Atletico Madrid restored their lead at the top of La Liga by beating 10-man Getafe 2-0, but an injury to Diego Costa overshadowed the win.
Talismanic striker Costa scored the second on Sunday to re-establish a three-point lead over city rivals Real at the summit, but he paid the price for his bravery in sliding home from close range to wrap up the victory.
The 25-year-old - who has only just returned from a hamstring strain - collided with the post in the act of scoring, appearing to take a heavy blow to his leg, and was carried off on a stretcher in clear discomfort.
With the extent of the injury sure to be a concern for coach Diego Simeone at such a pivotal stage of the season, that setback took the gloss off a battling performance that had capped off a remarkable week.
The league leaders secured a UEFA Champions League semi-final berth on Wednesday by beating Barcelona and they avoided a European hangover when Diego Godin headed them into a first-half lead.
Costa's goal came after he had already missed from the penalty spot, with Angel Lafita's red card compounding a difficult game for Cosmin Contra's relegation-threatened Getafe side.
Following the victory against Gerardo Martino's Barca, Simeone had demanded full focus from his side - but despite that, Atletico seemed lacklustre in the early stages.
Alexis almost put the hosts ahead in the 19th minute, only to head Pedro Leon's corner agonisingly wide.
That let-off seemed to jolt Atletico into action, though.
After 28 minutes, Godin spurned a glorious chance as he rose to meet Koke's right-wing free-kick but nodded the ball straight at Jordi Codina in the Getafe goal.
Godin was not denied next time, however.
The Uruguayan out-jumped Roberto Lago at the back post in the 40th minute, looping a powerful headed effort over Codina following Juanfran's lofted cross-field pass.
Getafe started the second half with renewed determination and they were almost rewarded with an equaliser, but the unmarked Juan Rodriguez could only head Leon's right-wing cross straight at Thibaut Courtois before the home side were the architects of their own downfall in the 64th minute.
Lafita hauled down centre-back Miranda inside the area and was shown a straight red card, but Atletico could not capitalise as Costa saw his spot-kick saved by Codina.
The frustrated Costa finally doubled Atletico's lead in the 84th minute, as he tapped Adrian Lopez's pass in at the back post, but the Spain international suffered a nasty leg injury as he collided with the frame of the goal, with a gash visible just below his knee as he received treatment.
With several of his team-mates signalling to the bench, he was soon carried off on a stretcher, and Atletico played out the final few minutes with little more action of note.
|Coach: C. Contra|
for Diego Castro 57'
for Pedro Mosquera 68'
for Roberto Lago 80'
|It will take years to build football culture, Wenger warns CSL|
|´Worried´ Rakitic wants Barca renewal|
|Inter not signing Messi - Moratti|
|Luis Enrique hails Barca defence after ending Anoeta curse|
|´He is made of different stuff´ - Spalletti hails Nainggolan after wondergoal|
|Tottenham´s Janssen turned down Galatasaray move, agent claims|
|Did Carroll´s wondergoal give the West Ham striker whiplash?|
|Iniesta suffers calf injury|
|Swansea situation not ´hopeless´, says Clement|
|Real Sociedad 0 Barcelona 1: Neymar ends Anoeta curse|
|´Immeasurable bulls**t´ - Ligue 1 coach destroys Van Basten´s offside plan|
|Simeone praises Atletico´s precision in Copa Del Rey win|
|Fonte situation difficult for Southampton - Puel|
|´Some of the best football in the UK´ - Watford´s Mazzarri hails Bournemouth|
|Senegal 2 Zimbabwe 0: Cisse´s men charge into quarter-finals|
|Rivaldo backs Luis Enrique to deliver more Barca success|
|Atletico Madrid 3 Eibar 0: Routine win earns quarter-final lead|
|Jesus will make Premier League history - Rivaldo|
|Adebayor: Arsenal are just Ozil and Sanchez|
|Algeria 1 Tunisia 2: Favourites on brink of elimination|
|Bayern keen to seal Coman deal as Rummenigge cools Gnabry interest|
|Pochettino has done his homework on Jesus as Spurs look to march on|
