Paco Alcacer's hat-trick helped Valencia make UEFA Europa League history by beating Basel 5-3 on aggregate in their quarter-final tie.
No side had ever come from three goals down to win a knockout tie since the advent of the Europa League, but Valencia did just that, triumphing after extra-time courtesy of a 5-0 second-leg win on an extraordinary night at the Mestalla.
Basel boss Murat Yakin had captained the Swiss side in a 6-2 defeat at the same venue 12 years ago and could only watch on in dismay as the visitors, who finished with nine men, imploded.
Alcacer produced a cool finish seven minutes before half-time to give Valencia hope and Edu Vargas made it 2-0 on the night with a powerful header four minutes later.
Both strikers struck the woodwork after the break as Valencia desperately sought to level the tie, eventually doing so in the 70th minute through Alcacer.
Alcacer should have scored again towards the end of 90 minutes, but couldn't convert a one-on-one chance, before Vargas struck the post with the rebound.
An under-pressure Basel then saw Marcelo Diaz and Gaston Sauro see red in the first half of extra-time, and Valencia took full advantage, with Alcacer completing his hat-trick after 113 minutes and Juan Bernat rounding off a remarkable win with a late fifth.
Valencia, who were without Diego Alves, Philippe Senderos and Victor Ruiz, initially struggled to find a way through a resolute Basel defence that had only conceded once in their last five Europa League games.
A frustrated home crowd were brought to life seven minutes before the break, however, when a nicely-weighted pass from Joao Pereira found Alcacer, who beat the offside trap before controlling the ball superbly with his chest and stroking home a cool finish from close range.
That strike clearly gave the hosts a fresh injection of confidence, and the lead should have been extended four minutes later when Vargas' point-blank header was kept out by Yann Sommer.
Vargas made amends for that miss from the resulting corner, rising highest to meet Daniel Parejo's delivery with a towering header into the top-right corner.
The Chilean should have been celebrating again nine minutes after the break when he burst through the heart of the visitors' defence to force an inspired save from Sommer, before clattering the rebound off the post from a tight angle.
Sommer was called into action again on 66 minutes, tipping Alcacer's curling effort from 20 yards onto the crossbar.
But he was beaten four minutes later when a hopeful long ball was brought down by Vargas. He set up Alcacer on the edge of the area, who lashed home an unstoppable shot via the underside of the crossbar.
Alcacer should have completed the comeback in the 88th minute but was denied by Sommer, before Vargas slid in to strike the post again.
Basel were yet again thanking Sommer within the first three minutes of extra-time, the goalkeeper this time denying Parejo after some good work down the left from Bernat.
The visitors then lost their composure and Diaz saw red for an off-the-ball incident before Sauro picked up two bookings in a minute.
Alcacer duly converted a low cross from substitute Pablo Piatti at the near post to give Valencia the lead and a famous win was completed in style when Bernat found himself on the edge of the box, before producing a cool finish to secure his side's place in the semi-finals.
|14||Juan Bernat||115' 118'|
|17||E. Vargas||42' 104'|
|16||Paco Alcácer||38' 70' 113' 114'|
for F. Cartabia 76'
for J. Mathieu 81'
for João Pereira 109'
|Pochettino upbeat despite League Cup defeat|
|Inter 0 Fiorentina 1: Montella´s men end San Siro wait|
|Bundesliga Review: Wolfsburg edge eight-goal thriller, Monchengladbach win|
|Mourinho revels in ´beautiful´ League Cup success|
|Eredivisie Review: PSV lose home record as Ajax close the gap|
|Terry thrilled by ´massive´ League Cup final win|
|Chelsea 2 Tottenham 0: Mourinho´s men seal League Cup success|
|Coquelin sustains broken nose|
|Wenger hails Giroud character after Everton goal|
|Coutinho is coming of age at Anfield - Rodgers|
|Everton not getting what they deserve - Martinez|
|Football League Preview: Wolves in the hunt for back-to-back promotions|
|Norwich City 2 Ipswich Town 0: Neil´s men go third with derby triumph|
|Southampton v Crystal Palace: Fonte focusing on big picture|
|Arsenal 2 Everton 0: Giroud strikes to silence doubters|
|Dynamo Dresden v Borussia Dortmund: Hummels eager to build on derby win|
|Rodgers tips hat to relentless Liverpool|
|City facing uphill challenge to retain title - Pellegrini|
|Celtic 4 Aberdeen 0: Champions dominate top-of-the-table clash|
|Lallana hails ´massive´ win as Liverpool´s top-four charge continues|
|Hull City v Sunderland: Cattermole allowing no excuses against ´bogey team´|
|Liverpool 2 Manchester City 1: Coutinho dents City´s title hopes|
|Sunderland to appeal Brown red card|
|Aston Villa v West Brom: Sherwood looking for confidence boost|
|Allegri not taking risks on Vidal and Pogba|
|Pardew defends Jedinak over Sakho elbow|
|Heldt apologises after Schalke´s derby humbling|
|Milan must give that bit extra - Bocchetti|
|Rooney: Brown red must be rescinded|
|Monk hails Swansea´s versatility|
|Melbourne Victory 2 Wellington Phoenix 3: Hosts miss chance to go top|
|Rodgers: Top-four finish would be bigger than last season´s effort|
