Manchester City have a remarkable milestone in sight as Manuel Pellegrini's men eye their 100th goal of the season when Cardiff City visit.
The 5-0 hammering of Blackburn Rovers in Wednesday's FA Cup third-round replay took the 2011-12 Premier League champions to 99 goals in all competitions.
Cardiff face a huge task to stem the flow of goals at the Etihad, where the hosts have netted 38 times in 10 league matches, all of which have ended in victory for Pellegrini's charges.
And the visitors' return of six points from 10 away matches will bring them little cause for optimism on Saturday.
However, the Welsh outfit do not have to think back too far to find inspiration ahead of what promises to be arguably their toughest top-flight challenge since earning promotion last season, having beaten this weekend's opponents 3-2 on home soil in August.
That was Cardiff's first Premier League victory, but only three have followed since, with manager Malky Mackay paying the price and Ole Gunnar Solskjaer now in his place.
While the Norwegian's tenure begun with a promising 2-1 FA Cup triumph over Newcastle United, his first league match saw a 2-0 loss to an out-of-form West Ham team last Saturday who climbed above Cardiff and left Solskjaer's side in the bottom three.
Manchester City are competing at the opposite end of the table and still harbour hopes of completing an unprecedented quadruple, with Premier League, UEFA Champions League, FA Cup and League Cup honours up for grabs.
The title race is likely to be Pellegrini's top priority and the Chilean has guided his side to six consecutive league triumphs as part of a 10-match unbeaten run in the Premier League.
Pellegrini was further boosted by the return of striker Sergio Aguero against Blackburn, with the Argentine scoring within 50 seconds of his introduction from the bench after recovering from a calf injury.
Squad depth is one of Manchester City's key strengths but they are not without their injury problems.
Midfielder Samir Nasri, an ever-present in the league, suffered a knee injury in the 2-0 victory over Newcastle last Sunday will be out for six to eight weeks, while Jack Rodwell and Stevan Jovetic (both hamstring) are also ruled out.
Yaya Toure was rested in midweek as he continues to nurse a back problem, but is set to return to the squad, while David Silva will also be in contention after being left out against Blackburn having picked up an unspecified knock.
Solskjaer has very few injury or suspension concerns, but Cardiff's form will have been occupying his thoughts.
A run of one win from 11 Premier League fixtures has dragged Cardiff into a relegation dogfight and they have failed to score in three of their last four league outings.
Jordon Mutch, the club's joint top scorer on four league goals, has missed the last two games with a hamstring problem, but could come back into the reckoning.
|Coach: M. Pellegrini|
for Negredo 62'
for David Silva 80'
for Jesús Navas 82'
|Van Gaal blames United errors for draw|
|Real Sociedad 1 Getafe 2: Yoda brace stuns San Sebastian|
|West Brom 2 Manchester United 2: Blind rescues point for Van Gaal´s men|
|Russian Premier League Review: CSKA, Rubin claim easy victories|
|De Boer calls for confident Ajax|
|Robben hails Roma ahead of Champions League showdown|
|Turkish Super Lig Review: Besiktas win again, Sneijder settles derby|
|Monaco v Benfica: Jardim to face off with former rivals|
|Cordoba turn to Djukic|
|Anderlecht v Arsenal: Wenger on the defensive after domestic struggles|
|Ferrer fired by Cordoba|
|Olympiacos v Juventus: Allegri´s men face stern Greek test|
|PSG will not hide behind injuries, says Blanc|
|Podolski rubbishes Spurs rumours|
|Galatasaray among teams fined by UEFA|
|Stoke loan out Butland and Wilkinson|
|Atletico Madrid v Malmo: Turan warns Spanish champions|
|Di Matteo: Sporting clashes crucial|
|Donbass Arena heavily damaged by shelling|
|Toure getting back to his best - Pellegrini|
|Liverpool v Real Madrid: Rodgers marvels at Real quality|
|Starke injury adds to Bayern´s goalkeeper troubles|
|Bayer Leverkusen v Zenit: Bellarabi wants consistent focus|
|Birmingham part company with Clark|
|Roma not afraid of Bayern, insists Garcia|
|Ludogorets v Basel: Sousa after more of the same|
|Galatasaray v Borussia Dortmund: Reus calls for unity|
|Luis Enrique coy on Messi sub snub|
|Indian Super League Preview: Chennaiyin with chance to go top|
|Costa to miss Maribor clash|
