Mario Mandzukic inspired Bayern Munich to victory at Nuremberg, while Borussia Dortmund and Eintracht Frankfurt enjoyed big wins.
Defending champions Bayern restored their 13-point lead at the Bundesliga summit thanks to a 2-0 derby success over to make it 12 successive league victory.
Toni Kroos, who recently rejected a contract extension, was left out by coach Pep Guardiola and Josip Drmic almost gave Nuremberg the lead early on, but Mandzukic opened the scoring on 18 minutes with an improvised finish. It was the 27-year-old striker's 12th league goal of the season.
Mandzukic then set up the second for Philipp Lahm, whose shot went through the grasp of Raphael Schafer for his first Bundesliga goal since 2010.
Dortmund moved four points behind second-placed Bayer Leverkusen by thrashing Werder Bremen 5-1 on their travels.
Robert Lewandowski broke the deadlock to end his personal goal drought in the league on 475 minutes, while Manuel Friedrich and a Henrikh Mkhitaryan double put Jurgen Klopp’s side well in command. Lewandowski's second sent him top of the Bundesliga scoring chart before substitute Levent Aycicek grabbed a consolation for Bremen.
Wolfsburg beat Mainz 3-0 to move level on points with fifth-placed Borussia Monchengladbach.
A penalty from Swiss full-back Ricardo Rodriguez put Dieter Hecking's men ahead, with Brazil midfielder Luiz Gustavo and Dutch striker Bas Dost also on target. Rodriguez has now scored four goals in his last nine league appearances.
Eintracht Frankfurt cruised to a 3-0 win over rock-bottom Eintracht Braunschweig to stride four points clear of the relegation zone and leave their visitors six points adrift of safety. Johannes Flum, Alexander Meier and Stefan Aigner got Frankfurt’s goals.
Freiburg and Hoffenheim played out a 1-1 draw in a battle of sides in the bottom half. Jonathan Schmid’s 68th-mniute goal looked to have done enough for Freiburg, but substitute Anthony Modeste got a late equaliser. The point was nevertheless enough for Freiburg to escape the relegation zone.
Elsewhere, Hamburg's dreadful run continued following a 3-0 defeat at home to Hertha Berlin, their sixth successive Bundesliga loss.
The visitors should have been in front after 15 minutes when Adrian Ramos saw his penalty saved by Rene Adler, but it mattered little as Hertha raced into a three-goal lead before the break.
Sami Allagui put Hertha ahead shortly after the penalty miss before Ramos atoned for his error by scoring in the 23rd and 38th minutes to consign Hamburg to another miserable defeat, one which leaves them in the bottom two.
|Coach: G. Verbeek|
for T. Chandler 10'
for D. Ginczek 22'
for A. Hloušek 76'
|Bartomeu: Deal in place for Turan|
|Parejo re-signs with Valencia|
|MLS Review: Sounders return to winning ways|
|Klinsmann unhappy with USA performance|
|High hopes for Paraguay - Diaz|
|Gareca: More to come from Peru|
|Gerrard had European offers|
|Argentina out to spoil Chile´s party - Martino|
|Sampaoli: Chile won´t change style|
|Di Maria will come good at United - Rojo|
|Peru 2 Paraguay 0: Gareca´s men finish third at Copa|
|United States 4 Guatemala 0: Klinsmann´s men win comfortably|
|´I’d prefer no-one to know my name´ - Bassett|
|Matthews completes Sunderland move|
|Podolski set for Galatasaray medical|
|Gundogan inspires Dortmund victory|
|Inter confirm Montoya capture|
|Murillo joins Inter, as Kuzmanovic and Obi depart|
|Falcao signing not a risk, says former Chelsea star|
|Deeney agrees new Watford deal|
|Confidence and service the key to Falcao success at Chelsea|
|No bids for ´Chelsea target´ Baba, claim Augsburg|
|Derby swoop for Ince|
|Fiorentina consider legal action over Salah ´no-show´|
|Chelsea the team to beat in the Premier League, says Neville|
|Storari exits Juve for Cagliari|
|UEFA removes FFP restrictions on Man City and PSG|
|West Brom hope for new owners within the month|
|Chelsea agree loan deal for Falcao|
|Kuyt eyes trophies on Feyenoord return|
|Chile v Argentina: History beckons ahead of Copa America final|
|Wallace extends Monaco loan|
|Mihajlovic wants to instill fear factor at Milan|
|Mignolet improving at Liverpool - Grobbelaar|
|Mumbai City name Anelka player-manager|
|Olivia the parrot predicts Japan to win Women´s World Cup|
|Lusitans coach blasts Bilic´s ´lack of respect´|
|Sakho eyes more Europa League wins|
|Gareca wants Peru to keep building|
|Chile ´no chance´ if Argentina produce their best - Diaz|
|Ocampos joins Marseille permanently|
|Europa League Review: Cloud-nine Brondby ignite opening round|
|West Ham 3 Lusitans 0: Sakho nets twice at start of Europa League journey|
|Holebas makes Watford move|
|Milan secure Adriano signing|
|Peru v Paraguay: Diaz counts cost of semi-final loss|
|Bastia hit out at reports of extra debt|
|Hernandez has successful surgery|
|Odemwingie signs one-year Stoke extension|
|Uth signs for Hoffenheim|
|Henen seals Everton return|
|Cattermole pens long-term Sunderland deal|
|United States v Guatemala: Klinsmann backs Dempsey ahead of Gold Cup warm-up|
|West Ham working on Jenkinson return - Gold|
|Milan agree deal for Bacca|
|Real buy back Vazquez from Espanyol|
|Richards leaves Swansea for Fulham|
|McShane signs for Reading|
|Giggs tells youngsters to seize US chance|
|Hammond pens Leicester extension|
|Only Schweinsteiger can decide Bayern future - Guardiola|
|Cech plans to play until he´s 40|
|Montoya arrives in Milan ahead of Inter move|
|Hernandez out of Gold Cup|
|US asks Switzerland to extradite seven FIFA officials|
|MLS Preview: Sounders seek momentum switch|
|Mexico 0 Honduras 0: Hernandez injury sours friendly|
|Hernandez taken to hospital|
|Garay in doubt for Copa America final|
|Wambach: USA peaking for World Cup final|
|Bassett ´an absolute hero´ despite own goal - Sampson|
|Japan 2 England 1: Late own goal breaks English hearts|
|Salvo quits as Valencia president|
|Costa not Ribery cover - Bayern director Sammer|