Clarence Seedorf returns to San Siro as Milan coach on Sunday, while Juventus will look to extend their record winning streak in Serie A.
Former Netherlands international Seedorf retired from playing on Tuesday in order to replace Massimiliano Allegri, who was sacked following last weekend's 4-3 defeat at struggling Sassuolo.
The 38-year-old represented Milan with great distinction in his playing career, scoring 62 goals in 432 appearances and winning two Serie A titles, two UEFA Champions Leagues and one Coppa Italia crown in a 10-year stay.
Mauro Tassotti took charge of Wednesday's 3-1 Coppa Italia win over Serie B side Spezia, and Seedorf's reign as coach begins with a tricky visit of Verona to Lombardy.
Verona have adapted superbly to life back in the top flight following last season's promotion from Serie B and sit sixth after 19 games, having racked up 10 wins.
Luca Toni's nine goals in 17 games have been key to that, although they fell to a 3-0 home defeat to Napoli last time out.
They may look to Milan's woeful home form as an opportunity to respond strongly, however.
Milan's win against Atalanta on January 6 was their first on home soil in seven games in all competitions, but they followed that up with the stunning loss to Sassuolo - whose four goals were all scored by teenage striker Domenico Berardi.
Champions Juventus, meanwhile, will be confident of extending their record winning run in Serie A to 12 games when they host Sampdoria on Saturday.
Antonio Conte's side have won all nine of their home games in the league this season, but Samp are the last side to have beaten Juve on their own patch, having picked up a 2-1 win at Juventus Stadium on January 6 last year.
Juve's closest title rivals Roma and Napoli will face Livorno and Bologna respectively hoping for a rare slip up from the champions, with Fiorentina and Inter hoping Rafael Benitez and Rudi Garcia's sides lose as they look to boost their UEFA Champions League hopes at Catania and Genoa.
Sassuolo, with morale boosted after their win over Milan and the clubs below them facing tough games, host Torino with the bottom five's final side Chievo hosting Parma.
Elsewhere, Lazio travel to Udinese yet to be beaten under returning coach Edy Reja, and Atalanta host Cagliari.
|2||M. De Sciglio|
|34||N. de Jong|
|Coach: C. Seedorf|
for D. Bonera 52'
for K. Honda 63'
for Robinho 78'
|Del Bosque frustrated by friendly defeat|
|Bradford City 0 Chesterfield 1: Harrison strike moves visitors into play-off places|
|Portugal 0 Cape Verde 2: Hosts suffer shock friendly defeat|
|Townsend takes swipe at TV pundit Merson|
|Plane issue grounds England squad|
|Israel 0 Belgium 1: Fellaini nets again as Kompany sees red|
|N´Koulou returns to full Marseille training|
|Netherlands 2 Spain 0: Hosts ease pressure on Hiddink|
|Italy 1 England 1: Townsend leveller rescues draw|
|Ghana 1 Mali 1: Sako spot-kick denies Black Stars|
|Luxembourg 1 Turkey 2: Calhanoglu stakes claim with late winner|
|Ghana 1-1 Mali: Sako spot-kick denies Black Stars|
|Italy 1-1 England: Townsend rocket earns draw for Three Lions|
|Rummenigge marvels at ´genius´ Guardiola|
|Switzerland 1 United States 1: Stocker seals draw after Altidore red|
|Young players should not need a break, says Dyche|
|Tottenham acquire final piece of land for new stadium|
|Portugal 0-2 Cape Verde Islands: African minnows claim historic victory|
|Netherlands 2-0 Spain: Rejuvenated Dutch ease pressure on Hiddink|
|Switzerland 1-1 USA: Altidore sent off in friendly draw|
|Palestinian FA speaks out against Israel-Belgium venue selection|