|League Two Preview: Wilcox promises York improvement, Tranmere seek to end losing streak|
|League One Preview: Grayson excited by Preston form|
|Championship Preview: Birmingham begin life without Clark, Fulham out to continue revival|
|Ronaldo will retire at Real insists Ancelotti|
|Musa: City are weak at the back|
|El Shaarawy: I could have played better|
|Allardyce targets City scalp|
|Bale suffers hip injury|
|Atleti cannot rely on set-pieces, says Suarez|
|Martinez: Baines at another level|
|Juan: Inter must maintain hunger|
|Van Gaal: Three month comment was stupid|
|Bielsa proud to equal Marseille record|
|Redknapp: No one could do better than me|
|Manolas: I rejected Juve and Arsenal for Roma|
|Winning without Costa delights Mourinho|
|Mannone vows to repay fans|
|Balotelli ´doing his best´, insists Rodgers|
|Marseille feeling streak fatigue|
|Fournier hails substitutes´ influence|
|Copa Sudamericana Preview: River wary of Libertad|
|Colombian Primera A Review: Santa Fe stay top, Medellin lose|
|Valencia must bounce back - Nuno|
|Ecuadorian Primera A Review: Blanco inspires Barcelona|
|Liga del Futbol Profesional Boliviano Review: Wilstermann go top, Blooming slip up|
|MLS Review: Sounders deny Galaxy, Donovan|
|Venezuelan Primera Division Review: Caracas continue rise, Tachira stumble|
|Uruguayan Primera Division Review: Alonso´s brace inspires rampaging Nacional|
|Inter behind Mazzarri - Ausilio|
|Peruvian Primera Division Review: Alianza Lima leapfrog Union Comercio|
|Benitez happy with second half|
|Costa Rican Primera Division Review: Alajuelense jump clear, Saprissa win fifth straight|
|Liga MX Review: Leon continue resurgence|
|Brazilian Serie A Review: Cruzeiro, Sao Paulo bounce back|
|Hart: Aguero ´useless´ in training|
|Inter´s season starts now - Hernanes|
|Lopez rues lack of concentration|
|Serie A Review: Honda inspires Milan, Inter held|
|Ligue 1 Review: Marseille extend lead, Lyon put five past Montpellier|
|Inter 2 Napoli 2: Hernanes rescues a point|
|Maran appointed new Chievo boss|
|Bundesliga Review: Hoffenheim still unbeaten, Paderborn back to winning ways|
|Hughes ´disappointed´ by Moses criticism|
|Eredivisie Review: Cambuur fight back to share derby spoils, Go Ahead win thriller|
|Furious Monk urges Moses punishment|
|Taarabt not fit to play football - Redknapp|
|Rodgers relieved with Liverpool victory|
|Monk blasts referee over Stoke penalty|
|Defeat an ´absolute injustice´ for Redknapp|
|CSL Review: Evergrande close in on title, Harbin Yiteng relegated|
|Indian Super League Review: Moritz inspires Mumbai in Pune pummelling|
|Stoke City 2 Swansea City 1: Substitute Walters heads home winner|
|Thai Premier League Review: Chonburi close gap on leaders Buriram|
|Inzaghi seeking defensive improvements|
|Porto v Athletic Bilbao: Lopetegui expecting tough test|
|BATE v Shakhtar Donetsk: Visitors in upbeat mood ahead of UEFA Champions League test|
|Schalke v Sporting Lisbon: Draxler warns more is to come|
|Chelsea v Maribor: Mourinho to resist urge to chop and change|
|Gerrard ´in shock´ after Liverpool snatch late win|
|Verona 1 Milan 3: Honda brace seals victory|
|QPR 2 Liverpool 3: Caulker own goal gives visitors victory after late drama|
|Simeone praises Griezmann impact|
|Chievo sack Corini|
|Barcelona v Ajax: Mascherano calls for focus|
|APOEL v Paris Saint-Germain: Visitors battling injury crisis|
|Ribery hoping to get back to best|
|LFP to investigate Nice-Bastia clash|
|Allardyce lauds front two|
|Roma v Bayern Munich: Destro raring to go|
|Atletico Madrid 2 Espanyol 0: Simeone´s men take the points|
|CSKA Moscow v Manchester City: Pellegrini welcomes pressure|
|Winger is a Tad special - Koeman|
|Ancelotti dismisses Sterling speculation|
|K.League Review: Jeonbuk go seven points clear at top|
|Poyet expects response after eight-goal thrashing|
|Oscar coming of age at Chelsea|
|Warnock eyes brighter future for Zaha|
|Garcia relishing Bayern clash|
|Martinez commends Alcaraz|
|Pellegrini sounds Aguero warning to opposition|
|A-League Review: Villa rescues City again, Perth Glory top after late drama|
|MLS Review: DC wrap up Eastern Conference|
|Vidal slams media ´lies´|
|CONCACAF Champions League Preview: Porter wants Portland focus|
|Roma refocus on Bayern|
|Clean sheet pleases Di Matteo|
|Durm withdraws with thigh strain|
|We deserved more - Valverde|
|La Liga Review: Barca, Real win easily|
|Pelle: We had to keep going|
|Draw changes nothing - Allegri|