Barcelona’s dismal week took another turn for the worse as they crashed to a shock 1-0 La Liga defeat at Granada on Saturday.
Yacine Brahimi's third goal of the season in the first half gave the Andalucian outfit their first win over the champions since they returned to the top flight in the 2011-12 campaign.
Barca were dumped out of the UEFA Champions League at the quarter-final stage by Liga title rivals Atletico Madrid in midweek, and the pressure on coach Gerardo Martino was ramped up again at Estadio Nuevo Los Carmenes.
Neymar cut a frustated figure as he spurned several chances, and defeat ensured Barca missed the chance to replace Atletico - who play on Sunday - at the top of the table, while victory for Granada eased their relegation fears.
Martino stated in the build-up to this game that Barca's season would be deemed a failure following their Champions League exit, and he must now hope his side respond by winning the Copa del Rey final against Real Madrid on Wednesday.
Xavi, Jordi Alba and Dani Alves dropped to the bench as Martino rang the changes following the loss at Atletico and, probably, with one eye on the Copa final.
Barca made a bright start, but they were stunned when the home side took the lead just 16 minutes in.
Midfielder Fran Rico was the architect, with a pass that pierced the Barca defence, and Brahimi raced away from Martin Montoya before beating Jose Pinto with a right-foot finish inside the near post.
Granada wanted a penalty when Youssef El-Arabi went down under a challenge from Javier Mascherano, but referee Carlos Delgado saw nothing untoward.
Neymar should have done better when he headed Montoya's inviting cross over the crossbar, before the Brazil forward tried his luck with a measured right-foot strike from outside the area that was palmed away by Orestis Karnezis.
Former Santos man Neymar was becoming increasingly tetchy, and he was somewhat fortunate to escape with only a yellow card when he kicked out at Allan Nyom just before half-time.
Barca got straight back on the front foot after the break and Granada were indebted to a fine save from Karnezis to keep out a Cesc Fabregas strike that looked destined for the back of the net.
Neymar was wasteful once again when he fired a left-foot strike wide of the far post 12 minutes into the second half as the home side came under yet more pressure.
Karnezis then thwarted Barca again with an outstanding reflex save from a Lionel Messi free-kick, before smothering Sergio Busquets' strike from close range.
Neymar's misery continued 17 minutes from time when he volleyed wide at the far post, and Andres Iniesta then flashed a shot just wide of the far post.
El-Arabi could have sealed the points three minutes from time when he raced through on goal, but Pinto denied him.
That miss was not to prove costly, though, as the home side held on for three precious points in their battle to avoid the drop and dealt a big blow to Barca's title hopes.
|Coach: Lucas Alcaraz|
|UEFA Europa League Review: Lovren misses crucial spot kick as Liverpool crash out|
|Rodgers rues lack of Liverpool guile|
|Pochettino laments ´key´ Soldado miss|
|Everton 3 Young Boys 1 (7-2 agg): Tormentor-in-chief Lukaku on song again|
|Serie A games to start late in show of support for Parma|
|Mancini irked by mistakes despite win|
|Besiktas 1 Liverpool 0 (aet, 1-1 agg, 5-4 pens): Lovren misses decisive spot-kick|
|Chelsea agree record sponsorship deal|
|Fiorentina 2 Tottenham 0 (3-1 agg): Gomez and Salah eliminate Spurs|
|Inter 1 Celtic 0 (4-3 agg): Guarin stunner sees Mancini´s men through|
|Manchester United v Sunderland: Poyet eyeing another Old Trafford upset|
|Monk has no problem with Van Gaal|
|Borussia Dortmund v Schalke: Di Matteo buzzing ahead of derby debut|
|Poyet not prepared to risk returning duo against United|
|Sherwood seeks six wins for survival|
|Championship Preview: Neil relishing East Anglian derby|
|Newcastle United v Aston Villa: Carver praises rejuvenated visitors|
|Granada v Barcelona: Catalan giants aiming to put pressure back on Real|
