Fernando Llorente's looping header rescued a 1-1 draw for 10-man Juventus against Lazio at the Stadio Olimpico on Saturday.
The Serie A leaders - who had lost in the same stadium to Roma in the Coppa Italia on Tuesday - appeared to be heading for their first league defeat since October when Antonio Candreva notched from the penalty spot following the dismissal of Gianluigi Buffon, who brought down Miroslav Klose in the area.
But Llorente levelled proceedings in the second half to leave Lazio waiting for a first league triumph over Juventus since December 2003.
In a tight first half, Juve controlled possession but were hindered when keeper and captain Buffon was beaten to an intricate throughball by Klose, with Candreva keeping his cool to open the scoring from 12 yards.
The second half continued in a similar fashion, and the champions deservedly equalised when a well-0worked move was finished by Llorente's fine header.
The draw ends Juve's 12-match winning league run, while Lazio have now won two and drawn two league matches since Edy Reja returned as coach earlier in January.
Lazio restored Hernanes to the starting XI after he scored a last-minute winner at Udinese last weekend, while Angelo Ogbonna moved to centre-back for the visitors with Giorgio Chiellini suspended.
The visitors started well but only had a speculative half-volley from Arturo Vidal after nine minutes to show for their early efforts.
At the other end, Lazio almost took the lead in bizarre circumstances when Klose caught Buffon in possession and the Germany international's challenge forced the ball just wide of goal.
Buffon's night went from bad to worse when he was shown a straight red card for denying a clear goalscoring opportunity after bringing down Klose in the area after 24 minutes.
From the resulting penalty, Candreva sent replacement goalkeeper Marco Storari the wrong way to break the deadlock.
Despite that setback, Juve continued to see plenty of the ball and they created a great opportunity nine minutes before half-time when Stephan Lichtsteiner's low centre was collected by Llorente, who turned sharply in the box and forced a smart save from Etrit Berisha.
Juve showed no signs of suffering with their numerical disadvantage after the break, continuing to probe but struggling to orchestrate clear-cut chances.
Antonio Conte's charges showed their ruthlessness on the hour mark, however, as Llorente met Lichsteiner's pin-point cross with a looping header to the far corner.
Buoyed by the leveller, Juve duly pushed for a winner and Carlos Tevez forced Berisha into a superb near-post save with a fierce strike.
However, with 15 minutes remaining, Storari produced a fine point-blank save to deny Klose's header from Cristian Ledesma's whipped free-kick.
A near carbon copy of that set-piece then led to Storari holding well from Klose's header, and the hosts kept up their late pressure when substitute Balde Keita curled an effort against the post in the 85th minute, but both sides were forced to settle for a point.
|Everton 1 Lyon 2: Koeman feeling the heat, while Williams brawl overshadows spectacle|
|AC Milan 0 AEK Athens 0: Frustration mounts for Montella in dour draw|
|Giroud promised special winner, Wenger reveals|
|Former Croatia striker Klasnic undergoes third kidney operation|
|Red Star Belgrade 0 Arsenal 1: Giroud´s special winner lights up drab encounter|
|Shakespeare: Leicester will ´pull away´ from Premier League danger|
|Robben yet to hold talks over new Bayern Munich contract|
|Bilic denies West Ham have discipline problem|
|Benteke progressing ´ahead of schedule´|
|Ancelotti to Leicester unlikely, says Clement|
|Dyche not aware of any approach amid Leicester speculation|
|I love you, take my watch! – How Arnautovic earned a special gift from Mourinho|
|´Surprised´ Appleton calls for Foxes focus after Shakespeare sacking|
|Brighton boss Hughton feels ´unacceptable´ behaviour remains in football|
|Benzema ´very happy´ at Real Madrid amid Arsenal rumours|
|Azpilicueta admits to low mood in Chelsea camp|
|Bacca: I played for the worst AC Milan in history|
|Aluko ´100 per cent´ in England contention, says interim boss|
|Injured Napoli striker Milik hints at loan move|
|Dortmund not expecting Reus exit|
