Gonzalo Higuain scored twice to give Napoli their first win in four Serie A games as Milan were beaten 3-1 at Stadio San Paolo.
Adel Taarabt's debut goal had given Clarence Seedorf's Milan an early lead on Saturday, but Napoli were not to be denied a deserved victory.
Gokhan Inler equalised soon after, and Higuain struck twice after half-time to take his Serie A goal tally to 12 for the season and give Rafael Benitez's men their first league win since a 3-0 triumph at Verona on January 12.
Napoli, who were beaten by Atalanta in Serie A last weekend and Roma in semi-final of the Coppa Italia in midweek, dominated from start to finish and are now only three points behind second-placed Roma - who have two games in hand.
Defeat for Milan was their first in the league since Seedorf took over as coach last month, but the Dutchman may count his blessings that his side were not beaten by a more handsome margin.
Napoli defender Faouzi Ghoulam replaced the injured Anthony Reveillere and Dries Mertens came in for Jose Callejon, who started on the bench along with January signing Henrique.
Michael Essien and Taarabt made their Milan debuts, while striker Mario Balotelli returned from suspension as Seedorf made six changes to the side that drew with Torino last weekend.
Napoli made a bright start, but they were caught out after only seven minutes when QPR loanee Taarabt raced forward before placing a measured right-foot strike into the far corner of the net from just outside the area as the home defence backed off.
The goal was harsh on Benitez's team, but they were level three minutes later courtesy of a fine left-foot strike from Inler that took a deflection and looped over Christian Abbiati.
Milan struggled to cope with Napoli's attacking threat, and Higuain was inches away from putting the home side in front when his shot flashed wide of the far post.
Abbiati was lucky to escape with only a yellow card after 22 minutes when he rushed out of his area and upended Mertens after the winger had raced onto a through ball and attempted to lob the veteran goalkeeper.
To add insult to injury, Abbiati kept out the resulting free-kick from the Belgium international, before Marek Hamsik's venomous left-foot volley flashed just wide.
Christian Maggio then hit the post from a tight angle and Lorenzo Insigne headed just wide as Milan somehow went in level at the break.
Kaka replaced fellow Brazilian Robinho at half-time, but his introduction failed to turn the tide as Napoli maintained the upper hand and Abbiati could only watch on as Insigne's strike flashed wide.
It was only a matter of time before the home side took the lead, and it was former Real Madrid man Higuain who put them in front when he headed home an inviting cross from Inler 11 minutes into the second half.
The Argentina striker was a constant menace and he ought to have given Napoli breathing space but missed his kick after evading the vulnerable Philippe Mexes.
Napoli could have been made to pay for not making their dominance count but Taarabt's strike was kept out by Pepe Reina and then Balotelli failed to capitalise after the Spanish goalkeeper had totally missed his kick.
Higuain sealed the points with eight minutes left, though, slotting home from close range after Callejon picked him out.
|88||G. İnler||11' 38'|
|9||G. Higuaín||56' 82'|
|Coach: Rafael Benítez|
for L. Insigne 78'
for M. Hamšík 83'
for G. İnler 89'
|Coyle leaves Houston Dynamo|
|McLaren could end Mercedes dominance - Alonso|
|Orlando City 2 Philadelphia Union 2: Tribbett rescues point in controversial contest|
|United States 1 Ecuador 0: Last-gasp Nagbe goal lifts hosts in Copa America warm-up|
|Djourou compares Xhaka to Pirlo|
|Gallas ´very proud´ of former boss Ranieri´s title glory|
|Copa America to use goal-line technology|
|Smith likens Postecoglou to Klopp|
|Hart backs Sterling to shine at Euro 2016|
|Giovinco happy in MLS despite Euro 2016 snub|
|Balotelli set for Liverpool return, confirms Berlusconi|
|Atletico must win Champions League - Cerezo|
|Arbeloa: Mourinho didn´t get enough recognition at Madrid|
|Mijatovic: Bale can save Madrid´s season in Champions League final|
|Gallas expects Conte to revive Chelsea|
|Deschamps ´annoyed, but not worried´ by Varane´s absence|
|´Impossible´ to see MSN leaving Barcelona - Bartomeu|
|Thiago pledges future to Bayern|
|AFC Champions League Review: Urawa pay the penalty as Seoul advance|
|Uruguay v Trinidad and Tobago: Sanchez skips final to help Suarez-less La Celeste|
|Benitez ´convinced´ he can win trophies at Newcastle|
|Nigeria v Mali: Moses among many absentees for Super Eagles|
|Benitez to stay at Newcastle|
|Kramaric leaves Leicester for Hoffenheim permanently|
|Neustadter gets green light for Russia Euro 2016 selection|
|Chile v Jamaica: Copa plans crystallize in Vina del Mar|
|Ledley making progress in bid to prove Euro 2016 fitness|
|Gotze returns to Germany training|
|Ronaldo: Madrid would be smart to give me a new deal|
|Varane disappointed by Euros absence|
