Swansea City coach Garry Monk hopes Michu will return before the end of the season, but conceded he will not feature this weekend.
The Spain international has started just three Premier League games since December after struggling with an ankle injury and, although close to a return, Monk says he will not be fit in time to face Aston Villa on Saturday.
Michu scored 22 goals last term after joining from Rayo Vallecano, but has found the net just six times this time in an injury-hit campaign.
"He's nearly there, but he just can't seem to get that swelling down," Monk said.
"He is going to see the national doctor in Spain, so we will know more after today (Thursday).
"I'm still hopeful that he will be able to play a part in the remainder of our season, but we have to be careful because it's important he gets the rest and comes back as strong as ever.
"Michu is a big player for us. He scores a lot of goals and is a quality striker.
"We're all disappointed for him, but he will be back fit and strong."
Monk is predicting a tough match against Villa and was adamant his side will not be resting easy after last week's 2-1 win at Newcastle United lifted them six points above the relegation zone.
Villa are a point below Swansea in 15th and have not lost in their last five matches.
"It won't be easy for us. No game is easy, especially at this time of the season," he added.
"Like us, Aston Villa are scrapping to secure their safety. They are a young side and are very energetic.
"We are expecting a really though game, and we can't take anything for granted.
"If we go into these next three games and don't get any other points while other teams win, we could be relegated.
"It's far from over for us. We have to go into Saturday's game to fight for three points. We have to make sure we are mathematically safe."
|20||J. de Guzmán|
|10||W. Bony||10' 90+4'|
|Coach: G. Monk|
for Àngel Rangel 77'
for J. de Guzmán 83'
for W. Routledge 88'
|Sampaoli: Taking Argentina job would be irresponsible|
|Payet absence no excuse - Noble|
|Gabriel Jesus expects Palmeiras exit amid Manchester City rumours|
|Domzale 2 West Ham 1: Crnic double stuns Bilic´s side|
|Juventus target Gabriel Barbosa says Santos exit is close|
|Leicester duo ready for ´once in a lifetime´ Champions League journey|
|Fabregas apologises for Klavan lunge|
|Reschke: Guardiola wanted Tuchel to be his successor|
|Pochettino expecting further Tottenham signings|
|Given retires from international football|
|Abdi and Pudil swap Watford for Wednesday|
|Leicester sign Chilwell to new five-year deal|
|Klopp pre-season ´most intense ever´ for Sturridge|
|Simeone backs Griezmann for Ballon d´Or final three|
|Puskas Award winner quits football - to become a gamer|
|Simeone: Champions League final felt like a death|
|Higuain: I have to prove my worth to Juventus|
|Guardiola confirms interest in Sane and Stones|
|Moreno set for Manchester City switch and Deportivo loan, claims agent|
|De Laurentiis pushed me into Juventus move - Higuain|
|Savic seeking to put injury woe behind him|
|Borussia Dortmund 1 Manchester City 1 (5-6 pens): Gunn´s shootout saves earn Guardiola first win|
|Oblak: Atleti need consistency and luck|
|Warburton rubbishes Van Persie rumours|
|Hospitalised Grujic ´can´t remember anything´, says Klopp|
|Premier League, Serie A appeal to Simeone|
|Copa Libertadores success ´a dream´ for Borja|
|Pochettino honoured by Simeone comparisons|
|Argentina have not asked for Sampaoli - Monchi|
|Ancelotti: Fitness the key for Bayern|
|Bayern win ´a small foundation´ for Montella´s Milan|
|Icardi missing due to injury - Mancini|
|Emery satisfied with warm-up win over Madrid|
|Conte quiet on Tevez, apologises for Fabregas red|
|´It was far from a friendly´ - Klopp on Chelsea defeat|
|Madrid off the pace, concedes Zidane|
|Chelsea 1 Liverpool 0: Cahill´s header seals win|
|Grujic says Chelsea´s Matic told him to sign for Liverpool|
|Bolasie wants to see Berahino and Benteke at Crystal Palace|
|Rodgers hails ´outstanding result´ as Celtic draw|
|Walcott claims level of MLS is close to Premier League|
|Bayern Munich 3 AC Milan 3 (3-5 on penalties): Bonaventura seals win|
|Atletico Nacional 1 Independiente del Valle 0 (2-1 agg): Borja secures Copa Libertadores crown|
|Icardi absent again as Inter held by Estudiantes|
|Real Madrid 1 Paris Saint-Germain 3: Zidane oversees poor pre-season start|
|Hazard vows to rediscover best Chelsea form|
|Klopp reveals why he sent Sakho back to Liverpool|
|Tevez: Conte wanted me at Chelsea|
|Sunderland hopeful Defoe will be fit for Man City opener|
|Sundowns overcome Zamalek to book semi-final spot|
|Falcao scores as Monaco return ends in defeat to Fenerbahce|
|Southampton overcome Twente, Asoro stars for Sunderland|
|Man City must adapt to Guardiola tactics quickly - Denayer|
|Chelsea and Leicester to play in EFL Trophy as five Premier League clubs refuse|
|Tolisso pulls plug on €37.5m Napoli move to stay at Lyon|
|Ancelotti shrugging off Guardiola´s shadow|
|Uruguay international Lodeiro swaps Boca for Seattle|
|Ibrahimovic will bring United back to where they belong - Larsson|
|Transfer speculation frustrates Aubameyang|
|Willian ready for ´toughest Premier League season in history´|
|Astana 1 Celtic 1: Griffiths hits late equaliser|
|De Laurentiis feels betrayed by Higuain swapping Napoli for Juventus|
|Costa: Chelsea cannot be any worse than last season|
|Wilshere: Xhaka can hold Arsenal midfield together|
|Pato signs four-year deal with Villarreal|
|Higuain sets sights on Champions League after Juventus move|
|Lazio snap up Immobile from Sevilla|
|Batshuayi worth the money, insists Cahill|
|Arnautovic signs new Stoke deal|
|Smith leaves Liverpool for Bournemouth|
|Barcelona insist Arda Turan will stay|
|Andre Gomes: Barcelona suit my identity better than Real Madrid|
|Niersbach to appeal FIFA ban|
|Barcelona agree Mascherano renewal|
|Fernandinho can play in 10 positions - Guardiola|
|Reading´s kit launch is out of this world|
|Ben Arfa: I do not want to be PSG´s star player|
|FA Cup to trial fourth substitute|
|We want Balotelli and he wants us, says Besiktas chief|
|Crowd welcomes Higuain as he arrives for Juventus medical|
|Guardiola warns Man City stars: If you´re not fit, danger is coming|
|Mkhitaryan prepares to prove himself at United|
|Cavani: No pressure replacing Ibrahimovic|
|Wenger vows to keep transfer plans ´secret´ after Lacazette snub|
|Brannagan open to Championship loan move|
|Wenger wants to sign Mertesacker replacement|
|Ancelotti: Bayern´s transfer business done|
|Brisbane Roar sign former Danish international Kristensen|
|Verratti, Luiz missing for PSG|
|Sounders part ways with foundation coach Schmid|
|Mane turned down Manchester United for Liverpool|
|Zidane on Pogba: Until August 31, anything can happen|
|Mkhitaryan driven by father´s death|
|Inter rejected Napoli offer for Icardi, says president|
|Clichy: City fighting fit after Guardiola pizza ban|
|Everton and Burnley win as Hull are held|
|Ajax held by PAOK after Cillessen howler|
|Conte left frustrated by ´crazy´ money in transfer market|