Oribe Peralta struck an injury-time winner as America prevailed 3-2 over Morelia to make it five victories from five in Liga MX on Saturday.
Mexico international Peralta fired the ball beyond onrushing Morelia goalkeeper Felipe Rodriguez in the second minute of added time to preserve America's perfect start to the Apertura season at the Estadio Azteca.
An unmarked Pablo Aguilar opened the scoring for America in the 38th minute with a close-range header.
Duvier Riascos levelled proceedings seven minutes into the second half courtesy of a header that hit the post and came off Moises Munoz's leg in goal.
Scores were level for just five minutes after America's Rubens Sambueza drove into space and unleashed a powerful shot from outside the penalty area.
Slovakian substitute David Depetris poked the ball home inside the six-yard box to restore parity in the 76th minute.
However, Peralta's 93rd-minute goal - his third in as many games - earned America maximum points against their lowly opponents, who sit second-bottom.
America's run of five consecutive wins has them two points clear of Atlas atop the table.
Atlas were 1-0 victors over cellar-dwellers Universidad Guadalajara thanks to Luis Cabellero's 90th-minute penalty on Saturday.
New recruit and the league's top goalscorer Dorlan Pabon netted a hat-trick as third-placed Monterrey returned to the winners list, toppling Cruz Azul 3-1 on Saturday.
Pabon, who joined from Brazilian outfit Sao Paulo at the start of the season, completed his treble with two goals in the final 17 minutes, as Monterrey ended their two-game winless streak.
Monterrey are level on 10 points with Queretaro, who played out a goalless draw at home to Veracruz.
In other results, defending champions Leon came from behind to beat Pumas UNAM 2-1.
Pablo Velazquez scored twice as Toluca accounted for Pachuca 3-0 at the Estadio Nemesio Diez.
Paulo da Silva was also on target for the home side, who now sit fifth in the table.
Tijuana ended a run of back-to-back draws after they edged Chiapas 2-1 courtesy of Dario Benedetto's double.
Carlos Quintero struck two minutes from time as Santo Laguna upstaged Guadalajara 1-0, while Puebla and Tigres UANL drew 1-1.
|12||Pablo Aguilar||9' 38'|
|24||O. Peralta||45' 90+3'|
|Coach: A. Mohamed|
for L. Rey 61'
for M. Arroyo 79'
for O. Martínez 89'
|Sporting Kansas City 4 Dallas 0: Nemeth, Zusi destroy 10-man visitors|
|Geferson replaces Marcelo for Copa America|
|PSG captain Silva in doubt for Coupe de France final|
|Valverde: Bilbao to stick to style in Copa final|
|´Another round of indictments´ expected in FIFA case|
|Youngsters promoted to Australia´s squad to face Kyrgyzstan|
|Disappointed FFA, US Soccer still want change|
|Gutierrez: Ashley abandoned me|
|US senator urges Blatter to release Garcia Report|
|Gutierrez, Taylor released by Newcastle|
|Figo calls on re-elected Blatter to resign after ´dark day´ for football|
|Szczesny blasts father over ´idiotic´ comments|
|Blatter vows to leave ´strong´ FIFA|
|Blatter re-elected as FIFA president|
|BREAKING NEWS: FIFA elections set for second round of voting|
|Atsu wings in for Bournemouth campaign|
|Klopp: Pokal final not about me|
|Clement says Real goodbyes|
|Inter v Empoli: Icardi looking for final flourish|
|BREAKING NEWS: Blatter - I will fix FIFA|
|Northern Ireland v Qatar: O´Neill keen to prepare for Romania test|
|Palestine drop proposal for Israel suspension|
|Suarez will only get better, warns Iniesta|
|Martinez keen to recruit quickly|
|Monk keen to build on successful Swansea campaign|
|Fit-again Suarez set to aid Barca´s treble quest|
|Anonymous ´bomb´ threat received at FIFA Congress|