|Scrap offside? Premier League managers give Van Basten´s plans a cool reception|
|Coman ready for Bayern comeback, confirms Ancelotti|
|Pochettino upbeat despite six weeks out for Vertonghen, Lamela still a mystery|
|Cerezo defiant over Griezmann amid talk of Manchester United agreement|
|Robinho named in Brazil squad for Chapecoense fundraiser|
|Davies and Lookman aren´t the big men of Everton, warns Koeman|
|Ivory Coast v DR Congo: Dussyer demands champions show true strength|
|Replacing Robben and Ribery not easy - Hitzfeld|
|Yeray back in Athletic training after successful cancer surgery|
|Karanka targeting more Boro deals after Bamford swoop|
|Cavani: I am the ultimate finisher|
|Morocco v Togo: El Ahmadi hungry for success|
|Ancelotti denies Verratti approach|
|A-League Review: Cahill double sees Melbourne City sink Mariners|
|Manchester United very happy with Shaw, insists agent|
|Mertesacker extends Arsenal deal|
|Boost for Arsenal as key quartet returns to training|
|Will Jesus save Manchester City´s title bid? Guardiola´s new striker in Opta numbers|
|Tevez mobbed after touching down in Shanghai|
|Payet exit not inevitable - Bilic|
|Wenger: Arsenal don´t need Payet|
|Jesus wants Manchester City titles|
|Orsolini arrives for Juventus medical|
|Rivaldo backs Coutinho to join Neymar at Barcelona|
|No danger of Messi leaving Barcelona, says father|
|Augusto: I convinced Oscar to come to China|
|Madrid-bound Maradona visits Napoli training|
|Sevilla in no rush over Sampaoli talks despite Barcelona links|
|Cafu: Resurgent Brazil can challenge world´s best|
|Klopp thrilled with Coutinho|
|Manchester United replace Real Madrid as world´s richest club|
|Madrid squad annoyed by defeats - Zidane wants more energy after latest loss|
|Casemiro rues more misery for Madrid against Celta|
|´Job done, let´s go home´ - Klopp happy to avoid extra time with narrow Plymouth win|
|FA Cup Review: Southampton leave it late to beat Norwich|
|Real Madrid 1 Celta Vigo 2: Aspas and Jonny extend Madrid winless run|
|Plymouth Argyle 0 Liverpool 1: Rare Lucas goal sees Klopp´s men through|
|Manchester City in La La Land as Schalke toil underground|
|Cameroon 2 Guinea-Bissau 1: Ngadeu-Ngadjui completes comeback to send Broos´ men top|
|Monaco confirm signing of Ajax teenager Antonucci|
|Manchester United´s interest in Griezmann is unsurprising - Simeone|
|Bamford ends spell in Chelsea wilderness with Boro return|
|Louis the great - Luis Enrique explains his and Barca´s debt to Van Gaal|
|Gabon 1 Burkina Faso 1: Spot-on Aubameyang makes his point|
|PSG send Ikone on loan to Montpellier|
|Senegal v Zimbabwe: Cisse wants to live up to favourites tag|
|Ghana´s Rahman leaves AFCON with knee injury|
|Algeria v Tunisia: Mahrez demands improvement in crucial Group B clash|
|Dortmund forward Dembele hits out at Bundesliga refereeing|
|Robben hopes Alonso stays at Bayern amid retirement rumours|
|Asian champions Jeonbuk banned from 2017 Champions League|
|Rakitic still an important player for Barcelona - Luis Enrique|
|Jesus will develop quicker at City - Emerson|
|Always take the weather with you - Spanish snow blights CSKA´s training camp|
|Messi never gave Coach interview, claims father|
|Gotze questions critics but admits to falling short of expecations|
|´Conte can have our title´ - Ranieri wants Chelsea to win the Premier League|
|Tottenham reject Premier League, Bundesliga offers for Wimmer|
|Liverpool sell Ilori to Reading|
|Potential victims in football abuse probe surpasses 500|
|Bonaventura signs new AC Milan contract|
|Messi: Ronaldo has achieved great things|
|Koscielny: Wenger has built men at Arsenal|
|Messi vows to stay at Barcelona ´for as long as they want me´|
|Cafu adamant Neymar will become world´s best|
|I´m just taking a sabbatical - Van Gaal denies he´s retired|
|Not even Gerrard won Premier League - Buttner says he´s not a United flop|
|Samper ignored Wenger as Barca midfielder rejected Arsenal|
|Pleased Pioli wants more from Inter|
|Evergrande boss Scolari dismisses Turan links|
|Klopp seeks legal advice over Matip|
|Marseille complete Sanson move|