Universidad de Chile could move three points clear at the top of Group 5 in the Copa Libertadores when they travel to Cruzeiro on Tuesday.
Cruzeiro lost their opening Copa Libertadores match 2-1 to Peru's Real Garcilaso and have yet to start the Brazil Serie A season, while Universidad are already eight rounds into their Chile Primera Division campaign.
Universidad have only lost once this year but head coach Cristian Romero will want his team to tighten up defensively ahead of their trip to Brazil, after watching them come from behind to draw 3-3 at Audax Italiano on Friday.
Having taken the lead in the third minute of their league encounter in Santiago de Chile, Universidad conceded three times before the hour-mark.
But goals to Patricio Rubio, who has scored in Universidad's past two matches, and Francisco Castro ensured Romero's men claimed a point and extended their unbeaten run to three games.
Rubio's goal against Audax Italiano was a fine piece of centre forward work, as he found a pocket of space on the edge of the area, turned his marker to receive the ball facing the goal and burst forward, before chipping the opposition goalkeeper from a tight angle.
If Universidad defeat Cruzeiro on Tuesday, they will move to six points after a 1-0 win over Defensor Sporting of Uruguay on the opening matchday.
Defensor and Garcilaso both have three points after the former defeated the latter 4-1 last week.
While the Brazil Serie A has not resumed this season, Cruzeiro have played since their loss to Garcilaso in the Minas Gerais state championship, drawing 0-0 with reigning Copa Libertadores champions Atletico Mineiro before wins over Guarani MG and Boa.
In Group 7, Emelec will also have a lot to play for as they travel to Brazil on Wednesday with a win at the Maracana against Flamengo set to take the Ecuadorian club to the top of the standings.
Emelec (three points) sit second in Group 7, one point behind Mexico's Leon (four), who drew 1-1 with Bolivar (one) last week.
Flamengo (zero) lost 2-1 at Leon on matchday one, while Emelec defeated Bolivar 2-1.
The Ecuadorian champions won their local derby against Barcelona 2-1 on Saturday and have not lost in 19 competitive fixtures, while Flamengo have won three in a row in the Rio de Janeiro state championship since their loss in Mexico.
Four other Brazilian clubs will also be in action this week with Group 1 leaders Atletico Paranaense to travel to Velez Sarsfield of Argentina, Gremio will host Colombia's Atletico Nacional in Group 6, Group 2's top team Botafogo will head to Chile to play Union Espanola and Mineiro also face Colombian opposition in Group 4 in the shape of Santa Fe.
Argentina's San Lorenzo and Newell's Old Boys will complete the week's Copa Libertadores action on Thursday with games against Independiente del Valle of Ecuador and Uruguay's Nacional, while in other matches, Arsenal take on Deportivo Anzoategui on Tuesday and Cerro Porteno will host Lanus on Wednesday.
|28||Ricardo Goulart||34' 43' 85'|
|Coach: Marcelo Oliveira|
for M. Martins 64'
for Dagoberto 75'
for Everton Ribeiro 78'
|Mason in stable condition after skull fracture|
|Senegal v Algeria: Misfiring favourites in last-chance saloon|
|PSV provide perfect finish for darts champ Van Gerwen|
|Broos predicts ´something great´ for Cameroon|
|Eibar 0 Barcelona 4: MSN see Barca to victory after Busquets blow|
|Busquets sustains ankle ligament damage in Eibar v Barcelona|
|Cameroon 0 Gabon 0: Aubameyang miss haunts hosts as AFCON campaign ends|
|Guinea-Bissau 0 Burkina Faso 2: Traore on target as Stallions advance|
|Busquets injury at Eibar compounds Barcelona midfield woes|
|Deulofeu lands in Italy ahead of AC Milan move|
|´I made the best decision´ - Conte basks in Costa recall|
|Wenger urges Xhaka not to ´punish´ Arsenal|
|Ex-Bastia man Palmieri questions Balotelli racial abuse claims|
|Costa reaction hailed by Cahill|
|Manchester City must be mentally strong, says embattled Bravo|
|Chelsea 2 Hull City 0: Costa back with a bang for Blues|
|Koke lauds Griezmann ´stroke of genius´ as Atletico snatch draw|
|Pioli questions Ansaldi dismissal|
|´I should have shut up and I apologise´ - Wenger sorry for ref rant|
|Arsenal can be proud of this red-card record|
|Mustafi: Arsenal never give up|
|Higuain: Lazio posed no threat to Juventus|
|Athletic Bilbao 2 Atletico Madrid 2: Griezmann magic rescues point|
|Puel unsure Van Dijk will be fit for Liverpool clash|
|Free-scoring Monaco return to Ligue 1 summit|
|Arsenal 2 Burnley 1: Sanchez snatches thrilling win for 10-man Gunners|
|Palermo 0 Inter 1: Joao Mario strike extends Inter streak|
|Arsenal fans give Alexis Sanchez paws for thought|
|Costa returns to Chelsea XI to face Hull City|
|Inter cannot delude fans about Messi - Ausilio|
|Allegri admits new Juventus formation was a ´mad idea´|
|Leicester boss Ranieri admits to tactical mistakes|
|Zimbabwe v Tunisia: Kasperczek demands ruthlessness with quarter-final spot on the line|