|Neymar plans to emulate Messi by mentoring Mbappe|
|Mourinho still unclear on fitness of Pogba and Fellaini|
|Heynckes happy with Muller form|
|Kane describes Ronaldo as ´role model´ following shirt swap|
|PSG star Mbappe: Monaco need time|
|I have full support of Everton board, claims Koeman|
|Wilshere: Arsenal´s character can´t be questioned|
|No-one can compete with Messi – Bartomeu|
|Man United risk losing identity under Mourinho – Bellamy|
|Valverde hopes Messi scores 200th European goal this season|
|Stop worrying about Chelsea – Conte hits back at Mourinho|
|Roma better than Chelsea, says Nainggolan|
|Basel coach Wicky demands more focus|
|Heynckes calls for patience from Bayern´s reserve stars|
|Emery calls for PSG improvement despite perfect start|
|Pique handball instinctive, says Barcelona boss Valverde|
|Dzeko was born to score – Di Francesco|
|Lemonis rues Olympiacos collapse against 10-man Barca|
|Rodgers: Individual class inhibiting Celtic|
|David Luiz experiment failed, admits Conte|
|Allegri not impressed despite crucial win|
|Svilar risks a lot – Mourinho was aware of Benfica youngster´s shortcomings|
|We played better against Atletico – Hazard|
|Job done for Mbappe and PSG after another big win|
|Simeone maintains ´absolute´ belief in Atletico despite Qarabag draw|
|CSKA Moscow 0 Basel 2: Xhaka, Oberlin do the damage|
|Juventus 2 Sporting CP 1: Late Mandzukic intervention saves wasteful Bianconeri|
|Bayern Munich 3 Celtic 0: Hoops outclassed on Heynckes´ return to Europe|
|Chelsea 3 Roma 3: Hazard brace rescues Conte´s men after Dzeko double|
|Anderlecht 0 Paris Saint-Germain 4: Mbappe takes one record as Cavani closes on another|
|Barcelona 3 Olympiacos 1:Ton-up for Messi as Pique sees red|
|Benfica 0 Manchester United 1: Rashford goal settles poor game after woeful Svilar error|
|Messi joins Ronaldo in European 100-goal club|
|Good results are on the way in the league - Salah|
|Algeria restore Madjer to the helm|
|Griezmann eyes qualification despite Atleti´s Qarabag stumble|
|FA chief Glenn denies Aluko´s ´bordering on blackmail´ claim|
|Mbappe surpasses Kluivert as Champions League´s highest-scoring teenager|
|Ozil is a warrior - Pires sympathises with Arsenal star|
|Benfica teen Svilar breaks Casillas´ Champions League record against Man Utd|
|Balotelli can improve even more - Favre|
|It was special to face role model Modric, says Winks|
|Robben named for Champions League century|
|You can´t question Arsenal´s character - Wenger hits back at Deeney|
|Qarabag 0 Atletico Madrid 0: Simeone´s side in trouble after shock draw|
|Guardiola´s Catalonia stance dismissed by Spanish minister|
|Oldham appoint Wellens over Scholes, Seedorf|
|FA apologises over Sampson remarks to Aluko and Spence|
|Montella willing to accept ´exaggerated´ Milan criticism|
|Napoli confirm Insigne adductor strain|
|Urawa Reds 1 Shanghai SIPG 0 (2-1 agg): Rafael Silva books Al Hilal decider|
|Not a tragedy if Italy miss World Cup, says Zola|
|Hummels: Bayern players contributed to Ancelotti´s sacking|
|Dzeko considers Chelsea among Champions League contenders|
|Cavani doesn´t need to be friends with Neymar|
|Ozil and Sanchez committed to Arsenal, Mertesacker claims|
|Don´t stress it - De Bruyne relaxed over initial Man City contract talks|
|Nagelsmann´s path will lead to Bayern, says Heynckes|
|Stones satisfied with strong Manchester City showing|
|Redknapp: Spurs boss Pochettino could manage Real Madrid|
|That will be hard to beat – Klopp revels in record win|
|Spurs showed they can compete with elite - Pochettino proud after Madrid draw|
|Ballon d´Or? We all know Messi is best, says Valverde|
|He´s getting better – Zidane backs Benzema|
|Napoli star Insigne unsure if he´ll be fit to face Inter|
|Manchester City can win Champions League, says Napoli boss Sarri|
|Berizzo plotting Sevilla´s revenge after Spartak Moscow humiliation|
|Porto boss Conceicao defends Casillas omission|
|We know it´s difficult now, admits Dortmund boss Bosz|
|It´s tough but it´s not over - Van Bronckhorst|
|Monaco know it will be difficult to qualify now, says Sidibe|
|I don´t know what happened - Sarri bemused by Napoli´s slow start|
|We are growing consistently, insists upbeat Zidane|