Gabriel Humberto Calderon's first game as Real Betis head coach ended in a disappointing 4-2 defeat at Celta Vigo on Friday.
Beleaguered Betis - who have only won twice in La Liga this season - took the lead through Ruben Castro on 17 minutes, but were unable to build on that advantage and slumped to a 3-1 half-time deficit at Estadio de Balaidos, with a Fabian Orellana brace sandwiching Charles' effort.
The situation worsened when Nolito put Luis Enrique's charges 4-1 ahead with 17 minutes remaining.
Although Castro notched a consolation, bottom club Betis slumped to a fourth straight defeat and have now gone 14 league matches without a win.
After withstanding sustained Celta pressure, Betis moved into a surprise lead when the unmarked Castro scooped Juanfran's superb cross past goalkeeper Yoel.
But the scores were levelled on 22 minutes when a terrific ball from Rafinha was headed home by Orellana.
The home fans were able to celebrate on two further occasions before the break, as Charles ghosted in at the near post to head home before showing great generosity to lay on Orellana's second.
There was no let up from the home side after the break and Celta deservedly grabbed a fourth when Nolito tapped in from close range.
Betis reduced the arrears in the 78th minute, Castro capitalising on uncertainty in the Celta box to fire home, but it was too little, too late for the visitors.
Calderon's evening worsened in injury time when Cedric Mabwati was shown a straight red card for a dangerous sliding tackle on Rafinha.
The win eases the relegation fears of Celta, who move up to 13th position, six points clear of the drop zone.
|Kenya 0 Ethiopia 0 (agg 0-2): Hosts sent out of CHAN qualifiers after second penalty miss|
|Dortmund put 17 past Olympians, Bremen hand out thrashing|
|Dinamo Zagreb confirm arrests of coach and club president|
|I didn´t know who Wimbledon guest Klopp was - Brown|
|LeBron James backs Liverpool captain Henderson for FIFA 16 cover.|
|Ramos: I am not negotiating with anyone|
|Valencia complete Mina swoop|
|United States v Japan: US seek final redemption|
|Hanousek consigns Celtic to defeat|
|Roma confirm Dzeko interest|
|Arsenal forward Podolski completes Galatasaray switch|
|Warm Dortmund welcome delights Tuchel|
|Silva vows to fight for Madrid place|
|Mancini hints at Shaqiri and Santon departures|
|Bojan raring to go after return from injury|
|Babel backs Firmino to shine at Liverpool|
|Falcao must wait to impress, warns Chelsea favourite|
|Bartomeu: Deal in place for Turan|
|Parejo re-signs with Valencia|
|MLS Review: Sounders return to winning ways|
|Klinsmann unhappy with USA performance|
|High hopes for Paraguay - Diaz|
|Gareca: More to come from Peru|
|Gerrard had European offers|
|Argentina out to spoil Chile´s party - Martino|
|Sampaoli: Chile won´t change style|
|Di Maria will come good at United - Rojo|
|Peru 2 Paraguay 0: Gareca´s men finish third at Copa|
|United States 4 Guatemala 0: Klinsmann´s men win comfortably|
|´I’d prefer no-one to know my name´ - Bassett|
|Matthews completes Sunderland move|
|Podolski set for Galatasaray medical|
|Gundogan inspires Dortmund victory|
|Inter confirm Montoya capture|
|Murillo joins Inter, as Kuzmanovic and Obi depart|
|Falcao signing not a risk, says former Chelsea star|
|Deeney agrees new Watford deal|
|Confidence and service the key to Falcao success at Chelsea|
|No bids for ´Chelsea target´ Baba, claim Augsburg|
|Derby swoop for Ince|
|Fiorentina consider legal action over Salah ´no-show´|
|Chelsea the team to beat in the Premier League, says Neville|
|Storari exits Juve for Cagliari|
|UEFA removes FFP restrictions on Man City and PSG|
|West Brom hope for new owners within the month|
|Chelsea agree loan deal for Falcao|
|Kuyt eyes trophies on Feyenoord return|
|Chile v Argentina: History beckons ahead of Copa America final|
|Wallace extends Monaco loan|
|Mihajlovic wants to instill fear factor at Milan|
|Mignolet improving at Liverpool - Grobbelaar|
|Mumbai City name Anelka player-manager|
|Olivia the parrot predicts Japan to win Women´s World Cup|
|Lusitans coach blasts Bilic´s ´lack of respect´|
|Sakho eyes more Europa League wins|
|Gareca wants Peru to keep building|
|Chile ´no chance´ if Argentina produce their best - Diaz|
|Ocampos joins Marseille permanently|
|Europa League Review: Cloud-nine Brondby ignite opening round|