Barcelona’s dismal week took another turn for the worse as they crashed to a shock 1-0 La Liga defeat at Granada on Saturday.
Yacine Brahimi's third goal of the season in the first half gave the Andalucian outfit their first win over the champions since they returned to the top flight in the 2011-12 campaign.
Barca were dumped out of the UEFA Champions League at the quarter-final stage by Liga title rivals Atletico Madrid in midweek, and the pressure on coach Gerardo Martino was ramped up again at Estadio Nuevo Los Carmenes.
Neymar cut a frustated figure as he spurned several chances, and defeat ensured Barca missed the chance to replace Atletico - who play on Sunday - at the top of the table, while victory for Granada eased their relegation fears.
Martino stated in the build-up to this game that Barca's season would be deemed a failure following their Champions League exit, and he must now hope his side respond by winning the Copa del Rey final against Real Madrid on Wednesday.
Xavi, Jordi Alba and Dani Alves dropped to the bench as Martino rang the changes following the loss at Atletico and, probably, with one eye on the Copa final.
Barca made a bright start, but they were stunned when the home side took the lead just 16 minutes in.
Midfielder Fran Rico was the architect, with a pass that pierced the Barca defence, and Brahimi raced away from Martin Montoya before beating Jose Pinto with a right-foot finish inside the near post.
Granada wanted a penalty when Youssef El-Arabi went down under a challenge from Javier Mascherano, but referee Carlos Delgado saw nothing untoward.
Neymar should have done better when he headed Montoya's inviting cross over the crossbar, before the Brazil forward tried his luck with a measured right-foot strike from outside the area that was palmed away by Orestis Karnezis.
Former Santos man Neymar was becoming increasingly tetchy, and he was somewhat fortunate to escape with only a yellow card when he kicked out at Allan Nyom just before half-time.
Barca got straight back on the front foot after the break and Granada were indebted to a fine save from Karnezis to keep out a Cesc Fabregas strike that looked destined for the back of the net.
Neymar was wasteful once again when he fired a left-foot strike wide of the far post 12 minutes into the second half as the home side came under yet more pressure.
Karnezis then thwarted Barca again with an outstanding reflex save from a Lionel Messi free-kick, before smothering Sergio Busquets' strike from close range.
Neymar's misery continued 17 minutes from time when he volleyed wide at the far post, and Andres Iniesta then flashed a shot just wide of the far post.
El-Arabi could have sealed the points three minutes from time when he raced through on goal, but Pinto denied him.
That miss was not to prove costly, though, as the home side held on for three precious points in their battle to avoid the drop and dealt a big blow to Barca's title hopes.
|Coach: Lucas Alcaraz|
|Albania v Portugal: Winners will be all-but qualified|
|Scotland v Germany: Low expects smarting Scots to attack|
|France v Serbia: Deschamps eyes winning run|
|´Where are the stars of Manchester United?´ - Queiroz hits out at Moyes and Van Gaal|
|Sneijder demands improved display from Netherlands|
|Real Madrid make €1m pledge to help refugees|
|Ings: I can learn from ´fantastic´ Sturridge|
|Ozil: Scotland won´t stop us|
|Portugal will be better than France - Santos|
|Kruse: I am 100 per cent fit|
|Mexico 3 Trinidad and Tobago 3: Herrera the hero for Ferretti´s men|
|FFA expect Tajikistan match to go ahead despite Dushanbe violence|
|Panama 0 Uruguay 1: Stuani´s late header clinches win|
|CONCACAF World Cup Qualifying Review: Jamaica stunned, Canada win|
|Argentina 7 Bolivia 0: Aguero, Messi star in rout|
|Canada 3 Belize 0: Hosts dominate in Toronto|
|Chelsea ´warehousing´ players - PFA chief|
|United States 2 Peru 1: Altidore inspires hosts´ comeback|
|Argentina 7-0 Bolivia: Aguero, Messi & Lavezzi net doubles in rout|
