Free-scoring Liverpool must breach one of the Premier League's sternest defences in order to maintain their title charge at West Ham.
Brendan Rodgers' table-toppers are in line for their first top-flight crown since 1990, and head into the final six games of the season knowing a haul of 18 points will be enough to fend off the challenges of Chelsea and Manchester City.
Liverpool's attacking potency is the primary reason for their unexpected title bid, with the Anfield outfit on course to break Chelsea's record of goals in a Premier League season - 103, set in 2009-10.
They have racked up 88 in their 32 top-flight games so far, with lethal strike duo Luis Suarez and Daniel Sturridge - the division's top two scorers - accounting for 49 of those.
A run of eight consecutive wins, with 30 goals scored in the process, has seen Liverpool surge to the summit of the league - and Rodgers has called on his players to focus solely on themselves as the campaign draws to a close.
"We can't afford to worry about other teams, it would be wasting energy to worry about them," the Northern Irishman said.
"It is now about concentrating on performance. The way we are playing gives us great confidence."
Four of Liverpool's 88 Premier League goals came in their 4-1 hammering of West Ham at Anfield in December and they scored three on their last visit to Upton Park.
However, Sam Allardyce's team have often proved a tough nut to crack this season, with only Chelsea able to better their total of 13 clean sheets - although they have failed to shut out their opponents since a 2-0 win over Norwich City on February 11.
West Ham have won six of their last nine top-flight matches, including their last two, meaning they sit 11 points clear of the bottom three and all but safe from relegation with six games to spare.
Andy Carroll, who moved to Upton Park from Liverpool for a club-record fee last June, opened the scoring in West Ham's 2-1 win at Sunderland last Monday, and Allardyce believes the striker - along with fellow ex-Anfield man Stewart Downing - will be eager to prove a point this weekend.
"Those two lads in particularly will want to show how good they are on Sunday. Let's hope they play very, very well on Sunday, because we need them to," he said.
Allardyce looks set to be without George McCartney (hamstring), while James Collins (calf) and Marco Borriello (hamstring) are doubtful.
Rodgers, meanwhile, has a full complement of players to choose from, with the exception of long-term absentee Jose Enrique (knee).
|Coach: S. Allardyce|
for K. Nolan 68'
for M. Taylor 78'
for M. Diamé 84'
|Manchester United´s interest in Griezmann is unsurprising - Simeone|
|Bamford ends spell in Chelsea wilderness with Boro return|
|Louis the great - Luis Enrique explains his and Barca´s debt to Van Gaal|
|Gabon 1 Burkina Faso 1: Spot-on Aubameyang makes his point|
|PSG send Ikone on loan to Montpellier|
|Senegal v Zimbabwe: Cisse wants to live up to favourites tag|
|Ghana´s Rahman leaves AFCON with knee injury|
|Algeria v Tunisia: Mahrez demands improvement in crucial Group B clash|
|Dortmund forward Dembele hits out at Bundesliga refereeing|
|Robben hopes Alonso stays at Bayern amid retirement rumours|
|Asian champions Jeonbuk banned from 2017 Champions League|
|Rakitic still an important player for Barcelona - Luis Enrique|
|Jesus will develop quicker at City - Emerson|
|Always take the weather with you - Spanish snow blights CSKA´s training camp|
|Messi never gave Coach interview, claims father|
|Gotze questions critics but admits to falling short of expecations|
|´Conte can have our title´ - Ranieri wants Chelsea to win the Premier League|
|Tottenham reject Premier League, Bundesliga offers for Wimmer|
|Liverpool sell Ilori to Reading|
|Potential victims in football abuse probe surpasses 500|
|Bonaventura signs new AC Milan contract|
|Messi: Ronaldo has achieved great things|
|Koscielny: Wenger has built men at Arsenal|
|Messi vows to stay at Barcelona ´for as long as they want me´|
|Cafu adamant Neymar will become world´s best|
|I´m just taking a sabbatical - Van Gaal denies he´s retired|
|Not even Gerrard won Premier League - Buttner says he´s not a United flop|
|Samper ignored Wenger as Barca midfielder rejected Arsenal|
|Pleased Pioli wants more from Inter|
|Evergrande boss Scolari dismisses Turan links|
|Klopp seeks legal advice over Matip|
|Marseille complete Sanson move|
|Inter 3 Bologna 2: Candreva prevents remarkable turnaround in Coppa Italia thriller|
