Bayern Munich overcame 10-man Arsenal 2-0 on a UEFA Champions League night of high drama and missed penalties at the Emirates Stadium.
Arsene Wenger's surprise decision to start Yaya Sanogo ahead of Olivier Giroud appeared inspired as the pace of the French youngster and recalled Arsenal winger Alex Oxlade-Chamberlain unsettled Europe's tightest defence in the opening stages, only for Mesut Ozil to spurn a ninth-minute spot-kick.
Wojciech Szczesny then brought down Arjen Robben eight minutes before the break at the other end and was sent off, although David Alaba's resulting penalty struck the post for the second missed spot-kick of the game.
Following that, Munich laid siege to the Arsenal goal and they finally got their reward via a strike from the magnificent Toni Kroos, before substitute Thomas Muller put them firmly in control of the tie with a late second.
Szczesny will miss the return match in Munich and may also find himself in hot water with UEFA after appearing to make an offensive gesture when leaving the field after being shown his red card.
Bayern had stunned Manchester City with early goals in both their group-stage games against Arsenal’s Premier League counterparts and Kroos almost repeated the trick when he sent a 25-yard effort arrowing for the top corner in the second minute.
Szczesny, though, made a fine fingertip save and Arsenal went on to pin back their illustrious opponents during the opening exchanges.
Manuel Neuer stopped Sanogo from giving Arsenal reward for their early endeavour as he produced an excellent reaction stop following Jack Wilshere's prodded pass towards the striker.
Wilshere then released Ozil and Jerome Boateng - who endured a particularly torrid start - felled his Germany international team-mate in the area. But Ozil failed to capitalise from 12 yards as Neuer pushed away a tame effort.
That disappointment checked Arsenal's momentum, although Neuer had to rush out and deny Oxlade-Chamberlain in the 24th minute when the winger got the better of Alaba on the end of Sanogo's raking pass.
Arsenal left-back Kieran Gibbs departed with a hamstring problem after half an hour and replacement Nacho Monreal did not get up to speed quickly enough.
Robben raced past a static Monreal onto a delightful chipped pass from Kroos in the 37th minute and Szczesny charged out and brought the Dutchman down.
A lengthy delay followed and, although Alaba sent replacement Lukasz Fabianski the wrong way, his penalty rattled the base of the post.
Predictably, Bayern began the second half firmly on the front foot as Thiago Alcantara narrowly failed to connect with a cross from the left and Kroos drilled a low shot at substitute goalkeeper Fabianski.
Laurent Koscielny then stabbed goalwards from Ozil's 51st-minute free-kick but it was a moment of brief respite and the visitors led three minutes later, Kroos curling into the top corner from 20 yards.
Fabianski then saved twice from Robben and Muller almost found a decisive touch to cap the latest rampage from Rafinha in the 66th minute.
By now the attacks were relentless and when Muller stooped to head a deserved second with two minutes left it was no more than Bayern deserved.
They could even have added a third when Kroos rattled the post as Bayern looked to pile on the misery.
