Columbus Crew will look to bounce back from their first loss of the MLS season, when they travel to the San Jose Earthquakes on Sunday.
Crew were humbled 2-0 at home to Toronto last week, but remain top of the Eastern Conference on goal difference from their conquerors, with both on nine points.
Earthquakes sit bottom of the Western Conference, with just one point from three matches.
Although Crew will need to snap a six-match winless run in games against San Jose, with the two sides drawing five of those.
On Saturday, Toronto host the Colorado Rapids at BMO Field.
Six of the past seven contests between the two sides have gone the way of the home side, with Toronto beating the Rapids in all six of their meetings in Canada.
Western Conference leaders Dallas welcome the Seattle Sounders to Texas.
Dallas are four points clear at the top of the table, while the Sounders are riding high after stealing a point from their road trip to Portland Timbers last week as Clint Dempsey's late hat-trick saw them pick up a 4-4 draw.
Real Salt Lake are the only unbeaten side in the league, Dallas aside, and can continue their impressive campaign on the road at Philadelphia Union.
Philadelphia are unbeaten in their past two, but conceded goals in the final 10 minutes in each match to give up maximum points.
Salt Lake came out of their MLS Cup final replay unscathed in a 0-0 draw with Sporting Kansas City, and can stretch their run of minutes without concession beyond 235.
Eastern Conference cellar-dwellers the Montreal Impact can build on back-to-back unbeaten matches when they host the Chicago Fire.
The Impact have two draws to their name after three losses to open the season, while Fire have endured four consecutive stalemates.
The Houston Dynamo will be hungry to snap a two-match losing run, when they travel to the New England Revolution.
DC United enjoyed their first win of the season last weekend, and will look to make it two in a row when they host New York Red Bulls, who have drawn their past four.
The two worst defences in MLS this season, Portland and Chivas USA go head-to-head having both shipped 10 goals in five games.
Los Angeles Galaxy welcome the Vancouver Whitecaps to California.
|Coach: M. Watson|
for C. Cato 46'
for B. Barklage 53'
|Rodgers calls on Liverpool fans to support Sterling|
|Khedira ´frozen out´ by Real|
|Hamstring injury rules Suarez out of Deportivo clash|
|Former Southampton managers hail ´excellent season´|
|Mourinho wants to remain in England after Chelsea|
|Rodgers ´150 per cent sure´ his job is safe|
|Maldini would ´love´ to help Milan|
|Doyle set for Rapids debut versus Whitecaps|
|MLS Review: Champions end winless run on day of late drama|
|Jemez doubted Rayo future|
|Zenga could replace Mihajlovic - Osti|
|Blanc wants to avoid Chelsea-like finish|
|Menez happy in Milan|
|Sherwood: Vlaar wants to stay|
|Arsenal v West Brom: Wenger calls for focus|
|Porto 2 Penafiel 0: Danilo scores in farewell game|
|La Liga Preview: Eibar, Almeria hoping for final-day salvation|
|Eredivisie play-offs: Go Ahead suffer surprise defeat, NAC win|
|South Africa warm up for COSAFA Cup with victory|
|Rodriguez will be like a new signing - Adkins|
|Renard leaves Ivory Coast role amid Lille speculation|
|Howedes doubtful for start of next Bundesliga campaign|
|Deschamps: Pogba and Evra will be happy to face Albania|
|Everton v Tottenham: Pochettino eyeing fifth spot|
|Crystal Palace v Swansea City: Pardew admits to talent envy|
|Van Gaal confident of keeping De Gea|
|Spurs to support Adebayor over family issues|
|Manchester City v Southampton: Koeman expects no favours from hosts|
|Chelsea v Sunderland: Champions set to finally lift trophy|
|Mancini: Inter need quality|
|Van Gaal: No favours for ex-United captain Bruce|
|Leicester City v QPR: Ramsey expects doomed Rangers to show pride|
|Koeman expecting quieter close season|
|Hughes delivers positive update on Bojan|
|Advocaat considering Sunderland offer|
|Hull City v Manchester United: Bruce accepts survival is tall order|
|Stoke City v Liverpool: Rodgers keen to move focus away from Sterling|
|Allardyce won´t let us down, says Bruce|
|Berahino can leave for top-four club - Pulis|
|Aston Villa v Burnley: Sherwood wanting win ahead of cup final|
|Big clubs would be making a ´mistake´ signing Bolasie|
|Peterborough announce Robertson as new manager|
|Relieved Sherwood eager to kick on|
|Newcastle United v West Ham: Carver dreading ´unbearable´ drop|