|Qatar organisers insist World Cup bid met ´highest ethical standards´|
|Wilkinson and Sorensen leave Stoke|
|Blatter: You can´t ask everyone to behave ethically just like that|
|Van Bronckhorst positive about Feyenoord future|
|Australian police to look into FFA-Warner dealings|
|Dardai signs Hertha deal|
|Protester interrupts FIFA Congress|
|Spurs complete Wimmer signing|
|Warner questions charges following release|
|Mexico v Guatemala: Herrera´s men kick off Copa preparations|
|New Zealand no longer supporting Blatter|
|´Post-World Cup trauma´ affected Mertesacker|
|Racing Club 0 Guarani 0 (0-1 agg): Draw sees Paraguayans through|
|Hamburg shocked by Karlsruher attack - Labbadia|
|Serie A Preview: Napoli, Lazio eye Champions League|
|Hodgson will not overstay England welcome|
|Scholes: United must keep Di Maria|
|Leyton Orient appoint Hendon|
|Benteke has a buy-out clause - Sherwood|
|US Soccer will support Prince Ali in FIFA election|
|Dynamo disappointed with officials after City friendly abandoned|
|Calls for Suarez appeal gather momentum|
|Eredvisie Review: Vitesse denied by late Uth goal, NAC Breda boost survival hopes|
|Rangers 1 Motherwell 3: McCall´s men facing uphill struggle|
|Hamburg 1 Karlsruher 1: Bundesliga side escape with draw|
|Blatter vows to lead FIFA clear of trouble as corruption scandal rolls on|
|Bundesliga: Bayern Munich season review - League crown not enough to signal successful campaign|
|Genoa forced to wait for UEFA licence|
|Injured Cardozo out of Paraguay squad|
|CONCACAF provisionally dismisses Webb and Li|
|Klopp: Career highlights of a charismatic coach|
|Verona v Juventus: Ogbonna seeks strong Champions League warm-up|
|FA charges Demetriou over betting breaches|
|Atalanta v Milan: Inzaghi faces last chance to prove worth|
|King joins Bournemouth as QPR rebuild begins|
|Plymouth part ways with Sheridan|
|Hernandez banned for three matches|
|Chelsea star Fabregas has nose surgery|
|Blatter: More bad news may follow|
|Galliani hopeful over Ancelotti deal|
|Frontzeck to continue as Hannover coach|
|Tremmel released as Tate waves goodbye to Swansea|
|Arsenal v Aston Villa: Sherwood out to upset holders|
|UEFA open to boycott of World Cup - Platini|
|Porto activate release clause for Casemiro|
|Athletic Bilbao v Barcelona: Catalans seeking second leg of treble|
|Auxerre v Paris Saint-Germain: History beckons for Ligue 1 champions|
|Cole confirms West Ham departure|
|UEFA elect not to boycott FIFA Congress|
|Borussia Dortmund v Wolfsburg: Klopp aiming for triumphant farewell|
|Flamini hails Coquelin impact at Arsenal|
|South Africa deny wrongdoing in World Cup bid|
|Benitez confirms Napoli exit|
|McShane among six released by Hull|
|Cerci committed to Milan|
|West Ham expect Collins to return for pre-season|
|Real deny Pogba bid|
|Important to keep Chelsea squad together - Mourinho|
|Alonso: Gerrard was magic|
|Pochettino silent on Ings speculation|
|Visa threatens to ´reassess´ sponsorship amid FIFA scandal|
|Blatter skips FIFA Medical Conference|
|MLS Preview: Revs not out for revenge against Galaxy|
|MLS Review: Sounders go top in West, Timbers and Galaxy win|
|AFC stands by Blatter|
|Matheus ´alright´ after collapse - Markevych|
|Copa Libertadores Review: River, Inter through to semis|
|Signing Toni a ´long shot´ for Adelaide|
|Ramsey good enough for Barca - Coleman|
|Bacuna pushing for Benteke stay|
|Evans stunner settles City friendly in Toronto|
|Banega: Emery a great coach|
|Emery tight-lipped on Sevilla future|
|Argentina finalise Copa America squad|
|Nike issues statement following arrest of FIFA officials|