Guly do Prado grabbed his first goal in just over two years as Southampton beat Yeovil Town 2-0 to reach round five of the FA Cup.
The Brazilian converted a penalty midway through the opening half at St Mary's, after referee Phil Dowd had spotted a handball from Shane Duffy, to score for the first time since January 14 2012.
Jay Rodriguez and Adam Lallana hit the crossbar for the Premier League side either side of Guly's strike.
However, Championship strugglers Yeovil had chances of their own prior to teenage substitute Sam Gallagher wrapping things up for Southampton with his first senior goal 20 minutes from the end.
Having beaten second-tier opposition at home in the third and fourth rounds, Southampton will hope for another favourable draw when the last-16 ties are revealed on Sunday.
Yeovil can take heart from a spirited display, which belied the fact the club have won only five league games this season.
Rickie Lambert (hamstring) and Artur Boruc (back) missed out with minor injuries as Southampton, minus the suspended Pablo Daniel Osvaldo, fielded a starting XI showing six changes from last weekend's draw at Sunderland.
Striker Ishmael Miller was back in Yeovil's team, having returned to the club from Nottingham Forest this week for a second loan spell, while Jamie McAllister replaced the injured Zoumana Bakayogo.
The visitors started brightly, with Joe Ralls and James Hayter each bringing early saves from Southampton goalkeeper Kelvin Davis.
However, Rodriguez soon forced Marek Stech into action at the other end before heading against the crossbar from Nathaniel Clyne's cross in the 18th minute.
And Southampton moved ahead shortly after, Guly sending Stech the wrong way from 12 yards after Duffy had been penalised for handling in the area.
A mis-directed cross from Lallana then clipped the top of the bar prior to Hayter spurning Yeovil's best chance of the half in the 37th minute.
The experienced striker met Ralls' left-wing cross but was denied by Davis from point-blank range.
Southampton forward Rodriguez saw a first-time effort saved three minutes later, while Miller blazed over on the stroke of half-time.
Yeovil threatened again immediately after the interval, with Davis reacting well to tip Luke Ayling's effort past the post.
Davis made a more comfortable stop from John Lundstram before Southampton's James Ward-Prowse cleared the bar with a powerful long-range volley.
With the game becoming increasingly open, Stech kept out shots from Clyne and 18-year-old Gallagher.
The latter then put the match beyond Yeovil with a fine goal, which saw him jink past two players before applying a low finish.
Gallagher had another effort blocked on the goalline and Stech made a superb late save from Steven Davis, but it mattered little as Southampton eased to victory.
|Coach: M. Pochettino|
for Guly 56'
for A. Lallana 73'
for J. Ward-Prowse 84'
|Lampard targets MLS play-offs for City|
|MLS Review: Goals galore as DC United win 10-goal thriller|
|Ronaldinho returns and helps Fluminense to win|
|Keane: United won´t overtake Chelsea|
|Casillas has the ´enthusiasm of a 20-year-old´ - Lopetegui|
|Blanc hopeful over Ibrahimovic knee injury|
|Guardiola laments late goal in Supercup defeat|
|Tuchel plans to keep Bender|
|Hecking happy with Wolfsburg discipline after Supercup win|
|Arsenal players too interested in selfies and six-packs - Keane|
|Confusion over Ibrahimovic´s PSG future|
|Sporting Lisbon 2 Roma 0: Slimani, Mane inspire Portuguese hosts|
|Rodgers feeling ready for new campaign|
|Khedira to miss Supercoppa|
|Paris Saint-Germain 2 Lyon 0: Aurier and Cavani seal more silverware|
|Wolfsburg 1 Bayern Munich 1 (5-4 on penalties): Super-sub Bendtner nicks it for Pokal champions|
