Monaco have lost ground on Ligue 1 leaders Paris Saint-Germain over the last month and need to respond against Toulouse on Sunday.
A home loss to relegation-threatened Valenciennes in December was followed by a 1-1 draw at Montpellier last week.
And champions PSG capitalised on the slip-up made by Claudio Ranieri's side, as they surged five points clear at the top of the table with victory at Ajaccio last time out.
Toulouse are in good Ligue 1 form, unbeaten in six, and won 1-0 at Bordeaux on Saturday - a result that lifted them to 10th in the table.
Monaco striker Radamel Falcao has battled injury issues this season and has scored just once in his last four matches for the club, with Ranieri desperate for the Colombian forward to find form.
PSG host sixth-placed Nantes on Sunday and will be buoyed by their 3-1 Coupe de la Ligue win at Bordeaux on Tuesday.
Goals in the last five minutes from Adrien Rabiot and Blaise Matuidi helped the capital club into the last four, as their bid for a domestic treble gathered pace.
PSG won 2-1 at Nantes earlier this season thanks to Ezequiel Lavezzi's late strike and will enjoy returning to Parc des Princes, where they have not lost in the league since November 2012.
Third-placed Lille are now just two points behind Monaco and take their outstanding record to Saint-Etienne on Friday.
Lille have conceded just 10 goals in 20 Ligue 1 matches and will hope to make the most of Saint-Etienne's humiliating Coupe de France exit at fourth-tier Cannes on Tuesday.
Saint-Etienne, who sit fourth, had the chance to win the penalty shootout that followed a 1-1 draw, but lost their nerve as Cannes celebrated a famous triumph.
Marseille host troubled Valenciennes on Saturday, with the latter facing the prospect of being administratively relegated at the end of the season if their financial problems continue.
They might drop to Ligue 2 on form anyway, but victories in their last two league matches have boosted spirits and seen them rise to 18th.
Other fixtures on Saturday see Bastia take on Bordeaux, Lorient battle Guingamp and Nice face Ajaccio.
There are also matches between Rennes and Evian TG, and Sochaux and Montpellier, while a slowly-improving Lyon hit the road to face Reims on Sunday.
|4||J. Akpa Akpro|
|10||W. Ben Yedder|
|Coach: A. Casanova|
for W. Ben Yedder 69'
for E. Didot 80'
|Juventus unveil dramatic change to club logo - but not everyone´s a fan|
|´I do not think I will return to coaching´ - Van Gaal set to call it quits|
|Torino 2 AC Milan 2: Bacca caps thrilling comeback as hosts pay the penalty|
|DR Congo 1 Morocco 0: Kabananga pounces on blunder to give 10 men the points|
|´Happy and comfortable´ Sanchez dismisses Arsenal exit talk|
|How much?! West Ham flop Simone Zaza could cost Valencia €20m|
|Mali v Egypt: Salah leads Pharaohs´ bid for AFCON glory|
|Sevilla concede they ´cannot force´ sporting director Monchi to stay|
|Ivory Coast 0 Togo 0: Reigning champions held to opening draw by Adebayor and co.|
|Goalkeeping woes, Stones and tactical confusion - How Guardiola is making life difficult for himself|
|Ozil and Sanchez can be persuaded to stay - Cech|
|Pogba: I rejected Barcelona and Real Madrid|
|Ghana v Uganda: Gyan dreams of first trophy since 1982|
|Chiellini: Juventus a work in progress|
|Robben agrees Bayern renewal until 2018|
|Hazard: Goals do not matter to me|
|Bennell pleads not guilty to eight child sex offences|
|Muller fed up with debate over Bayern role|
|Wenger glad Sanchez is not ´a Costa problem´|
|Flick resigns as DFB´s sporting director|
|Gomis ´can´t wait´ to welcome Payet to Marseille|
|Chinese FA changes foreign player rules after ´irrational´ spending|
|Like father, like son: Justin Kluivert follows in dad´s footsteps|
|´No reason to lose him´ - Marotta rubbishes talk of Allegri exit|
|Courtois: We don´t need Costa|
|Kane: Tottenham players won´t go to China|
|Noble ´angry and disappointed´ with Payet|
|Klopp furious over Matip uncertainty|
|Wenger surprised by tight Premier League|
|´Money is not everything´ - Conte issues warning amid China speculation|
|Fiorentina defeat a ´bad setback´ - Allegri|
|´This will elevate this group of players´ - Sampaoli revels in Sevilla late show|
|WATCH: Rio Ferdinand screams and dances in crazy Man Utd celebration|
|Real Madrid relaxed, admits Zidane after Sevilla defeat|
|Monaco go top of Ligue 1 with stunning Marseille victory|
|Ronaldo equals LaLiga penalty record as Real Madrid lose|
|Sevilla 2 Real Madrid 1: Stunning late comeback ends unbeaten run at 40|
|Fiorentina 2 Juventus 1: Brilliant Viola breathe life into Serie A title race|
|Tunisia 0 Senegal 2: Mane on target as favourites start strongly|
|Mourinho explains Klopp confrontation|
|Klopp delights in Alexander-Arnold display|
|Algeria must cut out mistakes against Tunisia - Leekens|
|Long balls led to Man Utd equaliser, says Klopp|
|´We attacked, Liverpool defended´ – Mourinho insists a point flattered Klopp´s men|
|DR Congo v Morocco: ´Confidence´ the Atlas Lions´ biggest hindrance ahead of AFCON opener|
|Ibrahimovic: Direct tactics worked for United|
|Guardiola rues gap to Chelsea after Goodison mauling|
|Algeria 2 Zimbabwe 2: Mahrez double prevents shock defeat|
|Manchester United 1 Liverpool 1: In-form Ibrahimovic saves hosts|
|Ivory Coast v Togo: AFCON champions hope to tame Le Roy´s ´troublemakers´|
|Guardiola lays City´s mental frailties bare after Goodison rout|
|Koeman hails ´perfect´ Everton after City mauling|
|Nice stalemate gives Monaco chance to go top|
|Guardiola suffers heaviest league loss in Everton thrashing|
|Neymar-esque Zaha is England´s loss – Bolasie|
|Everton 4 Manchester City 0: Koeman leaves old pal Guardiola´s title bid in tatters|
|Matip withdrawn from Liverpool selection over eligibility questions|
|Podolski staying at Galatasaray, insists sporting director|
|Cavani wants PSG stay|
|Torino move feels normal now – Hart|
|Chinese FA changes rule on CSL foreign players - reports|
|Bayern complete swoop for Hoffenheim duo Sule and Rudy|
|Aubameyang: Dortmund not really like Barca, Madrid or Bayern|
|Pogba can chance a game in one second - Herrera|
|Newcastle Jets 2 Perth Glory 2: Keogh´s eighth of season seals draw|
|Klopp: Liverpool ready for Old Trafford test|
|Herrera taunts Liverpool ahead of Old Trafford showdown|
|I had to be 100 per cent to stay at Boca - Tevez|
|No player is bigger than the club - Carroll takes swipe at want-away Payet|
|Icardi: I can always move to China at end of career|
|Mkhitaryan: Klopp convinced me not to join Liverpool|
|Mourinho: Pogba can score every game|
|Cameroon´s profligacy frustrates Broos|