Milan began life without Massimiliano Allegri by recording a 3-1 Coppa Italia round of 16 victory at home to Spezia on Wednesday.
Allegri was sacked by the San Siro outfit on Monday after a series of dismal results left the club languishing in the bottom half of Serie A, with Clarence Seedorf set to be confirmed as his replacement.
Coach Mauro Tassotti has taken caretaker charge in the meantime, and will have been pleased with what he saw as Giampaolo Pazzini - making his first start since April - inspired Milan to qualification for the quarter-finals.
The forward provided the assist as Robinho broke the deadlock with a headed effort in the 28th minute, before Pazzini himself doubled the advantage with a volley three minutes later.
And Milan were three up two minutes after the break, as Keisuke Honda reacted quickest to a Nicola Leali parry from a Riccardo Montolivo effort to net his first goal for the club.
New boss Seedorf arrived in the stands in time to watch the last 20 minutes, but the only goal he saw was a stoppage-time consolation strike for Milan's second-tier opponents courtesy of Nicola Ferrari.
Lorenzo Insigne and Jose Callejon spared Napoli's blushes as Rafael Benitez's men battled from a goal down to beat 10-man Atalanta 3-1 and set up a quarter-final clash against Lazio.
Giuseppe De Luca handed Atalanta a shock 14th-minute lead at Stadio San Paolo, but Callejon restored parity almost immediately.
Insigne put Napoli ahead in bizarre circumstances with 18 minutes remaining. A chipped ball forward to Gonzalo Higuain, standing offside level with the penalty spot, bounced back off the defender and into the path of Insigne, who smashed it into the bottom corner to spark angry protests from the Atalanta players.
Mario Yepes was sent off for dissent as the aftermath to Insigne's controversial goal rumbled on. Callejon then compounded Atalanta's misery by netting Napoli's third.
In the day's early kick-off, second-tier side Siena pulled off a shock 4-1 victory at Serie A's bottom club Catania.
Sebastian Leto put the hosts ahead inside the opening five minutes, but Michele Paolucci equalised for Siena to send the sides in level at the break.
Francesco Valiani's glancing effort on the hour mark put the visitors in front, and stoppage-time goals from Nico Pulzetti and Valerio Rosseti made sure of their progression to the last eight.
|2||M. De Sciglio|
|10||K. Honda||18' 47'|
|Coach: M. Tassotti|
for K. Honda 64'
for G. Pazzini 71'
for Robinho 78'
|Ba left out of Senegal AFCON squad|
|Redknapp frustrated by penalty call|
|Wenger sees Giroud wrongs|
|Premier League schedule a ´disgrace´, says Poyet|
|Championship Review: Bournemouth stay top, Heskey scores on Bolton debut|
|Hughes lauds Bojan performance|
|Koeman: Saints marching on|
|Pardew rues referee error|
|Arsenal 2 QPR 1: Sublime Alexis secures the spoils|
|Martinez questions Walters decision|
|Poyet laments Sunderland mistakes|
|League One Review: Swindon cruise to win over Walsall|
|Irvine aware of need for improvement|
|United still doing ´very bad things´ - Van Gaal|
|Lambert proud of players despite Swansea defeat|
|Warnock bemoans Palace defence|
|Bruce hails Hull´s spirit|
|Pochettino relieved to come away with victory|
|Dyche: We had our pocket pinched|
|Monk hails Fabianski performance|
|Pearson demands greater concentration from Leicester|
|Kompany set for City return|
|Rodgers hails character after battling win|
|League Two Review: Ainsworth frustrated by Luton, Shrewsbury go top|
|Everton 0 Stoke City 1: Lacklustre Everton slip to defeat|
|Sunderland 1 Hull City 3: Triumphant return for Bruce|
|Burnley 0 Liverpool 1: Sterling wins it at Turf Moor|
|Leicester City 1 Tottenham 2: Eriksen piles misery on Pearson´s men|
|Manchester United 3 Newcastle United 1: Rooney extends hosts´ streak|
|West Brom 1 Manchester City 3: Three and easy for in-form champions|
|Swansea City 1 Aston Villa 0: Hosts break Boxing Day duck|
|Crystal Palace 1 Southampton 3: Mane marks return with star performance|
|Allardyce upbeat despite defeat|
|Van Dijk happy at Celtic - Deila|
|Table-topping Chelsea delight Mourinho|
|Chelsea 2 West Ham 0: Mourinho´s men ease to victory|
|Suarez enjoying Messi, Neymar link-up|
|A-League Review: Garcia rescues point for Perth, Adelaide up to second|
|Poyet calls for mid-season break|
|Van Gaal rules out Januzaj move|
|Rodgers: Balotelli may have to get used to bench|
|Lallana: I was trying too hard|
|Walker juggles music, football careers in Sweden|
|Song to face ´brother from another mother´ Fabregas|
|Adriano announces Le Havre deal|
|Pardew braced for Old Trafford test|
|Lescott unfazed by City reunion|
|Tskhadadze appointed Georgia coach|
|United to finish top three - Ferdinand|
|Allardyce: Stamford Bridge stalemate saved my job|
|Southampton need three January signings, says Watson|
|Liverpool can make Champions League, says fanzine editor|
|Walsh: Hull clash crucial for Leicester|
|Toure, Aubameyang and Enyeama make shortlist for African gong|
|Docherty backs Chelsea to win two-horse race|
|Liverpool could benefit from Hyypia influence - Scales|
|Saudi Arabia name Asian Cup squad|
|Forty-year-old Cahill no problem for Postecoglou|