Cristiano Ronaldo was sent off as Real Madrid lost ground on league leaders Atletico Madrid by drawing 1-1 with Athletic Bilbao.
The Portuguese forward saw red after clashing with Ander Iturraspe and appearing to push the defender in the face.
Real had moved ahead in the 65th minute when Ronaldo set up Jese to score from close range on his first La Liga start.
Bilbao equalised through Ibai Gomez after 73 minutes, the substitute finding the net with his first touch, and two minutes later Real were down to 10 men courtesy of Ronaldo's dismissal.
The result ends a run of five consecutive league wins for Carlo Ancelotti's men and leaves them three points behind Atletico, and level with Barcelona after the latter's defeat to Valencia.
Bilbao maintain their undefeated league record at the new San Mames, and have not lost in four league games.
Real Madrid's intentions were clear from the outset and they started at a ferocious pace with Ronaldo and Jese both firing wide within the first three minutes.
However, Bilbao soon settled and should have gone in front in the 18th minute when Ander Herrera's superb throughball found Aritz Aduriz. After escaping the attentions of Pepe, he could only place wide of Diego Lopez's right-hand post.
Another good chance was spurned by the hosts when Iker Muniain failed to control Oscar de Marcos' fine low cross.
Real were subdued but set out to change that straight away in the second half, Luka Modric unleashing a long-range drive that Gorka Iraizoz did well to tip around the post.
The visitors thought they had taken the lead in the 50th minute when Xabi Alonso's lofted pass was volleyed in by Ronaldo, but the scorer had strayed marginally offside.
Bilbao were indebted to Iraizoz again three minutes later as he repelled Karim Benzema's fierce near-post drive, while Muniain unleashed a curling effort at the other end that went just over.
Real hit the front in the 65th minute when Ronaldo's low cross found the sliding Jese, who prodded in.
The lead did not last long, as Ibai came on with 16 minutes left and almost immediately drilled in a fine 25-yard effort that went in off the post.
Real were then reduced to 10 men when Ronaldo and Iturraspe clashed and the forward was penalised for raising his hands.
It could have been worse for Real, but Diego Lopez made a superb flying save to tip over Ibai's dipping shot.
|Atletico announce Velazquez capture|
|Giroud set for lengthy absence - Wenger|
|Holders City handed home clash with Wednesday|
|La Liga Preview: Saul not worried by Simeone absence, Barca face tough Villarreal test|
|Eto´o retires from Cameroon duty|
|Aston Villa 0 Leyton Orient 1: Late Vincelot winner sends underdogs through|
|Birmingham City 0 Sunderland 3: Late strikes stun hosts|
|Arsenal 1 Besiktas 0 (1-0 agg): Alexis strike takes Wenger´s men through|
|Stoke City 3 Portsmouth 0: Walters brace sees hosts into League Cup third round|
|Burton Albion 1 QPR 0: Late strike seals upset for fourth-tier hosts|
|Ligue 1 Preview: Bordeaux look to maintain 100 per cent start|
|Dunga: No one guaranteed a place in Brazil squad|
|Serie A Preview: Juve´s Allegri era starts at Chievo|
|Mazzarri calls for professional Inter|
|Utrecht swoop for Peterson|
|Deeney extends Watford stay|
|Alonso calls time on international career|
|Bundesliga Preview: Schalke captain Howedes issues rallying cry, Leverkusen face Hertha|
|Fazio joins Spurs from Sevilla|
|Warnock will control transfers - Parish|
|Pochettino wants Soldado and Townsend to stay at Spurs|
|Augsburg v Borussia Dortmund: Weidenfeller returns for wobbling visitors|
|Celtic complete Wakaso deal|
|Seoul 0 Pohang Steelers 0 (aet, 3-0 on penalties): Yu heroics send Seoul through|
|Guangzhou Evergrande 2 Western Sydney Wanderers 1: Wanderers squeeze through on away goals|
|I´m the future, Benatia´s the past - Manolas|
|Osotspa 3 Chiangrai United 3: Visitors secure point with late rally|
|Israel versus Belgium fixture postponed|
|Fernandes reveals Redknapp contract talks|
|Warnock makes Palace return|
|Eto´o grateful to Mourinho|
|Maiga loaned to Metz|