|Lampard´s long-awaited New York City debut ends in defeat|
|Casillas the spot-kick hero for Porto|
|Monk bullish ahead of season opener at champions|
|Marseille 2-0 Juventus: Night to forget for Serie A champions|
|Swansea end pre-season with yet another draw|
|HJK 0 Liverpool 2: Origi and Coutinho on target|
|Juventus rocked by Khedira injury scare|
|Lens and Pantilimon star as Sunderland beat Hannover|
|Pardew hopeful of concluding Wickham deal|
|Martinez allays Lukaku fears|
|Stuttgart 4 Manchester City 2: Cause for concern for Pellegrini|
|Wasteful Bournemouth held by Hoffenheim|
|Jerome seals Norwich win|
|Souare´s first goal ensures Palace draw|
|Sinclair hits hat-trick in Villa draw|
|Leicester end pre-season with thrilling Birmingham win|
|Wood and Mowatt condemn Everton to friendly defeat|
|Coloccini not involved as Newcastle lose to Gladbach|
|Borussia Dortmund 2 Real Betis 0: Ramos scores on return from injury|
|Stoke lose to Cologne on Afellay debut|
|Norwich capture goalkeeper Kean|
|Jovetic hits out at Pellegrini following City exit|
|Jones backing new boys to spark United revival|
|Scottish Premiership Review: Celtic up and running, Dundee hammer Kilmarnock|
|Can keen to learn from Milner|
|Immobile on the mend following friendly scare|
|Sagan Tosu 1 Atletico Madrid 1 (1-4 on penalties): Simeone´s men need spot-kicks|
|Cahill: Big-spending rivals will make title race tougher|
|Roberto happy to play full-back for Barca|
|Gestede eager to make his mark at Villa|
|I want to play more and score more - Remy|
|Lambert influence important, says Pulis|
|Benteke a ´bargain´ buy - Rodgers|
|Zola: Qatar would be ideal for Balotelli, Cassano|
|Suarez: I´m not among world´s best|
|PSG ready despite ´chaotic´ pre-season - Blanc|
|Arsenal thumping still hurts - Fournier|
|Aubameyang targets Champions League success|
|Rooney set for Everton return|
|Cech can match Van der Sar - Wenger|
|Mourinho ponders Wenger´s losing record against him|
|CBF confirm Fred failed a doping test|
|Bournemouth beaten by battling Cardiff|
|Immobile injury overshadows Sevilla win at Vicarage Road|
|Lambert at the double on West Brom bow|
|Real sign up Spain starlet Vallejo|
|Valencia blow for West Ham|
|Elche cleared to play in Segunda Division|
|Baker pens a new Villa deal|
|Lambert makes Albion switch|
|Gillingham and Scally found guilty of ´race victimisation´|
|Inter complete Jovetic signing|
|Arsenal v Chelsea: Mourinho cools Wenger rivalry ahead of Wembley meeting|
|Villa snap up Gestede|
|Villa land Veretout|
|Mourinho coy on fresh Stones bid|
|Aubameyang commits to Dortmund|
|Torres on the hunt for trophies with Atletico|
|Cazorla and Walcott sign new Arsenal deals|
|Quick start vital in Arsenal title bid - Wilshere|
|I have received no offers - Guardiola|
|Barcelona to monitor Turan injury|
|Zorc ´surprised´ by Grosskreutz-Tuchel row|
|Phil Neville could be England manager - Moyes|
|UEFA to investigate Shakhtar´s Fred selection|
|City loan Unal to Genk|
|China v South Korea: Stielike looking for new options|
|North Korea v Japan: Halilhodzic to unearth new faces|
|Drogba: I want to be ready, not a burden|
|Hamstrung Clasie in doubt for Southampton league opener|
|West Ham goalscorer Zarate bemoans Astra comeback|
|Negredo quashes Valencia exit rumours|
|´This is not my Sampdoria´ - president Ferrero|
|Criscito could join Inter - agent|
|CBF endorse Zico´s FIFA presidency campaign|
|Hawit to handle CONCACAF´s referee review|
|Falcao is a ´top, top player´ - Terry|
|Tuchel pleased by Dortmund fighting qualities|
|Premier League rules out schedule changes for Champions League clubs|
|UEFA Europa League Review: Southampton stroll as Sampdoria are humiliated|