|FA Cup Review: Non-league Lincoln stun Ipswich, Burnley and Palace through|
|Gabon v Burkina Faso: Aubameyang says hosts have learned from Guinea-Bissau setback|
|Mali 0 Egypt 0: El-Hadary makes history in stalemate|
|El-Hadary oldest AFCON player ever - 44-year-old Egypt goalkeeper makes history|
|Reus and Gotze on target but Bender injured in Dortmund win|
|Toure shunning lavish China interest to stay at City, says Seluk|
|Rahman´s AFCON in the balance, says Ghana boss Grant|
|Just 14 goals conceded and nine clean sheets - How Vertonghen blow could impact Tottenham|
|Ghana 1 Uganda 0: Andre Ayew hands Black Stars nervy victory|
|Swansea snap up Carroll and Olsson in double swoop|
|All is forgiven? - Costa trains with full Chelsea squad after reported Conte bust-up|
|I would throw myself off a bridge for Luis Enrique - Rakitic dismisses Barca rift rumours|
|Was Juventus´ new logo inspired by tennis star?|
|Smooth sailing for Liverpool in Plymouth? Klopp expects tough test|
|Demichelis re-joins Malaga until end of season|
|Cameroon v Guinea-Bissau: Broos urges new heroes to emerge|
|Boxing champ hits Carragher with Chinese Super League comeback prank|
|Zidane backs Navas and defends Benzema as Madrid aim to bounce back|
|Deportivo bring in Kakuta from Hebei after CSL rule changes|
|Matip could miss eight games without doing anything wrong - Klopp|
|United trigger Valencia´s contract extension|
|Ronaldo returns to Real Madrid´s Copa squad|
|FA fine Sagna for Instagram post|
|Nedved does not foresee more January business for Juventus|
|Rafinha injury blow for Barcelona|
|Villas-Boas fumes at CSL foreign player crackdown|
|Ibrahimovic invaluable to Manchester United youngsters - Rashford|
|Robben rejected China move|
|A-League review: Phoenix rise to the occasion to end Victory´s streak|
|Van Gaal slams English media over treatment at Manchester United|
|Mignolet: Liverpool in better position to win title than in 2013-14|
|Giroud wants Premier League title but understands China temptations|
|Tianjin forced to scrap moves for Costa, Benzema, Cavani and Falcao|
|My goal was better than Mkhitaryan´s - Giroud|
|Pochettino not interested in Argentina job|
|Kane: Tottenham can win Premier League|
|Corinthians dreaming of Drogba - Paulo Roberto|
|Coutinho calls for Liverpool focus|
|Chiellini compares Pogba to LeBron and Bolt|
|Maradona to become Napoli ambassador|
|Mihajlovic furious after Torino collapse|
|Icardi has offers from China - Wanda Nara|
|Pogba can cope with pressure - Ibrahimovic|
|´My half-time words will stay in the dressing room´ - Montella annoyed with AC Milan|
|Juventus unveil dramatic change to club logo - but not everyone´s a fan|
|´I do not think I will return to coaching´ - Van Gaal set to call it quits|
|Torino 2 AC Milan 2: Bacca caps thrilling comeback as hosts pay the penalty|
|DR Congo 1 Morocco 0: Kabananga pounces on blunder to give 10 men the points|
|´Happy and comfortable´ Sanchez dismisses Arsenal exit talk|
|How much?! West Ham flop Simone Zaza could cost Valencia €20m|
|Mali v Egypt: Salah leads Pharaohs´ bid for AFCON glory|
|Sevilla concede they ´cannot force´ sporting director Monchi to stay|
|Ivory Coast 0 Togo 0: Reigning champions held to opening draw by Adebayor and co.|
|Goalkeeping woes, Stones and tactical confusion - How Guardiola is making life difficult for himself|
|Ozil and Sanchez can be persuaded to stay - Cech|
|Pogba: I rejected Barcelona and Real Madrid|
|Ghana v Uganda: Gyan dreams of first trophy since 1982|
|Chiellini: Juventus a work in progress|
|Robben agrees Bayern renewal until 2018|
|Hazard: Goals do not matter to me|
|Bennell pleads not guilty to eight child sex offences|
|Muller fed up with debate over Bayern role|
|Wenger glad Sanchez is not ´a Costa problem´|
|Flick resigns as DFB´s sporting director|
|Gomis ´can´t wait´ to welcome Payet to Marseille|
|Chinese FA changes foreign player rules after ´irrational´ spending|
|Like father, like son: Justin Kluivert follows in dad´s footsteps|
|´No reason to lose him´ - Marotta rubbishes talk of Allegri exit|
|Courtois: We don´t need Costa|
|Kane: Tottenham players won´t go to China|
|Noble ´angry and disappointed´ with Payet|
|Klopp furious over Matip uncertainty|
|Wenger surprised by tight Premier League|
|´Money is not everything´ - Conte issues warning amid China speculation|
|Fiorentina defeat a ´bad setback´ - Allegri|
|´This will elevate this group of players´ - Sampaoli revels in Sevilla late show|