Leyton Orient face a tough test to reverse their woeful recent League One form when they travel to Preston North End on Saturday.
A 2-1 win at Crewe Alexandra on January 18 took Russell Slade's side top of the table, but defeats from each of their last three games have seen Orient's top-two credentials come into question.
Orient head to Deepdale with a one-place and five-point lead over their opponents, although fourth-placed Preston still have the luxury of a game in hand.
A single Joe Garner goal was enough to give the Lancashire side victory in the reverse fixture at Brisbane Road in November, and a win this time around would seal a first league double over the London club since 1996.
League leaders Brentford return to action - having not played since February 1 - with a trip to struggling Crewe.
Mark Warburton's side have not tasted defeat in 18 league outings and sit two points clear of nearest rivals Wolves, who take on relegation-threatened Notts County.
Elsewhere at the top, fifth-placed Rotherham United will look for a fifth win in six games when they take on bottom-of-the-table Stevenage.
A late Britt Assombalonga header was enough to secure a 2-1 win for sixth-placed Peterborough United away to Leyton Orient last week, a result that kept his side's push for the play-offs on track.
The 21-year old has netted 16 league goals so far this season, including five in his last four appearances, and will undoubtedly worry Walsall boss Dean Smith, who will demand a reaction from his men when they travel to London Road on Friday.
Walsall were thumped 3-0 at home to MK Dons last weekend, their first defeat since Boxing Day, leaving them two points adrift of their opponents in seventh place.
Friday's other match sees Swindon Town, who have play-off aspirations of their own, entertain Colchester United.
At the other end, Shrewsbury Town will attempt to halt a rotten run of five defeats in their last six when they host Port Vale in Saturday's early kick-off.
Much has been made in the national media of Bristol City's decision to support safe standing this week, but Steve Cotterill's men are still looking nervously over their shoulder when it comes to matters on the pitch, despite a vital win over Leyton Orient in midweek.
They face fellow strugglers Tranmere Rovers at Ashton Gate, with both teams sitting just one point off the relegation zone, level on points with Crawley Town, who host Carlisle United.
Elsewhere Coventry City entertain Bradford City, while Oldham Athletic travel to MK Dons.
|14||J. Garner||45' 64'|
|Coach: S. Grayson|
for K. Keane 57'
for C. Davies 76'
for P. Gallagher 76'
|Santos: Group-stage performances behind Portugal|
|Cacic: We cannot let Ronaldo show his strength|
|O´Neill hopes to blow Bale off course|
|Coleman impressed with Ramsey´s discipline|
|O´Neill fires derby passions ahead of Wales showdown|
|Coleman: Take emotion out of Northern Ireland clash|
|LFP sanctions six Nice players for flouting gambling rules|
|Hungary v Belgium: Lukaku targets last-four spot|
|Dyke hopes Brexit can help England youngsters|
|No favourites against Italy, says Koke|
|Krychowiak not thinking about PSG as Poland stand by Lewandowski|
|World Cup qualifying: Algeria, Cameroon and Nigeria drawn in same group|
|Brexit may damage Premier League´s pursuit of young European players|
|Germany v Slovakia: Weiss confident of repeat Augsburg success|
|France v Republic of Ireland: Long not on Henry revenge mission|
|Chelsea midfielder Baker extends Vitesse loan|
|Chiellini concerned over Brexit ´domino effect´|
|Staying in Euro 2016 gets Coleman´s vote|
|Nainggolan has a room with a balcony so he can smoke - Wilmots|
|Petkovic attempts Poland mind games|
|Wilmots would rather play Spain than Hungary|
|Morata deserves more than being a Madrid bargaining chip - Chiellini|
|AZ want record fee for Janssen|
|What does Brexit mean for European football?|
|I´m not tired, I feel sharp - Kane hits back at critics|
|Delighted Kiyotake hopes to prove his value|
|Premier League confident Brexit will not diminish its success|
|Neuer wary of Hamsik´s long-range shots|
|Genesio: Lyon do not have to sell|
|Morata thanks Juventus fans after Real Madrid return|
|Lapadula undergoes AC Milan medical|
|Santos: Not everything revolves around Ronaldo|
|Icelandic chihuahua prepares to chase the England rhino|
|Jakupovic signs new Hull City contract|
|Lagerback: Brexit will not affect England team|
