Brentford can erase the nightmare of last season on Friday by securing promotion to the Championship when they host Preston North End.
Mark Warburton's men sit seven points clear of third-placed Leyton Orient with four games remaining, knowing that victory over Preston combined with defeat for Orient and Rotherham United failing to win would see them return to the second tier for the first time since 1993.
Brentford were denied promotion last season by a stunning last-minute defeat to Doncaster Rovers, before another loss to Yeovil Town in the play-off final compounded their misery.
Warburton insists that disappointment has helped focus his players on the challenge ahead.
"They learned from last year. They've moved on from last year," he told The Evening Standard.
"Our target, in a non-arrogant way, is to win four out of four, to secure promotion."
Facing an in-form Preston side will not be easy, though, and Simon Grayson's men could still catch their opponents should they secure victory at Griffin Park.
Rotherham will likely have to settle for the play-offs and will need to beat league leaders, and title chasers, Wolves to keep their top-two hopes alive, while Orient travel to Crawley Town, who practically secured survival with a midweek win over Tranmere Rovers.
Peterborough United's return to form has boosted their hopes of a top-six finish and they travel to Bradford City, while Swindon Town, in seventh, will look to keep the pressure on Darren Ferguson's side when they visit Coventry City.
Port Vale entertain MK Dons at Vale Park in a clash of two sides whose play-off push looks to have come too late.
Rock-bottom Stevenage need to get back to winning ways if they are to survive and they travel to a Sheffield United side looking to bounce back after a dramatic 5-3 defeat to Hull City in the FA Cup semi-finals on Sunday.
Though manager Graham Westley has not led his side to victory in eight games, they are just four points behind 20t-placed Notts County, who will hope that a run of four wins from five can be improved further at Bristol City.
Two of the sides in the drop zone meet as Shrewsbury Town welcome Crewe Alexandra, while Carlisle United, who face Walsall, are in the bottom four due to their inferior goal difference to Notts County.
Tranmere remain just three points above the drop zone ahead of their trip to Gillingham, who may have enough to keep their head above water, and Colchester United host Oldham Athletic with a win likely enough to secure safety for either team.
|Terry: Too long between titles|
|Pepe puts Morata friendship aside for Champions League match-up|
|Hazard can be as good as Messi, Ronaldo - Fabregas|
|Carlisle ´deeply ashamed´ about suicide attempt|
|Tevez planning to win Champions League with Juve|
|Blatter ´knows absolutely nothing´ - Maradona|
|Allegri: Ancelotti a smart man|
|Sunderland academy coach to manage Oldham|
|Primeira Liga Review: Braga secure Europa League berth|
|Bruce backing Hull to respond against Burnley|
|Almeria 2 Celta Vigo 2: Bifouma, Zongo inspire hosts´ comeback|
|Arsenal can mount title bid - Wenger|
|Turkish Super Lig Review: Besiktas and Galatasaray remain locked at the top|
|Cagliari 4 Parma 0: Festa revival back in gear|
|Hull City 1 Arsenal 3: Sanchez at the double as visitors close on second|
|Blackpool - Huddersfield game will not be finished|
|Allegri vindicated by Juventus success|
|Russian Premier League Review: Krasnodar close the gap as Zenit slip up|
|Al Ahly dismiss Garrido|
|MLS Preview: Kinnear returns to Dynamo with Earthquakes|
|Ancelotti all out for victory against Juventus|
|Ramires recovering well after sickness|
|Prince Ali would back rival FIFA candidate to oust Blatter|
|Barcelona v Bayern Munich: Guardiola makes Camp Nou return|
|Kruse a target for Wolfsburg - Allofs|
|Fletcher backing Bournemouth to ´surprise a few´|
|Bremen agree deal with Fritz|
|Carver gets Newcastle backing|
|Blaszczykowski suffers groin tear|
|Boateng warns of Barca ´storm´|
|Brouwers agrees Gladbach extension|
|Benzema to miss Turin trip|
|England great Jimmy Greaves suffers stroke|
|Cabaye concerned by bit-part role at PSG|
|Parry: Anfield expansion a major boost|
|Ki targets Arsenal win and seventh spot|
|Pirlo eyes potential Champions League swansong|
|Mourinho rounds on critics after clinching title|
|Henderson: Liverpool can push on without Gerrard|
|Lack of goals a concern for Van Gaal|
|Hard to keep Benteke - Bacuna|
|MLS Review: Sporting KC end Chicago streak, Martins brace furthers NYC pain|
|Copa Libertadores Preview: River eye revenge in Superclasico|
|Garcia lauds ´impressive´ Roma|
|Pavon goal scores him a BMW for a month|
|Boca beat River in Superclasico|
|Inzaghi to blood youth after third straight Milan defeat|
|Blanc urges PSG to ´remain vigilant´|
|La Liga Review: Valencia go clear of Sevilla, crisis-stricken Elche safe|
|CAF Champions League Review: ES Tunis dumped out by Al Merreikh|
|Masterful Mourinho has Premier League and Chelsea singing his tune|
|Nantes 0 Paris Saint-Germain 2: Cavani nets again as Ibrahimovic returns|
|Napoli 3 Milan 0: Late treble saves hosts|
|Primeira Liga Review: Porto edge past strugglers Vitoria|
|Bundesliga Review: Hamburg claim last-gasp winner, Gladbach close in on Wolfsburg|
|Pochettino: Hart heroics the difference|
|Ligue 1 Review: Monaco remain on course for third, Lille cruise past Lens|
|Pellegrini silent over City future|
|Rome derby not on Lazio´s radar, says Pioli|
|Pardew laments penalty calls in Palace´s loss to champions|
|Serie A Review: Roma move back into second, Di Natale overtakes Baggio|
|Tottenham 0 Manchester City 1: Aguero heaps more misery on Spurs|
|Mourinho appears to take dig at old nemesis Guardiola|
|Mancini frustrated by resilient Chievo|
|Drogba coy over future after title triumph|
|Chelsea title win will not lead to domination - Mourinho|
|Inter 0 Chievo 0: More frustration for Mancini|
|Terry: I´ve proved Benitez wrong|
|BREAKING NEWS: Chelsea secure Premier League title|
|Chelsea 1 Crystal Palace 0: Title heads back to Stamford Bridge|
|League One Review: MK Dons promoted, as Orient, Notts County and Crawley go down|
|Dortmund striker Ramos set to miss Copa America|
|Williamson denies getting sent off on purpose|
|Eintracht Frankfurt´s Kittel suffers injury blow|
|Juventus v Real Madrid: Serie A kings set for Real test|
|United still control top-four destiny - Young|
|Record finish beyond Stoke - Hughes|
|Wellington Phoenix 0 Melbourne City 2: Surprise win sets up semi-final derby|
|Vidal already focused on Real|
|MLS Review: Revs hand Red Bulls first loss|
|AFC Champions League Preview: Wanderers facing elimination|
|Lyon stepped up despite pressure - Fournier|
|Gerrard anticipating emotional Anfield finale|
|´I´ve always wanted to score a free-kick past Neuer´ - Calhanoglu|
|Negredo: Pellegrini lost faith in me|
|Buffon had title doubts after Conte departure|
|Luis Enrique: I was worried during 8-0 win|
|Wilshere will return to his best - Wenger|
|Rodgers unconcerned by banner|
|Mourinho doesn´t want guard of honour|
|Deportivo La Coruna 1 Villarreal 1: Hosts come from behind|
|Juve canter to title success as Allegri wins over doubters|