Aided by a pair of high-profile arrivals, Chelsea look set to provide the greatest threat to Manchester City's Premier League title defence.
In Jose Mourinho's first spell in charge, Chelsea won back to back league titles in 2005 and 2006, but the Portuguese failed to repeat that trick on his return last season as they ended the campaign in third place, four points shy of champions City.
Mourinho spent much of the campaign bemoaning his lack of quality striking options, and Chelsea were quick to address that during the current transfer window.
In securing the services of Diego Costa, Mourinho has added a forward who netted 36 goals in all competitions for Atletico Madrid last term, while he has also conducted what appears to be a shrewd piece of business by bringing Didier Drogba back to the club.
In Costa, Chelsea will feel they have the man to fire them to glory, while the acquisition of Cesc Fabregas from Barcelona should offset the loss of Frank Lampard's goalscoring and creative threat from midfield.
It remains to be seen how Manchester United will fare under the stewardship of a second new manager in as many seasons.
Following the dominance of the Alex Ferguson era, David Moyes' appointment proved a huge disappointment to all at Old Trafford, with the Scot failing to see out the season as United finished seventh - their lowest ever Premier League placing.
Louis van Gaal, fresh from guiding the Netherlands to third place at the World Cup, has impressed in pre-season, winning the International Champions Cup with victories over the likes of Roma, Inter, Real Madrid and Liverpool.
However, in working with much the same squad as Moyes, Van Gaal will have to show all of his managerial mastery if he is to bridge the 22-point gap that separated them and neighbours City last season.
City, meanwhile, boast arguably the strongest squad in the division, with Manuel Pellegrini enjoying a plethora of attacking talent at his disposal.
Pellegrini's team held their nerve in the final weeks of last season, winning their last five matches to overtake Liverpool and claim their second crown in three years, two points ahead of the men from Anfield.
If they are to challenge as closely this time around, Liverpool must learn to cope without the inspirational Luis Suarez.
The Uruguayan has departed for Barcelona after a scintillating 2013-14, in which he scored 31 Premier League goals and struck up a lethal partnership with Daniel Sturridge.
A 2-0 defeat to Chelsea and a 3-3 draw at Crystal Palace - having led 3-0 - cost Liverpool dearly last season, and another club likely to be wistfully asking 'what if' are Arsenal, who topped the table for long periods of the campaign only to fall away in what has become a seemingly customary spring-time implosion.
Arsenal fans will have at least been appeased by the FA Cup triumph over Hull City in May, while the capture of Alexis Sanchez from Barcelona suggests Arsene Wenger's club-record signing of Mesut Ozil last year was not a one-off from a manager who is famed for his prudence in the transfer market.
Everton, who just missed out on UEFA Champions League qualification last term by finishing fifth, have smashed their transfer record for Romelu Lukaku and will hope to go one better this time around, while Mauricio Pochettino has swapped Southampton for Tottenham.
The three promoted sides see two new faces to Premier League management - and one very familiar one.
Nigel Pearson's Leicester City were comfortable Championship winners in 2013-14, while Sean Dyche's Burnley surprised many by finishing runners-up despite having one of the smallest squads in the division.
QPR, under the wily leadership of Harry Redknapp, were able to bounce back at the first available opportunity via the play-offs, while the likes of Alan Irvine at West Brom will also take to top-flight management for the first time.
Meanwhile, another new face will be seen at Southampton as Ronald Koeman attempts to perform well with a squad shorn of the likes of Adam Lallana, Rickie Lambert, Luke Shaw and Dejan Lovren.
