Bayern Munich represent daunting hosts on Saturday for a Schalke side seeking to bounce back from a mauling at the hands of Real Madrid.
The Gelsenkirchen outfit were subjected to a humiliating 6-1 thrashing by Real on Wednesday in the first leg of their UEFA Champions League last-16 tie.
Schalke had entered the fixture in confident mood, with Real having won only once in 25 previous visits to German opposition.
Yet Real are not top of La Liga by accident and a scintillating display from the Spanish side, which saw Karim Benzema, Gareth Bale and Cristiano Ronaldo all score twice, has seemingly put paid to any hopes Schalke have of reaching the quarter-finals.
Life is not likely to get any easier for Jens Keller's men when they travel to the Allianz Arena to face runaway Bundesliga leaders Bayern.
Pep Guardiola's charges have been simply unstoppable in Germany's top flight this season, and their relentless march towards a defence of the Bundesliga title shows no signs of being slowed.
The unbeaten Bavarians have dropped points on just two occasions this term thanks to a mix of irresistible attacking displays and defensive solidarity, highlighted by the fact Bayern boast comfortably the best offensive and defensive record in the league with 61 goals scored and just nine conceded.
Bayern may have swept opponents aside this term but goalkeeper Manuel Neuer, who was rested last weekend, has warned his team-mates not to underestimate the club he started his career with.
"Schalke are always a strong opponent. You know you have to be careful and you will never win easily against them. We are highly motivated and we need to have the right attitude for the match," he said.
Prior to their heavy defeat against Real, Schalke had displayed excellent form, winning five times in an unbeaten run of league games spanning seven matches.
However, Schalke have lost six games in a row against Bayern without scoring, conceding at least four in the previous three meetings between the teams.
Thomas Muller misses out for Bayern this weekend due to a hamstring injury, while the game could come too soon for Franck Ribery (thigh) and Xherdan Shaqiri (hamstring).
Schalke forward Julian Draxler made his first start since December against Real after an ankle injury and was able to complete the full 90 minutes.
|10||A. Robben||15' 28' 77'|
for M. Götze 70'
for B. Schweinsteiger 77'
for A. Robben 84'
|West Ham 3 Lusitans 0: Sakho nets twice at start of Europa League journey|
|Holebas makes Watford move|
|Milan secure Adriano signing|
|Peru v Paraguay: Diaz counts cost of semi-final loss|
|Bastia hit out at reports of extra debt|
|Hernandez has successful surgery|
|Odemwingie signs one-year Stoke extension|
|Uth signs for Hoffenheim|
|Henen seals Everton return|
|Cattermole pens long-term Sunderland deal|
|United States v Guatemala: Klinsmann backs Dempsey ahead of Gold Cup warm-up|
|West Ham working on Jenkinson return - Gold|
|Milan agree deal for Bacca|
|Real buy back Vazquez from Espanyol|
|Richards leaves Swansea for Fulham|
|McShane signs for Reading|
|Giggs tells youngsters to seize US chance|
|Hammond pens Leicester extension|
|Only Schweinsteiger can decide Bayern future - Guardiola|
|Cech plans to play until he´s 40|
|Montoya arrives in Milan ahead of Inter move|
|Hernandez out of Gold Cup|
|US asks Switzerland to extradite seven FIFA officials|
|MLS Preview: Sounders seek momentum switch|
|Mexico 0 Honduras 0: Hernandez injury sours friendly|
|Hernandez taken to hospital|
|Garay in doubt for Copa America final|
|Wambach: USA peaking for World Cup final|
|Bassett ´an absolute hero´ despite own goal - Sampson|
|Japan 2 England 1: Late own goal breaks English hearts|
|Salvo quits as Valencia president|
|Costa not Ribery cover - Bayern director Sammer|
|Chile, Argentina deserve final spots - Mena|
|Ramos keen on United switch - Calderon|
|B36 1 The New Saints 2: Wilde leaves it late to secure advantage|
|Sevilla agree deal for Rami|
|Celtic snap up United teenager Janko|
|Beauvue passes Lyon medical|
|Roma bring in Falque|
|Coates completes permanent Sunderland switch|
|Vallecano to make charity donations from shirt sales|
|Angella commits to Watford|
|Gundogan pens new Dortmund deal|
|Juve reject €80million Barca offer for Pogba, says Marotta|
|Ruiz seals permanent Villarreal move|
|Mourinho respects Cech´s decision to quit Chelsea|
|Claridge excited by potential Pearson successors|
|Miranda completes Inter switch|
|Blind takes over as Netherlands coach|
|Mourinho: Premier League tougher to win than ever|
|Hamburg make Holtby move permanent|
|Southampton terminate Osvaldo contract|
|BREAKING NEWS: Swansea swoop for Eder|
|Abbiati extends Milan stay|
|Cruyff: Barcelona have lost their values|
|Vydra seals Watford move|
|Ambitious Clyne targets trophy haul with Liverpool|
|Claridge: Off-field incidents cost Pearson his job|
|Clyne becomes Liverpool´s sixth close-season signing|
|Imbula leaves Marseille for Porto|
|FIFA chief Blatter challenges critics to prove corruption claims|
|Distin joins Bournemouth|
|Bayern seal Costa deal|
|Arsenal confirm Diaby departure|
|Blatter to miss Women´s World Cup final|
|Bogdan sets sights on being Liverpool number one|
|Danilo eager to get started at Real Madrid|
|Leicester´s Wood joins Leeds|
|Porto confirm Atletico move for Martinez|
|Lloyd: Repetition key to netting penalty|
|Sheffield Wednesday job a ´dream´ for Carvalhal|
|´We played a complete game´ - Messi|
|Diaz upbeat despite heavy Copa loss to Argentina|
|Martino lauds Messi for selfless performance|
|Viviani makes surprise Verona switch|
|Estonian team wins cup match 31-0|
|No meeting with Arsenal has occurred - Vidal´s agent|
|United States 2 Germany 0: Ellis´ team reach World Cup final|
|Argentina 6 Paraguay 1: Messi leads Martino´s men to Copa final|
|UEFA Europa League Review: FK Zeljeznicar and FC Dacia Chisinau open with wins|
|UEFA Champions League Review: FC Pyunik make winning start|