America head coach Antonio Mohamed needs his side to turn their form around in Liga MX, which includes a top-of-the-table clash this round.
The 11-time league champions and Clausura winners in 2013, America have suffered three straight league losses to be sitting fifth ahead of their trip to Monterrey on Saturday.
Mohamed replaced now-Mexico coach Miguel Herrera at the end of the previous campaign but has struggled to get the most out of a side who lost the Apertura final to Leon.
Goals have been an issue in their losing run with just one in the past three matches and America need to improve at Monterrey.
Luis Gabriel Rey and Raul Jimenez have scored six of America's eight goals – in as many league games – this season.
Monterrey, who climbed away from the bottom of the table with a 1-0 win at Atlas last time out, will fancy their chances at home.
Cruz Azul, three points clear at the top and 10 ahead of America, are the only unbeaten side left ahead of their clash at home to Toluca.
It shapes as being a bigger clash for the visitors, who must avoid defeat if they want to stay in touch with the high-flying leaders.
Marco Fabian and Mauro Formica (four league goals each) have been in fine form for Cruz Azul, while Toluca have firepower of their own in Pablo Velazquez (five).
Third-placed Pumas UNAM host the side just below them on the table in Pachuca on Sunday with both hoping the top two play out a draw.
Struggling Tigres UANL travel to Guadalajara and seventh-placed Leon will be hoping for a strong result at Chiapas.
Santos Laguna host battlers Atlas, Queretaro travel to Puebla, Tijuana visit bottom side Veracruz and Morelia take on Atlante.
|Coach: C. Barra|
for E. Juárez 46'
for O. Arellano 63'
for R. Osorio 69'
|Del Bosque unmoved by calls for two strikers|
|Deschamps praise for beautiful France|
|Fekir ruptures knee ligaments|
|Italy v Bulgaria: Conte warns against complacency|
|Euro 2016 Qualifiers Review: Germany top Group D, Northern Ireland edge closer|
|Low: Three points most important|
|Northern Ireland on the verge of a ´magnificent achievement´ - O´Neill|
|Scotland need something against Germany - Strachan|
|Portugal 0 France 1: Late Valbuena set-piece clinches deserved win|
|Faroe Islands 1 Northern Ireland 3: O´Neill´s men edge closer|
|Germany 3 Poland 1: Gotze sends world champions top|
|Gibraltar 0 Republic of Ireland 4: Irish hopes reignited|
|Djibouti 0 Togo 2: Saintfiet´s side make it two wins from two|
|Cyprus v Belgium: Benteke boost for Wilmots´ men|
|Roma youngster faces lengthy lay-off|
|United hit back at Perez barb over De Gea saga|
|Georgia 1 Scotland 0: Strachan´s men succumb to Tbilisi hoodoo|
|Hodgson prepared to blood new players|
|Porto invite Euro elite to help raise millions for migrants|
|Dortmund legend Dede backs Tuchel to succeed|
|Robben out for four weeks|
|Turkey v Netherlands: Terim expecting hostile atmosphere for crunch clash|
|Portugal 0-1 France: Valbuena strikes late to sink Ronaldo & Co|
|Wales v Israel: Euro 2016 beckons for Coleman´s history boys|
|Gala: No extra payment for Grosskreutz|
|Increase Bundesliga´s TV rights or be left behind - Rummenigge|
|Kane: I´m no flash in the pan|
|Perez: United showed inexperience in De Gea saga|
|Milligan: Socceroos wary of Tajikistan|
|Conte wants more players like Pelle|
|OFC World Cup Qualifying Review: Samoa to meet Tahiti in next round|
|Krychowiak stayed at Sevilla because of Emery|
|I never considered Bayern exit - Gotze|
|Balotelli ´not in good condition´, Milan must improve - Mihajlovic|
|Robben slams ´stupid´ Martins Indi|
|Robben laments injury blow|
|Euro 2016 Qualifiers Review: Bale edges Wales closer, Iceland dent Netherlands´ qualification hopes|
|De Bruyne relieved to ´boss´ Bosnia-Herzegovina|
|Blind furious after nightmare debut|
|Coleman sees shades of Charles in Bale winner|
|Conte only concerned about Italy winning|
|Mauritania v South Africa: SAFA to investigate Masilela no-show|
|AFC World Cup Qualifying Review: Qatar hit 15 in Bhutan rout|
|Belgium 3 Bosnia-Herzegovina 1: De Bruyne shines in straightforward victory|
|Cyprus 0 Wales 1: Bale winner takes Wales one step closer|
|Netherlands 0 Iceland 1: Sigurdsson winner caps difficult first game for Blind|
|Italy 1 Malta 0: Pelle spares wasteful Azzurri|
|Balotelli stars in Milan friendly win|
|Bhutan thrashed 15-0 by Qatar in qualifier|
|Rwanda v Ghana: Gyan doubt gives hosts hope|
|Tanzania v Nigeria: Enyeama out of AFCON qualifier|
|Valdes and Berahino included in Premier League squads|
|Costa Rica v Brazil: Dunga´s men return after Copa disappointment|
|Spain v Slovakia: Azpilicueta eyeing important revenge|
|Adebayor left out of Tottenham squad list for league and Europe|
|San Marino v England: Place in history books beckons for Rooney|
|Germany can cope with Reus absence - Low|
|Bayern offer aid to refugees in ´training camp´|
|BREAKING NEWS: Welbeck ruled out for months after knee surgery|
|South Korea 8 Laos 0: Son leads the way in rout|
|Australia 5 Bangladesh 0: Socceroos surge to emphatic win|
|Japan 3 Cambodia 0: Hosts pick up first qualifying win|
|Rudiger aiming to nail down Euros spot after Roma move|
|Melo happy to join Inter at last|
|Hernandez thanks Ferguson after United departure|
|Chung: AFC has compromised FIFA election|
|Wales the new best of British|
|Reus out of Germany qualifiers|
|Chile v Paraguay: Vidal missing for Copa champions|
|Ghedin: Anything is possible for Malta|
|Pogba will be worth €100m - Marotta|
|England can win Euro 2016 - Hodgson tells players|
|Conte unsure over Balotelli future|
|Argentina - Bolivia Preview: Mascherano backs 'very special' Messi|
|Portugal - France Preview: Deschamps aiming to correct mistakes|