|Valdes enjoying football again after injury nightmare|
|Emotional Cha retires ´a happy man´|
|Dortmund´s Kirch suffers knee injury|
|Newcastle need to be mentally prepared, says Williamson|
|Leno ´knows nothing´ of Real interest|
|Tunisia to compete in AFCON after apology|
|Van der Vaart not allowing future to affect his game|
|Vlaar: Sherwood has reduced stress levels|
|Roma hit by Gervinho hamstring blow|
|Jones optimistic over Everton´s strike partnership|
|Milik sustains knee ligament damage|
|Georgia fear stadium closure for Scotland clash|
|Zamparini: Juventus and Arsenal have bid for Dybala|
|South Korea 1 New Zealand 0: Lee nets late winner|
|Japan 5 Uzbekistan 1: Five-star hosts maintain Halilhodzic start|
|European clubs benefit from UEFA agreement|
|Vassell: Sky is the limit for Kane|
|Manchester United move would be an ´honour´ for Coentrao|
|Insigne out to bolster Napoli season after lay-off|
|Rooney warns Kane over ´clever´ Italy defenders|
|Rangers results reveal £500,000 Newcastle clause|
|Southampton announce £33.4m profit|
|´I am a very flexible man´ - Van Gaal|
|A-League Preview: Top spot up for grabs|
|Portugal - Cape Verde Preview: Andre and Oliveira eager for international bows|
|Puerto Rico 0 Canada 3: Floro´s men rout hosts|
|Xavi denies Al Sadd link|
|Fernando´s life ban upheld by CAS|
|Argentina - Ecuador Preview: Messi remains doubtful for friendly|
|Falcao equals Colombia´s all-time scoring record|
|Macedonia trip good learning curve - Postecoglou|
|Macedonia 0 Australia 0: Stalemate in Skopje|
|Del Bosque not out for Netherlands revenge|
|Burton Albion 1 Stevenage 1: Both teams score at wrong end in draw|
|Pekerman: I have no say on Falcao´s Manchester United future|
|Buffon has studied England new boy Kane|
|Conte urges patience from Italy fans|
|Johnson tasked with keeping Cheltenham up|
|Rooney not keen on Serie A switch|
|Kane to make first England start|
|Colombia 3 Kuwait 1: Spot-on Falcao equals Iguaran record|
|Goal-shy Barkley eyes striker´s role|
|UEFA opens disciplinary proceedings against Montenegro and Russia|
|Draxler and Choupo-Moting back in training|
|Ghana v Mali: Last chance to impress before Giresse return|
|Wilson: Gibraltar getting stronger|
|Mata confident of Spain future|
|Armenia coach Challandes resigns|
|Hiddink rubbishes talk of Dutch negativity|
|Portugal v Cape Verde: Santos set to rotate|
|Loren hails Moyes for Sociedad surge|
|Cruyff brands Netherlands ´a disgrace´|
|Kick It Out backs Barnes over race comments|
|Argentina v Ecuador: Messi remains doubtful for friendly|
|Coates backs Hughes ambition at Stoke|
|Atletico able to call on Saul again|
|Italy v England Preview: Kane set to start after dream debut|
|Zidane would accept Real job|
|Hernandez frustrated by lack of Real opportunities|
|Spartak donate money to 102-year-old fan after robbery|
|Clasie pulls out of Netherlands squad|
|Italy´s Bertolacci out of England friendly|
|Newcastle post record profit as Ashley debt stays the same|
|Al Sadd: We want Xavi to bring tiki-taka|
|Lacazette expected frosty Saint-Etienne reception|
|Barnes: I can´t get back into management because I´m black|
|Rooney praises England aggression|
|Southgate tips Kane for return to U21s|
|Mexico v Paraguay: Goals in order for Copa America aspirants|
|Netherlands - Spain Preview: Wijnaldum rallies behind under-fire Hiddink|
|Peru v Venezuela: Sanvicente wants Venezuelan response|
|Carvalho confident of playing Juventus|
|Neymar demands protection after Medel stamp|
|MLS Review: RSL, Fire secure breakthrough wins|
|Firmino firmly on radar - Dunga|