|Southampton 3 Leicester City 0: Saints end losing streak but suffer potential Van Dijk blow|
|Juventus 2 Lazio 0: Dybala and Higuain strikes see leaders return to form|
|Iborra makes a mark at both ends as Sevilla scrape past Osasuna|
|Pogba hails ´brother´ Griezmann as Manchester United speculation continues|
|Costa fight rumour ´not nice´, says Courtois|
|Henry makes emotional Ozil plea: Stay and become an Arsenal legend|
|Welbeck still has huge promise, says Wenger|
|A-League Review: Wanderers finally end home hoodoo|
|Tevez denies he´s highest-paid player after CSL move|
|Napoli capable of greatness - Sarri|
|Montella proud of Milan display against Napoli|
|Ramos tells Madrid fans: We need support|
|Conte: Costa committed to Chelsea|
|Callejon credits ´Maradona effect´ as Napoli down AC Milan|
|Uganda didn´t deserve to lose - Sredojevic|
|Lloris kept us in the game - Pochettino backs captain despite errors|
|Guardiola ´never going to give up´ on Premier League title|
|Chapecoense make emotional return to football|
|Allardyce: Players don´t want to join Palace relegation fight|
|Pulis backs Berahino to get back on track at Stoke|
|AC Milan 1 Napoli 2: Callejon settles San Siro thriller|
|Guinea-Bissau v Burkina Faso: Cande not thinking about going home|
|Egypt 1 Uganda 0: El Said to the rescue for Pharaohs|
|Gabriel Jesus delighted to make Premier League bow|
|England boss Southgate lauds record-breaker Rooney|
|Leipzig beat Frankfurt to cut Bayern´s lead|
|Guardiola blasts missed chances, not referee, after Spurs draw|
|Candid Pochettino says City were unlucky not to beat Spurs|
|AC Milan ´still negotiating´ over Deulofeu|
|Ben Arfa content with striker role at PSG|
|Walker admits to Sterling push in contentious City-Spurs draw|
|Emery hails PSG personality after tricky Nantes test|
|Manchester City 2 Tottenham 2: Controversial Son strike bails out Lloris|
|Record-breaking Rooney: Lineker, Shearer and wife Coleen lead Twitter tributes|
|Knee surgery to end Ogbonna season - Bilic|
|Karanka hits out at ´awful´ Riverside atmosphere|
|Zidane urges Madrid fans to stick with Ronaldo and Benzema|
|Palace players not to blame for last-gasp defeat, claims Allardyce|
|Zidane frustrated as Marcelo and Modric add to Madrid´s injury worries|
|Howe praises Bournemouth ´fighters´ after Watford draw|
|Poor goals a disease for Sunderland - Moyes|
|Charlton, Ferguson hail ´true great´ Rooney|
|Tuchel annoyed by ´sluggish´ Dortmund|
|Mourinho: Rooney now a Manchester United legend|
|Ghana 1 Mali 0: Gyan heads Black Stars into quarter-finals|
|Nantes 0 Paris Saint-Germain 2: Cavani at the double as champions close on Nice|
|Better at Old Trafford, prolific against Arsenal - Rooney´s record in Opta numbers|
|Rooney: Record means a hell of a lot but I´m still disappointed|
|Fener free-kick to derby delight - Rooney´s top 10 Manchester United goals|
|Rooney merits place in history, forget the present and future struggles|
|Crystal Palace 0 Everton 1: Coleman late-show extends Allardyce´s losing run|
|Real Madrid 2 Malaga 1: Ramos double gets leaders back on track|
|Stoke City 1 Manchester United 1: Record-breaking Rooney snatches draw|
|West Brom 2 Sunderland 0: Baggies inflict more misery on Moyes´ men|
|Bournemouth 2 Watford 2: Hosts come from behind twice|
|Middlesbrough 1 West Ham 3: Rejuvenated Carroll makes the difference|
|Rooney becomes Manchester United´s all-time top goalscorer|
|Werder Bremen 1 Borussia Dortmund 2: Piszczek winner denies fightback|
|Cameroon v Gabon: Hosts look to avoid early exit|
|Swansea worthy winners at Anfield - Clement|
|Rummenigge defends Guardiola: Manchester City simply not as good as Bayern|
|Swansea had perfect gameplan, says match-winner Sigurdsson|
|Klopp baffled by sloppy Liverpool|
|Henry: Arsenal don´t need Payet – they have Iwobi|
|Allegri: Juventus have not lost their quality all of a sudden|
|Liverpool 2 Swansea City 3: Llorente and Sigurdsson stun Anfield|
|Nainggolan as valuable as Pogba - Spalletti|
|Atletico criticism excites Simeone|
|Luis Enrique worried about Eibar´s pitch|
|Januzaj: Pogba wants me back at Manchester United|
|There is nobody like him – Luis Enrique rues Iniesta absence|
|Mourinho: United need De Gea and Romero to stay|
|Chiellini: Sixth successive title would make Juventus players legends|
|A-League Review: Taggart fires Perth to glory|
|Balotelli furious after alleged racial abuse at Bastia|
|Tottenham stronger than previous seasons - Eriksen|
|Wenger prepared for 17 cup finals to overhaul Chelsea|
|Maldini: Donnarumma can emulate my Milan success|
|Klopp urges Liverpool to enjoy title race|
|Shaw going through ´difficult period´ - Mourinho|
|Klopp not worried by Sturridge, Origi form|
|De Gea backs ´amazing´ Pogba|
|Pochettino: Tottenham bigger than City|
|Conte: I trust Diego Costa 100 per cent|
|Lewandowski admits he was lucky for Bayern winner|
|City as sharp as Barca and Bayern but lacking consistency, says Guardiola|