|Republic of Ireland v Netherlands: O´Neill wants confident display|
|Ronaldo shakes off injury in Real Madrid training|
|Atletico star Griezmann ´listening to different clubs´|
|United States - Ecuador Preview: Klinsmann pins hopes on Yedlin as Copa preparations continue|
|Gold tells Middlesbrough to ´dream on´ over Antonio|
|Schweinsteiger wants Mourinho to spice up Manchester derby|
|England v Australia: All eyes on Rashford debut|
|Aggressive Premier League better for me - Xhaka|
|Schweinsteiger ´right on schedule´ for Euro 2016|
|Darmian relishing Euros after return from injury|
|Northern Ireland v Belarus: Last chance to impress as O´Neill prepares to trim squad|
|Ventura leaves Torino amid Italy talk, Mihajlovic appointed|
|Sevilla confident of keeping Emery|
|Godin wants Atletico to use 2014 defeat as inspiration|
|Xhaka agrees Arsenal move|
|Idolisation of Ibrahimovic warranted Sweden captaincy - Hamren|
|Scholes hopes Mourinho keeps Giggs at Manchester United|
|Gotze snubbing Liverpool will boost Germany - Bierhoff|
|Bosz honoured by Ajax appointment|
|Ramos highlights Griezmann threat|
|Record-chasing Ronaldo and taming the Wolves - Real Madrid´s route to the Champions League final|
|Donnarumma dreams of being Milan captain|
|Koke: History, not revenge motivating Atletico|
|Costa Rica v Venezuela: Hosts ramp up preparations for maiden Copa America tilt|
|Argentina v Honduras: Messi and co warm up for Copa America|
|USA will win a World Cup, says Donovan|
|Pumas UNAM 2 Independiente del Valle 1 (3-3 agg, 3-5 on penalties): Hosts suffer shoot-out heartbrea|
|Gracia leaves Malaga as Rubin Kazan loom|
|Messi: Argentina deserve to be Copa America champions|
|Dybala included in Argentina´s preliminary Olympics squad|
|Mourinho and United a ´good wedding´ - Ancelotti|
|Klinsmann: Copa America better than Euros|
|Messi: Joining Barcelona not an easy decision|
|Carrico receives four-game ban for homophobic slur|
|Dani Alves wants Atletico to win Champions League|
|McNair out to impress ´world-class´ Mourinho|
|Ranieri: Premier League survival is Leicester´s priority next season|
|Argentina forward Lavezzi suffers hamstring scare|
|Koeman talks ´very positive´, say Southampton|
|Rami replaces injured Varane in France´s Euro 2016 squad|
|Matthaus applauds Gotze for rejecting ´easy solution´ of Liverpool|
|Suarez silenced his doubters - De Boer|
|AFC Champions League Review: Jeonbuk, Shanghai SIPG progress|
|Klopp can take Liverpool right to the top, says McAllister|
|Lindelof happy at Benfica amid Real Madrid, Barcelona links|
|Zidane is perfect on and off the pitch - Lippi|
|Bale: Zidane has brought the best out of Real Madrid|
|Favre takes over as Puel and Nice part ways|
|Liverpool complete Karius deal|
|Van Gaal was treated poorly by United, but Mourinho will be a success - De Boer|
|Dani Alves: I have won more titles than Pele|
|I know who I´m taking - Conte sure on Euro 2016 selection|
|Xavi backs Guardiola to ´change the face of English football´|
|Lucescu appointed Zenit boss|
|Manchester United and Liverpool hit with €40,000 fines|
|Weinzierl: I have nothing to lose at Schalke|
|Rangers complete Barton signing|
|Italy better placed as underdogs ahead of Euro´s - Motta|
|Cantona: I love Mourinho, but he is not Manchester United|
|Ben Arfa wants Lyon move - Aulas|
|David Silva praises Iniesta´s Copa del Rey heroics|
|´It was a little scare´ - Ronaldo plays down injury fears|
|Eder the real deal for Lille|
|Van Gaal treated unfairly during Manchester United spell - Daley Blind|
|Ginola doing ´very well´ after heart surgery|
|Depay rules out Manchester United exit following Van Gaal departure|
|Hojbjerg confirms desire to leave Bayern|
|Ronaldo leaves Madrid training early after knock|
|Abbiati unimpressed with Milan players´ attitude|
|Pepe calls on Madrid to continue making history|
|Ayestaran signs two-year deal with Valencia|
|Montolivo, Antonelli sign new AC Milan contracts|
|Ronaldo ready for UCL final after being rested from practice match|
|Hummels, Sanches deals will not stop Bayern spending - Rummenigge|
|Oblak´s penalty heroics, Griezmann´s Barcelona brace - Atletico Madrid´s route to the Champions Leag|
|Salvio all but confirms Gaitan will join Atletico Madrid|
|Motta warns PSG over Ronaldo, Neymar interest|
|Europa League Mourinho´s best hope for United trophy - Sheringham|
|Injustice if Iniesta never wins a Ballon d´Or - Del Bosque|
|Van Gaal didn´t deserve United sacking - Blind|
|I´ll be happy if we make Euro 2016 semi-finals - Del Bosque|
|Koke: Why would I want to leave Atletico?|
|Fofana could retire aged 25 - Lyon president|
|Sandro set to leave Barcelona|
|Silva plays down injury worries ahead of Euro 2016|
|United would be brave to appoint Mourinho, says Schmeichel|
|Neymar adamant he is happy at Barcelona|
|Wilshere: Arsenal play me out of position|
|Ryan backs former coach Neville|
|Keane talks up Galaxy move for Ronaldo|
|´Free agent´ Diarra wants Mourinho reunion|