|Del Bosque unmoved by calls for two strikers|
|Deschamps praise for beautiful France|
|Fekir ruptures knee ligaments|
|Italy v Bulgaria: Conte warns against complacency|
|Euro 2016 Qualifiers Review: Germany top Group D, Northern Ireland edge closer|
|Low: Three points most important|
|Northern Ireland on the verge of a ´magnificent achievement´ - O´Neill|
|Scotland need something against Germany - Strachan|
|Portugal 0 France 1: Late Valbuena set-piece clinches deserved win|
|Faroe Islands 1 Northern Ireland 3: O´Neill´s men edge closer|
|Germany 3 Poland 1: Gotze sends world champions top|
|Gibraltar 0 Republic of Ireland 4: Irish hopes reignited|
|Djibouti 0 Togo 2: Saintfiet´s side make it two wins from two|
|Cyprus v Belgium: Benteke boost for Wilmots´ men|
|Roma youngster faces lengthy lay-off|
|United hit back at Perez barb over De Gea saga|
|Georgia 1 Scotland 0: Strachan´s men succumb to Tbilisi hoodoo|
|Hodgson prepared to blood new players|
|Porto invite Euro elite to help raise millions for migrants|
|Dortmund legend Dede backs Tuchel to succeed|
|Robben out for four weeks|
|Turkey v Netherlands: Terim expecting hostile atmosphere for crunch clash|
|Portugal 0-1 France: Valbuena strikes late to sink Ronaldo & Co|
|Wales v Israel: Euro 2016 beckons for Coleman´s history boys|
|Gala: No extra payment for Grosskreutz|
|Increase Bundesliga´s TV rights or be left behind - Rummenigge|
|Kane: I´m no flash in the pan|
|Perez: United showed inexperience in De Gea saga|
|Milligan: Socceroos wary of Tajikistan|
|Conte wants more players like Pelle|
|OFC World Cup Qualifying Review: Samoa to meet Tahiti in next round|
|Krychowiak stayed at Sevilla because of Emery|
|I never considered Bayern exit - Gotze|
|Balotelli ´not in good condition´, Milan must improve - Mihajlovic|
|Robben slams ´stupid´ Martins Indi|
|Robben laments injury blow|
|Euro 2016 Qualifiers Review: Bale edges Wales closer, Iceland dent Netherlands´ qualification hopes|
|De Bruyne relieved to ´boss´ Bosnia-Herzegovina|
|Blind furious after nightmare debut|
|Coleman sees shades of Charles in Bale winner|
|Conte only concerned about Italy winning|
|Mauritania v South Africa: SAFA to investigate Masilela no-show|
|AFC World Cup Qualifying Review: Qatar hit 15 in Bhutan rout|
|Belgium 3 Bosnia-Herzegovina 1: De Bruyne shines in straightforward victory|
|Cyprus 0 Wales 1: Bale winner takes Wales one step closer|
|Netherlands 0 Iceland 1: Sigurdsson winner caps difficult first game for Blind|
|Italy 1 Malta 0: Pelle spares wasteful Azzurri|
|Balotelli stars in Milan friendly win|
|Bhutan thrashed 15-0 by Qatar in qualifier|
|Rwanda v Ghana: Gyan doubt gives hosts hope|
|Tanzania v Nigeria: Enyeama out of AFCON qualifier|
|Valdes and Berahino included in Premier League squads|
|Costa Rica v Brazil: Dunga´s men return after Copa disappointment|
|Spain v Slovakia: Azpilicueta eyeing important revenge|
|Adebayor left out of Tottenham squad list for league and Europe|
|San Marino v England: Place in history books beckons for Rooney|
|Germany can cope with Reus absence - Low|
|Bayern offer aid to refugees in ´training camp´|
|BREAKING NEWS: Welbeck ruled out for months after knee surgery|
|South Korea 8 Laos 0: Son leads the way in rout|
|Australia 5 Bangladesh 0: Socceroos surge to emphatic win|
|Japan 3 Cambodia 0: Hosts pick up first qualifying win|
|Rudiger aiming to nail down Euros spot after Roma move|
|Melo happy to join Inter at last|
|Hernandez thanks Ferguson after United departure|
|Chung: AFC has compromised FIFA election|
|Wales the new best of British|
|Reus out of Germany qualifiers|
|Chile v Paraguay: Vidal missing for Copa champions|
|Ghedin: Anything is possible for Malta|
|Pogba will be worth €100m - Marotta|
|England can win Euro 2016 - Hodgson tells players|
|Conte unsure over Balotelli future|
|Argentina - Bolivia Preview: Mascherano backs 'very special' Messi|
|Portugal - France Preview: Deschamps aiming to correct mistakes|