|Pellegrini unsure over Milner future|
|I am not good enough to win treble every year - Guardiola|
|Luis Enrique refuses to be drawn on Barca future|
|Ntep handed France call-up|
|Allegri compares Juve to class of 2003|
|My future to be decided on Monday - Allardyce|
|Ancelotti expects to stay at Real despite speculation|
|Play-off finals to go ahead despite discovery of World War II bomb|
|Mourinho lauds ´legend´ Lampard|
|Milan v Torino: Shadow of Ancelotti hangs over Inzaghi|
|Speroni extends Palace contract|
|Ramsey issues QPR warning|
|Valverde signs new Bilbao contract|
|Welbeck could miss FA Cup final and England double header|
|League One play-off final Preview: Preston hoping to end hoodoo|
|Rodgers expects Sterling talks to resume|
|Martinez dismisses Oviedo exit talk|
|Neil hoping to draw on previous play-off success|
|Cisse weighing up offers from USA, India and Poland|
|Hazard announced as Premier League´s Player of the Season|
|United should sign Cech if De Gea leaves - Scholes|
|Copa Libertadores Review: Cruzeiro draw first blood away from home|
|MLS Preview: Wondolowski poised for 100-goal club|
|Ligue 1 Preview: Monaco, Marseille, Saint-Etienne battle for Champions League spot|
|Bundesliga Preview: Relegation battle set for dramatic end, Dortmund to farewell Klopp|
|Serie A Preview: Radu in doubt for crucial Rome derby|
|Stankovic denies talk of Inter return|
|Benitez would be ´happy´ to manage Real - agent|
|Newcastle not expecting favours from Allardyce - Carver|
|Lacazette can be ´world class´ - Houllier|
|Hodgson defends Sterling|
|Eredivisie Review: Heerenveen and Vitesse seize initiative|
|Prince Ali confirms World Cup expansion plans|
|Giroud hits back at ´dull´ Henry over Arsenal comments|
|Real Madrid v Getafe: Ancelotti banned in potential Bernabeu farewell|
|Stoke secure permanent Wollscheid deal|
|Ligue 1 relegation places cut to two|
|Bayern Munich v Mainz: Champions out to ring in title with return to form|
|Granada v Atletico Madrid: Tiago ready for difficult final day|
|Luis Figo statement on FIFA president candidacy withdrawal|
|Barcelona v Deportivo La Coruna: Xavi prepares to bid farewell to La Liga|
|New Liverpool deals for Ibe and Flanagan|
|The tooth hurts for Hazard as he looks set to miss Sunderland clash|
|Juventus v Napoli: Double winners prepare to celebrate|
|Luis Figo withdraws from FIFA presidency race|
|Bielsa not expecting contract offer from Marseille|
|Hodgson: No England rift with United over Shaw|
|Genoa v Inter: Mancini´s men chase European berth|
|Borussia Dortmund v Werder Bremen: Klopp looks to sign off with European qualification|
|Bartomeu hits out at Ancelotti to Barca rumours|
|Paris Saint-Germain v Reims: Parisians ready to celebrate title triumph|
|I have not spoken to any clubs, insists Klopp|
|League Two play-off final Preview: Ainsworth claims underdog status|
|Sheringham named Stevenage boss|
|Lawless banned for football betting|
|Defence should be United´s priority, says Stam|
|Klopp vows to ignore nostalgia at final home game|
|Hodgson excited by new England call-ups|
|Xavi: Barca will survive without me|
|Benzema sustains hamstring injury|
|Maiden England call-ups for Austin, Vardy and Heaton|
|Kramer relishing Leverkusen return|
|Xavi confirms Barcelona departure|
|Sterling ´definitely not signing´ new Liverpool deal - agent|
|Herrera eyes second-season improvement|
|Kane plans long Tottenham stay|
|Schmidt signs new Leverkusen deal|
|Sterling should stay at Liverpool, says Redknapp|
|Van Praag withdraws from FIFA presidential race|
|Financial fair play here to stay, warns Platini|
|Zidane: Gerrard and me are alike|
|Drobny ruled out of Hamburg finale|
|Defoe: We want Advocaat to stay|
|Zorc expects Hummels to stay|
|Wilshere happy with position|
|Moreno talks up Europa League|
|Santa Fe 1 Internacional 0: Mosquera nets injury-time winner|
|Sporting Kansas City 4 New England Revolution 2: Nemeth inspires victory|
|Dunga calls up Fred, Felipe Anderson for Olympic trials|
|Koke wants to be Atleti´s Gerrard|
|Tinkler: FFA are ripping off owners|
|Klopp will excel at big club - Feulner|
|Allegri concedes cards fell Juve´s way|
|Estoyanoff cops six-game ACL ban for punching|
|Desailly: Mourinho would have won title with City|
|Teary Advocaat delighted to silence the Sunderland doubters|
|Pioli bemoans Lazio´s lack of luck|
|Chiellini salutes Juve fight after Coppa triumph|