Sheffield United boss Nigel Clough played down the importance of making a strong start to the League One season, with Bristol City first up.
A poor opening to the 2013-14 campaign saw predecessor David Weir lose his job in October after taking just one win from 13 matches.
United subsequently turned to Clough as the man to lead the club out of the third tier of English football and a strong end to the term saw them narrowly miss out on the play-offs in seventh.
Clough also guided the side to the FA Cup semi-finals, with a 5-3 defeat to Hull City at Wembley ending their dreams, and that promising form has raised the already high expectation levels at a club who were in the Premier League just seven years ago.
Saturday's curtain-raiser sees United face another team who have been placed among the favourites for promotion, as Steve Cotterill's City outfit head north looking to put the disappointment of last season - when they finished 12th - firmly behind them.
The encounter promises to be a gripping contest, but Clough will not place too much stock in the result.
"It would be lovely to get off to a great start and be in the top few, but if we're not it's not the end of the world," he said.
"You're talking about a whole new team coming in. Some will settle quicker than others. If things don't go too brilliantly in the first three games we're not going to get too down about it because we'll have 43 to go."
United are joined in League One this season by South Yorkshire rivals Barnsley and Doncaster Rovers, who were both relegated from the Championship last season.
Danny Wilson has had a tough pre-season at Oakwell with Barnsley, as the likes of Luke Steele and Chris O'Grady have departed for pastures new.
However, Wilson is an experienced manager at League One level and will look to make a strong statement at home to Crawley Town.
Doncaster - who were subject to a failed takeover bid from former chairman John Ryan and One Direction star Louis Tomlinson in the close-season - start at Yeovil Town, who are also looking to bounce straight back to the Championship.
Leyton Orient are aiming to recover from May's play-off final defeat to Rotherham United, but face a tricky task on the opening day against a Chesterfield side buoyed by winning the League Two title last season.
Rochdale and Scunthorpe United both achieved automatic promotion to League One last term, with the former hosting last season's play-off semi-finalists Peterborough United, while the latter visit Swindon Town.
Fleetwood Town - who triumphed in the League Two play-off final - welcome Crewe Alexandra to Highbury.
Preston North End finished in the play-off positions in the 2013-14 campaign and start their attempt to reach the Championship at home to Notts County, while MK Dons welcome Gillingham.
Other matches see Bradford City take on Coventry City, Colchester United host Oldham Athletic and Walsall travel to Port Vale.
|Coach: N. Clough|
for R. Flynn 64'
for S. Scougall 76'
for C. Basham 86'
|Wenger criticism baffles Redknapp|
|Leicester must strengthen in window - Walsh|
|United not title contenders - Docherty|
|Koeman: Southampton youngsters will get a chance|
|Dyche empathises with Liverpool striker crisis|
|Cagliari turn to Zola|
|Rooney thanks Van Gaal for Christmas break|
|Cruzeiro offer Paulinho Tottenham exit chance|
|Carlisle´s wife grateful to Burnley|
|Katebe called up to Zambia AFCON squad|
|Cape Verde name AFCON squad|
|Finke names much-changed Cameroon squad|
|Grant omits World Cup troublemakers for AFCON|
|Blackpool striker Ranger goes AWOL|
|Allardyce relishing Mourinho meeting|
|Ashley fails to increase Rangers stake|
|Crystal Palace v Southampton: Koeman calls for focus|
|Warnock targeting striker in January|
|Chelsea v West Ham: Adrian vows visitors will attack|
|Heskey signs short-term deal at Bolton|
|Everton v Stoke City: Martinez eyes strong form|
|Juninho defends David Luiz|
|Burnley v Liverpool: Dyche defends Rodgers ahead of Turf Moor test|
|Arsenal v QPR: Wenger eyes festive momentum|
|Liverpool are growing in confidence, says Rodgers|
|Redknapp: Austin future could depend on survival|
|Martinez wants Everton consistency|
|Barca want Neymar until 2020, says agent|
|Jones undeterred by pressure of Liverpool starting role|
|Allardyce ´knows how to beat managers´ - Carroll|
|Jones playing for a new contract|
|China select Evergrande spine for Asian Cup|
|A-League Preview: Koren tips City to build|
|Khedira keen to fight for Real spot|
|Southampton confirm Elia deal|
|Cellino to remain as Leeds owner until after appeal|
|Manchester United v Newcastle United: Van Gaal demands domination|
|Van Gaal refuses to dismiss Bale speculation|
|Sunderland v Hull City: Bruce sure of Hull revival|
|Swansea City v Aston Villa: Lambert optimistic of away success|
|Agbonlahor red rescinded|
|Falcao depends on team-mates to perform - Van Gaal|
|Monk dismisses talk of Gomis move|
|West Brom v Manchester City: Pellegrini to experiment again|
|Xavi: I was ready for New York switch|
|Ibrahimovic fumes at awards snub|
|Irvine: No approaches for Berahino|
|Pearson determined to revive Leicester fortunes|
|League Two Preview: First host third as Wycombe meet Luton|
|League One Preview: Buoyant MK Dons eye more glory, Bristol City seek response|
|Championship Preview: Pritchard plotting to end Ipswich run, Bournemouth host Fulham|
|Kaboul place not guaranteed by captaincy - Pochettino|
|Koeman hopeful of Elia deal|
|Atletico president not ruling out Torres return|
|Swansea secure Oliveira signing|
|No excuses for Pellegrini|
|Walcott pace unaffected by injury|
|Former Real Madrid star Roberto Carlos backs Ronaldo for Ballon d´Or|
|Former PFA chairman Carlisle ´stable´ after serious incident|
|Balotelli remorse saved him from longer ban|
|Bayern midfielder Martinez ´on track´ with rehab|
|Pardew ´overjoyed´ at Gutierrez return|
|Spurs confirm Yedlin to join in January|
|Zeman sacked by Cagliari|
|Casillas: I´m going nowhere|
|Bruce demands McShane apology|
|Pulis would welcome Brighton talks|
|Buffon: Juve angry after Supercoppa loss|
|Arteta out until new year|
|Rangnick: Kampl deserves Dortmund switch|
|PFA offers support to Carlisle after serious incident|
|Napoli can mount title bid - Higuain|
|Cech´s agent urges Liverpool and Arsenal to make bid|
|Hart happy to be back to his best|
|Terry thrilled with ´revelation´ Matic|
|Perez rues ´unfair´ Tyne-Wear derby result|
|Khalfan Ibrahim returns from injury|
|Magath slams ´sensitive´ Fulham|
|´Limited´ attacking options inspire Postecoglou´s selections|
|Carlisle reportedly involved in serious incident|
|Primeira Liga Review: Braga leapfrog Guimaraes|
|Hughes upbeat despite Stoke defeat|