|Coach: A. Wenger|
for K. Gibbs 31'
for Santi Cazorla 39'
for A. Oxlade-Chamberlain 74'
|Ronaldo: Madrid would be smart to give me a new deal|
|Varane disappointed by Euros absence|
|Republic of Ireland v Netherlands: O´Neill wants confident display|
|Ronaldo shakes off injury in Real Madrid training|
|Atletico star Griezmann ´listening to different clubs´|
|United States - Ecuador Preview: Klinsmann pins hopes on Yedlin as Copa preparations continue|
|Gold tells Middlesbrough to ´dream on´ over Antonio|
|Schweinsteiger wants Mourinho to spice up Manchester derby|
|England v Australia: All eyes on Rashford debut|
|Aggressive Premier League better for me - Xhaka|
|Schweinsteiger ´right on schedule´ for Euro 2016|
|Darmian relishing Euros after return from injury|
|Northern Ireland v Belarus: Last chance to impress as O´Neill prepares to trim squad|
|Ventura leaves Torino amid Italy talk, Mihajlovic appointed|
|Sevilla confident of keeping Emery|
|Godin wants Atletico to use 2014 defeat as inspiration|
|Xhaka agrees Arsenal move|
|Idolisation of Ibrahimovic warranted Sweden captaincy - Hamren|
|Scholes hopes Mourinho keeps Giggs at Manchester United|
|Gotze snubbing Liverpool will boost Germany - Bierhoff|
|Bosz honoured by Ajax appointment|
|Ramos highlights Griezmann threat|
|Record-chasing Ronaldo and taming the Wolves - Real Madrid´s route to the Champions League final|
|Donnarumma dreams of being Milan captain|
|Koke: History, not revenge motivating Atletico|
|Costa Rica v Venezuela: Hosts ramp up preparations for maiden Copa America tilt|
|Argentina v Honduras: Messi and co warm up for Copa America|
|USA will win a World Cup, says Donovan|
|Pumas UNAM 2 Independiente del Valle 1 (3-3 agg, 3-5 on penalties): Hosts suffer shoot-out heartbrea|
|Gracia leaves Malaga as Rubin Kazan loom|
|Messi: Argentina deserve to be Copa America champions|
|Dybala included in Argentina´s preliminary Olympics squad|
|Mourinho and United a ´good wedding´ - Ancelotti|
|Klinsmann: Copa America better than Euros|
|Messi: Joining Barcelona not an easy decision|
|Carrico receives four-game ban for homophobic slur|
|Dani Alves wants Atletico to win Champions League|
|McNair out to impress ´world-class´ Mourinho|
|Ranieri: Premier League survival is Leicester´s priority next season|
|Argentina forward Lavezzi suffers hamstring scare|
|Koeman talks ´very positive´, say Southampton|
|Rami replaces injured Varane in France´s Euro 2016 squad|
|Matthaus applauds Gotze for rejecting ´easy solution´ of Liverpool|
|Suarez silenced his doubters - De Boer|
|AFC Champions League Review: Jeonbuk, Shanghai SIPG progress|
|Klopp can take Liverpool right to the top, says McAllister|
|Lindelof happy at Benfica amid Real Madrid, Barcelona links|
|Zidane is perfect on and off the pitch - Lippi|
|Bale: Zidane has brought the best out of Real Madrid|
|Favre takes over as Puel and Nice part ways|
|Liverpool complete Karius deal|
|Van Gaal was treated poorly by United, but Mourinho will be a success - De Boer|
|Dani Alves: I have won more titles than Pele|
|I know who I´m taking - Conte sure on Euro 2016 selection|
|Xavi backs Guardiola to ´change the face of English football´|
|Lucescu appointed Zenit boss|
|Manchester United and Liverpool hit with €40,000 fines|
|Weinzierl: I have nothing to lose at Schalke|
|Rangers complete Barton signing|
|Italy better placed as underdogs ahead of Euro´s - Motta|
|Cantona: I love Mourinho, but he is not Manchester United|
|Ben Arfa wants Lyon move - Aulas|
|David Silva praises Iniesta´s Copa del Rey heroics|
|´It was a little scare´ - Ronaldo plays down injury fears|
|Eder the real deal for Lille|
|Van Gaal treated unfairly during Manchester United spell - Daley Blind|
|Ginola doing ´very well´ after heart surgery|
|Depay rules out Manchester United exit following Van Gaal departure|
|Hojbjerg confirms desire to leave Bayern|
|Ronaldo leaves Madrid training early after knock|
|Abbiati unimpressed with Milan players´ attitude|
|Pepe calls on Madrid to continue making history|
|Ayestaran signs two-year deal with Valencia|