|Pearson rues ´poor´ Leicester display|
|Bruce: Rhodes deal dead and buried|
|Balotelli set to face Tottenham|
|Di Maria wanted Real stay|
|Dyche wary of inflated transfer market|
|Celtic didn´t deserve Champions League, concedes Deila|
|Game of two halves for Koeman|
|Allardyce hails ´inspired´ Howard|
|CONCACAF Champions League Review: Red Bulls up and running, Rodriguez stars for Saprissa|
|Copa Sudamericana Review: Gimenez double helps Emelec through|
|Eredivisie Preview: Guardado set for PSV bow, Ajax eye recovery|
|Van Gaal ´not shocked´ by Dons defeat|
|Deila: Celtic deserved Champions League exit|
|Barca agree deal for Pereira|
|Lopetegui lauds Porto progression|
|League Cup Review: United hammered by MK Dons, West Ham lose on penalties|
|West Brom 1 Oxford United 1 (aet, 7-6 on penalties): Hosts avoid cup shock|
|Manchester United win ´something dreams are made of´ - Robinson|
|UEFA Champions League Review: Celtic out again, Porto safely through|
|United rebuild will take time - Van Gaal|
|Erbil 2 Ha Noi T&T 0 (agg 3-0): Iraqi side comfortably into the AFC Cup semis|
|West Ham 1 Sheffield United 1 (aet, 4-5 on penalties): Valencia miss proves crucial in shootout defe|
|Millwall 0 Southampton 2: Koeman claims first win|
|MK Dons 4 Manchester United 0: Humiliation for Van Gaal|
|Swansea City 1 Rotherham United 0: Gomis off the mark in League Cup clash|
|Leicester City 0 Shrewsbury Town 1: Mangan seals shock win for Shrewsbury|
|Burnley 0 Sheffield Wednesday 1: Visitors dump Dyche´s men out of League Cup|
|Walsall 0 Crystal Palace 3: Gayle treble lifts Palace gloom|
|Gillingham 0 Newcastle United 1: Egan own goal secures Newcastle triumph|
|Coupe de la Ligue Review: Auxerre, Ajaccio secure big wins|
|Al Ittihad 1 Al Ain 3: Gyan helps visitors secure semi-final spot|
|Hull City v Lokeren: Elmohamady calls for vocal support|
|Al Sadd 0 Al Hilal 0 (agg 0-1): Visitors hang on to progress|
|Tottenham v AEL: Pochettino eyes continuation of good form|
|Benitez: The pressure is on Athletic|
|Eto´o completes Goodison Park move|
|Reus nets in Dortmund friendly win|
|Roma secure Manolas signing|
|Aduriz: We can´t play for a draw|
|Al Hadd 2 Al Qadsia 2 (agg 3-3): Last-gasp leveller seals away-goal victory for visitors|
|United break transfer record for Di Maria|
|Hull announce Dawson signing|
|Moses set for Stoke debut|
|Hodgson pays tribute to Lampard|
|UEFA Europa League Play-Off Preview: Lyon look to reverse upset, Inter defend three-goal lead|
|Lukimya pens new Bremen deal|
|Bayern complete Benatia swoop|
|Bayern complete Benatia swoop|
|M´Bia replaces Eto´o as Cameroon captain|
|Palermo complete double defensive deal|
|Bakambu claims Swansea and Freiburg interest|
|Inter v Stjarnan: Mazzarri may tinker for Europa League test|
|Kitchee 0 Ninh Binh 1 (agg 4-3): Hosts hold off strong challenge to reach last four|
|Guardado pens PSV loan deal|
|Lampard announces international retirement|
|Wenger unsure on severity of Giroud injury|
|Mascherano signs new Barca contract|
|Basanta seized Europe chance with Fiorentina|
|Marchisio: Allegri´s philosophy will boost Juve´s Europe hopes|
|Persipura 6 Al Kuwait 1 (agg 8-4): Hosts romp holders to make history|
|Cahill thrilled with Chelsea start|
|Gardner completes Brighton loan|
|Pienaar out of Chelsea clash, Lukaku faces assessment|
|Seoul v Pohang Steelers: Korean rivals battle for AFC Champions League semi spot|
|Lamela keen to add goals|
|Jovetic refuses to take plaudits|
|Henderson tips Balotelli for success|
|Moya takes positives from defensive showing|
|Pepe unperturbed by scrappy showing|
|New youngsters will adapt, says Rodgers|
|Girard confident of Lille progression|
|Riise fears for Fulham under Magath|
|Balotelli: ´It was a mistake´ to leave England|
|Simeone: My suspension made no difference|
|Guangzhou Evergrande v Western Sydney Wanderers: Aussies braced for hostile reception|
|Bayern need time - Alaba|
|Ancelotti: Fatigue behind lacklustre display|
|Pellegrini delighted with Premier League start|
|Moreirense 0 Sporting Braga 0: Conceicao´s men held in Moreira|
|Liverpool will bounce back - Rodgers|