|ES Setif disqualified from CAF Champions League|
|Gerland sees Kimmich as Lahm´s long-term successor|
|Navas ´recovering nicely´ from heel injury|
|Messi excited by future Barcelona challenges|
|Conte´s Italy like Atletico and Barcelona, says Xavi|
|Zidane the man to take Madrid forward, says Baptista|
|United States v Colombia: Hosts out to end Copa America on a high|
|Aubameyang: It´s my dream to play in Spain|
|Wenger not interested in France job|
|Ronaldo: Euro 2016 surprises end now for Portugal|
|Coke hopeful Sampaoli can exceed Emery at Sevilla|
|Maradona: Portugal too dependent on Ronaldo|
|´What a disaster´ - Messi takes aim at AFA|
|Guidetti: Nolito will thrive at City|
|Wanyama thanks Southampton fans following Spurs switch|
|Kranjcar: Rangers can push Celtic all the way|
|Euro 2016 Diary: Icelandic heaven and Rooney not feeling the love|
|Wenger respects Vardy, talks up Kante|
|Rooney wants to end ´disappointing´ tournament record for England|
|Di Maria in serious doubt for Copa America final|
|´We gave it all´, Alaba tells Austria fans|
|Euro 2016 Social Round-Up: Last 16 sides prepare for the knockout rounds|
|Osorio to stay on as Mexico manager despite Copa humbling|
|Tottenham complete Wanyama signing|
|Claridge: England are misusing Jamie Vardy|
|Marseille complete double swoop|
|Wales v Northern Ireland: Evans eager to prolong Irish dream|
|Underdog heroics justify UEFA´s bulkier Euros|
|Atletico Madrid president confirms Vrsaljko move|
|Rejecting Arsenal a ´mature´ move for Leicester star Vardy - Claridge|
|Switzerland v Poland: Seferovic targets final, Pazdan staying humble|
|Juanfran: Spain can use Atletico´s philosophy|
|´It’s always nice to finish above the English´ - Bale sticks the boot in again|
|Euro 2016´s top five moments so far: Payet cries a river as newcomers steal the show|
|Galatasaray fail in CAS appeal|
|´Nice will forever be in my heart´ - How France legend Just Fontaine kickstarted his career on the C|
|Team of the Euro 2016 group stage: Payet, Perisic join blistering Bale|
|The flop XI of the Euro 2016 group stage: Kane and Ibrahimovic join limp Lewandowski|
|O´Neill delighted with Northern Ireland draw placing|
|Germany optimistic on Boateng fitness|
|Croatia v Portugal: Cacic determined to spring another shock|
|Icelandic strongman Magnusson mocks Portugal´s Ronaldo|
|Noble expects West Ham stay for Payet|
|Petrov joins Villa for pre-season camp|
|´We always score our penalties´ - Hallgrimsson sends warning to England|
|Kalinic expects Croatia to progress|
|Rooney respect for Hodgson´s Slovakia gamble|
|Vardy stays at Leicester: Champions buoyed, but what next for Arsenal?|
|Lafferty backs Northern Ireland to go all the way|
|Elmohamady extends Hull stay|
|Hodgson demands ruthlessness from England to open up Iceland|
|´He was nearly dead six years ago´ - Coleman full of admiration for Duffy|
|Rangers seal Kranjcar deal|
|Iniesta wary of ´powerful´ Italy|
|I wanted to rest Gera - Storck|
|Gera living late career dream after waking from injury nightmare|
|Vardy to stay at Leicester after agreeing new contract|
|Morata still wanted by ´top Premier League clubs´|
|Sigurdsson warns Iceland of danger posed by golf buddy Kane|
|Pekerman furious with referee after Colombia´s Copa exit|
|Euro 2016 is wide open, says Cahill|
|Pizzi hails Chile´s ´winners´ mentality|
|Bjarnason hails team spirit among Iceland friends|
|Coentrao defends Ronaldo: ´Speak now, parrots!´|
|MLS Review: Alberg hat-trick inspires Union, RSL leave it late|
|Conte: I´m not from the moon, I know Spain are good|
|Santos wants more from Ronaldo|
|Colombia 0 Chile 2: Early goals see defending champions into Copa final|
|Martino receives Di Maria boost ahead of Copa final|
|De Gea thanks his critics for motivating him|
|Barca not contemplating Neymar exit|
|Pain before pleasure for Sigurdsson and Iceland´s heroes|
|Lavezzi remains upbeat despite Copa-ending injury|
|Smell of injustice: Swedish player cops farting red|
|Ibrahimovic ´very proud´ of Sweden career|
|Euro 2016 Diary: Germany grab the sunloungers, Benzema on the beach and life through a lens|
|´If you don´t know nothing, keep quiet´ - Deeney responds to speculation|
|Wilmots: Belgium must be more clinical|
|Vote remain and we´ll forgive you for 1966! - German newspaper wade into Brexit debate|
|Hamren: Sweden will never find another Ibrahimovic|
|Conte: Ireland got more than they deserved|
|O´Neill hails Ireland heroes|
|Hazard: Ibrahimovic not done yet|