Roma's chances of keeping the pressure on Serie A leaders Juventus faces a major test when they visit Fiorentina on Saturday.
Rudi Garcia's side are eight points adrift of the two-time defending champions with five league matches remaining.
Overhauling Antonio Conte's team would take something special, and extending their seven-match winning streak is a must for Roma.
Juve are at home to Bologna earlier on Saturday, meaning the gap could be 11 points before Roma's kick-off.
Roma attacking midfielder Adem Ljajic takes on his former club, but his future may lay elsewhere as he looks for regular opportunities.
The talented Serbia international has been linked with several clubs, and a move looks set to happen in the off-season.
With Mattia Destro, Gervinho and Francesco Totti in form, it has been tough for Ljajic to break in for a regular start.
Fiorentina sit fourth and still have slim hopes of finishing third and sealing a place in the qualifiers for the UEFA Champions League.
Napoli, who occupy third place, travel to Udinese on Saturday and would need a late-season form slump to give up the spot they sit nine points clear in.
Inter cling onto the final UEFA Europa League place ahead of a crucial clash at Parma.
Walter Mazzarri's men are two points clear of Parma, who will be desperately chasing all three points to move into fifth.
At the other end of the table, Livorno, Sassuolo and Catania continue their bids to move out of the relegation zone.
Livorno, three points adrift of 17th-placed Bologna, are unlikely to make ground as they travel to an in-form Milan side.
Sassuolo have a chance to draw level on points with Bologna as they face fellow strugglers Chievo.
Catania, who would need a miracle to avoid the drop, host Sampdoria, and a win would bring them to within five points of safety.
Elsewhere, lower-table sides Genoa and Cagliari do battle, Atalanta host Verona and Lazio welcome Torino to the Stadio Olimpico.
|Coach: V. Montella|
for Ryder Matos 46'
for J. Iličić 73'
for A. Aquilani 81'
|Bertrand joins Southampton on loan|
|Van Aanholt features as Sunderland fall to defeat|
|UEFA Champions League Review: Celtic hammered in Warsaw|
|Collison stakes his claim as QPR are held|
|Newcastle youngsters edge to Wednesday win|
|Villa beaten by buoyant Chesterfield|
|Juve held by new boys Cesena|
|Late Drinkwater strike helps Leicester see off Walsall|
|Everton seal club-record Lukaku deal|
|Lazio complete De Vrij capture|
|Fabregas opens account in Chelsea win|
|AFA president Grondona dies aged 82|
|Trezeguet heading for Indian Super League|
|Premier League to introduce vanishing foam|
|Rennes bring in Bruls|
|Kehl steps down as Dortmund captain|
|Capello: I´m staying until 2018|
|Pedro saddened by Fabregas departure|
|Fernandez agrees Porto switch|
|West Ham close on Jenkinson, says Allardyce|
|Donnelly out for three months|
|Chambers: It has been a whirlwind|
|Lukaku drops Chelsea exit hint|
|Mee signs new deal at Burnley|
|Lovren denied United States visa|
|Redknapp admits Fer interest|
|No official Cuadrado bids, insists agent|
|Maguire ready to make step up|
|Rodgers: Liverpool have a strategy in transfer market|
|Ki out to prove himself at Swansea|
|Garcia plays down importance of Real scalp|
|Evian complete Bruno signing|
|Poyet frustrated by lack of new faces|
|Mexes convinced Milan are improving|
|Mazzarri praises Inter attitude|
|Ronaldo could face Manchester United - Ancelotti|
|Tevez thanks fans after father found ´safe and well´|
|Gabi braced to tackle big-spending rivals|
|Shaw: I deserved Van Gaal criticism|
|Morinigo surprised by Gedoz substitution|
|Honduras appoint Medford|
|Van Gaal delighted with United display|
|Roma battle past Real Madrid|
|Simeone talks up Hernandez transfer|
|Defensor Sporting 1 Nacional Asuncion 0 (1-2 agg): Visitors into final despite loss|
|United edge Inter on penalties|
|Gerrard: It´s been ´the worst three months of my life´|
|Sabella set to quit Argentina post|
|Toure plans to see out career with City|
|Tevez´s father released after kidnapping|
|Benitez denies Callejon spat|
|Brownhill stunner downs Burnley|
|Sunderland edge out Recreativo|
|Barton and Hoilett earn QPR draw|
|UEFA Champions League Review: Lafata treble puts Sparta in command, Slovan beat Sheriff|
|Gomis opens Swansea account at Exeter|
|Schneiderlin hints at Southampton discontent|
|Scolari makes Gremio return|
|Bojan strike in vain as Schalke beat Stoke|
|Tevez to miss friendly amid kidnap reports|
|Porto sign Jose Angel from Roma|
|UEFA Europa League Preview: Trencin v Hull City|
|Liverpool land Origi|
|UEFA Europa League Preview: Torino return to Europe after 20-year absence|
|Rodriguez and Schneiderlin not for sale, say Southampton|
|Rakitic: Not all about front three|
|Barkley pens new Everton deal|
|Guardiola relishing Chivas friendly|
|Drogba targets Premier League glory|
|Hull make Maguire and Robertson double swoop|
|Perisic blow for Wolfsburg|
|Ibrahimovic scores hat-trick as PSG hammer Kitchee|
|Al-Hilal coach sacked over referee row|
|La Liga boss wants cream of the crop|
|Valencia granted work permit, completes West Ham move|
|Atletico complete deal for Griezmann|
|Reus focused on fitness battle despite ´major European interest´|
|Barcelona announce club-record revenue|
|Bony could be sold for right price, says Jenkins|
|Confidence key for Newcastle, says Taylor|
|Saivet out for four weeks with knee injury|
|Genk part company with Ferrera after just one game of season|
|Gold clarifies Twitter gaffe|
|Vidic adapting to different style at Inter|
|Toulouse bring in Matheus|
|Butragueno backs Rodriguez to cope with pressure|
|Benteke aiming to come back stronger|
|Valdez joins Frankfurt|
|Jovetic ready to shine|
|Simeone hails Griezmann qualities|
|Monk unsure over De Guzman future|
|Benitez: Michu will take time to adjust|
|Diaby confident of staying fit|
|Shaw not fit enough, says Van Gaal|
|MLS Preview: RSL look for attacking spark|
|Monk slaps ´astronomical´ price on Bony´s head|
|Australian clubs looking at Ronaldinho|
|Sinclair enjoying ´one of the best pre-seasons´|
|Spiranovic surgery a success|
|Seattle Sounders 0 Los Angeles Galaxy 3: First-half blitz fires Californians to victory|
|Lemina thrilled with Bielsa effect|
|Bayern´s Green chomping at the bit|
|Palace complete US tour with easy win|
|Carragher: Liverpool didn´t want me|
|Simeone: Atleti´s La Liga triumph was no fluke|
|Sturridge: ´I´ll step up´|
|Van Gaal: Formation gives United flexibility|
|Mathieu insists age is no barrier|
|Martinez the deal sealer, says Besic|
|Coaches embrace blockbuster Serie A start|