|Batman and Robin ´a bit of fun´ - Reus|
|Rakitic feeling better after ending goal drought|
|Copa Libertadores Preview: Well-rested Cruzeiro ready for Universitario|
|Fournier fuming after Lyon loss|
|DFB Pokal Preview: Gladbach visit rusty Offenbach|
|Mourinho: Tottenham approached me|
|Primeira Liga Review: Birthday boys Benfica hit Estoril for six|
|Inzaghi finds positives in lacklustre display|
|Eredivisie Review: AZ move third, Propper fires Vitesse to victory|
|Chievo 0 Milan 0: Pressure back on Inzaghi|
|Bundesliga Review: Derby win for Dortmund superheroes, Leverkusen go fourth|
|Ligue 1 Review: Lyon loss leaves door open for PSG|
|Bueno nets perfect hat-trick in four-goal spree for Rayo|
|Carver impressed with Newcastle´s fighting spirit|
|Van Gaal explains Di Maria decision|
|Luis Enrique angered by Granada pitch|
|Sherwood confident of Villa survival|
|Referee East says ´no mistaken identity´ as Poyet pledges to look again|
|League One Review: Robertson and Johnson off to winning starts, Bristol City go eight clear|
|Bruce angered by missed decision|
|Berahino can be ´top class´ - Pulis|
|Grateful Gutierrez thanks ´special´ fans|
|Monk targets Swansea points record|
|Klopp´s ´perfect´ afternoon|
|Victory soured by Ireland injury, says Hughes|
|Championship Review: Middlesbrough´s opportunity missed as Derby are defeated|
|Koeman: I am realistic on Champions League|
|League Two Review: Burton beaten again, Hartlepool gain welcome lift|
|´Triple punishment´ rule could be scrapped|
|Scottish Premiership Review: Inverness slip up as strugglers prosper|
|Mancini wary of Fiorentina quality|
|Hearts attack hits double figures in Scotland|
|West Brom 1 Southampton 0: Berahino wins it, then limps off|
|Manchester United 2 Sunderland 0: Rooney at the double amid red card controversy|
|Newcastle United 1 Aston Villa 0: Cisse strike downs visitors|
|Stoke City 1 Hull City 0: Super sub Crouch secures win|
|Granada 1 Barcelona 3: Suarez inspires routine win|
|Burnley 0 Swansea City 1: Trippier own goal proves decisive|
|Borussia Dortmund 3 Schalke 0: Late show seals dominant derby win|
|Referee Dowd fails to make it through West Brom, Saints clash|
|Allardyce ´shocked´ after home loss|
|Pardew lauds Murray after ´mixed afternoon´ for striker|
|West Ham 1 Crystal Palace 3: Pardew enjoys more away-day success|
|Blanc: PSG prepared for confident Monaco|
|Ancelotti: Isco place is non-negotiable|
|Pellegrini out to end dismal record at Anfield|
|Roma v Juventus: Matri eyes glory in title tussle|
|Martinez wary of wounded Arsenal|
|A-League Review: Spectacular Sydney derby the highlight|
|Perez to testify in corruption case|
|Bentaleb determined to avoid European hangover|
|Liverpool cannot dwell on Europa exit, says Rodgers|
|Marquinhos welcomes Manchester United interest|
|Tottenham must be ´nearly perfect´ to beat Chelsea - Pochettino|
|Bielsa: I take responsibility|
|League Cup final ´most important´ for Mourinho|
|Rodgers unsure if European exit will be a blessing|
|Vitoria Guimaraes 1 Maritimo 0: Hosts end winless run|
|Guardiola satisfied with Cologne victory|
|Espanyol 1 Cordoba 0: Abraham goal secures the points|
|Marseille 2 Caen 3: Hosts throw lead away yet again|
|Bayern Munich 4 Cologne 1: Champions move 11 points clear|
|Dordrecht 2 Go Ahead Eagles 1: Klaiber leaves it late|
|Luis Enrique laments English ´campaign´ over Suarez|
|Atletico Madrid v Sevilla: Champions attempt to bounce back|
|De Gea dismisses ´lies´ about Van Gaal relationship|
|Monaco v Paris Saint-Germain: Jardim wants no Champions League distractions|
|Inter v Fiorentina: Both sides on a high after Europa League success|
|Real Madrid v Villarreal: Ancelotti´s side looking to keep chasing pack at bay|
|Arsenal v Everton: Hurting Wenger calls for immediate response|
|Hull and Panathinaikos among four clubs pay FFP fines|
|Liverpool v Manchester City: Champions eye long-awaited Anfield success|
|Lucas Moura out for at least four weeks|
|Chelsea v Tottenham: Mourinho´s men channel spirit of 2005|
|Loan move to Ipswich an easy decision for Wood|
|Qatar World Cup final no later than December 18 - Blatter|
|Martinez excited by Kiev draw|
|Dynamo face disciplinary hearing after crowd trouble|
|Hughes close on signing new Stoke deal|
|Parma game called off again|
|De Boer to stay at Ajax|
|Arnesen backs Vieira as potential future City director of football|
|Mourinho has no fears over Wembley referee|
|Van Persie absent for Sunderland clash|
|Mason hoping to relive 2008 at League Cup final|
|Fiorentina and Roma to meet in Europa League|
|Inter finalise Felipe swoop|
|Poyet delighted to have ´contagious´ Cattermole back|
|Melbourne City 3 Adelaide United 1: Baharudin triggers crucial comeback|
|Chelsea can cope with Matic absence - Terry|
|Mancini: I tried to take Guarin to Galatasaray|
|Wilshere undergoes ankle procedure|
|Bruce: Most Championship clubs would struggle with FFP|
|Henry would say yes to Arsenal job|
|Mignolet backs ´devastated´ Liverpool to regroup|
|Tiote looks set to miss the rest of the season|
|Copa Libertadores Review: Osvaldo scores for Boca, Internacional win|
|Alajuelense 5 DC United 2: Costa Ricans set for semis|
|Besiktas settled score with Liverpool - Cenk|
|Montella: Hard to keep Salah|
|Martinez salutes Everton´s qualification|
|Europa League games marred by crowd trouble|