in action on Saturday in the fourth round of the FA Cup, City earning a 2-0 win at Southend United, managed by their former boss Phil Brown, while Palace were beaten 2-1 at holders Wigan Athletic.
That defeat will allow Tony Pulis' men to focus exclusively on the fight for top-flight survival as Palace seek to end their abysmal record of having been relegated from the Premier League on each occasion that they have competed in it.
Pulis masterminded a 1-0 victory over his old employers Stoke City last time out in the league, Jason Puncheon atoning for his penalty miss against Tottenham by netting the decisive goal.
Hull were beaten 1-0 at Norwich City, a defeat compounded by Tom Huddlestone's late red card, meaning he missed the trip to Roots Hall.
The midfielder is likely to start versus Palace, while Robbie Brady, who featured from the bench against Southend, will also come into consideration for his first league start since early December following a groin problem.
James Chester (hamstring), Joe Dudgeon (knee) and Sone Aluko (calf) are all ruled out.
Much has been made of Palace's sizeable squad - described by one study as "the biggest in Europe" - and Pulis has relatively few injury concerns.
Kagisho Dikgacoi and Jerome Thomas (both calf) could return, while Cameron Jerome, who was ineligible to face his parent club Stoke in the previous league game, is set to start in attack.
Defender Jack Hunt (ankle) and long-term absentee Glenn Murray (knee) remain on the sidelines.
|Coach: T. Pulis|
for Y. Bolasie 64'
for D. Gabbidon 81'
for M. Chamakh 86'
|Juventus 2 Tottenham 1: Benatia bags win for Serie A champions|
|Dembele: I am not the Bundesliga´s next superstar|
|Lyon claim €35m Arsenal offer for Lacazette rejected|
|Donnarumma dreaming of Milan captaincy as he eyes long-term stay|
|Robson: Ibrahimovic can match Van Persie´s first year at United|
|Rooney should remain England captain - Eriksson|
|Emery wants new striker at PSG|
|Santos accept Juventus bid for Gabriel|
|Eriksson expects Sweden to try and tempt Ibrahimovic out of retirement|
|Spurs signing Janssen almost quit|
|Leicester stay best for Mahrez - Ranieri|
|Allardyce to take Mourinho cue on Rooney|
|Ings ready to outdo big-money signings|
|Henderson optimistic over Liverpool campaign|
|Allardyce hardened to the challenge of England post|
|Barcelona announce record revenues for 2015-16|
|Moyes enjoys Sunderland win as Palace beat Colchester|
|Stoke complete Allen signing|
|Roma coach Spalletti warns suitors off Manolas|
|Cresswell out for up to four months with knee injury|
|Burnley fan banned by club for racist abuse|
|Dad won´t let me play at the Olympics - Larsson Sr pulls rank|
|Kostic joins Hamburg on five-year deal|
|Tevez: I´d turn down Chelsea and Napoli to stay at Boca|
|Mayoral inspired by Benzema for Wolfsburg stint|
|Allardyce straight into competitive action with England|
|Liverpool, Sevilla fined for Europa League final incidents|
|Barcelona seal Guillemenot signing as part of new Servette deal|
|Niersbach handed one-year ban over World Cup corruption|
|Chelsea and Everton ´still interested´ as Koulibaly eyes Napoli exit|
|´Still working hard´ - Balotelli trains with Liverpool kids|
|Winter breaks, long-ball football and the World Cup: Allardyce in his own words|
|Inter warn Napoli Icardi is not for sale|
|Zanetti wants Simeone back at Inter|
|Stoke snap up Sobhi|
|PSG tougher under Emery - Lucas Moura|
|Totti not ready for retirement - Pallotta|
|Confident Allardyce reveals plan for England success|
|Pochettino to discard three Tottenham players|
|Allardyce: Rooney must wait for captaincy decision|
|Aubameyang: I will only leave Dortmund for Real Madrid|
|Allegri silences questions on Pogba|
|Bruce stands by decision to quit Hull City|
|Pochettino: Not the right time for Argentina job|
|Inter yet to approach De Boer with Mancini exit rumoured|
|Ancelotti trusts me more than Guardiola - Ribery|
|Wijnaldum rejected Everton for Klopp|
|Pre-season Manchester derby cancelled|
|Coutinho excited by ´fast´ Liverpool recruits|
|Cristiano Ronaldo and Conor McGregor step into the ring together|
|Mancini coy on reports linking Icardi to Napoli|
|Nolito reveals why he chose Man City over Barcelona|
|Inter 1 Paris Saint-Germain 3: Icardi absence in defeat fuels Napoli talk|
|MLS Review: Wright-Phillips double inspires Red Bulls to New York derby rout|
|James seeks more game time at Madrid|
|Rooney: I want to be a manager|
|Mignolet welcomes Karius challenge in Liverpool number one battle|
|Batshuayi buoyed by winning vibes at Chelsea|
|Moyes and Sunderland players diverted after plane fault|
|´Loved´ Varane targets long Madrid stay|
|Kostic set for Hamburg medical|
|Leicester crying over Kante sale - Ranieri|
|Schurrle the perfect Mkhitaryan replacement - Tuchel|
|West Ham face anxious wait on Cresswell injury|
|Mourinho will accept criticism from United legends|
|Bertolacci desperate for fresh start after underwhelming first season at Milan|
|Hoops hand Toure one-year deal|
|Origi ready to fight for Liverpool spot|
|Emery wants PSG stay for ´fantastic´ Matuidi|
|No Barcelona offer for Vietto - Cerezo|
|Burnley apologise for racist abuse from supporter|
|Guardiola will not rush Kompany comeback|
|Of course I´ll shake Guardiola´s hand, snaps riled Mourinho|
|Watzke: No more signings for Dortmund|
|Roma expect Manolas to snub Premier League move|
|Adriano set to leave Barcelona for Besiktas|
|Manchester United in worst possible situation - Mourinho|
|Sporting would have to sell stadium to afford Van Persie - Jesus|
|Jonas´ agent confirms Barcelona approach|
|No problem with Mourinho, insists Guardiola ahead of derby in China|
|Toronto´s hat-trick hero Giovinco: I´m back|
|Drogba revels in ´special night´, dedicates hat-trick to family|
|MLS Review: Hat-tricks for Drogba and Giovinco as stars shine|
|Whelan backs Liverpool for top-four finish|
|Pellegrini still waiting for right offer|
|Ronaldo deserves to win Ballon d´Or - Vazquez|
|Phelan wants Hull job|
|Alaba saddened by Gotze exit|
|Morgan: Vardy right to re-sign|
|Maradona ´hurting´ as Higuain closes on Juventus move|