|Burnley v Swansea City: Monk targets 40 points in record time|
|Stoke City v Hull City: Meyler focused on maintaining resurgence|
|West Brom v Southampton: Pulis warns of continued dogfight|
|Police identify Chelsea fans over racist chanting|
|Guardiola warns against complacency|
|West Ham v Crystal Palace: Allardyce wary of being caught on counter|
|Parma GM compares club to the Titanic|
|Alderweireld close to Southampton return|
|Dyche keen to move on from Barnes furore|
|Gutierrez in Newcastle squad for Villa clash|
|Union chief urges action over Serbia gun threat|
|Berahino doubtful for Southampton clash|
|German citizenship? Why not? - Ribery|
|League Two Preview: Bury hope winning environment rubs off, Burton host Newport|
|Klopp hoping to avoid any nasty surprises after bomb discovery|
|Blackett pens new United deal|
|Sakho to return to training|
|Flores quits Getafe for personal reasons|
|Busquets agrees new Barcelona deal|
|Martino ´could not be happy´ at Barcelona|
|Allardyce striving to develop more Nobles|
|Nani hopeful of United return|
|Unexploded bomb found near Dortmund stadium|
|Lippi leaves Evergrande for personal reasons|
|Chelsea issue cup final warning to fans|
|Ancelotti has no intention to re-sign Morata|
|Dunkin´ Donuts sorry after Liverpool fans slam alternate club crest|
|Noble signs new West Ham contract|
|Sterling hopeful of contract resolution|
|Ali renews UAE contract|
|Deportivo Saprissa 0 America 3: Visitors win with late blitz|
|Copa Libertadores Review: Pato´s streak continues|
|Chievo v Milan: Abbiati wants consistency from Inzaghi´s men|
|Valverde wants momentum ahead of ´crucial´ week|
|Deila challenges Van Dijk, Denayer|
|Serie A Preview: Roma in crucial clash with Juve, resurgent Inter at home|
|Prince Albert: I feel for Wenger|
|Jardim salutes Monaco´s game plan|
|Schmidt dreaming of UEFA Champions League quarter finals|
|Arsenal face ´extremely difficult´ challenge - Wenger|
|Simeone rues missed Atletico opportunities|
|Berbatov questions Arsenal mentality|
|Calhanoglu confident Leverkusen can progress|
|Nottingham Forest 2 Bournemouth 1: Freedman´s dream start continues|
|Gabi upbeat despite Leverkusen defeat|
|Ligue 1 Preview: Monaco host PSG, Lille look to arrest slump|
|Arsenal 1 Monaco 3: All to do for Wenger´s men after limp first-leg display|
|Bayer Leverkusen 1 Atletico Madrid 0: Calhanoglu gives hosts narrow advantage|
|AFC Champions League Review: Western Sydney off to winning start|
|Piszczek blow for Dortmund|
|Bayern Munich v Cologne: Lewandowski wants more of the same from champions|
|Totti: Feyenoord win can be turning point|
|Icardi can be one of world´s best - Mancini|
|Crowe could ride to Leeds´ rescue|
|Martinez to keep faith with Howard|
|O´Brien fined for dissent in UAE victory|
|La Liga Preview: Messi aims to bounce back from penalty miss, leaders Real host Villarreal|
|Eredivisie Preview: Last chance saloon for De Boer´s Ajax|
|Amnesty International: Qatar must improve labour conditions|
|Greek professional football suspended|
|Liverpool trio out of Besiktas clash|
|Bundesliga Preview: Dortmund set for Ruhr derby, Bayern host Cologne|
|Rami to miss Chievo clash|
|Genoa game will go ahead, says Manenti|
|Neymar involved in spat with City fan|
|Steaua receive stadium ban from UEFA|
|Giaccherini out for majority of season|
|Brighton fined £90,000 for breach of agent rules|
|Chelsea try to identify seven over alleged racist chanting|
|No compensation for clubs over 2022 World Cup|
|Suarez: City fans´ boos helped inspire double|
|Not the right time for Gutierrez yet, says Carver|
|Naismith happy to be in the wars|
|CONCACAF Champions League Review: Pachuca reel in Montreal|
|Copa Libertadores Review: Another Bou hat-trick sees Racing win|
|A-League Preview: Sydney wary of Wanderers ahead of derby|
|Qatar 2022 date change strengthens calls for FIFA overhaul|
|Pellegrini: Champions League tie not over|
|Bresciano calls time on Australia career|
|Barcelona defend Messi´s penalty miss|
|Football League Review: Derby stay two points clear, Middlesbrough bounce back|