|BREAKING NEWS: Arnautovic signs new Stoke deal|
|Smith leaves Liverpool for Bournemouth|
|Barcelona insist Arda Turan will stay|
|Andre Gomes: Barcelona suit my identity better than Real Madrid|
|Niersbach to appeal FIFA ban|
|Barcelona agree Mascherano renewal|
|Fernandinho can play in 10 positions - Guardiola|
|Reading´s kit launch is out of this world|
|Ben Arfa: I do not want to be PSG´s star player|
|FA Cup to trial fourth substitute|
|We want Balotelli and he wants us, says Besiktas chief|
|Crowd welcomes Higuain as he arrives for Juventus medical|
|Guardiola warns Man City stars: If you´re not fit, danger is coming|
|Mkhitaryan prepares to prove himself at United|
|Cavani: No pressure replacing Ibrahimovic|
|Wenger vows to keep transfer plans ´secret´ after Lacazette snub|
|Brannagan open to Championship loan move|
|Wenger wants to sign Mertesacker replacement|
|Ancelotti: Bayern´s transfer business done|
|Brisbane Roar sign former Danish international Kristensen|
|Verratti, Luiz missing for PSG|
|Sounders part ways with foundation coach Schmid|
|Mane turned down Manchester United for Liverpool|
|Zidane on Pogba: Until August 31, anything can happen|
|Mkhitaryan driven by father´s death|
|Inter rejected Napoli offer for Icardi, says president|
|Clichy: City fighting fit after Guardiola pizza ban|
|Everton and Burnley win as Hull are held|
|Ajax held by PAOK after Cillessen howler|
|Conte left frustrated by ´crazy´ money in transfer market|
|Neymar makes Barcelona case to Gabriel Jesus|
|Rostov comeback twice for Champions League draw with Anderlecht.|
|Arsenal defender Mertesacker set for lengthy lay-off|
|Conte not selling ´fantastic´ Matic|
|Ibrahimovic keen on MLS and Beckham´s Miami project|
|Neymar: I play for Messi, he´s the man|
|Barcelona reveal details of Andre Gomes deal|
|Suarez bullish over Barcelona prospects|
|Ajax claim Napoli keen on Milik to replace Higuain|
|Totti labels Higuain´s Juventus move ´a disaster´|
|Juventus confirm Higuain deal|
|Pato to Villarreal ´in the final stage´|
|PSG sign Lo Celso|
|Muller: Beating Dortmund will be more fun this season|
|Juventus sign Higuain from Napoli for €90m|
|Pastore: I´m like God in Paris|
|Injured Lanzini out of Olympics|
|Allegri unperturbed by Higuain fee|
|Menezes replaces Bento at Cruzeiro|
|Sporting rejected major bids from Inter and Liverpool for Joao Mario, claims father|
|Pochettino pleased by Tottenham despite Juventus defeat|
|Eriksson: Allardyce the right man for England|
|Mourinho makes United train after stepping off plane from China|
|Hazard can still match Messi, says Pedro|
|Pjanic shows there is life at Juve, with or without Pogba|
|Juventus 2 Tottenham 1: Benatia bags win for Serie A champions|
|Dembele: I am not the Bundesliga´s next superstar|
|Lyon claim €35m Arsenal offer for Lacazette rejected|
|Donnarumma dreaming of Milan captaincy as he eyes long-term stay|
|Robson: Ibrahimovic can match Van Persie´s first year at United|
|Rooney should remain England captain - Eriksson|
|Emery wants new striker at PSG|
|Santos accept Juventus bid for Gabriel|
|Eriksson expects Sweden to try and tempt Ibrahimovic out of retirement|
|Spurs signing Janssen almost quit|
|Leicester stay best for Mahrez - Ranieri|
|Allardyce to take Mourinho cue on Rooney|
|Ings ready to outdo big-money signings|
|Henderson optimistic over Liverpool campaign|
|Allardyce hardened to the challenge of England post|
|Barcelona announce record revenues for 2015-16|
|Moyes enjoys Sunderland win as Palace beat Colchester|
|Stoke complete Allen signing|
|Roma coach Spalletti warns suitors off Manolas|
|Cresswell out for up to four months with knee injury|
|Burnley fan banned by club for racist abuse|
|Dad won´t let me play at the Olympics - Larsson Sr pulls rank|
|Kostic joins Hamburg on five-year deal|
|Tevez: I´d turn down Chelsea and Napoli to stay at Boca|
|Mayoral inspired by Benzema for Wolfsburg stint|
|Allardyce straight into competitive action with England|
|Liverpool, Sevilla fined for Europa League final incidents|
|Barcelona seal Guillemenot signing as part of new Servette deal|
|Niersbach handed one-year ban over World Cup corruption|
|Chelsea and Everton ´still interested´ as Koulibaly eyes Napoli exit|
|´Still working hard´ - Balotelli trains with Liverpool kids|
|Winter breaks, long-ball football and the World Cup: Allardyce in his own words|
|Inter warn Napoli Icardi is not for sale|
|Zanetti wants Simeone back at Inter|
|Stoke snap up Sobhi|
|PSG tougher under Emery - Lucas Moura|
|Totti not ready for retirement - Pallotta|
|Confident Allardyce reveals plan for England success|
|Pochettino to discard three Tottenham players|
|Allardyce: Rooney must wait for captaincy decision|
|Aubameyang: I will only leave Dortmund for Real Madrid|
|Allegri silences questions on Pogba|
|Bruce stands by decision to quit Hull City|
|Pochettino: Not the right time for Argentina job|
|Inter yet to approach De Boer with Mancini exit rumoured|
|Ancelotti trusts me more than Guardiola - Ribery|
|Wijnaldum rejected Everton for Klopp|
|Pre-season Manchester derby cancelled|
|Coutinho excited by ´fast´ Liverpool recruits|
|Cristiano Ronaldo and Conor McGregor step into the ring together|
|Mancini coy on reports linking Icardi to Napoli|
|Nolito reveals why he chose Man City over Barcelona|
|Inter 1 Paris Saint-Germain 3: Icardi absence in defeat fuels Napoli talk|