|Montolivo, Antonelli sign new AC Milan contracts|
|Ronaldo ready for UCL final after being rested from practice match|
|Hummels, Sanches deals will not stop Bayern spending - Rummenigge|
|Oblak´s penalty heroics, Griezmann´s Barcelona brace - Atletico Madrid´s route to the Champions Leag|
|Salvio all but confirms Gaitan will join Atletico Madrid|
|Motta warns PSG over Ronaldo, Neymar interest|
|Europa League Mourinho´s best hope for United trophy - Sheringham|
|Injustice if Iniesta never wins a Ballon d´Or - Del Bosque|
|Van Gaal didn´t deserve United sacking - Blind|
|I´ll be happy if we make Euro 2016 semi-finals - Del Bosque|
|Koke: Why would I want to leave Atletico?|
|Fofana could retire aged 25 - Lyon president|
|Sandro set to leave Barcelona|
|Silva plays down injury worries ahead of Euro 2016|
|United would be brave to appoint Mourinho, says Schmeichel|
|Neymar adamant he is happy at Barcelona|
|Wilshere: Arsenal play me out of position|
|Ryan backs former coach Neville|
|Keane talks up Galaxy move for Ronaldo|
|´Free agent´ Diarra wants Mourinho reunion|
|Eintracht Frankfurt beat Nuremberg to secure Bundesliga status|
|Manchester United to turn to Mourinho, the man who most resembles Ferguson|
|Manchester United kids are Van Gaal´s legacy - Ferdinand|
|´Sex-masochism´, ´fat man´ and ´Mr Mike Smalling´ - Van Gaal´s best quotes as Manchester United mana|
|I have fulfilled a long-held ambition - ´Very disappointed´ Van Gaal´s statement in full|
|Van Gaal should call time on career after Manchester United sacking|
|Better than Busby? - The stats behind Van Gaal´s United exit|
|Van Gaal sacked by Manchester United|
|Suarez expected to miss Copa America group stage|
|Herrera wants more trophies with Manchester United|
|FIFA sacks deputy secretary general Kattner|
|Asensio wants to fight for his chance at Real Madrid|
|SFA to investigate Rangers-Hibernian disorder|
|Van der Wiel takes aim at Blanc after PSG exit|
|Halilovic: Missing Euro 2016 would not be a tragedy|
|Van Gaal leaves United training ground as Mourinho speculation goes on|
|Zanetti rules out Inter move for Simeone|
|Rodgers adamant Celtic is not a step down|
|Sanches chose Bayern Munich over Manchester United|
|Rosicky was the perfect player for Arsenal - Wenger|
|Tonelli becomes Napoli´s first close-season signing|
|Thigh injury rules Steffen out of Euro 2016|
|Gotze is a perfect fit for Liverpool - Hitzfeld|
|Hummels completes Bayern move after passing medical|
|Guardiola era has been sensational - Neuer|
|Bayern will never sign a Messi or Ronaldo - Hitzfeld|
|Wilkins backs Mourinho appointment|
|Suarez´s Copa America hopes alive despite hamstring injury|
|Delneri exits Verona following relegation|
|Ireland´s Wilson ruled out of Euro 2016|
|Gotze looking forward to new season with Bayern|
|Pirlo, Giovinco out of Italy Euro 2016 squad|
|Coleman signs new Wales contract|
|Gotze talk intensifies as Bayern Munich forward leaves agent|
|Rami called up by France following Varane injury|
|United States v Ecuador: Klinsmann pins hopes on Yedlin as Copa preparations continue|
|Gabriel, Lucas Lima unsure on Santos futures|
|AC Milan to terminate Mihajlovic deal in June|
|Emery confirms Banega will leave Sevilla|
|Neville still unsure over Valencia future|
|Van Gaal arrives at United training ground amid Mourinho talk|
|Messi: We suffered but we won together|
|Evra confirms two-year Juventus deal|
|Son unfazed by Tottenham exit rumours|
|Argentine footballer dead after being struck in head|
|Arnautovic refuses to commit to Stoke|
|Sirigu: PSG wanted me out|
|MLS Review: Galaxy held by Earthquakes, Timbers end skid|
|Alba: Messi deserves credit for my goal|
|Pique: Barca deserved Copa del Rey title|
|Smalling admits relief after Lingard winner|
|Suarez, Barca unsure on extent of injury|
|Luis Enrique revels in Barca´s spectacular end to season|
|Emery proud in Copa del Rey defeat|
|Rooney hopes FA Cup lifts United - with or without Van Gaal|
|Iniesta: Copa del Rey win caps magnificent season|
|Barcelona 2 Sevilla 0 (AET): Alba and Neymar decide heated Copa del Rey final|